Dusp10 Gene Search Result

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16 records found for search term Dusp10

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1310844	Dusp10	dual specificity phosphatase 10	ENCODES a protein that exhibits JUN kinase binding (ortholog); MAP kinase phosphatase activity (ortholog); mitogen-activated protein kinase p38 binding (ortholog); INVOLVED IN negative regulation of oligodendrocyte differentiation; dephosphorylation (ortholog); negative regulation of epithelial cell ... (more) migration (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH pancreatitis; basal cell carcinoma (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine	13	98145317	98183304	Rat	260	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
1321979	DUSP10	dual specificity phosphatase 10	Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different mem ... (more) bers of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]	1	221701424	221742089	Human	253	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1321980	Dusp10	dual specificity phosphatase 10	Enables MAP kinase phosphatase activity. Involved in several processes, including negative regulation of ERK1 and ERK2 cascade; negative regulation of epithelial cell migration; and negative regulation of epithelium regeneration. Acts upstream of or within several processes, including negative regul ... (more) ation of protein kinase activity; negative regulation of respiratory burst involved in inflammatory response; and negative regulation of stress-activated MAPK cascade. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human DUSP10 (dual specificity phosphatase 10). [provided by Alliance of Genome Resources, Jul 2025]	1	183766575	183807833	Mouse	270	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
9013531	Dusp10	dual specificity phosphatase 10	ENCODES a protein that exhibits JUN kinase binding (ortholog); MAP kinase phosphatase activity (ortholog); mitogen-activated protein kinase p38 binding (ortholog); INVOLVED IN dephosphorylation (ortholog); negative regulation of epithelial cell migration (ortholog); negative regulation of epithelial ... (more) cell proliferation (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); Inflammation (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)	NW_004955520	2338548	2371591	Chinchilla	35	symbol	gene, protein-coding, MODEL [RefSeq]
11701818	DUSP10	dual specificity phosphatase 10	ENCODES a protein that exhibits hydrolase activity (inferred); JUN kinase binding (inferred); MAP kinase phosphatase activity (inferred); INVOLVED IN dephosphorylation (ortholog); negative regulation of JNK cascade (ortholog); negative regulation of JUN kinase activity (ortholog); PARTICIPATES IN c- ... (more) Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); Inflammation (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)	1	197293039	197333828	Bonobo	53	symbol	gene, protein-coding, MODEL [RefSeq]
12276748	DUSP10	dual specificity phosphatase 10	ENCODES a protein that exhibits hydrolase activity (inferred); JUN kinase binding (inferred); MAP kinase phosphatase activity (inferred); INVOLVED IN dephosphorylation (ortholog); negative regulation of JNK cascade (ortholog); negative regulation of JUN kinase activity (ortholog); PARTICIPATES IN c- ... (more) Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); Inflammation (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)	38	16196354	16233640	Dog	52	symbol	gene, protein-coding, MODEL [RefSeq]
12508265	Dusp10	dual specificity phosphatase 10	ENCODES a protein that exhibits hydrolase activity (inferred); JUN kinase binding (inferred); MAP kinase phosphatase activity (inferred); INVOLVED IN dephosphorylation (ortholog); negative regulation of JNK cascade (ortholog); negative regulation of JUN kinase activity (ortholog); PARTICIPATES IN c- ... (more) Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); Inflammation (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)	NW_004936650	679650	718867	Squirrel	53	symbol	gene, protein-coding, MODEL [RefSeq]
18745694	DUSP10	dual specificity phosphatase 10	ENCODES a protein that exhibits hydrolase activity (inferred); JUN kinase binding (inferred); MAP kinase phosphatase activity (inferred); INVOLVED IN dephosphorylation (ortholog); negative regulation of JNK cascade (ortholog); negative regulation of JUN kinase activity (ortholog); PARTICIPATES IN c- ... (more) Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); Inflammation (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)				Green Monkey	53	symbol	gene, protein-coding, MODEL [RefSeq]
18914905	Dusp10	dual specificity phosphatase 10	ENCODES a protein that exhibits JUN kinase binding (ortholog); mitogen-activated protein kinase p38 binding (ortholog); phosphatase activity (ortholog); INVOLVED IN dephosphorylation (ortholog); negative regulation of epithelial cell migration (ortholog); negative regulation of epithelial cell proli ... (more) feration (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); Inflammation (ortholog); FOUND IN nucleoplasm (ortholog)				Naked Mole-Rat	47	symbol	gene, protein-coding, MODEL [RefSeq]
626023377	Dusp10	dual specificity phosphatase 10	ENCODES a protein that exhibits JUN kinase binding (ortholog); MAP kinase phosphatase activity (ortholog); mitogen-activated protein kinase p38 binding (ortholog); INVOLVED IN dephosphorylation (ortholog); negative regulation of epithelial cell migration (ortholog); negative regulation of epithelial ... (more) cell proliferation (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); Inflammation (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)				Black Rat	35	symbol	gene, protein-coding, MODEL [RefSeq]
626468049	dusp10						Tropical Clawed Frog		symbol	gene, null
626468526	dusp10						Tropical Clawed Frog		symbol	gene, null
14210235	DUSP10	dual specificity phosphatase 10	ENCODES a protein that exhibits hydrolase activity (inferred); JUN kinase binding (inferred); MAP kinase phosphatase activity (inferred); INVOLVED IN dephosphorylation (ortholog); negative regulation of JNK cascade (ortholog); negative regulation of JUN kinase activity (ortholog); PARTICIPATES IN c- ... (more) Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); Inflammation (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred); INTERACTS WITH deoxynivalenol; hydrogen peroxide; oleanolic acid				Pig	56	symbol	gene, protein-coding, MODEL [RefSeq]
329332844	dusp10.2						Tropical Clawed Frog		symbol	gene, null
329329976	dusp10.2.L						African Clawed Frog		symbol	gene, null
287253970	dusp10.2.S						African Clawed Frog		symbol	gene, null