| 2479 | Cyp4a2 | cytochrome P450, family 4, subfamily a, polypeptide 2 | ENCODES a protein that exhibits alkane 1-monooxygenase activity; arachidonate binding; arachidonate monooxygenase activity; INVOLVED IN arachidonate metabolic process; icosanoid biosynthetic process; kidney development; PARTICIPATES IN cytochrome P450 monooxygenase mediated pathway of arachidonic ac id metabolism; linoleic acid metabolic pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH autosomal recessive polycystic kidney disease; Vitamin A Deficiency; FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2,2-tetramine | 5 | 134160356 | 134170908 | Rat | 107 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 41339692 | Cyp4a2-ps1 | cytochrome P450, family 4, subfamily a, polypeptide 2, pseudogene 1 | | 5 | 134203760 | 134212182 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 40980620 | Cyp4a2-ps2 | cytochrome P450, family 4, subfamily a, polypeptide 2, pseudogene 2 | | 5 | 134290661 | 134299013 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 5687724 | Cyp4a2em1Mcwi | cytochrome P450, family 4, subfamily a, polypeptide 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin | This allele was made by ZFN mutagenesis. The resulting mutation is a net 2-bp frameshift deletion in exon 2 (del 319-320) | | | | Rat | | symbol , old_gene_symbol | gene, allele |
| 730831 | CYP4A11 | cytochrome P450 family 4 subfamily A member 11 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxy lates medium-chain fatty acids such as laurate and myristate. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016] | 1 | 46929188 | 46941476 | Human | 189 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1613889 | Cyp4a28-ps | cytochrome P450, family 4, subfamily a, polypeptide 28, pseudogene | | 4 | 114995761 | 115013702 | Mouse | | symbol , PhenoGen , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1626605 | Cyp4a29 | cytochrome P450, family 4, subfamily a, polypeptide 29 | Predicted to enable 16-hydroxypalmitate dehydrogenase activity and monooxygenase activity. Predicted to be involved in fatty acid metabolic process; icosanoid biosynthetic process; and kidney development. Predicted to be located in apical plasma membrane; cytoplasm; and extracellular space. Predicte d to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11) and CYP4A22 (cytochrome P450 family 4 subfamily A member 22). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 115099241 | 115112138 | Mouse | 31 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 731279 | Cyp4x1 | cytochrome P450, family 4, subfamily x, polypeptide 1 | Predicted to enable anandamide 14,15 epoxidase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including genitourinary system; heart; nervous system; and neural retina. Orthologous to human CYP4X1 (cytochrome P450 family 4 subfamily X member 1). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 114963518 | 114991276 | Mouse | 85 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 14247792 | CYP4A21 | cytochrome P450 family 4 subfamily A member 21 | ENCODES a protein that exhibits heme binding (inferred); iron ion binding (inferred); metal ion binding (inferred); INVOLVED IN lipid metabolic process (inferred); FOUND IN endoplasmic reticulum membrane (inferred) | | | | Pig | 12 | symbol , ensembl_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1603864 | CYP4A22 | cytochrome P450 family 4 subfamily A member 22 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chro mosome 1p33. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] | 1 | 47137441 | 47149727 | Human | 288 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 11959881 | CYP4A22 | cytochrome P450 family 4 subfamily A member 22 | ENCODES a protein that exhibits alkane 1-monooxygenase activity (ortholog); arachidonate monooxygenase activity (ortholog); arachidonate omega-hydroxylase activity (ortholog); INVOLVED IN arachidonate metabolic process (ortholog); icosanoid biosynthetic process (ortholog); kidney development (orthol og); PARTICIPATES IN cytochrome P450 monooxygenase mediated pathway of arachidonic acid metabolism; linoleic acid metabolic pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal recessive polycystic kidney disease (ortholog); hypertension (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); extracellular space (inferred) | 1 | 46442854 | 46455153 | Bonobo | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18547692 | CYP4A22 | cytochrome P450 family 4 subfamily A member 22 | | | | | Green Monkey | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 38542909 | CYP4A22 | cytochrome P450 family 4 subfamily A member 22 | ENCODES a protein that exhibits alkane 1-monooxygenase activity (inferred); arachidonate monooxygenase activity (inferred); heme binding (inferred); INVOLVED IN arachidonate metabolic process (inferred); icosanoid biosynthetic process (inferred); kidney development (inferred); FOUND IN endoplasmic r eticulum membrane (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding |
| 14089674 | CYP4A23 | cytochrome P450 family 4 subfamily A member 23 | ENCODES a protein that exhibits heme binding (inferred); iron ion binding (inferred); metal ion binding (inferred); INVOLVED IN lipid metabolic process (inferred); FOUND IN endoplasmic reticulum membrane (inferred) | | | | Pig | 10 | symbol , ensembl_gene_symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14242260 | CYP4A24 | cytochrome P450 family 4 subfamily A member 24 | ENCODES a protein that exhibits heme binding (inferred); iron ion binding (inferred); long-chain fatty acid omega-hydroxylase activity (inferred); INVOLVED IN lipid metabolic process (inferred); FOUND IN endoplasmic reticulum membrane (inferred) | | | | Pig | 12 | symbol , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 10402017 | CYP4A26P | cytochrome P450 family 4 subfamily A member 26, pseudogene | | 1 | 46967481 | 46967866 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 11038761 | CYP4A27P | cytochrome P450 family 4 subfamily A member 27, pseudogene | | 1 | 47000898 | 47001087 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 41366809 | Cyp4a2l1 | cytochrome P450, family 4, subfamily a, polypeptide 2 like 1 | ENCODES a protein that exhibits heme binding (inferred); iron ion binding (inferred); long-chain fatty acid omega-hydroxylase activity (inferred); INVOLVED IN fatty acid metabolic process (inferred); FOUND IN endoplasmic reticulum membrane (inferred) | 5 | 134247240 | 134257826 | Rat | 19 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 38640948 | CYP4A22-AS1 | CYP4A22 antisense RNA 1 | INTERACTS WITH aristolochic acid A; propofol | 1 | 47095540 | 47179623 | Human | 2 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 15555154 | Cyp4a29-ps1 | cytochrome P450, family 4, subfamily a, polypeptide 29, pseudogene 1 | | | | | Mouse | | symbol , PhenoGen | gene, unprocessed_pseudogene |
| 68945 | Cyp4a1 | cytochrome P450, family 4, subfamily a, polypeptide 1 | ENCODES a protein that exhibits alkane 1-monooxygenase activity; arachidonate monooxygenase activity; 16-hydroxypalmitate dehydrogenase activity (ortholog); INVOLVED IN arachidonate metabolic process; icosanoid biosynthetic process; kidney development; PARTICIPATES IN cytochrome P450 monooxygenase m ediated pathway of arachidonic acid metabolism; linoleic acid metabolic pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH autosomal recessive polycystic kidney disease; hypertension; autism spectrum disorder (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; 1-benzylpiperazine; 1-naphthyl isothiocyanate | 5 | 134360096 | 134374233 | Rat | 228 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1354200 | CYP4Z1 | cytochrome P450 family 4 subfamily Z member 1 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chro mosome 1p33. [provided by RefSeq, Jul 2008] | 1 | 47055525 | 47118318 | Human | 44 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 735593 | Cyp4a10 | cytochrome P450, family 4, subfamily a, polypeptide 10 | Predicted to enable monooxygenase activity. Predicted to be involved in several processes, including fatty acid metabolic process; icosanoid metabolic process; and positive regulation of icosanoid secretion. Located in intracellular membrane-bounded organelle. Is expressed in liver and urinary syste m. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11) and CYP4A22 (cytochrome P450 family 4 subfamily A member 22). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 115375484 | 115390846 | Mouse | 226 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1558005 | Cyp4a12a | cytochrome P450, family 4, subfamily a, polypeptide 12a | Enables alkane 1-monooxygenase activity and arachidonate omega-hydroxylase activity. Involved in omega-hydroxylase P450 pathway. Predicted to be located in apical plasma membrane; endoplasmic reticulum membrane; and extracellular space. Predicted to be active in intracellular membrane-bounded organe lle. Is expressed in liver; metanephros; nervous system; nose; and respiratory system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11) and CYP4A22 (cytochrome P450 family 4 subfamily A member 22). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 115156243 | 115190012 | Mouse | 107 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1623316 | Cyp4a12b | cytochrome P450, family 4, subfamily a, polypeptide 12B | Enables arachidonate omega-hydroxylase activity. Involved in omega-hydroxylase P450 pathway. Predicted to be located in apical plasma membrane; endoplasmic reticulum membrane; and extracellular space. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in liver; metaneph ros; nervous system; nose; and respiratory system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11) and CYP4A22 (cytochrome P450 family 4 subfamily A member 22). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 115268821 | 115296231 | Mouse | 261 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1550175 | Cyp4a14 | cytochrome P450, family 4, subfamily a, polypeptide 14 | Predicted to enable 16-hydroxypalmitate dehydrogenase activity; arachidonate binding activity; and monooxygenase activity. Predicted to be involved in fatty acid metabolic process; icosanoid biosynthetic process; and kidney development. Predicted to be located in apical plasma membrane; cytoplasm; a nd extracellular space. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including adrenal gland; gut; hemolymphoid system gland; liver; and lung. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11) and CYP4A22 (cytochrome P450 family 4 subfamily A member 22). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 115343397 | 115353355 | Mouse | 214 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1626604 | Cyp4a30b | cytochrome P450, family 4, subfamily a, polypeptide 30b | Predicted to enable 16-hydroxypalmitate dehydrogenase activity and monooxygenase activity. Predicted to be involved in fatty acid metabolic process; icosanoid biosynthetic process; and kidney development. Predicted to be located in apical plasma membrane; cytoplasm; and extracellular space. Predicte d to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11) and CYP4A22 (cytochrome P450 family 4 subfamily A member 22). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 115309688 | 115328615 | Mouse | 37 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1616344 | Cyp4a31 | cytochrome P450, family 4, subfamily a, polypeptide 31 | Predicted to enable monooxygenase activity. Predicted to be involved in several processes, including fatty acid metabolic process; icosanoid metabolic process; and positive regulation of icosanoid secretion. Predicted to be located in apical plasma membrane and cytoplasm. Predicted to be active in i ntracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11) and CYP4A22 (cytochrome P450 family 4 subfamily A member 22). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 115420824 | 115436212 | Mouse | 152 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2293816 | Cyp4a32 | cytochrome P450, family 4, subfamily a, polypeptide 32 | Predicted to enable monooxygenase activity. Predicted to be involved in several processes, including fatty acid metabolic process; icosanoid metabolic process; and positive regulation of icosanoid secretion. Predicted to be located in apical plasma membrane and cytoplasm. Predicted to be active in i ntracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11) and CYP4A22 (cytochrome P450 family 4 subfamily A member 22). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 115458124 | 115479704 | Mouse | 70 | description | gene, protein-coding, VALIDATED [RefSeq] |