| 1305050 | Chmp2a | charged multivesicular body protein 2A | ENCODES a protein that exhibits membrane bending activity (ortholog); phosphatidylcholine binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); establishment of protein localization (ortholog); PARTICIPATES IN endocytos is pathway; FOUND IN amphisome membrane (ortholog); autophagosome membrane (ortholog); chromatin (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amphetamine | 1 | 82731212 | 82735088 | Rat | 101 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1550598 | Chmp2a | charged multivesicular body protein 2A | Predicted to enable phosphatidylcholine binding activity and protein domain specific binding activity. Predicted to be involved in several processes, including mitotic nuclear division; regulation of cell cycle process; and vacuolar transport. Located in cytosol. Is expressed in several structures, including branchial arch; facial prominence; ganglia; gut; and limb bud. Orthologous to human CHMP2A (charged multivesicular body protein 2A). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 12765933 | 12768704 | Mouse | 172 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1603659 | CHMP2A | charged multivesicular body protein 2A | CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008] | 19 | 58551566 | 58555105 | Human | 151 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8932825 | Chmp2a | charged multivesicular body protein 2A | ENCODES a protein that exhibits membrane bending activity (ortholog); phosphatidylcholine binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); establishment of protein localization (ortholog); FOUND IN amphisome membra ne (ortholog); autophagosome membrane (ortholog); chromatin (ortholog) | NW_004955584 | 1156828 | 1160056 | Chinchilla | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11746732 | CHMP2A | charged multivesicular body protein 2A | ENCODES a protein that exhibits membrane bending activity (inferred); phosphatidylcholine binding (inferred); protein domain specific binding (inferred); INVOLVED IN autophagosome maturation (inferred); autophagy (inferred); establishment of protein localization (inferred); FOUND IN amphisome membra ne (inferred); autophagosome membrane (inferred); chromatin (inferred) | 19 | 55564622 | 55568214 | Bonobo | 76 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12373226 | CHMP2A | charged multivesicular body protein 2A | ENCODES a protein that exhibits membrane bending activity (inferred); phosphatidylcholine binding (inferred); protein domain specific binding (inferred); INVOLVED IN autophagosome maturation (inferred); autophagy (inferred); establishment of protein localization (inferred); FOUND IN amphisome membra ne (inferred); autophagosome membrane (inferred); chromatin (inferred) | 1 | 99405322 | 99408257 | Dog | 63 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12710248 | Chmp2a | charged multivesicular body protein 2A | ENCODES a protein that exhibits membrane bending activity (ortholog); phosphatidylcholine binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); establishment of protein localization (ortholog); FOUND IN amphisome membra ne (ortholog); autophagosome membrane (ortholog); chromatin (ortholog) | NW_004937062 | 133361 | 136329 | Squirrel | 59 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18511534 | CHMP2A | charged multivesicular body protein 2A | ENCODES a protein that exhibits membrane bending activity (inferred); phosphatidylcholine binding (inferred); protein domain specific binding (inferred); INVOLVED IN autophagosome maturation (inferred); autophagy (inferred); establishment of protein localization (inferred); FOUND IN amphisome membra ne (inferred); autophagosome membrane (inferred); chromatin (inferred) | | | | Green Monkey | 76 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155233200 | chmp2a | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14061157 | CHMP2A | charged multivesicular body protein 2A | ENCODES a protein that exhibits membrane bending activity (inferred); phosphatidylcholine binding (inferred); protein domain specific binding (inferred); INVOLVED IN autophagosome maturation (inferred); autophagy (inferred); establishment of protein localization (inferred); FOUND IN amphisome membra ne (inferred); autophagosome membrane (inferred); chromatin (inferred) | | | | Pig | 63 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18905574 | Chmp2a | charged multivesicular body protein 2A | ENCODES a protein that exhibits membrane bending activity (ortholog); phosphatidylcholine binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); establishment of protein localization (ortholog); FOUND IN amphisome membra ne (ortholog); autophagosome membrane (ortholog); chromatin (ortholog) | | | | Naked Mole-Rat | 59 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626019654 | Chmp2a | charged multivesicular body protein 2A | ENCODES a protein that exhibits membrane bending activity (ortholog); phosphatidylcholine binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); establishment of protein localization (ortholog); FOUND IN amphisome membra ne (ortholog); autophagosome membrane (ortholog); chromatin (ortholog) | | | | Black Rat | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155249757 | chmp2a.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155247997 | chmp2a.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 18934806 | Rad23b | RAD23 nucleotide excision repair protein B | ENCODES a protein that exhibits DNA damage sensor activity (ortholog); histone H4K20 demethylase activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to interleukin-7 (ortholog); DNA damage response (ortholog); embryonic organ development (ortholog); PARTICIPATES IN nucleotide excision repair pathway; ASSOCIATED WITH Craniofacial Abnormalities (ortholog); male infertility (ortholog); Prostatic Neoplasms (ortholog); FOUND IN XPC complex (ortholog) | | | | Naked Mole-Rat | 55 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |