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Gene: S1pr3 (sphingosine-1-phosphate receptor 3) Mus musculus
Symbol: S1pr3
Name: sphingosine-1-phosphate receptor 3
Description: Predicted to have G protein-coupled receptor activity and integrin binding activity. Involved in several processes, including Notch signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and regulation of interleukin-1 beta production. Predicted to localize to cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and limb. Orthologous to human S1PR3 (sphingosine-1-phosphate receptor 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI132464; Edg3; endothelial differentiation G-protein coupled receptor 3; endothelial differentiation sphingolipid G-protein-coupled receptor 3; Lpb3; lysophospholipid receptor B3; S1p receptor 3; S1P receptor Edg-3; S1p3; sphingosine 1-phosphate receptor 3; sphingosine 1-phosphate receptor Edg-3
Homo sapiens (human) : S1PR3 (sphingosine-1-phosphate receptor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : S1pr3 (sphingosine-1-phosphate receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : S1pr3 (sphingosine-1-phosphate receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : S1PR3 (sphingosine-1-phosphate receptor 3)
Canis lupus familiaris (dog) : S1PR3 (sphingosine-1-phosphate receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S1pr3 (sphingosine-1-phosphate receptor 3)
Sus scrofa (pig) : S1PR3 (sphingosine-1-phosphate receptor 3)
Chlorocebus sabaeus (African green monkey) : S1PR3 (sphingosine-1-phosphate receptor 3)
Heterocephalus glaber (naked mole-rat) : S1pr3 (sphingosine-1-phosphate receptor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1351,408,639 - 51,422,797 (+)EnsemblGRCm38mm10GRCm38
GRCm381351,408,618 - 51,422,797 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371351,503,987 - 51,518,166 (+)NCBIGRCm37mm9NCBIm37
MGSCv361351,421,260 - 51,435,293 (+)NCBImm8
Celera1352,481,303 - 52,495,482 (+)NCBICelera
Cytogenetic Map13A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on S1pr3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62254
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.