Mup4l3 (major urinary protein 4 like 3) - Rat Genome Database

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Gene: Mup4l3 (major urinary protein 4 like 3) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Mup4l3 (Ensembl: Mup5)
Name: major urinary protein 4 like 3 (Ensembl:major urinary protein 5)
RGD ID: 1593272
Description: Predicted to enable pheromone binding activity and small molecule binding activity. Predicted to be located in extracellular region.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha2u globulin; LOC103690101; LOC298111; major urinary protein-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8580,314,061 - 80,318,373 (-)NCBIGRCr8
mRatBN7.2575,311,713 - 75,316,792 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl575,142,157 - 75,564,845 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx577,419,904 - 77,626,864 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0579,241,566 - 79,448,528 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0579,213,717 - 79,420,686 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0552,765,500 - 52,767,592 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl577,564,024 - 77,903,062 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0557,209,509 - 57,211,796 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4578,818,793 - 78,822,494 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera566,162,605 - 66,164,869 (-)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mup4l3Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Mup4l3Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mup4l3Ratpheromone binding enablesIEAUniProtKB-KW:KW-05901600115GO_REF:0000043UniProtGO_REF:0000043
Mup4l3Ratsmall molecule binding enablesIEAInterPro:IPR0023451600115GO_REF:0000002InterProGO_REF:0000002


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
PMID:2473438  



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Variants in Mup4l3
176 total Variants

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:59
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000074349
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 39 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat

1 to 10 of 39 rows



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 5 15 30 32 21 1 21 6 37 11 8 2 13 11



Ensembl Acc Id: ENSRNOT00000074349   ⟹   ENSRNOP00000067018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl577,564,024 - 77,903,062 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076791   ⟹   ENSRNOP00000067914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl577,722,817 - 77,725,867 (-)Ensembl
RefSeq Acc Id: NM_001024248   ⟹   NP_001019419
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8580,314,061 - 80,318,372 (-)NCBI
mRatBN7.2575,312,314 - 75,316,625 (-)NCBI
Rnor_6.0552,765,500 - 52,767,592 (-)NCBI
Rnor_5.0557,209,509 - 57,211,796 (-)NCBI
RGSC_v3.4578,818,793 - 78,822,494 (-)RGD
Celera566,162,605 - 66,164,869 (-)RGD
Sequence:
RefSeq Acc Id: XM_063287356   ⟹   XP_063143426
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8580,315,985 - 80,318,373 (-)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001019419 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143426 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA32598 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012293.6
  ENSRNOP00000067018
  ENSRNOP00000067018.3
  ENSRNOP00000067914.2
  ENSRNOP00000068285.2
  ENSRNOP00000084655.1
  ENSRNOP00000088900.1
1 to 10 of 10 rows
RefSeq Acc Id: NP_001019419   ⟸   NM_001024248
- Peptide Label: precursor
- UniProtKB: Q8K1Q7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067018   ⟸   ENSRNOT00000074349
Ensembl Acc Id: ENSRNOP00000067914   ⟸   ENSRNOT00000076791
RefSeq Acc Id: XP_063143426   ⟸   XM_063287356
- Peptide Label: isoform X1
- UniProtKB: Q8K1Q7 (UniProtKB/TrEMBL)
Lipocalin/cytosolic fatty-acid binding

Name Modeler Protein Id AA Range Protein Structure
AF-M0RBS2-F1-model_v2 AlphaFold M0RBS2 1-181 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 37 of 37 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-41114 BioCyc
Ensembl Genes ENSRNOG00000049727 Ensembl
  ENSRNOG00000067602 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000080617 ENTREZGENE
Ensembl Transcript ENSRNOT00000012293.5 UniProtKB/TrEMBL
  ENSRNOT00000074349 ENTREZGENE
  ENSRNOT00000074349.3 UniProtKB/TrEMBL
  ENSRNOT00000076466.2 UniProtKB/TrEMBL
  ENSRNOT00000076791.3 UniProtKB/TrEMBL
  ENSRNOT00000094674.1 UniProtKB/TrEMBL
  ENSRNOT00000106951.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.128.20 UniProtKB/TrEMBL
InterPro Calycin UniProtKB/TrEMBL
  Lipocalin UniProtKB/TrEMBL
  Lipocalin_CS UniProtKB/TrEMBL
  Lipocln_cytosolic_FA-bd_dom UniProtKB/TrEMBL
  Maj_urinary UniProtKB/TrEMBL
KEGG Report rno:298111 UniProtKB/TrEMBL
NCBI Gene 298111 ENTREZGENE
PANTHER MAJOR URINARY PROTEIN 1-RELATED UniProtKB/TrEMBL
  PTHR11430 UniProtKB/TrEMBL
Pfam Lipocalin UniProtKB/TrEMBL
PhenoGen Mup4l3 PhenoGen
PRINTS LIPOCALIN UniProtKB/TrEMBL
  MAJORURINARY UniProtKB/TrEMBL
PROSITE LIPOCALIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049727 RatGTEx
  ENSRNOG00000067602 RatGTEx
  ENSRNOG00000080617 RatGTEx
Superfamily-SCOP Calycin UniProtKB/TrEMBL
UniProt A0A096MIX6_RAT UniProtKB/TrEMBL
  A0A096MJW3_RAT UniProtKB/TrEMBL
  A0A8I5ZYK0_RAT UniProtKB/TrEMBL
  A0A8I6A7F8_RAT UniProtKB/TrEMBL
  F7ET54_RAT UniProtKB/TrEMBL
  M0RBS2_RAT UniProtKB/TrEMBL
  Q8K1Q7 ENTREZGENE, UniProtKB/TrEMBL
1 to 37 of 37 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Mup4l3  major urinary protein 4 like 3  LOC298111  alpha2u globulin  Symbol and Name Changed 1299863 APPROVED
2021-03-09 LOC298111  alpha2u globulin  LOC103690101  major urinary protein-like  Data merged from RGD:9087734 737654 PROVISIONAL
2014-08-25 LOC103690101  major urinary protein-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC298111  alpha2u globulin      Symbol and Name status set to provisional 70820 PROVISIONAL