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Gene: TMSB4X (thymosin beta 4 X-linked) Homo sapiens
Symbol: TMSB4X
Name: thymosin beta 4 X-linked
Description: Exhibits actin monomer binding activity and enzyme binding activity. Involved in several processes, including negative regulation of NIK/NF-kappaB signaling; positive regulation of endothelial cell migration; and regulation of nucleobase-containing compound metabolic process. Localizes to the cytosol and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FX; prothymosin beta-4; PTMB4; t beta-4; TB4X; thymosin beta 4, X-linked; thymosin beta-4; thymosin, beta 4, X chromosome; thymosin, beta 4, X-linked; TMSB4
Mus musculus (house mouse) : Tmsb4x (thymosin, beta 4, X chromosome)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tmsb4x (thymosin beta 4, X-linked)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmsb4x (thymosin beta 4 X-linked)
Canis lupus familiaris (dog) : LOC100683370 (thymosin beta-4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmsb4x (thymosin beta 4 X-linked)
Sus scrofa (pig) : TMSB4X (thymosin beta 4 X-linked)
Chlorocebus sabaeus (green monkey) : TMSB4X (thymosin beta 4 X-linked)
Heterocephalus glaber (naked mole-rat) : Tmsb4x (thymosin beta 4 X-linked)
more info ...
Related Pseudogenes: TMSB4XP1   TMSB4XP2   TMSB4XP3   TMSB4XP4   TMSB4XP5   TMSB4XP6   TMSB4XP7   TMSB4XP8  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX12,975,110 - 12,977,227 (+)Ensembl
GRCh38X12,975,110 - 12,977,223 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X12,993,226 - 12,995,346 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X12,903,148 - 12,905,267 (+)NCBINCBI36hg18NCBI36
Build 34X12,752,883 - 12,755,002NCBI
CeleraX17,110,896 - 17,113,015 (+)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX10,756,223 - 10,758,343 (+)NCBIHuRef
CHM1_1X13,023,770 - 13,025,890 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TMSB4X
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736781
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.