S1PR3 (sphingosine-1-phosphate receptor 3) - Rat Genome Database

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Gene: S1PR3 (sphingosine-1-phosphate receptor 3) Chlorocebus sabaeus
Analyze
Symbol: S1PR3
Name: sphingosine-1-phosphate receptor 3
RGD ID: 18380773
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); integrin binding (inferred); sphingosine-1-phosphate receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); Notch signaling pathway (ortholog); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; FOUND IN presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sphingosine 1-phosphate receptor 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11299,484,615 - 99,498,211 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1299,494,423 - 99,495,559 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603887,806,079 - 87,819,666 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
S1PR3Green Monkeyadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway involved_inIEAUniProtKB:Q9Z0U9 and ensembl:ENSMUSP00000085293150520179 EnsemblGO_REF:0000107
S1PR3Green Monkeyadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway acts_upstream_of_or_withinISOS1pr3 (Mus musculus)9068941 PMID:11443127MGIPMID:11443127
S1PR3Green MonkeyG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 more ...150520179 InterProGO_REF:0000002
S1PR3Green MonkeyG protein-coupled receptor signaling pathway involved_inIEAARBA:ARBA00029021150520179 UniProtGO_REF:0000117
S1PR3Green MonkeyG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-0297150520179 UniProtGO_REF:0000043
S1PR3Green Monkeyinflammatory response involved_inIEAUniProtKB:Q9Z0U9 and ensembl:ENSMUSP00000085293150520179 EnsemblGO_REF:0000107
S1PR3Green Monkeyinflammatory response acts_upstream_of_or_withinISOMGI:21826379068941 PMID:18305483MGIPMID:18305483
S1PR3Green Monkeynegative regulation of establishment of endothelial barrier involved_inIEAUniProtKB:Q99500 and ensembl:ENSP00000350878150520179 EnsemblGO_REF:0000107
S1PR3Green MonkeyNotch signaling pathway acts_upstream_of_or_withinISOS1pr3 (Mus musculus)9068941 PMID:23117660MGIPMID:23117660
S1PR3Green MonkeyNotch signaling pathway involved_inIEAUniProtKB:Q9Z0U9 and ensembl:ENSMUSP00000085293150520179 EnsemblGO_REF:0000107
S1PR3Green Monkeyregulation of interleukin-1 beta production involved_inIEAUniProtKB:Q9Z0U9 and ensembl:ENSMUSP00000085293150520179 EnsemblGO_REF:0000107
S1PR3Green Monkeyregulation of interleukin-1 beta production acts_upstream_of_or_withinISOMGI:21826379068941 PMID:18305483MGIPMID:18305483
S1PR3Green Monkeysphingosine-1-phosphate receptor signaling pathway involved_inIEAGO:0038036150520179 GOCGO_REF:0000108
1 to 13 of 13 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
S1PR3Green Monkeymembrane located_inIEAInterPro:IPR000276 more ...150520179 InterProGO_REF:0000002
S1PR3Green Monkeyplasma membrane located_inIEAUniProtKB-KW:KW-1003150520179 UniProtGO_REF:0000043
S1PR3Green Monkeyplasma membrane located_inIEAUniProtKB-SubCell:SL-0039150520179 UniProtGO_REF:0000044
S1PR3Green Monkeyplasma membrane located_inIEAUniProtKB:Q99500 and ensembl:ENSP00000350878150520179 EnsemblGO_REF:0000107
S1PR3Green Monkeypresynapse located_inIEAUniProtKB:Q9Z0U9 and ensembl:ENSMUSP00000085293150520179 EnsemblGO_REF:0000107
S1PR3Green Monkeypresynapse is_active_inISOS1pr3 (Mus musculus)9068941 PMID:35781853SynGOPMID:35781853

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
S1PR3Green MonkeyG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-0297150520179 UniProtGO_REF:0000043
S1PR3Green Monkeyintegrin binding enablesIEAUniProtKB:Q99500 and ensembl:ENSP00000350878150520179 EnsemblGO_REF:0000107
S1PR3Green Monkeyprotein binding enablesISOUniProtKB:P161449068941 PMID:24851274IntActPMID:24851274
S1PR3Green Monkeyprotein binding enablesISOUniProtKB:P06028 and UniProtKB:P219649068941 PMID:32296183IntActPMID:32296183
S1PR3Green Monkeysphingosine-1-phosphate receptor activity enablesIEAInterPro:IPR004061 and InterPro:IPR004062150520179 InterProGO_REF:0000002

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
S1PR3Green Monkeysphingosine 1-phosphate signaling pathway  ISOS1PR3 (Homo sapiens)9068941 PIDPID:200046 and PID:200123
PMID:22301074  



S1PR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11299,484,615 - 99,498,211 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1299,494,423 - 99,495,559 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603887,806,079 - 87,819,666 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
S1PR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38988,990,863 - 89,005,155 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl988,990,863 - 89,005,155 (+)EnsemblGRCh38hg38GRCh38
GRCh37991,605,778 - 91,620,070 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36990,796,182 - 90,809,745 (+)NCBINCBI36Build 36hg18NCBI36
Build 34988,835,915 - 88,849,478NCBI
Celera962,189,011 - 62,202,574 (+)NCBICelera
Cytogenetic Map9q22.1NCBI
HuRef961,438,768 - 61,452,511 (+)NCBIHuRef
CHM1_1991,754,483 - 91,768,224 (+)NCBICHM1_1
T2T-CHM13v2.09101,153,351 - 101,167,644 (+)NCBIT2T-CHM13v2.0
S1pr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391351,562,654 - 51,576,833 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1351,562,675 - 51,576,833 (+)EnsemblGRCm39 Ensembl
GRCm381351,408,618 - 51,422,797 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1351,408,639 - 51,422,797 (+)EnsemblGRCm38mm10GRCm38
MGSCv371351,503,987 - 51,518,166 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361351,421,260 - 51,435,293 (+)NCBIMGSCv36mm8
Celera1352,481,303 - 52,495,482 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1326.12NCBI
S1pr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81713,932,773 - 13,946,213 (-)NCBIGRCr8
mRatBN7.21713,781,050 - 13,794,408 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1713,781,050 - 13,794,505 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1713,704,546 - 13,717,841 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01715,315,258 - 15,328,555 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01713,631,365 - 13,644,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01713,799,383 - 13,812,877 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1713,799,383 - 13,812,704 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01715,871,251 - 15,884,751 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,657,822 - 19,661,106 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1713,529,246 - 13,542,351 (-)NCBICelera
Cytogenetic Map17p14NCBI
S1pr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555153,024,258 - 3,035,996 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555153,024,258 - 3,035,996 (-)NCBIChiLan1.0ChiLan1.0
S1PR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21150,455,855 - 50,460,900 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1950,459,337 - 50,463,288 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0960,080,189 - 60,094,311 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1988,126,416 - 88,140,149 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl988,126,476 - 88,137,333 (+)Ensemblpanpan1.1panPan2
S1PR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1197,102,708 - 97,107,611 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl197,104,652 - 97,105,857 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha197,565,504 - 97,576,501 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0197,714,499 - 97,725,495 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl197,714,526 - 97,725,557 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1197,342,250 - 97,353,244 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0197,061,323 - 97,072,318 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0197,819,845 - 97,830,838 (-)NCBIUU_Cfam_GSD_1.0
S1pr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494410,793,383 - 10,849,904 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493764539,701 - 42,497 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493764539,690 - 40,790 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
S1PR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14659,309 - 671,706 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114659,314 - 674,969 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214880,158 - 898,709 (+)NCBISscrofa10.2Sscrofa10.2susScr3
S1pr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476523,659,973 - 23,673,809 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476523,660,155 - 23,673,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in S1PR3
312 total Variants



ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 17 33 33 60 20


RefSeq Transcripts XM_007969698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000018597   ⟹   ENSCSAP00000018046
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1299,494,423 - 99,495,559 (+)Ensembl
RefSeq Acc Id: XM_007969698   ⟹   XP_007967889
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11299,484,615 - 99,498,211 (+)NCBI
Vero_WHO_p1.0NW_02366603887,806,079 - 87,819,666 (+)NCBI
Sequence:
Protein RefSeqs XP_007967889 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018046.1
RefSeq Acc Id: XP_007967889   ⟸   XM_007969698
Ensembl Acc Id: ENSCSAP00000018046   ⟸   ENSCSAT00000018597



1 to 20 of 20 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCSAG00000018507 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000018597.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro EDG3_rcpt UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  S1P_rcpt UniProtKB/TrEMBL
KEGG Report csab:103219719 UniProtKB/TrEMBL
NCBI Gene S1PR3 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  SPHINGOSINE 1-PHOSPHATE RECEPTOR 3 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS EDG3RECEPTOR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
  S1PRECEPTOR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0D9SB07_CHLSB UniProtKB/TrEMBL
1 to 20 of 20 rows