Vapa (VAMP associated protein A) - Rat Genome Database

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Gene: Vapa (VAMP associated protein A) Rattus norvegicus
Analyze
Symbol: Vapa
Name: VAMP associated protein A
RGD ID: 61803
Description: Enables identical protein binding activity. Involved in neuron projection development. Located in endoplasmic reticulum membrane and nuclear membrane. Orthologous to human VAPA (VAMP associated protein A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 33 kDa Vamp-associated protein; VAMP (vesicle-associated membrane protein)-associated protein A; VAMP-A; VAMP-associated protein A; VAP-33; VAP-A; vesicle-associated membrane protein associated protein A (33 kDa); vesicle-associated membrane protein, associated protein a; vesicle-associated membrane protein, associated protein A (33 kDa); vesicle-associated membrane protein-associated protein A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89112,624,791 - 112,654,731 (-)NCBIGRCr8
mRatBN7.29105,177,904 - 105,208,400 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9105,177,907 - 105,207,847 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9113,588,500 - 113,618,316 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09118,698,807 - 118,728,640 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09117,054,450 - 117,084,266 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09113,300,831 - 113,331,872 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9113,300,832 - 113,331,319 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09112,833,701 - 112,864,112 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49104,339,039 - 104,368,908 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19104,548,519 - 104,578,388 (-)NCBI
Celera9102,564,697 - 102,594,412 (-)NCBICelera
Cytogenetic Map9q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
VapaRatchromosome 18p deletion syndrome  ISOVAPA (Homo sapiens)8554872ClinVar Annotator: match by term: Del(18p) syndromeClinVarPMID:31690835
VapaRatdystonia  ISOVAPA (Homo sapiens)8554872ClinVar Annotator: match by term: Dystonic disorderClinVarPMID:25817843 and PMID:28492532
VapaRatintellectual disability  ISOVAPA (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
VapaRat1,2-dimethylhydrazine decreases expressionISOVapa (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of VAPA mRNACTDPMID:22206623
VapaRat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOVAPA (Homo sapiens)64804642 more ...CTDPMID:31675489
VapaRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOVapa (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of VAPA mRNACTDPMID:21570461
VapaRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of VAPA mRNACTDPMID:34747641
VapaRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOVAPA (Homo sapiens)6480464[Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in decreased expression of VAPA mRNACTDPMID:29704546
VapaRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of VAPA mRNACTDPMID:26232522
VapaRat2,4,6-tribromophenol decreases expressionISOVAPA (Homo sapiens)64804642 more ...CTDPMID:31675489
VapaRat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of VAPA mRNACTDPMID:21346803
VapaRat2,6-dimethoxyphenol multiple interactionsISOVAPA (Homo sapiens)6480464[pyrogallol 1 and 3-dimethyl ether co-treated with Furaldehyde] results in decreased expression of and affects the localization of VAPA proteinCTDPMID:38598786
VapaRat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of VAPA mRNACTDPMID:21346803
VapaRat3,3',5,5'-tetrabromobisphenol A decreases expressionISOVAPA (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of VAPA proteinCTDPMID:31675489
VapaRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOVAPA (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of VAPA mRNACTDPMID:28628672
VapaRat4,4'-sulfonyldiphenol increases expressionISOVapa (Mus musculus)6480464bisphenol S results in increased expression of VAPA mRNACTDPMID:39298647
VapaRat4,4'-sulfonyldiphenol increases expressionISOVAPA (Homo sapiens)6480464bisphenol S results in increased expression of VAPA proteinCTDPMID:34186270
VapaRat4,4'-sulfonyldiphenol multiple interactionsISOVAPA (Homo sapiens)6480464[bisphenol S co-treated with Fulvestrant] results in decreased methylation of VAPA geneCTDPMID:31601247
VapaRat4,4'-sulfonyldiphenol affects expressionISOVAPA (Homo sapiens)6480464bisphenol S affects the expression of VAPA proteinCTDPMID:31945527
VapaRatacrolein multiple interactionsISOVAPA (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of VAPA mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of VAPA mRNACTDPMID:32699268
VapaRataflatoxin B1 increases methylationISOVAPA (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of VAPA geneCTDPMID:27153756
VapaRatalpha-pinene multiple interactionsISOVAPA (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of VAPA mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of VAPA mRNACTDPMID:32699268
VapaRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of VAPA mRNACTDPMID:16483693

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Biological Process
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
VapaRatceramide transport involved_inISOVAPA (Homo sapiens)1624291 PMID:12023275RGDPMID:12023275
VapaRatcholesterol transport involved_inISOVAPA (Homo sapiens)1624291 PMID:33124732RGDPMID:33124732
VapaRatCOPII-coated vesicle budding involved_inISOVAPA (Homo sapiens)1624291 PMID:18713837RGDPMID:18713837
VapaRatendoplasmic reticulum organization NOT|involved_inISOVAPA (Homo sapiens)1624291 PMID:18713837RGDPMID:18713837
VapaRatendoplasmic reticulum to Golgi vesicle-mediated transport involved_inISOVAPA (Homo sapiens)1624291 PMID:18713837RGDPMID:18713837
VapaRatendoplasmic reticulum-plasma membrane tethering involved_inISOVAPA (Homo sapiens)1624291 PMID:33124732RGDPMID:33124732
VapaRatnegative regulation by host of viral genome replication involved_inISOVAPA (Homo sapiens)1624291 PMID:19515777RGDPMID:19515777
VapaRatneuron projection development involved_inIMP 8554038PMID:19289470UniProt 
VapaRatneuron projection development involved_inIBAPANTHER:PTN002585160 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
VapaRatneuron projection development involved_inISOVAPA (Homo sapiens)1624291 PMID:19289470RGDPMID:19289470
VapaRatphospholipid transport involved_inISOVAPA (Homo sapiens)1624291 PMID:24209621RGDPMID:24209621
VapaRatpositive regulation by host of viral genome replication involved_inISOVAPA (Homo sapiens)1624291 PMID:19515777RGDPMID:19515777
VapaRatpositive regulation of canonical NF-kappaB signal transduction involved_inISOVAPA (Homo sapiens)9068941 PMID:12761501UniProtPMID:12761501
VapaRatprotein folding in endoplasmic reticulum NOT|involved_inISOVAPA (Homo sapiens)1624291 PMID:18713837RGDPMID:18713837
VapaRatprotein localization to endoplasmic reticulum involved_inISSUniProtKB:Q9P0L01600115GO_REF:0000024UniProtGO_REF:0000024
VapaRatprotein localization to endoplasmic reticulum involved_inISOVAPA (Homo sapiens)1624291 PMID:19289470RGDPMID:19289470
VapaRatsphingomyelin biosynthetic process involved_inISOVAPA (Homo sapiens)1624291 PMID:12023275RGDPMID:12023275
VapaRatsterol transport involved_inISOVAPA (Homo sapiens)1624291 PMID:24209621RGDPMID:24209621
VapaRatviral release from host cell involved_inISOVAPA (Homo sapiens)1624291 PMID:19515777RGDPMID:19515777
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Cellular Component
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
VapaRatanchoring junction located_inIEAUniProtKB-KW:KW-09651600115GO_REF:0000043UniProtGO_REF:0000043
VapaRatbicellular tight junction located_inIEAUniProtKB-SubCell:SL-02651600115GO_REF:0000044UniProtGO_REF:0000044
VapaRatbicellular tight junction located_inIEAUniProtKB-KW:KW-07961600115GO_REF:0000043UniProtGO_REF:0000043
VapaRatbicellular tight junction located_inISOVAPA (Homo sapiens)1624291 PMID:10523508RGDPMID:10523508
VapaRatendoplasmic reticulum located_inISOVAPA (Homo sapiens)1624291 PMID:18713837 and PMID:19289470RGDPMID:18713837 and PMID:19289470
VapaRatendoplasmic reticulum located_inISOVapa (Mus musculus)1624291 PMID:10655491RGDPMID:10655491
VapaRatendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
VapaRatendoplasmic reticulum located_inIEAUniProtKB:Q9WV55 and ensembl:ENSMUSP000000248971600115GO_REF:0000107EnsemblGO_REF:0000107
VapaRatendoplasmic reticulum located_inISSUniProtKB:Q9P0L01600115GO_REF:0000024UniProtGO_REF:0000024
VapaRatendoplasmic reticulum located_inISOVAPA (Homo sapiens) and UniProtKB:Q9P0L0-21624291 RGDGO_REF:0000052
VapaRatendoplasmic reticulum exit site NOT|located_inISOVAPA (Homo sapiens)1624291 PMID:18713837RGDPMID:18713837
VapaRatendoplasmic reticulum membrane located_inIDA 11059584PMID:24262037UniProt 
VapaRatendoplasmic reticulum membrane located_inISOVAPA (Homo sapiens)1624291 PMID:12023275 more ...RGDPMID:12023275 more ...
VapaRatendoplasmic reticulum membrane is_active_inIBAPANTHER:PTN000087323 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
VapaRatendoplasmic reticulum membrane located_inIEAInterPro:IPR0167631600115GO_REF:0000002InterProGO_REF:0000002
VapaRatendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00971600115GO_REF:0000044UniProtGO_REF:0000044
VapaRatGolgi membrane located_inISOVAPA (Homo sapiens)1624291 PMID:24209621RGDPMID:24209621
VapaRatmembrane located_inIDA 1580664PMID:14561759BHF-UCL 
VapaRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
VapaRatmicrotubule cytoskeleton located_inIEAUniProtKB:Q9WV55 and ensembl:ENSMUSP000000248971600115GO_REF:0000107EnsemblGO_REF:0000107
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Structural basis of FFAT motif-mediated ER targeting. Kaiser SE, etal., Structure. 2005 Jul;13(7):1035-45.
4. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins. Nishimura Y, etal., Biochem Biophys Res Commun 1999 Jan 8;254(1):21-6.
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein. Saita S, etal., J Biol Chem. 2009 May 15;284(20):13766-77. doi: 10.1074/jbc.M807938200. Epub 2009 Mar 16.
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
12. Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion. Yamamoto Y, etal., Biochem J. 2014 Feb 15;458(1):69-79. doi: 10.1042/BJ20131186.
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PMID:10523508   PMID:10655491   PMID:12477932   PMID:12761501   PMID:15489334   PMID:16025302   PMID:16227268   PMID:16791210   PMID:16895911   PMID:18504258   PMID:18713837   PMID:19515777  
PMID:20178991   PMID:21700703   PMID:24105263   PMID:25468996   PMID:29476059   PMID:29941597   PMID:30741634   PMID:31594761  



Vapa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89112,624,791 - 112,654,731 (-)NCBIGRCr8
mRatBN7.29105,177,904 - 105,208,400 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9105,177,907 - 105,207,847 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9113,588,500 - 113,618,316 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09118,698,807 - 118,728,640 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09117,054,450 - 117,084,266 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09113,300,831 - 113,331,872 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9113,300,832 - 113,331,319 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09112,833,701 - 112,864,112 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49104,339,039 - 104,368,908 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19104,548,519 - 104,578,388 (-)NCBI
Celera9102,564,697 - 102,594,412 (-)NCBICelera
Cytogenetic Map9q37NCBI
VAPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38189,914,016 - 9,960,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl189,914,016 - 9,960,021 (+)EnsemblGRCh38hg38GRCh38
GRCh37189,914,013 - 9,960,018 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36189,903,955 - 9,950,018 (+)NCBINCBI36Build 36hg18NCBI36
Build 34189,903,983 - 9,949,571NCBI
Celera189,797,515 - 9,843,493 (+)NCBICelera
Cytogenetic Map18p11.22NCBI
HuRef189,893,891 - 9,921,843 (+)NCBIHuRef
CHM1_1189,913,226 - 9,959,178 (+)NCBICHM1_1
T2T-CHM13v2.01810,077,467 - 10,123,397 (+)NCBIT2T-CHM13v2.0
Vapa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391765,887,048 - 65,925,441 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1765,885,322 - 65,920,550 (-)EnsemblGRCm39 Ensembl
GRCm381765,580,053 - 65,616,462 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1765,578,327 - 65,613,555 (-)EnsemblGRCm38mm10GRCm38
MGSCv371765,929,393 - 65,962,895 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361765,479,598 - 65,513,084 (-)NCBIMGSCv36mm8
Celera1769,883,322 - 69,916,704 (-)NCBICelera
Cytogenetic Map17E1.1NCBI
cM Map1734.9NCBI
Vapa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554022,270,850 - 2,298,227 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554022,274,248 - 2,309,461 (-)NCBIChiLan1.0ChiLan1.0
VAPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21728,496,390 - 28,537,484 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11814,188,987 - 14,230,079 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0184,329,479 - 4,373,047 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1186,613,042 - 6,642,425 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl186,612,105 - 6,637,829 (-)Ensemblpanpan1.1panPan2
VAPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1775,844,927 - 75,891,811 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl775,845,000 - 75,889,076 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha775,242,387 - 75,289,206 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0775,905,356 - 75,948,878 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl775,905,322 - 75,949,488 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1775,603,405 - 75,650,255 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0775,621,438 - 75,668,178 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0775,930,605 - 75,977,554 (+)NCBIUU_Cfam_GSD_1.0
Vapa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049442,321,989 - 2,357,518 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366261,548,139 - 1,568,656 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366261,550,305 - 1,585,783 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VAPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl698,210,053 - 98,254,226 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1698,212,335 - 98,254,272 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
VAPA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11868,784,786 - 68,825,333 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1868,784,799 - 68,827,581 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605043,739,425 - 43,782,261 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vapa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477018,411,789 - 18,447,009 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477018,411,921 - 18,447,004 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Vapa
57 total Variants

Predicted Target Of
Summary Value
Count of predictions:526
Count of miRNA genes:251
Interacting mature miRNAs:307
Transcripts:ENSRNOT00000020681
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat

RH76596  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29105,177,948 - 105,178,119 (+)MAPPERmRatBN7.2
Rnor_6.09113,300,876 - 113,301,046NCBIRnor6.0
Rnor_5.09112,833,746 - 112,833,916UniSTSRnor5.0
RGSC_v3.49104,339,084 - 104,339,254UniSTSRGSC3.4
Celera9102,564,742 - 102,564,912UniSTS
Cytogenetic Map9q37UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000020681   ⟹   ENSRNOP00000020681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9105,177,907 - 105,207,847 (-)Ensembl
Rnor_6.0 Ensembl9113,300,832 - 113,331,319 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086340   ⟹   ENSRNOP00000074577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9105,177,907 - 105,191,458 (-)Ensembl
Rnor_6.0 Ensembl9113,301,256 - 113,328,428 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113264   ⟹   ENSRNOP00000083505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9105,177,907 - 105,207,847 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117261   ⟹   ENSRNOP00000089269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9105,177,907 - 105,204,749 (-)Ensembl
RefSeq Acc Id: NM_031631   ⟹   NP_113819
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89112,624,791 - 112,654,731 (-)NCBI
mRatBN7.29105,177,904 - 105,207,847 (-)NCBI
Rnor_6.09113,300,831 - 113,331,319 (-)NCBI
Rnor_5.09112,833,701 - 112,864,112 (-)NCBI
RGSC_v3.49104,339,039 - 104,368,908 (-)RGD
Celera9102,564,697 - 102,594,412 (-)RGD
Sequence:
RefSeq Acc Id: XM_008767384   ⟹   XP_008765606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89112,624,791 - 112,654,703 (-)NCBI
mRatBN7.29105,177,904 - 105,208,400 (-)NCBI
Rnor_6.09113,300,831 - 113,331,872 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039084144   ⟹   XP_038940072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89112,624,791 - 112,654,703 (-)NCBI
mRatBN7.29105,177,904 - 105,207,808 (-)NCBI
RefSeq Acc Id: XM_039084145   ⟹   XP_038940073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89112,624,791 - 112,654,222 (-)NCBI
mRatBN7.29105,177,904 - 105,204,764 (-)NCBI
RefSeq Acc Id: XM_063267660   ⟹   XP_063123730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89112,624,791 - 112,651,838 (-)NCBI
RefSeq Acc Id: NP_113819   ⟸   NM_031631
- UniProtKB: Q6P723 (UniProtKB/Swiss-Prot),   Q9Z270 (UniProtKB/Swiss-Prot),   A6JRB7 (UniProtKB/TrEMBL),   A0A0G2K8E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765606   ⟸   XM_008767384
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZVH7 (UniProtKB/TrEMBL),   A6JRB8 (UniProtKB/TrEMBL),   A0A0G2K8E6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020681   ⟸   ENSRNOT00000020681
Ensembl Acc Id: ENSRNOP00000074577   ⟸   ENSRNOT00000086340
RefSeq Acc Id: XP_038940072   ⟸   XM_039084144
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K8E6 (UniProtKB/TrEMBL)
MSP

Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z270-F1-model_v2 AlphaFold Q9Z270 1-249 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696902
Promoter ID:EPDNEW_R7426
Type:initiation region
Name:Vapa_1
Description:VAMP associated protein A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.09113,331,278 - 113,331,338EPDNEW


1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-26488 BioCyc
Ensembl Genes ENSRNOG00000014765 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020681 ENTREZGENE
  ENSRNOT00000020681.7 UniProtKB/Swiss-Prot
  ENSRNOT00000086340 ENTREZGENE
  ENSRNOT00000113264 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5598274 IMAGE-MGC_LOAD
InterPro Ig-like_fold UniProtKB/Swiss-Prot
  MSP_dom UniProtKB/Swiss-Prot
  PapD-like_sf UniProtKB/Swiss-Prot
  VAP UniProtKB/Swiss-Prot
KEGG Report rno:58857 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72396 IMAGE-MGC_LOAD
NCBI Gene 58857 ENTREZGENE
PANTHER PTHR10809 UniProtKB/Swiss-Prot
  VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A UniProtKB/Swiss-Prot
Pfam Motile_Sperm UniProtKB/Swiss-Prot
PhenoGen Vapa PhenoGen
PIRSF VAMP-associated UniProtKB/Swiss-Prot
PROSITE MSP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014765 RatGTEx
Superfamily-SCOP SSF49354 UniProtKB/Swiss-Prot
TIGR TC217149
UniProt A0A0G2K8E6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZVH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GHY4 ENTREZGENE, UniProtKB/TrEMBL
  A6JRB7 ENTREZGENE, UniProtKB/TrEMBL
  A6JRB8 ENTREZGENE, UniProtKB/TrEMBL
  A6JRB9_RAT UniProtKB/TrEMBL
  Q6P723 ENTREZGENE
  Q9Z270 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q6P723 UniProtKB/Swiss-Prot
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-11 Vapa  VAMP associated protein A  Vapa  VAMP (vesicle-associated membrane protein)-associated protein A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Vapa  VAMP (vesicle-associated membrane protein)-associated protein A  Vapa  vesicle-associated membrane protein, associated protein a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Vapa  vesicle-associated membrane protein, associated protein a      Name updated 70584 APPROVED

Note Type Note Reference
gene_domains contains coiled-coil, t-SNARE homology domain near the carboxyl-terminal 61779
gene_expression ubiquitously expressed 61779