Ano2 (anoctamin 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Ano2 (anoctamin 2) Rattus norvegicus
Analyze
Symbol: Ano2
Name: anoctamin 2
RGD ID: 1591606
Description: Enables intracellularly calcium-gated chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to act upstream of or within chloride transport and establishment of localization in cell. Predicted to be located in neuron projection; non-motile cilium; and nucleoplasm. Predicted to be active in glutamatergic synapse and presynaptic membrane. Orthologous to human ANO2 (anoctamin 2); INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: anoctamin 2, calcium activated chloride channel; anoctamin 2-like; anoctamin-2; anoctamin-2-like; LOC100361584; LOC100912468; LOC683001; similar to Transmembrane protein 16B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84160,200,471 - 160,541,830 (+)NCBIGRCr8
mRatBN7.24158,514,200 - 158,855,639 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4158,496,014 - 158,855,651 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.04158,222,650 - 158,577,595 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4158,224,000 - 158,576,978 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04225,312,041 - 225,579,493 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44162,315,059 - 162,376,029 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4147,226,836 - 147,581,598 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels. Vocke K, etal., J Gen Physiol. 2013 Oct;142(4):381-404. doi: 10.1085/jgp.201311015.
Additional References at PubMed
PMID:15632090   PMID:19474308   PMID:19475416   PMID:19561302   PMID:20056604   PMID:21516098   PMID:21984732   PMID:22075693   PMID:22314846   PMID:23532839   PMID:23557741   PMID:23576756  
PMID:29187602  


Genomics

Comparative Map Data
Ano2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84160,200,471 - 160,541,830 (+)NCBIGRCr8
mRatBN7.24158,514,200 - 158,855,639 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4158,496,014 - 158,855,651 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.04158,222,650 - 158,577,595 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4158,224,000 - 158,576,978 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04225,312,041 - 225,579,493 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44162,315,059 - 162,376,029 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4147,226,836 - 147,581,598 (+)NCBICelera
Cytogenetic Map4q42NCBI
ANO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38125,562,655 - 5,946,232 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl125,531,869 - 5,946,232 (-)EnsemblGRCh38hg38GRCh38
GRCh37125,671,821 - 6,055,398 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36125,542,081 - 5,925,659 (-)NCBINCBI36Build 36hg18NCBI36
Build 34125,542,080 - 5,925,659NCBI
Celera127,292,577 - 7,675,047 (-)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef125,525,403 - 5,907,364 (-)NCBIHuRef
CHM1_1125,671,608 - 6,054,794 (-)NCBICHM1_1
T2T-CHM13v2.0125,569,523 - 5,953,779 (-)NCBIT2T-CHM13v2.0
Ano2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396125,667,382 - 126,017,115 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6125,667,382 - 126,017,089 (+)EnsemblGRCm39 Ensembl
GRCm386125,690,419 - 126,040,133 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6125,690,419 - 126,040,126 (+)EnsemblGRCm38mm10GRCm38
MGSCv376125,640,437 - 125,990,151 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366125,676,322 - 126,005,752 (+)NCBIMGSCv36mm8
MGSCv366126,602,651 - 126,934,718 (+)NCBIMGSCv36mm8
Celera6127,350,653 - 127,704,257 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map659.58NCBI
Ano2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554133,333,289 - 3,668,587 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554133,333,275 - 3,650,255 (-)NCBIChiLan1.0ChiLan1.0
ANO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21011,117,549 - 11,501,548 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11211,114,307 - 11,498,306 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,690,023 - 6,071,283 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1125,608,895 - 5,987,004 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl125,609,541 - 5,987,900 (-)Ensemblpanpan1.1panPan2
ANO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,976,761 - 39,320,764 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,833,837 - 39,320,142 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,295,718 - 7,637,739 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02739,333,634 - 39,677,324 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2739,332,399 - 39,697,998 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12739,204,162 - 39,546,469 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02739,246,081 - 39,587,939 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0276,773,567 - 7,115,529 (-)NCBIUU_Cfam_GSD_1.0
Ano2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945103,078,168 - 103,430,124 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367091,745,804 - 2,096,989 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367091,771,763 - 2,097,668 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1115,610,509 - 5,970,580 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl115,611,162 - 5,969,478 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660632,246,131 - 2,623,038 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ano2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248602,531,904 - 2,854,862 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248602,531,196 - 2,835,248 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ano2
2508 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:40
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000032112
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
1581574Eae20Experimental allergic encephalomyelitis QTL 207.8nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4153031106158841762Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4157680158158841762Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157710145182687754Rat

Markers in Region
D4Got132  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24158,841,508 - 158,841,762 (+)MAPPERmRatBN7.2
Rnor_6.04158,564,220 - 158,564,471NCBIRnor6.0
Rnor_5.04225,566,118 - 225,566,369UniSTSRnor5.0
RGSC_v3.44162,361,892 - 162,362,144RGDRGSC3.4
RGSC_v3.44162,361,893 - 162,362,144UniSTSRGSC3.4
RGSC_v3.14162,606,829 - 162,607,080RGD
Celera4147,567,471 - 147,567,722UniSTS
RH 3.4 Map41002.1RGD
RH 3.4 Map41002.1UniSTS
BE120014  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24158,599,853 - 158,600,006 (+)MAPPERmRatBN7.2
Rnor_6.04158,324,425 - 158,324,577NCBIRnor6.0
Rnor_5.04225,326,862 - 225,327,014UniSTSRnor5.0
RGSC_v3.44161,966,447 - 161,966,599UniSTSRGSC3.4
Celera4147,325,789 - 147,325,941UniSTS
RH 3.4 Map41010.7UniSTS
AU046876  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24158,694,785 - 158,694,918 (+)MAPPERmRatBN7.2
Rnor_6.04158,418,261 - 158,418,393NCBIRnor6.0
Rnor_5.04225,420,347 - 225,420,479UniSTSRnor5.0
RGSC_v3.44162,063,311 - 162,063,443UniSTSRGSC3.4
Celera4147,420,902 - 147,421,036UniSTS
RH139336  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24158,741,748 - 158,741,980 (+)MAPPERmRatBN7.2
Rnor_6.04158,466,018 - 158,466,249NCBIRnor6.0
Rnor_5.04225,468,104 - 225,468,335UniSTSRnor5.0
RGSC_v3.44162,110,276 - 162,110,507UniSTSRGSC3.4
Celera4147,467,848 - 147,468,079UniSTS
RH 3.4 Map4348.11UniSTS
AU049195  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24158,822,360 - 158,822,615 (+)MAPPERmRatBN7.2
Rnor_6.04158,545,629 - 158,545,883NCBIRnor6.0
Rnor_5.04225,547,527 - 225,547,781UniSTSRnor5.0
RGSC_v3.44162,342,880 - 162,343,134UniSTSRGSC3.4
Celera4147,548,288 - 147,548,542UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 29 3 2 1 2 4 5 33 9 7 9 4
Below cutoff 14 32 19 10 19 4 6 41 26 32 2 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000032112   ⟹   ENSRNOP00000030034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4158,514,857 - 158,855,651 (+)Ensembl
Rnor_6.0 Ensembl4158,243,086 - 158,576,978 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000078495   ⟹   ENSRNOP00000068994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4158,514,857 - 158,855,651 (+)Ensembl
Rnor_6.0 Ensembl4158,224,000 - 158,576,978 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000084240   ⟹   ENSRNOP00000070208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4158,496,014 - 158,855,651 (+)Ensembl
Rnor_6.0 Ensembl4158,224,000 - 158,576,978 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119671   ⟹   ENSRNOP00000090974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4158,514,861 - 158,855,651 (+)Ensembl
RefSeq Acc Id: XM_017593038   ⟹   XP_017448527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84160,200,471 - 160,541,830 (+)NCBI
mRatBN7.24158,514,201 - 158,855,639 (+)NCBI
Rnor_6.04158,222,650 - 158,577,595 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039108820   ⟹   XP_038964748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84160,239,503 - 160,541,830 (+)NCBI
mRatBN7.24158,553,127 - 158,855,639 (+)NCBI
RefSeq Acc Id: XM_063286858   ⟹   XP_063142928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84160,201,105 - 160,541,830 (+)NCBI
RefSeq Acc Id: XM_063286859   ⟹   XP_063142929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84160,250,627 - 160,541,830 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_017448527   ⟸   XM_017593038
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JXB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068994   ⟸   ENSRNOT00000078495
RefSeq Acc Id: ENSRNOP00000030034   ⟸   ENSRNOT00000032112
RefSeq Acc Id: ENSRNOP00000070208   ⟸   ENSRNOT00000084240
RefSeq Acc Id: XP_038964748   ⟸   XM_039108820
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GJA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000090974   ⟸   ENSRNOT00000119671
RefSeq Acc Id: XP_063142928   ⟸   XM_063286858
- Peptide Label: isoform X1
- UniProtKB: F1M3G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142929   ⟸   XM_063286859
- Peptide Label: isoform X3
Protein Domains
Anoctamin dimerisation   Anoctamin transmembrane

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JXB5-F1-model_v2 AlphaFold A0A0G2JXB5 1-998 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591606 AgrOrtholog
BioCyc Gene G2FUF-42983 BioCyc
Ensembl Genes ENSRNOG00000023561 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032112.6 UniProtKB/TrEMBL
  ENSRNOT00000078495.2 UniProtKB/TrEMBL
  ENSRNOT00000084240.2 UniProtKB/TrEMBL
  ENSRNOT00000119671.1 UniProtKB/TrEMBL
InterPro Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
  Anoctamin_TM UniProtKB/TrEMBL
KEGG Report rno:100361584 UniProtKB/TrEMBL
NCBI Gene Ano2 ENTREZGENE
PANTHER PTHR12308 UniProtKB/TrEMBL
  PTHR12308:SF20 UniProtKB/TrEMBL
Pfam Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
PhenoGen Ano2 PhenoGen
RatGTEx ENSRNOG00000023561 RatGTEx
UniProt A0A0G2JU76_RAT UniProtKB/TrEMBL
  A0A0G2JXB5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJA0 ENTREZGENE, UniProtKB/TrEMBL
  F1M3G8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-15 Ano2  anoctamin 2  Ano2  anoctamin 2, calcium activated chloride channel  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-24 Ano2  anoctamin 2, calcium activated chloride channel  LOC100361584  anoctamin 2-like  Data merged from RGD:2319885 737654 APPROVED
2015-11-24 Ano2  anoctamin 2, calcium activated chloride channel  Ano2  anoctamin 2, calcium activated chloride channel  Type changed (type changed from [null] to [protein-coding]) 629549 APPROVED
2015-07-29 LOC100361584  anoctamin 2-like  LOC100912468  anoctamin-2-like  Data merged from RGD:6486491 737654 PROVISIONAL
2014-04-16 Ano2  anoctamin 2, calcium activated chloride channel  Ano2  anoctamin 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100912468  anoctamin-2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2011-05-13 Ano2  anoctamin 2  LOC683001  similar to Transmembrane protein 16B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100361584  anoctamin 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC683001  similar to Transmembrane protein 16B      Symbol and Name status set to provisional 70820 PROVISIONAL