EPS15 (epidermal growth factor receptor pathway substrate 15) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: EPS15 (epidermal growth factor receptor pathway substrate 15) Canis lupus familiaris
Analyze
Symbol: EPS15
Name: epidermal growth factor receptor pathway substrate 15
RGD ID: 12115115
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN endocytic recycling (ortholog); positive regulation of receptor recycling (ortholog); postsynaptic neurotransmitter receptor internalization (ortholog); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; Notch signaling pathway; FOUND IN AP-2 adaptor complex (ortholog); apical plasma membrane (ortholog); basal plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: epidermal growth factor receptor substrate 15
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1159,834,285 - 9,895,755 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl159,787,260 - 9,893,540 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha159,904,456 - 10,047,227 (+)NCBI
ROS_Cfam_1.0159,877,844 - 10,020,742 (+)NCBI
UMICH_Zoey_3.1159,689,665 - 9,832,450 (+)NCBI
UNSW_CanFamBas_1.0159,778,543 - 9,921,371 (+)NCBI
UU_Cfam_GSD_1.0159,794,994 - 9,938,012 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
EPS15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1159,834,285 - 9,895,755 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl159,787,260 - 9,893,540 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha159,904,456 - 10,047,227 (+)NCBI
ROS_Cfam_1.0159,877,844 - 10,020,742 (+)NCBI
UMICH_Zoey_3.1159,689,665 - 9,832,450 (+)NCBI
UNSW_CanFamBas_1.0159,778,543 - 9,921,371 (+)NCBI
UU_Cfam_GSD_1.0159,794,994 - 9,938,012 (+)NCBI
EPS15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl151,354,263 - 51,519,266 (-)EnsemblGRCh38hg38GRCh38
GRCh38151,354,263 - 51,519,275 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37151,819,935 - 51,984,938 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36151,592,523 - 51,757,583 (-)NCBINCBI36hg18NCBI36
Build 34151,531,955 - 51,697,016NCBI
Celera150,106,464 - 50,271,514 (-)NCBI
Cytogenetic Map1p32.3NCBI
HuRef149,937,536 - 50,064,736 (-)NCBIHuRef
CHM1_1151,937,379 - 52,102,411 (-)NCBICHM1_1
Eps15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394109,137,372 - 109,245,014 (+)NCBIGRCm39mm39
GRCm39 Ensembl4109,137,465 - 109,245,014 (+)Ensembl
GRCm384109,280,175 - 109,387,817 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4109,280,268 - 109,387,817 (+)EnsemblGRCm38mm10GRCm38
MGSCv374108,952,880 - 109,060,422 (+)NCBIGRCm37mm9NCBIm37
MGSCv364108,778,235 - 108,883,626 (+)NCBImm8
Celera4107,626,627 - 107,727,939 (+)NCBICelera
Cytogenetic Map4C7NCBI
Eps15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25124,045,865 - 124,146,221 (+)NCBI
Rnor_6.0 Ensembl5128,923,934 - 129,022,054 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05128,923,809 - 129,022,268 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05132,763,094 - 132,861,698 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45130,639,805 - 130,739,014 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15130,645,030 - 130,744,240 (+)NCBI
Celera5122,775,022 - 122,873,141 (+)NCBICelera
Cytogenetic Map5q34-q35NCBI
Eps15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554647,569,566 - 7,688,098 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554647,569,570 - 7,688,098 (+)NCBIChiLan1.0ChiLan1.0
EPS15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1152,097,387 - 52,223,533 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl152,097,387 - 52,223,533 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0150,598,692 - 50,763,585 (-)NCBIMhudiblu_PPA_v0panPan3
Eps15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505865,928,976 - 66,023,422 (-)NCBI
SpeTri2.0NW_0049365229,438,929 - 9,486,781 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPS15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6160,653,890 - 160,801,288 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16160,653,818 - 160,792,516 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26148,356,480 - 148,494,390 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EPS15
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12081,439,017 - 81,599,626 (+)NCBI
ChlSab1.1 Ensembl2081,439,025 - 81,602,710 (+)Ensembl
Vero_WHO_p1.0NW_02366603335,638,865 - 35,801,433 (-)NCBI
Eps15
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248591,584,024 - 1,754,395 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 21 5 6 5 6 6 12 8 10 6
Low 1 1 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_038448207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038621922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038621923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038621925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038621926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_532580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000006237   ⟹   ENSCAFP00000005777
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl159,787,260 - 9,893,540 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000082706   ⟹   ENSCAFP00000062944
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl159,787,260 - 9,893,540 (+)Ensembl
RefSeq Acc Id: XM_038448207   ⟹   XP_038304135
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha159,904,457 - 10,047,227 (+)NCBI
RefSeq Acc Id: XM_038448214   ⟹   XP_038304142
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha159,904,458 - 10,047,227 (+)NCBI
RefSeq Acc Id: XM_038448219   ⟹   XP_038304147
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha159,904,457 - 10,047,227 (+)NCBI
RefSeq Acc Id: XM_038448230   ⟹   XP_038304158
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha159,904,456 - 10,044,887 (+)NCBI
RefSeq Acc Id: XM_038495683   ⟹   XP_038351611
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1159,689,666 - 9,832,450 (+)NCBI
RefSeq Acc Id: XM_038495684   ⟹   XP_038351612
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1159,689,667 - 9,832,450 (+)NCBI
RefSeq Acc Id: XM_038495685   ⟹   XP_038351613
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1159,689,666 - 9,832,450 (+)NCBI
RefSeq Acc Id: XM_038495686   ⟹   XP_038351614
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1159,689,665 - 9,830,110 (+)NCBI
RefSeq Acc Id: XM_038558052   ⟹   XP_038413980
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0159,794,995 - 9,938,012 (+)NCBI
RefSeq Acc Id: XM_038558053   ⟹   XP_038413981
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0159,794,996 - 9,938,012 (+)NCBI
RefSeq Acc Id: XM_038558054   ⟹   XP_038413982
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0159,794,995 - 9,938,012 (+)NCBI
RefSeq Acc Id: XM_038558055   ⟹   XP_038413983
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0159,794,994 - 9,935,672 (+)NCBI
RefSeq Acc Id: XM_038621922   ⟹   XP_038477850
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0159,778,544 - 9,921,371 (+)NCBI
RefSeq Acc Id: XM_038621923   ⟹   XP_038477851
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0159,778,545 - 9,921,371 (+)NCBI
RefSeq Acc Id: XM_038621925   ⟹   XP_038477853
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0159,778,544 - 9,921,371 (+)NCBI
RefSeq Acc Id: XM_038621926   ⟹   XP_038477854
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0159,778,543 - 9,919,031 (+)NCBI
RefSeq Acc Id: XM_038687681   ⟹   XP_038543609
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0159,877,845 - 10,020,742 (+)NCBI
RefSeq Acc Id: XM_038687682   ⟹   XP_038543610
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0159,877,846 - 10,020,742 (+)NCBI
RefSeq Acc Id: XM_038687683   ⟹   XP_038543611
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0159,877,845 - 10,020,742 (+)NCBI
RefSeq Acc Id: XM_038687684   ⟹   XP_038543612
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0159,877,844 - 10,018,402 (+)NCBI
RefSeq Acc Id: XM_532580   ⟹   XP_532580
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1159,834,285 - 9,895,755 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_532580   ⟸   XM_532580
- Sequence:
RefSeq Acc Id: ENSCAFP00000005777   ⟸   ENSCAFT00000006237
RefSeq Acc Id: ENSCAFP00000062944   ⟸   ENSCAFT00000082706
RefSeq Acc Id: XP_038351614   ⟸   XM_038495686
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038351611   ⟸   XM_038495683
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038351613   ⟸   XM_038495685
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038351612   ⟸   XM_038495684
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038477854   ⟸   XM_038621926
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038477850   ⟸   XM_038621922
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038477853   ⟸   XM_038621925
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038477851   ⟸   XM_038621923
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038543612   ⟸   XM_038687684
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038543609   ⟸   XM_038687681
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038543611   ⟸   XM_038687683
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038543610   ⟸   XM_038687682
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038304158   ⟸   XM_038448230
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038304135   ⟸   XM_038448207
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038304147   ⟸   XM_038448219
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038304142   ⟸   XM_038448214
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038413983   ⟸   XM_038558055
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038413980   ⟸   XM_038558052
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038413982   ⟸   XM_038558054
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038413981   ⟸   XM_038558053
- Peptide Label: isoform X2
Protein Domains
EF-hand   EH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003871 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000005777 UniProtKB/TrEMBL
  ENSCAFP00000062944 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000006237 UniProtKB/TrEMBL
  ENSCAFT00000082706 UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  EH_dom UniProtKB/TrEMBL
  UIM_dom UniProtKB/TrEMBL
NCBI Gene EPS15 ENTREZGENE
Pfam EF-hand_4 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PS50031 UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
  SM00027 UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A5F4DAY2_CANLF UniProtKB/TrEMBL
  F1PAM9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:54202 ENTREZGENE