Symbol:
Tmsb4x
Name:
thymosin beta 4, X-linked
RGD ID:
621622
Description:
Predicted to enable actin monomer binding activity; enzyme binding activity; and protein sequestering activity. Involved in osteoblast differentiation. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Orthologous to human TMSB4X (thymosin beta 4 X-linked); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
t beta 4; thymosin beta-4; thymosin, beta 4; thymosin, beta 4, X chromosome
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 30,761,611 - 30,763,612 (+) NCBI GRCr8 mRatBN7.2 X 27,144,666 - 27,146,667 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 10 47,260,023 - 47,260,175 (+) Ensembl mRatBN7.2 Ensembl mRatBN7.2 Ensembl X 27,128,610 - 27,146,667 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 28,217,413 - 28,219,416 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 31,619,373 - 31,621,374 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 27,832,051 - 27,834,054 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 28,593,405 - 28,617,267 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 28,593,405 - 28,595,395 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 28,985,080 - 28,987,070 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.1 5 59,582,271 - 59,582,388 (-) NCBI Celera X 27,555,904 - 27,557,894 (+) NCBI Celera Cytogenetic Map X q13 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Tmsb4x Rat (-)-alpha-phellandrene increases expression ISO TMSB4X (Homo sapiens) 6480464 alpha phellandrene results in increased expression of TMSB4X mRNA CTD PMID:25075043 Tmsb4x Rat (1->4)-beta-D-glucan multiple interactions ISO Tmsb4x (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMSB4X mRNA CTD PMID:36331819 Tmsb4x Rat 1,2-dichloroethane decreases expression ISO Tmsb4x (Mus musculus) 6480464 ethylene dichloride results in decreased expression of TMSB4X mRNA CTD PMID:28960355 Tmsb4x Rat 1,2-dimethylhydrazine decreases expression ISO Tmsb4x (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of TMSB4X mRNA CTD PMID:22206623 Tmsb4x Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of TMSB4X mRNA CTD PMID:17557909 Tmsb4x Rat 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of TMSB4X mRNA CTD PMID:26496021 Tmsb4x Rat 17beta-estradiol decreases expression ISO Tmsb4x (Mus musculus) 6480464 Estradiol results in decreased expression of TMSB4X mRNA CTD PMID:39298647 Tmsb4x Rat 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO TMSB4X (Homo sapiens) 6480464 bicalutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of TMSB4X mRNA] CTD PMID:17916567 Tmsb4x Rat 17beta-hydroxy-5alpha-androstan-3-one decreases expression ISO TMSB4X (Homo sapiens) 6480464 Dihydrotestosterone results in decreased expression of TMSB4X mRNA CTD PMID:17916567 Tmsb4x Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of TMSB4X mRNA CTD PMID:34747641 Tmsb4x Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Tmsb4x (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Tmsb4x Rat 2,6-dimethoxyphenol multiple interactions ISO TMSB4X (Homo sapiens) 6480464 [Furaldehyde co-treated with pyrogallol 1 more ... CTD PMID:38598786 Tmsb4x Rat 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one decreases expression ISO Tmsb4x (Mus musculus) 6480464 Itraconazole results in decreased expression of TMSB4X mRNA CTD PMID:31099283 Tmsb4x Rat 4,4'-sulfonyldiphenol decreases expression ISO Tmsb4x (Mus musculus) 6480464 bisphenol S results in decreased expression of TMSB4X mRNA CTD PMID:39298647 Tmsb4x Rat 4-hydroxyphenyl retinamide increases expression ISO Tmsb4x (Mus musculus) 6480464 Fenretinide results in increased expression of TMSB4X mRNA CTD PMID:28973697 Tmsb4x Rat 4-hydroxyphenyl retinamide decreases expression ISO Tmsb4x (Mus musculus) 6480464 Fenretinide results in decreased expression of TMSB4X mRNA CTD PMID:28973697 Tmsb4x Rat 5-aza-2'-deoxycytidine affects methylation ISO TMSB4X (Homo sapiens) 6480464 Decitabine affects the methylation of TMSB4X gene CTD PMID:17630775 Tmsb4x Rat 5-fluorouracil increases expression ISO TMSB4X (Homo sapiens) 6480464 Fluorouracil results in increased expression of TMSB4X mRNA CTD PMID:15152939 Tmsb4x Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of TMSB4X mRNA CTD PMID:24780913 and PMID:30047161 Tmsb4x Rat acetylsalicylic acid increases expression ISO TMSB4X (Homo sapiens) 6480464 Aspirin results in increased expression of TMSB4X mRNA CTD PMID:15928584 Tmsb4x Rat aflatoxin B1 decreases expression ISO Tmsb4x (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of TMSB4X mRNA CTD PMID:19770486 Tmsb4x Rat aldehydo-D-glucose increases expression ISO Tmsb4x (Mus musculus) 6480464 Glucose results in increased expression of TMSB4X mRNA CTD PMID:17178593 Tmsb4x Rat all-trans-4-oxoretinoic acid increases expression ISO TMSB4X (Homo sapiens) 6480464 4-oxoretinoic acid results in increased expression of TMSB4X mRNA CTD PMID:15982314 Tmsb4x Rat all-trans-retinoic acid increases expression ISO TMSB4X (Homo sapiens) 6480464 Tretinoin metabolite results in increased expression of TMSB4X mRNA and Tretinoin results in increased expression of TMSB4X mRNA CTD PMID:15982314 more ... Tmsb4x Rat all-trans-retinoic acid increases acetylation ISO TMSB4X (Homo sapiens) 6480464 Tretinoin results in increased acetylation of TMSB4X protein CTD PMID:28053092 Tmsb4x Rat all-trans-retinoic acid decreases expression ISO Tmsb4x (Mus musculus) 6480464 Tretinoin results in decreased expression of TMSB4X mRNA CTD PMID:16604517 Tmsb4x Rat alpha-phellandrene increases expression ISO TMSB4X (Homo sapiens) 6480464 alpha phellandrene results in increased expression of TMSB4X mRNA CTD PMID:25075043 Tmsb4x Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of TMSB4X mRNA CTD PMID:30047161 Tmsb4x Rat aristolochic acid A decreases expression ISO TMSB4X (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of TMSB4X mRNA CTD PMID:33212167 Tmsb4x Rat atrazine multiple interactions ISO TMSB4X (Homo sapiens) 6480464 [Atrazine co-treated with Arsenates] results in increased expression of TMSB4X mRNA CTD PMID:18585445 Tmsb4x Rat benzo[a]pyrene decreases expression ISO Tmsb4x (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of TMSB4X mRNA CTD PMID:19770486 Tmsb4x Rat benzo[a]pyrene increases methylation ISO TMSB4X (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of TMSB4X promoter CTD PMID:27901495 Tmsb4x Rat benzo[b]fluoranthene increases expression ISO Tmsb4x (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of TMSB4X mRNA CTD PMID:26377693 Tmsb4x Rat beryllium sulfate increases expression ISO TMSB4X (Homo sapiens) 6480464 beryllium sulfate results in increased expression of TMSB4X mRNA CTD PMID:16314022 Tmsb4x Rat bicalutamide multiple interactions ISO TMSB4X (Homo sapiens) 6480464 bicalutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of TMSB4X mRNA] CTD PMID:17916567 Tmsb4x Rat bicalutamide increases expression ISO TMSB4X (Homo sapiens) 6480464 bicalutamide results in increased expression of TMSB4X mRNA CTD PMID:17916567 Tmsb4x Rat bis(2-ethylhexyl) phthalate affects expression ISO Tmsb4x (Mus musculus) 6480464 Diethylhexyl Phthalate affects the expression of TMSB4X mRNA CTD PMID:33754040 Tmsb4x Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of TMSB4X mRNA CTD PMID:26496021 Tmsb4x Rat bisphenol A decreases expression ISO Tmsb4x (Mus musculus) 6480464 bisphenol A results in decreased expression of TMSB4X protein CTD PMID:35999755 Tmsb4x Rat bisphenol A increases expression ISO Tmsb4x (Mus musculus) 6480464 bisphenol A results in increased expression of TMSB4X mRNA CTD PMID:32156529 and PMID:33221593 Tmsb4x Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of TMSB4X mRNA CTD PMID:30903817 Tmsb4x Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TMSB4X mRNA CTD PMID:30816183 more ... Tmsb4x Rat bisphenol A increases expression ISO TMSB4X (Homo sapiens) 6480464 bisphenol A results in increased expression of TMSB4X mRNA and bisphenol A results in increased expression of TMSB4X protein CTD PMID:25047013 and PMID:37567409 Tmsb4x Rat Bisphenol B increases expression ISO TMSB4X (Homo sapiens) 6480464 bisphenol B results in increased expression of TMSB4X protein CTD PMID:34186270 Tmsb4x Rat bisphenol F increases expression ISO TMSB4X (Homo sapiens) 6480464 bisphenol F results in increased expression of TMSB4X protein CTD PMID:34186270 Tmsb4x Rat buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of TMSB4X mRNA CTD PMID:24136188 Tmsb4x Rat cadmium acetate increases expression ISO TMSB4X (Homo sapiens) 6480464 cadmium acetate results in increased expression of TMSB4X mRNA CTD PMID:12965115 Tmsb4x Rat cadmium atom increases expression ISO TMSB4X (Homo sapiens) 6480464 Cadmium results in increased expression of TMSB4X mRNA CTD PMID:24376830 Tmsb4x Rat cadmium dichloride decreases expression ISO TMSB4X (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of TMSB4X mRNA CTD PMID:12760830 Tmsb4x Rat cadmium dichloride increases expression ISO TMSB4X (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of TMSB4X mRNA CTD PMID:38568856 Tmsb4x Rat carbon nanotube decreases expression ISO Tmsb4x (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 Tmsb4x Rat carnosic acid decreases expression ISO Tmsb4x (Mus musculus) 6480464 salvin results in decreased expression of TMSB4X protein CTD PMID:35926579 Tmsb4x Rat chloropicrin increases expression ISO TMSB4X (Homo sapiens) 6480464 chloropicrin results in increased expression of TMSB4X mRNA CTD PMID:26352163 Tmsb4x Rat choline multiple interactions ISO Tmsb4x (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TMSB4X mRNA CTD PMID:20938992 Tmsb4x Rat cisplatin increases expression ISO Tmsb4x (Mus musculus) 6480464 Cisplatin results in increased expression of TMSB4X mRNA CTD PMID:21151649 Tmsb4x Rat clofibrate increases expression ISO Tmsb4x (Mus musculus) 6480464 Clofibrate results in increased expression of TMSB4X mRNA CTD PMID:17585979 Tmsb4x Rat clofibric acid affects expression EXP 6480464 Clofibric Acid affects the expression of TMSB4X mRNA CTD PMID:17602206 Tmsb4x Rat cobalt dichloride decreases expression ISO TMSB4X (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of TMSB4X mRNA CTD PMID:19376846 Tmsb4x Rat CU-O LINKAGE decreases expression ISO TMSB4X (Homo sapiens) 6480464 cupric oxide results in decreased expression of TMSB4X mRNA CTD PMID:22077320 Tmsb4x Rat D-glucose increases expression ISO Tmsb4x (Mus musculus) 6480464 Glucose results in increased expression of TMSB4X mRNA CTD PMID:17178593 Tmsb4x Rat dexamethasone increases expression ISO TMSB4X (Homo sapiens) 6480464 Dexamethasone results in increased expression of TMSB4X mRNA CTD PMID:25047013 Tmsb4x Rat dextran sulfate decreases expression ISO Tmsb4x (Mus musculus) 6480464 Dextran Sulfate results in decreased expression of TMSB4X protein CTD PMID:35999755 Tmsb4x Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of TMSB4X mRNA CTD PMID:17379624 and PMID:21266533 Tmsb4x Rat dibutyl phthalate increases expression ISO Tmsb4x (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of TMSB4X mRNA CTD PMID:21266533 Tmsb4x Rat dicrotophos decreases expression ISO TMSB4X (Homo sapiens) 6480464 dicrotophos results in decreased expression of TMSB4X mRNA CTD PMID:28302478 Tmsb4x Rat dioxygen affects expression ISO Tmsb4x (Mus musculus) 6480464 Oxygen deficiency affects the expression of TMSB4X mRNA CTD PMID:17193925 Tmsb4x Rat diuron decreases expression ISO TMSB4X (Homo sapiens) 6480464 Diuron results in decreased expression of TMSB4X mRNA CTD PMID:35967413 Tmsb4x Rat doxorubicin decreases response to substance ISO TMSB4X (Homo sapiens) 6480464 TMSB4X protein results in decreased susceptibility to Doxorubicin CTD PMID:16364925 Tmsb4x Rat doxorubicin increases expression ISO TMSB4X (Homo sapiens) 6480464 Doxorubicin results in increased expression of TMSB4X mRNA CTD PMID:29803840 Tmsb4x Rat doxorubicin multiple interactions ISO TMSB4X (Homo sapiens) 6480464 TMSB4X protein inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein] and TMSB4X protein inhibits the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP9 protein] CTD PMID:16364925 Tmsb4x Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of TMSB4X mRNA CTD PMID:29391264 Tmsb4x Rat epoxiconazole increases expression ISO Tmsb4x (Mus musculus) 6480464 epoxiconazole results in increased expression of TMSB4X mRNA CTD PMID:35436446 Tmsb4x Rat ethanol affects splicing ISO Tmsb4x (Mus musculus) 6480464 Ethanol affects the splicing of TMSB4X mRNA CTD PMID:30319688 Tmsb4x Rat etoposide decreases response to substance ISO TMSB4X (Homo sapiens) 6480464 TMSB4X protein results in decreased susceptibility to Etoposide CTD PMID:16364925 Tmsb4x Rat etoposide multiple interactions ISO TMSB4X (Homo sapiens) 6480464 TMSB4X protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein] and TMSB4X protein inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein] CTD PMID:16364925 Tmsb4x Rat fenthion increases expression ISO Tmsb4x (Mus musculus) 6480464 Fenthion results in increased expression of TMSB4X mRNA CTD PMID:34813904 Tmsb4x Rat flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of TMSB4X mRNA CTD PMID:24136188 Tmsb4x Rat folic acid multiple interactions ISO Tmsb4x (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TMSB4X mRNA CTD PMID:20938992 Tmsb4x Rat folic acid decreases expression ISO Tmsb4x (Mus musculus) 6480464 Folic Acid results in decreased expression of TMSB4X mRNA CTD PMID:25629700 Tmsb4x Rat furfural multiple interactions ISO TMSB4X (Homo sapiens) 6480464 [Furaldehyde co-treated with pyrogallol 1 more ... CTD PMID:38598786 Tmsb4x Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of TMSB4X mRNA CTD PMID:22061828 Tmsb4x Rat glucose increases expression ISO Tmsb4x (Mus musculus) 6480464 Glucose results in increased expression of TMSB4X mRNA CTD PMID:17178593 Tmsb4x Rat griseofulvin affects expression ISO Tmsb4x (Mus musculus) 6480464 Griseofulvin affects the expression of TMSB4X mRNA CTD PMID:12735108 Tmsb4x Rat indometacin increases expression ISO TMSB4X (Homo sapiens) 6480464 Indomethacin results in increased expression of TMSB4X mRNA CTD PMID:15292456 Tmsb4x Rat irinotecan multiple interactions ISO Tmsb4x (Mus musculus) 6480464 [PHY 906 co-treated with Irinotecan] affects the expression of TMSB4X mRNA CTD PMID:32812032 Tmsb4x Rat iron dichloride increases expression ISO TMSB4X (Homo sapiens) 6480464 ferrous chloride results in increased expression of TMSB4X mRNA CTD PMID:35984750 Tmsb4x Rat isoprenaline decreases expression ISO Tmsb4x (Mus musculus) 6480464 Isoproterenol results in decreased expression of TMSB4X mRNA CTD PMID:21335049 Tmsb4x Rat itraconazole decreases expression ISO Tmsb4x (Mus musculus) 6480464 Itraconazole results in decreased expression of TMSB4X mRNA CTD PMID:31099283 Tmsb4x Rat ivermectin decreases expression ISO TMSB4X (Homo sapiens) 6480464 Ivermectin results in decreased expression of TMSB4X protein CTD PMID:32959892 Tmsb4x Rat ketoconazole decreases expression ISO Tmsb4x (Mus musculus) 6480464 Ketoconazole results in decreased expression of TMSB4X mRNA CTD PMID:31099283 Tmsb4x Rat L-methionine multiple interactions ISO Tmsb4x (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TMSB4X mRNA CTD PMID:20938992 Tmsb4x Rat lipopolysaccharide multiple interactions ISO TMSB4X (Homo sapiens) 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of TMSB4X mRNA CTD PMID:35877022 Tmsb4x Rat methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of TMSB4X mRNA CTD PMID:30467583 Tmsb4x Rat methidathion increases expression ISO Tmsb4x (Mus musculus) 6480464 methidathion results in increased expression of TMSB4X mRNA CTD PMID:34813904 Tmsb4x Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of TMSB4X mRNA CTD PMID:30047161 Tmsb4x Rat microcystin-LR increases expression ISO Tmsb4x (Mus musculus) 6480464 cyanoginosin LR results in increased expression of TMSB4X mRNA CTD PMID:17654400 Tmsb4x Rat Muraglitazar decreases expression EXP 6480464 muraglitazar results in decreased expression of TMSB4X mRNA CTD PMID:21515302 Tmsb4x Rat N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO Tmsb4x (Mus musculus) 6480464 [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TMSB4X mRNA CTD PMID:19840844 Tmsb4x Rat N-nitrosodiethylamine increases expression ISO Tmsb4x (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of TMSB4X mRNA CTD PMID:17942915 Tmsb4x Rat N-nitrosodiethylamine multiple interactions ISO Tmsb4x (Mus musculus) 6480464 MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TMSB4X mRNA] CTD PMID:17942915 Tmsb4x Rat nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of TMSB4X mRNA CTD PMID:24136188 Tmsb4x Rat nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of TMSB4X mRNA CTD PMID:24136188 Tmsb4x Rat nitrates multiple interactions ISO Tmsb4x (Mus musculus) 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of TMSB4X mRNA CTD PMID:35964746 Tmsb4x Rat okadaic acid multiple interactions ISO Tmsb4x (Mus musculus) 6480464 [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TMSB4X mRNA CTD PMID:19840844 Tmsb4x Rat ozone multiple interactions ISO Tmsb4x (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of TMSB4X mRNA CTD PMID:34911549 Tmsb4x Rat p-toluidine decreases expression EXP 6480464 4-toluidine results in decreased expression of TMSB4X mRNA CTD PMID:27638505 Tmsb4x Rat paracetamol affects expression ISO Tmsb4x (Mus musculus) 6480464 Acetaminophen affects the expression of TMSB4X mRNA CTD PMID:17562736 Tmsb4x Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of TMSB4X mRNA CTD PMID:33387578 Tmsb4x Rat paracetamol decreases expression ISO Tmsb4x (Mus musculus) 6480464 Acetaminophen results in decreased expression of TMSB4X mRNA CTD PMID:17585979 Tmsb4x Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Tmsb4x (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMSB4X mRNA CTD PMID:36331819 Tmsb4x Rat perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of TMSB4X mRNA and perfluorooctanoic acid results in decreased expression of TMSB4X protein CTD PMID:19162173 and PMID:34958885 Tmsb4x Rat pirinixic acid decreases expression ISO Tmsb4x (Mus musculus) 6480464 pirinixic acid results in decreased expression of TMSB4X mRNA CTD PMID:18445702 Tmsb4x Rat pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of TMSB4X mRNA CTD PMID:19162173 and PMID:22484513 Tmsb4x Rat Rutecarpine decreases expression ISO TMSB4X (Homo sapiens) 6480464 rutecarpine results in decreased expression of TMSB4X mRNA CTD PMID:34955744 Tmsb4x Rat sodium arsenite increases expression ISO TMSB4X (Homo sapiens) 6480464 sodium arsenite results in increased expression of TMSB4X mRNA CTD PMID:12760830 and PMID:38568856 Tmsb4x Rat sodium arsenite increases expression ISO Tmsb4x (Mus musculus) 6480464 sodium arsenite results in increased expression of TMSB4X protein CTD PMID:29044176 Tmsb4x Rat sodium chloride multiple interactions ISO TMSB4X (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of and affects the localization of TMSB4X protein more ... CTD PMID:38598786 Tmsb4x Rat sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of TMSB4X mRNA CTD PMID:30047161 Tmsb4x Rat sulindac sulfide decreases expression ISO TMSB4X (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of TMSB4X mRNA CTD PMID:15292456 Tmsb4x Rat sunitinib decreases expression ISO TMSB4X (Homo sapiens) 6480464 Sunitinib results in decreased expression of TMSB4X mRNA CTD PMID:31533062 Tmsb4x Rat tamoxifen increases expression ISO Tmsb4x (Mus musculus) 6480464 Tamoxifen results in increased expression of TMSB4X mRNA CTD PMID:17555576 Tmsb4x Rat tetrachloromethane increases expression ISO Tmsb4x (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of TMSB4X mRNA CTD PMID:29987408 Tmsb4x Rat tetrachloromethane affects expression ISO Tmsb4x (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of TMSB4X mRNA CTD PMID:31919559 Tmsb4x Rat thiram increases expression ISO TMSB4X (Homo sapiens) 6480464 Thiram results in increased expression of TMSB4X mRNA CTD PMID:38568856 Tmsb4x Rat titanium dioxide decreases expression ISO Tmsb4x (Mus musculus) 6480464 titanium dioxide results in decreased expression of TMSB4X mRNA CTD PMID:29264374 Tmsb4x Rat tolcapone decreases expression EXP 6480464 tolcapone results in decreased expression of TMSB4X mRNA CTD PMID:24136188 Tmsb4x Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of TMSB4X mRNA CTD PMID:33387578 Tmsb4x Rat troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of TMSB4X mRNA CTD PMID:21515302 Tmsb4x Rat tunicamycin increases expression ISO TMSB4X (Homo sapiens) 6480464 Tunicamycin results in increased expression of TMSB4X mRNA CTD PMID:29453283 Tmsb4x Rat valproic acid increases methylation ISO TMSB4X (Homo sapiens) 6480464 Valproic Acid results in increased methylation of TMSB4X gene CTD PMID:29154799 Tmsb4x Rat vancomycin decreases expression ISO Tmsb4x (Mus musculus) 6480464 Vancomycin results in decreased expression of TMSB4X mRNA CTD PMID:18930951 Tmsb4x Rat zoledronic acid decreases expression ISO TMSB4X (Homo sapiens) 6480464 zoledronic acid results in decreased expression of TMSB4X protein CTD PMID:28871336
(-)-alpha-phellandrene (ISO) (1->4)-beta-D-glucan (ISO) 1,2-dichloroethane (ISO) 1,2-dimethylhydrazine (ISO) 17alpha-ethynylestradiol (EXP) 17beta-estradiol (EXP,ISO) 17beta-hydroxy-5alpha-androstan-3-one (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 2,6-dimethoxyphenol (ISO) 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one (ISO) 4,4'-sulfonyldiphenol (ISO) 4-hydroxyphenyl retinamide (ISO) 5-aza-2'-deoxycytidine (ISO) 5-fluorouracil (ISO) 6-propyl-2-thiouracil (EXP) acetylsalicylic acid (ISO) aflatoxin B1 (ISO) aldehydo-D-glucose (ISO) all-trans-4-oxoretinoic acid (ISO) all-trans-retinoic acid (ISO) alpha-phellandrene (ISO) amitrole (EXP) aristolochic acid A (ISO) atrazine (ISO) benzo[a]pyrene (ISO) benzo[b]fluoranthene (ISO) beryllium sulfate (ISO) bicalutamide (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) Bisphenol B (ISO) bisphenol F (ISO) buspirone (EXP) cadmium acetate (ISO) cadmium atom (ISO) cadmium dichloride (ISO) carbon nanotube (ISO) carnosic acid (ISO) chloropicrin (ISO) choline (ISO) cisplatin (ISO) clofibrate (ISO) clofibric acid (EXP) cobalt dichloride (ISO) CU-O LINKAGE (ISO) D-glucose (ISO) dexamethasone (ISO) dextran sulfate (ISO) dibutyl phthalate (EXP,ISO) dicrotophos (ISO) dioxygen (ISO) diuron (ISO) doxorubicin (ISO) endosulfan (EXP) epoxiconazole (ISO) ethanol (ISO) etoposide (ISO) fenthion (ISO) flutamide (EXP) folic acid (ISO) furfural (ISO) gentamycin (EXP) glucose (ISO) griseofulvin (ISO) indometacin (ISO) irinotecan (ISO) iron dichloride (ISO) isoprenaline (ISO) itraconazole (ISO) ivermectin (ISO) ketoconazole (ISO) L-methionine (ISO) lipopolysaccharide (ISO) methapyrilene (EXP) methidathion (ISO) methimazole (EXP) microcystin-LR (ISO) Muraglitazar (EXP) N-methyl-N'-nitro-N-nitrosoguanidine (ISO) N-nitrosodiethylamine (ISO) nefazodone (EXP) nimesulide (EXP) nitrates (ISO) okadaic acid (ISO) ozone (ISO) p-toluidine (EXP) paracetamol (EXP,ISO) perfluorooctane-1-sulfonic acid (ISO) perfluorooctanoic acid (EXP) pirinixic acid (EXP,ISO) Rutecarpine (ISO) sodium arsenite (ISO) sodium chloride (ISO) sulfadimethoxine (EXP) sulindac sulfide (ISO) sunitinib (ISO) tamoxifen (ISO) tetrachloromethane (ISO) thiram (ISO) titanium dioxide (ISO) tolcapone (EXP) trichloroethene (EXP) troglitazone (EXP) tunicamycin (ISO) valproic acid (ISO) vancomycin (ISO) zoledronic acid (ISO)
1.
Differential expression of thymosins beta(4) and beta(10) during rat cerebellum postnatal development.
Anadon R, etal., Brain Res 2001 Mar 16;894(2):255-65.
2.
Thymosin beta 4 is expressed in ROS 17/2.8 osteosarcoma cells in a regulated manner.
Atkinson MJ, etal., Mol Endocrinol 1990 Jan;4(1):69-74.
3.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.
Sequence of a cloned 523-bp cDNA for thymosin beta 4.
Goodall GJ, etal., Arch Biochem Biophys 1985 Jan;236(1):445-7.
5.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
6.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.
GOA pipeline
RGD automated data pipeline
8.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
9.
Cloning and sequence analysis of cDNA for rat spleen thymosin beta 4.
Wodnar-Filipowicz A, etal., Proc Natl Acad Sci U S A 1984 Apr;81(8):2295-7.
Tmsb4x Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 30,761,611 - 30,763,612 (+) NCBI GRCr8 mRatBN7.2 X 27,144,666 - 27,146,667 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 10 47,260,023 - 47,260,175 (+) Ensembl mRatBN7.2 Ensembl mRatBN7.2 Ensembl X 27,128,610 - 27,146,667 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 28,217,413 - 28,219,416 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 31,619,373 - 31,621,374 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 27,832,051 - 27,834,054 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 28,593,405 - 28,617,267 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 28,593,405 - 28,595,395 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 28,985,080 - 28,987,070 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.1 5 59,582,271 - 59,582,388 (-) NCBI Celera X 27,555,904 - 27,557,894 (+) NCBI Celera Cytogenetic Map X q13 NCBI
TMSB4X Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 X 12,975,110 - 12,977,223 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl X 12,975,110 - 12,977,227 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 X 12,993,229 - 12,995,342 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 X 12,903,148 - 12,905,267 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 X 12,752,883 - 12,755,002 NCBI Celera X 17,110,896 - 17,113,015 (+) NCBI Celera Cytogenetic Map X p22.2 NCBI HuRef X 10,756,223 - 10,758,343 (+) NCBI HuRef CHM1_1 X 13,023,770 - 13,025,890 (+) NCBI CHM1_1 T2T-CHM13v2.0 X 12,556,537 - 12,558,650 (+) NCBI T2T-CHM13v2.0
Tmsb4x Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 X 165,990,089 - 165,996,475 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl X 165,990,089 - 165,992,311 (-) Ensembl GRCm39 Ensembl GRCm38 X 167,207,093 - 167,213,479 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl X 167,207,093 - 167,209,315 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 X 163,645,026 - 163,647,150 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 X 144,389,562 - 144,391,688 (-) NCBI MGSCv36 mm8 MGSCv36 X 162,551,199 - 162,553,323 (-) NCBI MGSCv36 mm8 Celera X 150,380,762 - 150,382,939 (-) NCBI Celera Cytogenetic Map X F5 NCBI cM Map X 78.28 NCBI
Tmsb4x Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955544 266,397 - 268,447 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955544 266,397 - 268,447 (-) NCBI ChiLan1.0 ChiLan1.0
TMSB4X Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 X 14,759,411 - 14,761,586 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 X 14,763,035 - 14,765,252 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 X 5,587,242 - 5,589,417 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3
LOC100683370 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 1 21,127,694 - 21,128,346 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 1 22,118,894 - 22,119,534 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 1 21,020,853 - 21,021,492 (-) NCBI ROS_Cfam_1.0 UMICH_Zoey_3.1 1 21,077,166 - 21,077,806 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 1 20,969,395 - 20,970,035 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 1 21,240,994 - 21,241,634 (-) NCBI UU_Cfam_GSD_1.0
Tmsb4x Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 X 2,668,453 - 2,670,610 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936470 2,668,016 - 2,670,770 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936470 2,668,525 - 2,670,611 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
TMSB4X Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl X 9,650,179 - 9,651,661 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 X 9,649,516 - 9,651,662 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 X 10,549,221 - 10,551,375 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
TMSB4X
Tmsb4x
.
Predicted Target Of
Count of predictions: 194 Count of miRNA genes: 131 Interacting mature miRNAs: 149 Transcripts: ENSRNOT00000071708 Prediction methods: Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan Result types: miRGate_prediction
1598873 Memor2 Memory QTL 2 2.5 exploratory behavior trait (VT:0010471) average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674) X 20990947 41052531 Rat 70165 Bp64 Blood pressure QTL 64 5.2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) X 1448129 31706553 Rat 1298071 Edpm12 Estrogen-dependent pituitary mass QTL 12 3.2 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) X 2927898 47927898 Rat 2290375 Gluco34 Glucose level QTL 34 2.75 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) X 20990947 41203591 Rat 731181 Uae27 Urinary albumin excretion QTL 27 2.7 0.0059 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) X 1 43491017 Rat 61430 Cia18 Collagen induced arthritis QTL 18 3.1 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) X 14843113 120568734 Rat 10755455 Coatc13 Coat color QTL 13 0 coat/hair pigmentation trait (VT:0010463) pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812) 7 4406000 49406000 Rat 631666 Iddm5 Insulin dependent diabetes mellitus QTL 5 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) X 4494549 49494549 Rat 71116 Niddm16 Non-insulin dependent diabetes mellitus QTL 16 7.81 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) X 15297802 60297802 Rat
TMSB4X
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 X 27,146,300 - 27,146,518 (+) MAPPER mRatBN7.2 Rnor_6.0 X 28,595,029 - 28,595,246 NCBI Rnor6.0 Rnor_5.0 X 28,986,704 - 28,986,921 UniSTS Rnor5.0 Celera X 27,557,528 - 27,557,745 UniSTS Cytogenetic Map 5 q22 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
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Ensembl Acc Id:
ENSRNOT00000071708 ⟹ ENSRNOP00000066062
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 27,128,610 - 27,146,667 (+) Ensembl Rnor_6.0 Ensembl X 28,593,405 - 28,595,395 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000072548 ⟹ ENSRNOP00000065577
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 10 47,260,023 - 47,260,175 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000102572 ⟹ ENSRNOP00000097796
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 27,144,555 - 27,146,667 (+) Ensembl
RefSeq Acc Id:
NM_031136 ⟹ NP_112398
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 30,761,611 - 30,763,612 (+) NCBI mRatBN7.2 X 27,144,666 - 27,146,667 (+) NCBI Rnor_6.0 X 28,593,405 - 28,617,267 (+) NCBI Rnor_5.0 X 28,985,080 - 28,987,070 (+) NCBI Celera X 27,555,904 - 27,557,894 (+) NCBI
Sequence:
GCGGCCTCTGAGCAGATCGTCTCTCCTTGTTCGCCCAGCTCGCTCAGCTCCTTCCAGCAACCATGTCTGACAAACCCGATATGGCTGAGATCGAGAAATTCGATAAGTCGAAGTTGAAGAAGACAGAA
hide sequence
RefSeq Acc Id:
NP_112398 ⟸ NM_031136
- UniProtKB:
Q0P5V6 (UniProtKB/Swiss-Prot), P62329 (UniProtKB/Swiss-Prot), M0R7Y9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id:
ENSRNOP00000066062 ⟸ ENSRNOT00000071708
Ensembl Acc Id:
ENSRNOP00000097796 ⟸ ENSRNOT00000102572
Ensembl Acc Id:
ENSRNOP00000065577 ⟸ ENSRNOT00000072548
RGD ID: 13701786 Promoter ID: EPDNEW_R12309 Type: single initiation site Name: Tmsb4x_1 Description: thymosin beta 4, X-linked SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 X 28,593,397 - 28,593,457 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2014-12-31
Tmsb4x
thymosin beta 4, X-linked
Tmsb4x
thymosin, beta 4, X chromosome
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2013-08-02
Tmsb4x
thymosin, beta 4, X chromosome
Tmsb4x
thymosin beta 4, X-linked
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2008-11-14
Tmsb4x
thymosin beta 4, X-linked
Tmsb4x
thymosin, beta 4, X chromosome
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2008-02-25
Tmsb4x
thymosin, beta 4, X chromosome
Tmsb4x
thymosin, beta 4
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2005-01-20
Tmsb4x
thymosin, beta 4
thymosin beta-4
Name updated
1299863 APPROVED
2002-08-07
Tmsb4x
thymosin beta-4
Symbol and Name status set to provisional
70820 PROVISIONAL
Note Type
Note
Reference
gene_product
member of the beta-thymosin family of actin monomer-sequestering proteins
737835
