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Gene: Gp2 (glycoprotein 2) Rattus norvegicus

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Symbol:

Gp2

Name:

glycoprotein 2

RGD ID:

621695

Description:

Predicted to enable antigen binding activity. Predicted to be involved in neutrophil migration. Predicted to act upstream of or within antigen transcytosis by M cells in mucosal-associated lymphoid tissue and establishment of localization in cell. Located in external side of plasma membrane and zymogen granule membrane. Orthologous to human GP2 (glycoprotein 2); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 7,12-dimethyltetraphene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

glycoprotein 2 (zymogen granule membrane); glycoprotein 80; GP80; pancreatic secretory granule membrane major glycoprotein GP2; pancreatic zymogen granule membrane protein GP-2; secretory (zymogen) granule membrane glycoprotein GP2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GP2 (glycoprotein 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Treefam
Mus musculus (house mouse):	Gp2 (glycoprotein 2 zymogen granule membrane)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gp2 (glycoprotein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GP2 (glycoprotein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GP2 (glycoprotein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gp2 (glycoprotein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GP2 (glycoprotein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GP2 (glycoprotein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gp2 (glycoprotein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	UMOD (uromodulin)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Gp2 (glycoprotein 2 zymogen granule membrane)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GP2 (glycoprotein 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zgc:153932	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-239b22.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-226h7.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	umod.1	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	umod.3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	183,228,395 - 183,243,954 (-)	NCBI		GRCr8
mRatBN7.2	1	173,797,057 - 173,812,619 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	173,797,057 - 173,812,619 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	182,107,960 - 182,123,570 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	189,294,066 - 189,309,672 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	182,029,288 - 182,044,898 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	189,166,735 - 189,182,306 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	189,166,399 - 189,182,306 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	196,108,647 - 196,127,738 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	177,709,931 - 177,725,490 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	177,849,176 - 177,864,736 (-)	NCBI
Celera	1	171,549,813 - 171,565,349 (-)	NCBI		Celera
Cytogenetic Map	1	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Gp2	Rat	Body Weight		ISO	GP2 (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:22344219
Gp2	Rat	type 2 diabetes mellitus		ISO	GP2 (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:30718926

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Gp2	Rat	1,2-dimethylhydrazine	decreases expression	ISO	Gp2 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in decreased expression of GP2 mRNA	CTD	PMID:22206623
Gp2	Rat	17beta-estradiol	multiple interactions	EXP		6480464	[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of GP2 mRNA and [Estradiol co-treated with Plant Preparations] results in increased expression of GP2 mRNA	CTD	PMID:26945725 and PMID:32741896
Gp2	Rat	17beta-estradiol	decreases expression	ISO	Gp2 (Mus musculus)	6480464	Estradiol results in decreased expression of GP2 mRNA	CTD	PMID:39298647
Gp2	Rat	17beta-estradiol	increases expression	EXP		6480464	Estradiol results in increased expression of GP2 mRNA	CTD	PMID:26945725
Gp2	Rat	17beta-estradiol 3-benzoate	multiple interactions	EXP		6480464	[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of GP2 mRNA	CTD	PMID:32741896
Gp2	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	Gp2 (Mus musculus)	6480464	bisphenol S results in decreased expression of GP2 mRNA	CTD	PMID:39298647
Gp2	Rat	7,12-dimethyltetraphene	increases expression	EXP		6480464	9 more ...	CTD	PMID:19480007
Gp2	Rat	acrylamide	decreases expression	EXP		6480464	Acrylamide results in decreased expression of GP2 mRNA	CTD	PMID:28959563
Gp2	Rat	alpha-Zearalanol	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of GP2 mRNA	CTD	PMID:35163327
Gp2	Rat	ammonium chloride	affects expression	EXP		6480464	Ammonium Chloride affects the expression of GP2 mRNA	CTD	PMID:16483693
Gp2	Rat	arsane	affects methylation	ISO	GP2 (Homo sapiens)	6480464	Arsenic affects the methylation of GP2 gene	CTD	PMID:25304211
Gp2	Rat	arsenic atom	affects methylation	ISO	GP2 (Homo sapiens)	6480464	Arsenic affects the methylation of GP2 gene	CTD	PMID:25304211
Gp2	Rat	benzo[a]pyrene	decreases expression	ISO	Gp2 (Mus musculus)	6480464	Benzo(a)pyrene results in decreased expression of GP2 mRNA	CTD	PMID:22228805
Gp2	Rat	benzo[a]pyrene	increases methylation	ISO	GP2 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of GP2 5' UTR	CTD	PMID:27901495
Gp2	Rat	benzo[a]pyrene	decreases methylation	ISO	GP2 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of GP2 3' UTR	CTD	PMID:27901495
Gp2	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of GP2 mRNA	CTD	PMID:18180321
Gp2	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of GP2 mRNA	CTD	PMID:25181051
Gp2	Rat	carbon nanotube	decreases expression	ISO	Gp2 (Mus musculus)	6480464	Nanotubes and Carbon analog results in decreased expression of GP2 mRNA	CTD	PMID:25620056
Gp2	Rat	carbon nanotube	increases expression	ISO	Gp2 (Mus musculus)	6480464	Nanotubes and Carbon results in increased expression of GP2 mRNA	CTD	PMID:25620056
Gp2	Rat	CGP 52608	multiple interactions	ISO	GP2 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to GP2 gene]	CTD	PMID:28238834
Gp2	Rat	chloroprene	increases expression	ISO	Gp2 (Mus musculus)	6480464	Chloroprene results in increased expression of GP2 mRNA	CTD	PMID:23125180
Gp2	Rat	cocaine	affects expression	EXP		6480464	Cocaine affects the expression of GP2 mRNA	CTD	PMID:20187946
Gp2	Rat	glyphosate	decreases expression	ISO	Gp2 (Mus musculus)	6480464	Glyphosate results in decreased expression of GP2 mRNA	CTD	PMID:35489704
Gp2	Rat	hydralazine	multiple interactions	ISO	GP2 (Homo sapiens)	6480464	[Hydralazine co-treated with Valproic Acid] results in increased expression of GP2 mRNA	CTD	PMID:17183730
Gp2	Rat	indole-3-methanol	multiple interactions	EXP		6480464	[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GP2 mRNA	CTD	PMID:22129741
Gp2	Rat	N-acetyl-L-cysteine	multiple interactions	EXP		6480464	[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GP2 mRNA	CTD	PMID:22129741
Gp2	Rat	N-nitrosodiethylamine	multiple interactions	EXP		6480464	[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GP2 mRNA	CTD	PMID:22129741
Gp2	Rat	ozone	multiple interactions	ISO	Gp2 (Mus musculus)	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of GP2 mRNA	CTD	PMID:34911549
Gp2	Rat	ozone	increases expression	ISO	Gp2 (Mus musculus)	6480464	Ozone results in increased expression of GP2 mRNA	CTD	PMID:33026818
Gp2	Rat	paracetamol	increases expression	ISO	GP2 (Homo sapiens)	6480464	Acetaminophen results in increased expression of GP2 mRNA	CTD	PMID:26690555
Gp2	Rat	paraquat	increases expression	EXP		6480464	Paraquat results in increased expression of GP2 mRNA	CTD	PMID:32680482
Gp2	Rat	perfluorooctanoic acid	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of GP2 mRNA	CTD	PMID:35163327
Gp2	Rat	pioglitazone	multiple interactions	ISO	Gp2 (Mus musculus)	6480464	[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GP2 mRNA	CTD	PMID:27935865
Gp2	Rat	pirinixic acid	multiple interactions	ISO	Gp2 (Mus musculus)	6480464	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of GP2 mRNA	CTD	PMID:19710929
Gp2	Rat	pirinixic acid	increases expression	ISO	Gp2 (Mus musculus)	6480464	pirinixic acid results in increased expression of GP2 mRNA	CTD	PMID:17426115
Gp2	Rat	sodium arsenite	increases expression	ISO	Gp2 (Mus musculus)	6480464	sodium arsenite results in increased expression of GP2 mRNA	CTD	PMID:37682722
Gp2	Rat	sodium dichromate	increases expression	EXP		6480464	sodium bichromate results in increased expression of GP2 mRNA	CTD	PMID:22561333
Gp2	Rat	testosterone	multiple interactions	EXP		6480464	[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of GP2 mRNA	CTD	PMID:32741896
Gp2	Rat	thalidomide	increases expression	ISO	Gp2 (Mus musculus)	6480464	Thalidomide results in increased expression of GP2 mRNA	CTD	PMID:26217789
Gp2	Rat	titanium dioxide	decreases expression	ISO	Gp2 (Mus musculus)	6480464	titanium dioxide results in decreased expression of GP2 mRNA	CTD	PMID:23557971
Gp2	Rat	titanium dioxide	increases expression	EXP		6480464	titanium dioxide results in increased expression of GP2 mRNA	CTD	PMID:30012374
Gp2	Rat	titanium dioxide	increases expression	ISO	Gp2 (Mus musculus)	6480464	titanium dioxide results in increased expression of GP2 mRNA	CTD	PMID:27760801
Gp2	Rat	urethane	decreases expression	ISO	GP2 (Homo sapiens)	6480464	Urethane results in decreased expression of GP2 mRNA	CTD	PMID:28818685
Gp2	Rat	valproic acid	multiple interactions	ISO	GP2 (Homo sapiens)	6480464	[Hydralazine co-treated with Valproic Acid] results in increased expression of GP2 mRNA	CTD	PMID:17183730

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Gp2	Rat	antigen transcytosis by M cells in mucosal-associated lymphoid tissue	acts_upstream_of_or_within	ISO	Gp2 (Mus musculus)	1624291	PMID:19907495	RGD	PMID:19907495
Gp2	Rat	establishment of localization in cell	acts_upstream_of_or_within	ISO	Gp2 (Mus musculus)	1624291	PMID:19907495	RGD	PMID:19907495
Gp2	Rat	immune system process	involved_in	IEA	UniProtKB-KW:KW-0391	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Gp2	Rat	innate immune response	involved_in	IEA	UniProtKB-KW:KW-0399	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Gp2	Rat	neutrophil migration	involved_in	IBA	PANTHER:PTN002546428 and UniProtKB:P07911	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Gp2	Rat	apical plasma membrane	part_of	ISO	GP2 (Homo sapiens)	1624291	PMID:19907495	RGD	PMID:19907495
Gp2	Rat	apical plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0015	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Gp2	Rat	apical plasma membrane	part_of	IEA	UniProtKB:P55259 and ensembl:ENSP00000304044	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Gp2	Rat	apical plasma membrane	is_active_in	IBA	MGI:102674 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Gp2	Rat	apical plasma membrane	located_in	ISO	Gp2 (Mus musculus)	1624291	PMID:19907495	RGD	PMID:19907495
Gp2	Rat	cell periphery	located_in	IEA	ARBA:ARBA00027443	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Gp2	Rat	cell surface	is_active_in	IBA	MGI:1929785 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Gp2	Rat	cytoplasmic vesicle	located_in	IEA	UniProtKB-KW:KW-0968	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Gp2	Rat	endosome	located_in	ISO	GP2 (Homo sapiens)	1624291	PMID:19907495	RGD	PMID:19907495
Gp2	Rat	endosome	located_in	IEA	UniProtKB-SubCell:SL-0101	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Gp2	Rat	endosome	located_in	ISO	Gp2 (Mus musculus)	1624291	PMID:19907495	RGD	PMID:19907495
Gp2	Rat	endosome	located_in	IEA	UniProtKB-KW:KW-0967	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Gp2	Rat	endosome	located_in	IEA	UniProtKB:P55259 and ensembl:ENSP00000304044	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Gp2	Rat	endosome	located_in	ISS	UniProtKB:Q9D733	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Gp2	Rat	external side of plasma membrane	located_in	IDA		633018	PMID:1999417	UniProt
Gp2	Rat	external side of plasma membrane	located_in	ISO	GP2 (Canis lupus familiaris)	1624291	PMID:2011597	RGD	PMID:2011597
Gp2	Rat	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Gp2	Rat	extracellular region	located_in	IEA	UniProtKB-KW:KW-0964	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Gp2	Rat	extracellular space	located_in	ISS	UniProtKB:P25291	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Gp2	Rat	extracellular space	is_active_in	IBA	MGI:102674 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Gp2	Rat	extracellular space	located_in	ISO	GP2 (Canis lupus familiaris)	1624291	PMID:2011597	RGD	PMID:2011597
Gp2	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Gp2	Rat	membrane raft	located_in	IEA	UniProtKB-SubCell:SL-0370	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Gp2	Rat	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Gp2	Rat	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Gp2	Rat	side of membrane	located_in	IEA	UniProtKB-KW:KW-0336	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Gp2	Rat	zymogen granule membrane	located_in	IDA		633018	PMID:1999417	UniProt
Gp2	Rat	zymogen granule membrane	located_in	ISO	GP2 (Canis lupus familiaris)	1624291	PMID:2011597	RGD	PMID:2011597
Gp2	Rat	zymogen granule membrane	located_in	IEA	UniProtKB-SubCell:SL-0549	1600115	GO_REF:0000044	UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Gp2	Rat	antigen binding	enables	IEA	UniProtKB:P55259 and ensembl:ENSP00000304044	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Gp2	Rat	antigen binding	enables	ISO	Gp2 (Mus musculus)	1624291	PMID:19907495	RGD	PMID:19907495
Gp2	Rat	antigen binding	enables	ISO	GP2 (Homo sapiens)	1624291	PMID:19907495	RGD	PMID:19907495
Gp2	Rat	protein binding	enables	ISO	GP2 (Homo sapiens) and UniProtKB:P55259-4	1624291	UniProtKB:Q8N5M9 and PMID:32296183	RGD	PMID:32296183

#	Reference Title	Reference Citation
1.	Processing of the major pancreatic zymogen granule membrane protein, GP2.	Fritz BA, etal., Pancreas 2002 May;24(4):336-43.
2.	Nucleotide sequence encoding the major glycoprotein (GP2) of rat pancreatic secretory (zymogen) granule membranes.	Fukuoka S and Scheele G, Nucleic Acids Res 1990 Oct 11;18(19):5900.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Isolation of the cDNA encoding glycoprotein-2 (GP-2), the major zymogen granule membrane protein. Homology to uromodulin/Tamm-Horsfall protein.	Hoops TC and Rindler MJ, J Biol Chem 1991 Mar 5;266(7):4257-63.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:8352773	PMID:15313209	PMID:19907495	PMID:23533145

Gp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	183,228,395 - 183,243,954 (-)	NCBI		GRCr8
mRatBN7.2	1	173,797,057 - 173,812,619 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	173,797,057 - 173,812,619 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	182,107,960 - 182,123,570 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	189,294,066 - 189,309,672 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	182,029,288 - 182,044,898 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	189,166,735 - 189,182,306 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	189,166,399 - 189,182,306 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	196,108,647 - 196,127,738 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	177,709,931 - 177,725,490 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	177,849,176 - 177,864,736 (-)	NCBI
Celera	1	171,549,813 - 171,565,349 (-)	NCBI		Celera
Cytogenetic Map	1	q35	NCBI

GP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	20,309,574 - 20,327,513 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	20,309,574 - 20,327,808 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	20,320,896 - 20,338,835 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	20,229,312 - 20,246,336 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	20,229,312 - 20,246,336	NCBI
Celera	16	19,470,986 - 19,488,017 (-)	NCBI		Celera
Cytogenetic Map	16	p12.3	NCBI
HuRef	16	18,858,443 - 18,875,469 (-)	NCBI		HuRef
CHM1_1	16	20,409,707 - 20,426,730 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	20,240,526 - 20,258,466 (-)	NCBI		T2T-CHM13v2.0

Gp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	119,041,760 - 119,058,495 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	119,041,760 - 119,058,508 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	119,442,537 - 119,459,272 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	119,442,537 - 119,459,285 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	126,586,058 - 126,602,786 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	119,233,693 - 119,250,421 (-)	NCBI		MGSCv36	mm8
Celera	7	119,365,956 - 119,382,789 (-)	NCBI		Celera
Cytogenetic Map	7	F2	NCBI
cM Map	7	63.88	NCBI

Gp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	3,960,151 - 3,981,196 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	3,963,837 - 3,981,154 (-)	NCBI	ChiLan1.0	ChiLan1.0

GP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	21,572,575 - 21,590,816 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	26,094,232 - 26,112,477 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	17,985,586 - 18,003,831 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	20,406,346 - 20,424,576 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	20,407,989 - 20,423,199 (-)	Ensembl	panpan1.1		panPan2

GP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	25,010,847 - 25,027,339 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	25,010,847 - 25,027,339 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	26,373,696 - 26,390,188 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	25,164,976 - 25,181,468 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	25,164,840 - 25,181,468 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	24,965,814 - 24,982,316 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	24,861,208 - 24,877,708 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	25,248,882 - 25,265,376 (+)	NCBI		UU_Cfam_GSD_1.0

Gp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	117,718,768 - 117,730,626 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936501	5,816,629 - 5,828,470 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	25,497,292 - 25,517,096 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	25,496,533 - 25,518,210 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	26,272,613 - 26,293,686 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	18,599,038 - 18,615,895 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	18,596,144 - 18,615,401 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	11,291,073 - 11,307,837 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624782	3,612,126 - 3,637,219 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Gp2
172 total Variants

Assembly: Rnor_5.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain	Variant Page
1	196116271	196116272	A	G	snv	DOB/Oda (KyushuU), ZF (KyushuU), KFRS3B/Kyo (KyushuU)	View more Information

Predicted Target Of

	Summary Value
Count of predictions:	141
Count of miRNA genes:	113
Interacting mature miRNAs:	119
Transcripts:	ENSRNOT00000021249
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	167909849	212909849	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	123350408	182418476	Rat
2293673	Bss27	Bone structure and strength QTL 27	18.63	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	1	171629477	216629477	Rat
61326	Eae6	Experimental allergic encephalomyelitis QTL 6	5.3		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	172949660	181830018	Rat
2293677	Bss41	Bone structure and strength QTL 41	9.38	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	1	171629477	216629477	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	144267353	196383668	Rat
1549830	Bss1	Bone structure and strength QTL 1	4.8		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	172609619	217609619	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	151162512	201278233	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
2293689	Bss47	Bone structure and strength QTL 47	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	1	171629477	216629477	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	123556856	242907031	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	143506580	212458660	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169537671	214537671	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	151162512	201278233	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	155866514	200866514	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	117917486	196963478	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	151646613	196646613	Rat
2293693	Bss22	Bone structure and strength QTL 22	33.52	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	1	171629477	216629477	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
2300161	Bmd43	Bone mineral density QTL 43	8.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	158633083	203633083	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144017057	197814409	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	154561505	199561505	Rat
631214	Bw61	Body weight QTL61	3.4	0.0001	intramuscular adipose amount (VT:0010044)	intramuscular fat area (CMO:0001162)	1	173108781	218108781	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	149448574	221264292	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	115540693	185145286	Rat
2300174	Bmd42	Bone mineral density QTL 42	8.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	bone mineral density (CMO:0001226)	1	171629477	216629477	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	144267353	222987745	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	151162766	225824951	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
2293654	Bss30	Bone structure and strength QTL 30	32.65	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	1	171629477	216629477	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
2300187	Bmd41	Bone mineral density QTL 41	8.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
737974	Bp161	Blood pressure QTL 161		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	164747558	181133855	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	123350408	182418476	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
1358294	Bw37	Body weight QTL 37	5	0.000011	body mass (VT:0001259)	body weight (CMO:0000012)	1	171310381	216310381	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
61379	Bp44	Blood pressure QTL 44	19.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144267916	174133260	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	156677124	218753816	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
724550	Thym3	Thymus enlargement QTL 3	7.82	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
2312558	Glom17	Glomerulus QTL 17	3.9	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	166532971	191278129	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
71118	Thym1	Thymus enlargement QTL 1	10.17	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	164747424	209747424	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	136830018	181830018	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	169112897	197261052	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	169537671	214537671	Rat
2292222	Bp307	Blood pressure QTL 307	3.06	0.0014	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	213533942	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	243914901	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	201278233	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	156677124	201278233	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350408	181759564	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	123556856	196963478	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350581	201284552	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	156677124	176484451	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	123350408	182418476	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	201278233	Rat

RH141912

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	173,797,058 - 173,797,269 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	189,166,749 - 189,166,959	NCBI	Rnor6.0
Rnor_5.0	1	196,108,661 - 196,108,871	UniSTS	Rnor5.0
RGSC_v3.4	1	177,709,933 - 177,710,143	UniSTS	RGSC3.4
Celera	1	171,549,815 - 171,550,025	UniSTS
RH 3.4 Map	1	1381.4	UniSTS
Cytogenetic Map	1	q35	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	6	6	26	29	33	8	16	8	3	88	28	17	37	28	25


RefSeq Transcripts	NM_134418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M58716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X53935	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021249 ⟹ ENSRNOP00000021249

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	173,797,057 - 173,812,619 (-)	Ensembl
Rnor_6.0 Ensembl	1	189,166,747 - 189,182,306 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000092022 ⟹ ENSRNOP00000069047

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	173,797,284 - 173,812,619 (-)	Ensembl
Rnor_6.0 Ensembl	1	189,166,399 - 189,181,901 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103448 ⟹ ENSRNOP00000079152

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	173,797,057 - 173,812,619 (-)	Ensembl

RefSeq Acc Id:

NM_134418 ⟹ NP_599245

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	183,228,395 - 183,243,954 (-)	NCBI
mRatBN7.2	1	173,797,057 - 173,812,619 (-)	NCBI
Rnor_6.0	1	189,166,747 - 189,182,306 (-)	NCBI
Rnor_5.0	1	196,108,647 - 196,127,738 (-)	NCBI
RGSC_v3.4	1	177,709,931 - 177,725,490 (-)	RGD
Celera	1	171,549,813 - 171,565,349 (-)	RGD

Sequence:

show sequence

CACACTGGGCAGAGGAAGGAGGATACTCTGGCTTCTTTTATGATTTATGGAGGATCTGCAGGCTGCAGAATAACCAGCAAGCCTCACTTTATGAAAAGGATGGTGGCTTGTGACCTGCTGTGGCTGGC
TGCAGCCTCCTGCCTTCTGACACTGGTATTTCCATCTACAACACATCAAGGTTATGGAAACCCCAGAAACACCTCCAATGTGGACTTGGACTGTGGAGCCCCCGGCTCATCAAGTGCTGGCATCTGCT
TTGACCCCTGCCAGAATCACACCGTCCTGAATGATCCCTCCAGAAGCACAGAGAACACGGTGTCATCGGAGGAGTGTGATAGTCACCTGAGGGGCTGGTACCGCTTTGTGGGTGATGGGGGAGTGAAG
ATGCCAGAGACCTGTGTGAATGTGTACCGGTGCCACACCTATGCTCCCATGTGGCTGAGTGAATCACACCCCATCCTTGGAGATGGCATTGTCAACCGCACAGCCTGTGCCAACTGGAATGAAAATTG
TTGTTTCTGGAGTTCTGAGGTCCAGGTGAAGGCCTGTTTGGGAGAATCAGGAGAATATCACGTGTACAAGTTACAGGGCACCCCTGAATGCAGTCTGAGATACTGTACAGACCCCTCCACCGCACCGA
AAAAGTGTGAGATTGCTTGTCGTCCTGAGGAGGAATGTGTATTCCAAAATAACAGCTGGACCTGTGTCTGTAGGCAAGACCTCAATGTTTCTGACCCTCAGAGTTTGCAGCCTCTTCTGGACTGTGGG
GCTAATGAGATCAAGGTGAAGCTGGACAAGTGTTTGCTGGGAGGTCTGGGTTTCAAGGAGGACATCATCACCTACCTGAATGACCGGAACTGCAGAGGTACCATGAAAGATGAGCCCAACAACTGGGT
GTCCACGACCAGCCCTGTTGTGGCTAATGACTGTGGGAACATCCTGGAGAACAATGGGACCCATGCCATCTATAGAAACACCCTCTCCTTGGCCACTGATTTCATTATCAGGGACTTCCTTGTCAACG
TCAACTTCCAGTGTGCCTACCCTCTGGACATGAATGTCAGTCTCCAAACTGCACTCCAGCCCATCGTAAGTTCCCTGAATGTTGATGTGGGTGGAGCAGGAGAGTTCACTGTTACGATGGCACTCTTC
CAAGACCAAAGCTACACACACCCTTATGAAGGAAGCAAAGTGTTGCTTCCAGTGGAGAATATACTCTACGTGGGCGTCCTCTTGAATAGGGGTGATACCTCCAGGTTCAAACTGTTGCTGACCAACTG
CTATGCCACCCCTTCAGGAGACAGGAATGACATTGTGAAGTACTTCATCATCAGGAACAGATGCCCAAACCAACGTGATTCCACCATCAATGTGGAGGAGAATGGGGTGTCCTCGGAAAGCCGATTTT
CAGTGCAGATGTTCATGTTTGCTGGAAATTATGACCTAGTTTTCCTGCATTGTGAGGTTTACCTGTGTGACTCCACTACTGAACAGTGTCAACCATCTTGCTCTACAAGTCGACTTCGCAGTAGTGAA
CCAGCCATCGACTTAACTCGGGTTCTGGATATAGGACCCATCACTAAGAAAAGTGTTCAGAATCCTGATACCTCCAACGGGACTCCCCGAAGTACAGGGTTCCTGTTGGCCTGGCCCACGTTCTTCCT
GCCTGTCTTCCTGGCCTGGCTGTTCTGAGAGTCCAGCTGGGCACCTGGCCTTAAAGTTCTTCCCTCTGGCAATGGCTCATATCCACCGTTCAGTAGAACTGAATCCCTCTGTGAATCATGTGAACAGC
CCAGGAAATGCAATGTGTATTGATAACTCCTGGTTAGAGTTGTCCTGTTAGTGGGCAGAAAAGGGCAAATCCCATGATTCTTTCAAAATCTCTCTTGTCCTGACAGCCGATGTCATGAATACATGAA

hide sequence


Protein RefSeqs	NP_599245	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41268	(Get FASTA)	NCBI Sequence Viewer
	CAA37882	(Get FASTA)	NCBI Sequence Viewer
	EDM17673	(Get FASTA)	NCBI Sequence Viewer
	EDM17674	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021249
GenBank Protein	P19218	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_599245 ⟸ NM_134418
- Peptide Label:	precursor
- UniProtKB:	P19218 (UniProtKB/Swiss-Prot), A6I8K7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKRMVACDLLWLAAASCLLTLVFPSTTHQGYGNPRNTSNVDLDCGAPGSSSAGICFDPCQNHTVLNDPSRSTENTVSSEECDSHLRGWYRFVGDGGVKMPETCVNVYRCHTYAPMWLSESHPILGDGI VNRTACANWNENCCFWSSEVQVKACLGESGEYHVYKLQGTPECSLRYCTDPSTAPKKCEIACRPEEECVFQNNSWTCVCRQDLNVSDPQSLQPLLDCGANEIKVKLDKCLLGGLGFKEDIITYLNDRN CRGTMKDEPNNWVSTTSPVVANDCGNILENNGTHAIYRNTLSLATDFIIRDFLVNVNFQCAYPLDMNVSLQTALQPIVSSLNVDVGGAGEFTVTMALFQDQSYTHPYEGSKVLLPVENILYVGVLLNR GDTSRFKLLLTNCYATPSGDRNDIVKYFIIRNRCPNQRDSTINVEENGVSSESRFSVQMFMFAGNYDLVFLHCEVYLCDSTTEQCQPSCSTSRLRSSEPAIDLTRVLDIGPITKKSVQNPDTSNGTPR STGFLLAWPTFFLPVFLAWLF hide sequence

Ensembl Acc Id:

ENSRNOP00000069047 ⟸ ENSRNOT00000092022

Ensembl Acc Id:

ENSRNOP00000021249 ⟸ ENSRNOT00000021249

Ensembl Acc Id:

ENSRNOP00000079152 ⟸ ENSRNOT00000103448

Protein Domains

EGF-like ZP

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P19218-F1-model_v2	AlphaFold	P19218	1-530	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13690348

Promoter ID:

EPDNEW_R873

Type:

single initiation site

Name:

Gp2_1

Description:

glycoprotein 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	189,182,305 - 189,182,365	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-57655	BioCyc
Ensembl Genes	ENSRNOG00000015716	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000021249	ENTREZGENE
Gene3D-CATH	2.60.40.4100	UniProtKB/Swiss-Prot
	Zona pellucida, ZP-N domain	UniProtKB/Swiss-Prot
InterPro	ZP-C	UniProtKB/Swiss-Prot
	ZP_chr	UniProtKB/Swiss-Prot
	ZP_dom	UniProtKB/Swiss-Prot
	ZP_dom_CS	UniProtKB/Swiss-Prot
NCBI Gene	171459	ENTREZGENE
PANTHER	ENDOGLIN/TGF-BETA RECEPTOR TYPE III	UniProtKB/Swiss-Prot
	PANCREATIC SECRETORY GRANULE MEMBRANE MAJOR GLYCOPROTEIN GP2	UniProtKB/Swiss-Prot
Pfam	Zona_pellucida	UniProtKB/Swiss-Prot
PhenoGen	Gp2	PhenoGen
PRINTS	ZPELLUCIDA	UniProtKB/Swiss-Prot
PROSITE	ZP_1	UniProtKB/Swiss-Prot
	ZP_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000015716	RatGTEx
SMART	SM00241	UniProtKB/Swiss-Prot
UniProt	A0A0G2JUC6_RAT	UniProtKB/TrEMBL
	A0A8I6G4W5_RAT	UniProtKB/TrEMBL
	A6I8K7	ENTREZGENE, UniProtKB/TrEMBL
	F1M9X2_RAT	UniProtKB/TrEMBL
	GP2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-01-20	Gp2	glycoprotein 2	Gp2	glycoprotein 2 (zymogen granule membrane)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Gp2	glycoprotein 2 (zymogen granule membrane)		secretory (zymogen) granule membrane glycoprotein GP2	Name updated	1299863	APPROVED
2002-08-07	Gp2	secretory (zymogen) granule membrane glycoprotein GP2			Symbol and Name status set to provisional	70820	PROVISIONAL

Note Type	Note	Reference
gene_domains	contains eight potential N-glycosylation sites	633018
gene_homology	has 53% amino acid sequence identity to human uromodulin/Tamm-Horsfall protein (THP) over a 450 amino acid region	633018

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - CTD