Vom2r-ps45 (vomeronasal 2 receptor, pseudogene 45) - Rat Genome Database

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Gene: Vom2r-ps45 (vomeronasal 2 receptor, pseudogene 45) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r-ps45
Name: vomeronasal 2 receptor, pseudogene 45
RGD ID: 708402
Description: Predicted to be involved in G protein-coupled receptor signaling pathway; INTERACTS WITH ammonium chloride; Muraglitazar; Tesaglitazar.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: LOC286982; putative pheromone receptor (Go-VN6); vomeronasal 2 receptor 45 pseudogene; vomeronasal 2 receptor pseudogene 45
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8175,496,310 - 75,523,783 (+)NCBIGRCr8
mRatBN7.2166,463,177 - 66,490,650 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,463,277 - 66,490,550 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx171,814,608 - 71,842,087 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0180,451,669 - 80,479,140 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0173,661,195 - 73,688,578 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0169,496,309 - 69,523,063 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0170,894,608 - 70,920,347 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4164,855,443 - 64,883,084 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1164,933,539 - 64,961,992 (+)NCBI
Celera164,229,170 - 64,247,962 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r-ps45Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of VOM2R-PS45 mRNACTDPMID:16483693
Vom2r-ps45RatMuraglitazar decreases expressionEXP 6480464muraglitazar results in decreased expression of VOM2R-PS45 mRNACTDPMID:21515302
Vom2r-ps45RatTesaglitazar decreases expressionEXP 6480464tesaglitazar results in decreased expression of VOM2R-PS45 mRNACTDPMID:21515302
Vom2r-ps45Rattroglitazone decreases expressionEXP 6480464troglitazone results in decreased expression of VOM2R-PS45 mRNACTDPMID:21515302


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r-ps45RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000068 more ...1600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r-ps45Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Vom2r-ps45Ratmembrane located_inIEAInterPro:IPR000068 and InterPro:IPR0040731600115GO_REF:0000002InterProGO_REF:0000002
Vom2r-ps45Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Vom2r-ps45Ratplasma membrane is_active_inIBAMGI:2429498 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r-ps45RatG protein-coupled receptor activity enablesIBAMGI:2429498 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Vom2r-ps45RatG protein-coupled receptor activity enablesIEAInterPro:IPR000068 more ...1600115GO_REF:0000002InterProGO_REF:0000002


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A novel family of putative pheromone receptors in mammals with a topographically organized and sexually dimorphic distribution. Herrada G and Dulac C, Cell 1997 Aug 22;90(4):763-73.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:15057822   PMID:17382427  



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Variants in Vom2r-ps45
568 total Variants

1 to 10 of 47 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat

1 to 10 of 47 rows






RefSeq Acc Id: XR_590097
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0169,496,423 - 69,522,162 (+)NCBI
RefSeq Acc Id: XR_598732
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera164,229,284 - 64,247,061 (+)NCBI
GenBank Protein AAC53330 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000091361.1
GPCR family 3 nine cysteines   Receptor ligand binding region


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 23 of 23 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-60978 BioCyc
Ensembl Genes ENSRNOG00000009146 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000075332 ENTREZGENE
Ensembl Transcript ENSRNOT00000119254.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene 286982 ENTREZGENE
PANTHER EC2-V2R PHEROMONE RECEPTOR PROTEIN-RELATED UniProtKB/TrEMBL
  PTHR24061 UniProtKB/TrEMBL
Pfam ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vom2r-ps45 PhenoGen
PRINTS VOMERONASL2R UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009146 RatGTEx
  ENSRNOG00000075332 RatGTEx
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A0A8I6ABH3_RAT UniProtKB/TrEMBL
1 to 23 of 23 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-07-23 Vom2r-ps45  vomeronasal 2 receptor, pseudogene 45    vomeronasal 2 receptor pseudogene 45  Symbol and Name updated 1299863 APPROVED
2008-07-02 Vom2r-ps45  vomeronasal 2 receptor pseudogene 45  Vom2r-ps45  vomeronasal 2 receptor 45 pseudogene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-01 Vom2r-ps45  vomeronasal 2 receptor 45 pseudogene  LOC286982  putative pheromone receptor (Go-VN6)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-10-12 LOC286982        Symbol and Name status set to provisional 70820 PROVISIONAL