S1pr3 (sphingosine-1-phosphate receptor 3) - Rat Genome Database

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Gene: S1pr3 (sphingosine-1-phosphate receptor 3) Rattus norvegicus
Analyze
Symbol: S1pr3
Name: sphingosine-1-phosphate receptor 3
RGD ID: 1583843
Description: Predicted to enable G protein-coupled receptor activity and integrin binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of establishment of endothelial barrier; and regulation of metabolic process. Predicted to act upstream of or within several processes, including Notch signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and regulation of interleukin-1 beta production. Predicted to be active in cytoplasm; plasma membrane; and presynapse. Orthologous to human S1PR3 (sphingosine-1-phosphate receptor 3); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; INTERACTS WITH acetamide; aldehydo-D-glucose; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cardiac sphingosine-1-phosphate specific receptor; Edg3; Edg3l; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; LOC306792; lpb3; similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3); sphingosine 1-phosphate receptor 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81713,932,773 - 13,946,213 (-)NCBIGRCr8
mRatBN7.21713,781,050 - 13,794,408 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1713,781,050 - 13,794,505 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1713,704,546 - 13,717,841 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01715,315,258 - 15,328,555 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01713,631,365 - 13,644,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01713,799,383 - 13,812,877 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1713,799,383 - 13,812,704 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01715,871,251 - 15,884,751 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,657,822 - 19,661,106 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1713,529,246 - 13,542,351 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
apigenin  (EXP)
aristolochic acid A  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (EXP)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
Enterolactone  (ISO)
entinostat  (ISO)
enzalutamide  (ISO)
ethanol  (ISO)
fingolimod hydrochloride  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
glucose  (EXP)
glycitein  (ISO)
glycitin  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (EXP,ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nitrofen  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
propionic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
Soman  (EXP)
sphingosine 1-phosphate  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
torcetrapib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vanadyl sulfate  (ISO)
WIN 55212-2  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
plasma membrane  (IBA,ISO)
presynapse  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10220556   PMID:10915638   PMID:11443127   PMID:18305483   PMID:18535287   PMID:21887342   PMID:22828274   PMID:23117660   PMID:24851274   PMID:25869501   PMID:28634078   PMID:29266713  
PMID:29536648  


Genomics

Comparative Map Data
S1pr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81713,932,773 - 13,946,213 (-)NCBIGRCr8
mRatBN7.21713,781,050 - 13,794,408 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1713,781,050 - 13,794,505 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1713,704,546 - 13,717,841 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01715,315,258 - 15,328,555 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01713,631,365 - 13,644,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01713,799,383 - 13,812,877 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1713,799,383 - 13,812,704 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01715,871,251 - 15,884,751 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,657,822 - 19,661,106 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1713,529,246 - 13,542,351 (-)NCBICelera
Cytogenetic Map17p14NCBI
S1PR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38988,990,863 - 89,005,155 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl988,990,863 - 89,005,155 (+)EnsemblGRCh38hg38GRCh38
GRCh37991,605,778 - 91,620,070 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36990,796,182 - 90,809,745 (+)NCBINCBI36Build 36hg18NCBI36
Build 34988,835,915 - 88,849,478NCBI
Celera962,189,011 - 62,202,574 (+)NCBICelera
Cytogenetic Map9q22.1NCBI
HuRef961,438,768 - 61,452,511 (+)NCBIHuRef
CHM1_1991,754,483 - 91,768,224 (+)NCBICHM1_1
T2T-CHM13v2.09101,153,351 - 101,167,644 (+)NCBIT2T-CHM13v2.0
S1pr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391351,562,654 - 51,576,833 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1351,562,675 - 51,576,833 (+)EnsemblGRCm39 Ensembl
GRCm381351,408,618 - 51,422,797 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1351,408,639 - 51,422,797 (+)EnsemblGRCm38mm10GRCm38
MGSCv371351,503,987 - 51,518,166 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361351,421,260 - 51,435,293 (+)NCBIMGSCv36mm8
Celera1352,481,303 - 52,495,482 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1326.12NCBI
S1pr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555153,024,258 - 3,035,996 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555153,024,258 - 3,035,996 (-)NCBIChiLan1.0ChiLan1.0
S1PR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21150,455,855 - 50,460,900 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1950,459,337 - 50,463,288 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0960,080,189 - 60,094,311 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1988,126,416 - 88,140,149 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl988,126,476 - 88,137,333 (+)Ensemblpanpan1.1panPan2
S1PR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1197,102,708 - 97,107,611 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl197,104,652 - 97,105,857 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha197,565,504 - 97,576,501 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0197,714,499 - 97,725,495 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl197,714,526 - 97,725,557 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1197,342,250 - 97,353,244 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0197,061,323 - 97,072,318 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0197,819,845 - 97,830,838 (-)NCBIUU_Cfam_GSD_1.0
S1pr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494410,793,383 - 10,849,904 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493764539,701 - 42,497 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493764539,690 - 40,790 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
S1PR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14659,309 - 671,706 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114659,314 - 674,969 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214880,158 - 898,709 (+)NCBISscrofa10.2Sscrofa10.2susScr3
S1PR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11299,484,615 - 99,498,211 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1299,494,423 - 99,495,559 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603887,806,079 - 87,819,666 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
S1pr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476523,659,973 - 23,673,809 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476523,660,155 - 23,673,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in S1pr3
105 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:37
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000019473
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17211514921881669Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)17429913021293263Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17429913021293263Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1581553Pur14Proteinuria QTL 145.30.0001urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)17797996816317111Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920136523653323Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920136523653323Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat

Markers in Region
RH132124  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21713,781,313 - 13,781,506 (+)MAPPERmRatBN7.2
Rnor_6.01713,799,647 - 13,799,839NCBIRnor6.0
Rnor_5.01715,871,515 - 15,871,707UniSTSRnor5.0
RGSC_v3.41719,658,086 - 19,658,278UniSTSRGSC3.4
Celera1713,529,510 - 13,529,702UniSTS
RH 3.4 Map17145.5UniSTS
Cytogenetic Map17p14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 25 2 2 11 2 37 26 29 11
Low 1 18 55 39 8 39 8 11 37 9 7 8
Below cutoff 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019473   ⟹   ENSRNOP00000019473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1713,781,050 - 13,794,505 (-)Ensembl
Rnor_6.0 Ensembl1713,799,383 - 13,812,615 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085581   ⟹   ENSRNOP00000074813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1713,799,384 - 13,812,704 (-)Ensembl
RefSeq Acc Id: NM_001271143   ⟹   NP_001258072
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81713,932,773 - 13,946,013 (-)NCBI
mRatBN7.21713,781,050 - 13,794,296 (-)NCBI
Rnor_6.01713,799,383 - 13,812,615 (-)NCBI
Rnor_5.01715,871,251 - 15,884,751 (-)NCBI
Celera1713,529,246 - 13,542,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006253680   ⟹   XP_006253742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81713,932,773 - 13,946,141 (-)NCBI
mRatBN7.21713,781,050 - 13,794,408 (-)NCBI
Rnor_6.01713,799,383 - 13,812,746 (-)NCBI
Rnor_5.01715,871,251 - 15,884,751 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063276353   ⟹   XP_063132423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81713,932,773 - 13,946,213 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001258072 (Get FASTA)   NCBI Sequence Viewer  
  XP_006253742 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132423 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD56238 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019473
  ENSRNOP00000019473.1
Reference Protein Sequences
RefSeq Acc Id: NP_001258072   ⟸   NM_001271143
- UniProtKB: F1M9D3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253742   ⟸   XM_006253680
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K910 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074813   ⟸   ENSRNOT00000085581
RefSeq Acc Id: ENSRNOP00000019473   ⟸   ENSRNOT00000019473
RefSeq Acc Id: XP_063132423   ⟸   XM_063276353
- Peptide Label: isoform X1
- UniProtKB: F1M9D3 (UniProtKB/TrEMBL)
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M9D3-F1-model_v2 AlphaFold F1M9D3 1-379 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700340
Promoter ID:EPDNEW_R10863
Type:multiple initiation site
Name:S1pr3_1
Description:sphingosine-1-phosphate receptor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01713,812,628 - 13,812,688EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1583843 AgrOrtholog
BioCyc Gene G2FUF-10069 BioCyc
Ensembl Genes ENSRNOG00000014524 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019473 ENTREZGENE
  ENSRNOT00000019473.4 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  EDG3_rcpt UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  S1P_rcpt UniProtKB/TrEMBL
KEGG Report rno:306792 UniProtKB/TrEMBL
NCBI Gene 306792 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  SPHINGOSINE 1-PHOSPHATE RECEPTOR 3 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PhenoGen S1pr3 PhenoGen
PRINTS EDG3RECEPTOR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
  S1PRECEPTOR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014524 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0G2K910 ENTREZGENE
  F1M9D3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-05-20 S1pr3  sphingosine-1-phosphate receptor 3  Edg3  endothelial differentiation, sphingolipid G-protein-coupled receptor, 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-12 Edg3  endothelial differentiation, sphingolipid G-protein-coupled receptor, 3  LOC306792  similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC306792  similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3)      Symbol and Name status set to provisional 70820 PROVISIONAL