Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Abtb2 | Rat | (-)-demecolcine | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of ABTB2 mRNA | CTD | PMID:23649840 | Abtb2 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Abtb2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ABTB2 mRNA | CTD | PMID:36331819 | Abtb2 | Rat | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of ABTB2 mRNA | CTD | PMID:30723492 | Abtb2 | Rat | 17beta-estradiol | multiple interactions | ISO | ABTB2 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of ABTB2 mRNA | CTD | PMID:30165855 | Abtb2 | Rat | 17beta-estradiol | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Estradiol results in increased expression of ABTB2 mRNA | CTD | PMID:31614463 | Abtb2 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Abtb2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ABTB2 mRNA | CTD | PMID:21215274 | Abtb2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ABTB2 mRNA | CTD | PMID:33387578 | Abtb2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Abtb2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ABTB2 mRNA | CTD | PMID:26290441 | Abtb2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Abtb2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ABTB2 mRNA | CTD | PMID:21570461 and PMID:28922406 | Abtb2 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of ABTB2 mRNA | CTD | PMID:21346803 | Abtb2 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ABTB2 mRNA | CTD | PMID:24780913 | Abtb2 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of ABTB2 mRNA | CTD | PMID:31881176 | Abtb2 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of ABTB2 mRNA | CTD | PMID:35163327 | Abtb2 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of ABTB2 mRNA | CTD | PMID:16483693 | Abtb2 | Rat | antirheumatic drug | decreases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of ABTB2 mRNA | CTD | PMID:24449571 | Abtb2 | Rat | aristolochic acid A | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of ABTB2 mRNA | CTD | PMID:33212167 | Abtb2 | Rat | arsane | affects methylation | ISO | ABTB2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ABTB2 gene | CTD | PMID:25304211 | Abtb2 | Rat | arsenic atom | affects methylation | ISO | ABTB2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ABTB2 gene | CTD | PMID:25304211 | Abtb2 | Rat | benzo[a]pyrene | decreases expression | ISO | Abtb2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ABTB2 mRNA | CTD | PMID:19770486 | Abtb2 | Rat | benzo[a]pyrene | increases methylation | ISO | ABTB2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ABTB2 promoter | CTD | PMID:27901495 | Abtb2 | Rat | benzo[a]pyrene | decreases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ABTB2 mRNA | CTD | PMID:26238291 | Abtb2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Abtb2 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in decreased expression of ABTB2 mRNA | CTD | PMID:21318169 | Abtb2 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of ABTB2 mRNA | CTD | PMID:31163220 | Abtb2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ABTB2 mRNA | CTD | PMID:25181051 | Abtb2 | Rat | bisphenol A | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of ABTB2 mRNA | CTD | PMID:33221593 | Abtb2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ABTB2 mRNA | CTD | PMID:32145629 | Abtb2 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of ABTB2 gene | CTD | PMID:28505145 | Abtb2 | Rat | cadmium dichloride | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of ABTB2 mRNA | CTD | PMID:38568856 | Abtb2 | Rat | caffeine | increases phosphorylation | ISO | ABTB2 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of ABTB2 protein | CTD | PMID:35688186 | Abtb2 | Rat | carbon nanotube | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | Abtb2 | Rat | carbon nanotube | decreases expression | ISO | Abtb2 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of ABTB2 mRNA | CTD | PMID:25620056 | Abtb2 | Rat | cisplatin | decreases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ABTB2 mRNA | CTD | PMID:19561079 | Abtb2 | Rat | copper(II) sulfate | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ABTB2 mRNA | CTD | PMID:19549813 | Abtb2 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of ABTB2 mRNA | CTD | PMID:26577399 | Abtb2 | Rat | cyclosporin A | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ABTB2 mRNA | CTD | PMID:20106945 | Abtb2 | Rat | cylindrospermopsin | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of ABTB2 mRNA | CTD | PMID:24921660 | Abtb2 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of ABTB2 mRNA | CTD | PMID:21266533 | Abtb2 | Rat | dicrotophos | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of ABTB2 mRNA | CTD | PMID:28302478 | Abtb2 | Rat | dinophysistoxin 1 | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | dinophysistoxin 1 results in increased expression of ABTB2 mRNA | CTD | PMID:28939011 | Abtb2 | Rat | dioxygen | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of ABTB2 mRNA | CTD | PMID:24205000 | Abtb2 | Rat | dioxygen | multiple interactions | ISO | Abtb2 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ABTB2 mRNA | CTD | PMID:30529165 | Abtb2 | Rat | diuron | decreases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Diuron results in decreased expression of ABTB2 mRNA | CTD | PMID:35967413 | Abtb2 | Rat | dorsomorphin | multiple interactions | ISO | ABTB2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABTB2 mRNA | CTD | PMID:27188386 | Abtb2 | Rat | doxorubicin | affects expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of ABTB2 mRNA | CTD | PMID:25529476 | Abtb2 | Rat | doxorubicin | decreases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ABTB2 mRNA | CTD | PMID:29803840 | Abtb2 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of ABTB2 mRNA | CTD | PMID:29391264 | Abtb2 | Rat | ethanol | affects splicing | ISO | Abtb2 (Mus musculus) | 6480464 | Ethanol affects the splicing of ABTB2 mRNA | CTD | PMID:30319688 | Abtb2 | Rat | fluoranthene | multiple interactions | ISO | Abtb2 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of ABTB2 mRNA | CTD | PMID:28329830 | Abtb2 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of ABTB2 mRNA | CTD | PMID:24136188 | Abtb2 | Rat | formaldehyde | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of ABTB2 mRNA | CTD | PMID:23649840 | Abtb2 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ABTB2 mRNA | CTD | PMID:33387578 | Abtb2 | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of ABTB2 mRNA | CTD | PMID:24136188 | Abtb2 | Rat | glyphosate | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | Glyphosate results in increased expression of ABTB2 mRNA | CTD | PMID:35897073 | Abtb2 | Rat | graphite | affects expression | EXP | | 6480464 | Graphite affects the expression of ABTB2 mRNA | CTD | PMID:29933104 | Abtb2 | Rat | hydrogen peroxide | affects expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of ABTB2 mRNA | CTD | PMID:20044591 | Abtb2 | Rat | lipopolysaccharide | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of ABTB2 mRNA | CTD | PMID:35811015 | Abtb2 | Rat | lipopolysaccharide | multiple interactions | ISO | ABTB2 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | Abtb2 | Rat | methylmercury chloride | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of ABTB2 mRNA | CTD | PMID:28001369 | Abtb2 | Rat | N-nitrosodiethylamine | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of ABTB2 mRNA | CTD | PMID:17942915 | Abtb2 | Rat | N-nitrosodiethylamine | multiple interactions | ISO | Abtb2 (Mus musculus) | 6480464 | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ABTB2 mRNA] | CTD | PMID:17942915 | Abtb2 | Rat | paracetamol | affects expression | ISO | Abtb2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ABTB2 mRNA | CTD | PMID:17562736 | Abtb2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ABTB2 mRNA | CTD | PMID:33387578 | Abtb2 | Rat | paracetamol | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ABTB2 mRNA | CTD | PMID:21420995 and PMID:29067470 | Abtb2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Abtb2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ABTB2 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of ABTB2 mRNA | CTD | PMID:36331819 | Abtb2 | Rat | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of ABTB2 mRNA | CTD | PMID:19162173 and PMID:21318169 | Abtb2 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of ABTB2 mRNA | CTD | PMID:35163327 | Abtb2 | Rat | phenobarbital | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of ABTB2 mRNA | CTD | PMID:19270015 | Abtb2 | Rat | phenobarbital | affects expression | ISO | Abtb2 (Mus musculus) | 6480464 | Phenobarbital affects the expression of ABTB2 mRNA | CTD | PMID:23091169 | Abtb2 | Rat | phenobarbital | affects expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of ABTB2 mRNA | CTD | PMID:19159669 | Abtb2 | Rat | phenylmercury acetate | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of ABTB2 mRNA | CTD | PMID:26272509 | Abtb2 | Rat | phenylmercury acetate | multiple interactions | ISO | ABTB2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABTB2 mRNA | CTD | PMID:27188386 | Abtb2 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of ABTB2 mRNA | CTD | PMID:19162173 | Abtb2 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Abtb2 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of ABTB2 mRNA | CTD | PMID:28903501 | Abtb2 | Rat | resveratrol | multiple interactions | ISO | Abtb2 (Mus musculus) | 6480464 | Resveratrol inhibits the reaction [titanium dioxide results in increased expression of ABTB2 mRNA] | CTD | PMID:31298478 | Abtb2 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | ABTB2 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | Abtb2 | Rat | SB 431542 | multiple interactions | ISO | ABTB2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABTB2 mRNA | CTD | PMID:27188386 | Abtb2 | Rat | senecionine | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | senecionine results in increased expression of ABTB2 protein | CTD | PMID:35357534 | Abtb2 | Rat | silicon dioxide | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of ABTB2 mRNA | CTD | PMID:25351596 | Abtb2 | Rat | sodium arsenite | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ABTB2 mRNA | CTD | PMID:21281968 and PMID:38568856 | Abtb2 | Rat | sodium arsenite | decreases expression | ISO | Abtb2 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of ABTB2 mRNA | CTD | PMID:37682722 | Abtb2 | Rat | succimer | multiple interactions | ISO | Abtb2 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of ABTB2 mRNA | CTD | PMID:21641980 | Abtb2 | Rat | tetrachloromethane | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of ABTB2 mRNA | CTD | PMID:17484886 and PMID:31919559 | Abtb2 | Rat | thiram | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Thiram results in increased expression of ABTB2 mRNA | CTD | PMID:38568856 | Abtb2 | Rat | titanium dioxide | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of ABTB2 mRNA | CTD | PMID:31298478 | Abtb2 | Rat | titanium dioxide | decreases methylation | ISO | Abtb2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of ABTB2 promoter | CTD | PMID:35295148 | Abtb2 | Rat | titanium dioxide | increases methylation | ISO | Abtb2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of ABTB2 gene | CTD | PMID:35295148 | Abtb2 | Rat | titanium dioxide | multiple interactions | ISO | Abtb2 (Mus musculus) | 6480464 | Resveratrol inhibits the reaction [titanium dioxide results in increased expression of ABTB2 mRNA] | CTD | PMID:31298478 | Abtb2 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of ABTB2 mRNA | CTD | PMID:33387578 | Abtb2 | Rat | triclosan | decreases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of ABTB2 mRNA | CTD | PMID:30510588 | Abtb2 | Rat | triphenyl phosphate | affects expression | ISO | ABTB2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ABTB2 mRNA | CTD | PMID:37042841 | Abtb2 | Rat | Triptolide | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | triptolide results in increased expression of ABTB2 mRNA | CTD | PMID:32835833 | Abtb2 | Rat | triptonide | increases expression | ISO | Abtb2 (Mus musculus) | 6480464 | triptonide results in increased expression of ABTB2 mRNA | CTD | PMID:33045310 | Abtb2 | Rat | undecane | decreases expression | EXP | | 6480464 | undecane results in decreased expression of ABTB2 protein | CTD | PMID:17337753 | Abtb2 | Rat | urethane | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Urethane results in increased expression of ABTB2 mRNA | CTD | PMID:28818685 | Abtb2 | Rat | valproic acid | affects expression | ISO | Abtb2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of ABTB2 mRNA | CTD | PMID:17292431 and PMID:17963808 | Abtb2 | Rat | valproic acid | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ABTB2 mRNA | CTD | PMID:24383497 more ... | Abtb2 | Rat | valproic acid | decreases methylation | ISO | ABTB2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of ABTB2 gene | CTD | PMID:29154799 | Abtb2 | Rat | vincristine | increases expression | ISO | ABTB2 (Homo sapiens) | 6480464 | Vincristine results in increased expression of ABTB2 mRNA | CTD | PMID:23649840 | Abtb2 | Rat | zinc atom | multiple interactions | ISO | ABTB2 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of ABTB2 mRNA | CTD | PMID:18593933 | Abtb2 | Rat | zinc(0) | multiple interactions | ISO | ABTB2 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of ABTB2 mRNA | CTD | PMID:18593933 | |