Tigar (TP53 induced glycolysis regulatory phosphatase) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Tigar (TP53 induced glycolysis regulatory phosphatase) Rattus norvegicus
Analyze
Symbol: Tigar
Name: TP53 induced glycolysis regulatory phosphatase
RGD ID: 1560038
Description: Predicted to enable fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in several processes, including cellular response to cobalt ion; regulation of phosphate metabolic process; and response to ischemia. Predicted to act upstream of or within several processes, including fructose 2,6-bisphosphate metabolic process; negative regulation of metabolic process; and positive regulation of cardiac muscle cell apoptotic process. Predicted to be located in mitochondrial outer membrane and nucleus. Predicted to be active in cytosol. Orthologous to human TIGAR (TP53 induced glycolysis regulatory phosphatase); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fructose-2,6-bisphosphatase TIGAR; hypothetical protein LOC502894; LOC502894; TP53-induced glycolysis and apoptosis regulator; uncharacterized protein LOC502894
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Tigar-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84161,613,306 - 161,632,248 (-)NCBIGRCr8
mRatBN7.24159,927,136 - 159,946,077 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl687,509,809 - 87,510,466 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl4159,927,139 - 159,946,029 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4166,156,946 - 166,175,860 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04161,939,848 - 161,958,766 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04160,573,896 - 160,592,815 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04159,635,145 - 159,654,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4159,635,153 - 159,654,063 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04231,948,786 - 231,966,869 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44163,481,393 - 163,502,412 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4148,642,195 - 148,661,115 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TigarRatepisodic ataxia type 1  ISOTIGAR (Homo sapiens)8554872ClinVar Annotator: match by term: Episodic ataxia type 1ClinVarPMID:28492532
TigarRatHyperphosphatemic Familial Tumoral Calcinosis 1  ISOTIGAR (Homo sapiens)8554872ClinVar Annotator: match by term: Tumoral calcinosis more ...ClinVarPMID:25378588 and PMID:29389098
TigarRatlymphoproliferative syndrome 2  ISOTIGAR (Homo sapiens)8554872ClinVar Annotator: match by term: Lymphoproliferative syndrome 2ClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TigarRatNerve Degeneration  ISOTIGAR (Homo sapiens)11554173CTD Direct Evidence: therapeuticCTDPMID:33359019

1 to 20 of 115 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TigarRat(-)-demecolcine increases expressionISOTIGAR (Homo sapiens)6480464Demecolcine results in increased expression of TIGAR mRNACTDPMID:23649840
TigarRat(S)-colchicine decreases expressionISOTIGAR (Homo sapiens)6480464Colchicine results in decreased expression of TIGAR mRNACTDPMID:24211769
TigarRat1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactionsISOTigar (Mus musculus)6480464NADP inhibits the reaction [TIGAR protein affects the reaction [1-Methyl-4-phenyl-1 more ...CTDPMID:33359019
TigarRat1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expressionISOTigar (Mus musculus)64804641-Methyl-4-phenyl-1 more ...CTDPMID:33359019
TigarRat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of TIGAR mRNACTDPMID:32145629
TigarRat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOTIGAR (Homo sapiens)64804642 more ...CTDPMID:31675489
TigarRat2,4,6-tribromophenol increases expressionISOTIGAR (Homo sapiens)64804642 more ...CTDPMID:31675489
TigarRat3,3',5,5'-tetrabromobisphenol A increases expressionISOTIGAR (Homo sapiens)6480464tetrabromobisphenol A results in increased expression of TIGAR proteinCTDPMID:31675489
TigarRat4,4'-sulfonyldiphenol increases expressionISOTigar (Mus musculus)6480464bisphenol S results in increased expression of TIGAR mRNACTDPMID:39298647
TigarRat5-fluorouracil multiple interactionsISOTIGAR (Homo sapiens)6480464TP53 protein affects the reaction [Fluorouracil results in increased expression of TIGAR mRNA]CTDPMID:15016801
TigarRat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of TIGAR mRNACTDPMID:25825206
TigarRatacetamide increases expressionEXP 6480464acetamide results in increased expression of TIGAR mRNACTDPMID:31881176
TigarRatactinomycin D multiple interactionsISOTIGAR (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased expression of TIGAR proteinCTDPMID:38460933
TigarRatadefovir pivoxil increases expressionISOTIGAR (Homo sapiens)6480464adefovir dipivoxil results in increased expression of TIGAR mRNACTDPMID:25596134
TigarRatadenine decreases expressionISOTIGAR (Homo sapiens)6480464Adenine results in decreased expression of TIGAR mRNACTDPMID:24211769
TigarRataflatoxin B1 affects expressionISOTIGAR (Homo sapiens)6480464Aflatoxin B1 affects the expression of TIGAR proteinCTDPMID:20106945
TigarRataflatoxin B1 increases expressionISOTIGAR (Homo sapiens)6480464Aflatoxin B1 results in increased expression of TIGAR mRNACTDPMID:21632981 more ...
TigarRatantirheumatic drug decreases expressionISOTIGAR (Homo sapiens)6480464Antirheumatic Agents results in decreased expression of TIGAR mRNACTDPMID:24449571
TigarRataristolochic acid A increases expressionISOTIGAR (Homo sapiens)6480464aristolochic acid I results in increased expression of TIGAR proteinCTDPMID:33212167
TigarRatarsane multiple interactionsISOTIGAR (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of TIGAR mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TIGAR mRNACTDPMID:39836092

1 to 20 of 115 rows

Biological Process
1 to 20 of 49 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TigarRatcardiac muscle cell apoptotic process acts_upstream_ofISOTigar (Mus musculus)1624291MGI:5319187 PMID:22044588RGDPMID:22044588
TigarRatcardiac muscle cell apoptotic process acts_upstream_ofIEAUniProtKB:Q8BZA9 and ensembl:ENSMUSP000000486431600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatcellular response to cobalt ion involved_inISOTIGAR (Homo sapiens)1624291 PMID:25928429RGDPMID:25928429
TigarRatcellular response to cobalt ion involved_inIEAUniProtKB:Q9NQ88 and ensembl:ENSP000001792591600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatcellular response to hypoxia involved_inISOTIGAR (Homo sapiens)1624291 PMID:23185017RGDPMID:23185017
TigarRatcellular response to hypoxia involved_inIEAUniProtKB:Q9NQ88 and ensembl:ENSP000001792591600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatDNA damage response involved_inISOTIGAR (Homo sapiens)1624291 PMID:25928429RGDPMID:25928429
TigarRatDNA damage response involved_inIEAUniProtKB:Q9NQ88 and ensembl:ENSP000001792591600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatfructose 2,6-bisphosphate metabolic process acts_upstream_of_or_withinISOTigar (Mus musculus)1624291 PMID:20935145RGDPMID:20935145
TigarRatfructose 2,6-bisphosphate metabolic process acts_upstream_of_or_withinIEAUniProtKB:Q8BZA9 and ensembl:ENSMUSP000000486431600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatglucose catabolic process to lactate via pyruvate acts_upstream_ofISOTigar (Mus musculus)1624291 PMID:20935145RGDPMID:20935145
TigarRatglucose catabolic process to lactate via pyruvate acts_upstream_ofIEAUniProtKB:Q8BZA9 and ensembl:ENSMUSP000000486431600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatglycolytic process acts_upstream_ofIEAUniProtKB:Q8BZA9 and ensembl:ENSMUSP000000486431600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatglycolytic process acts_upstream_ofISOTigar (Mus musculus)1624291 PMID:20935145RGDPMID:20935145
TigarRatintestinal epithelial cell development acts_upstream_of_or_withinISOTigar (Mus musculus)1624291MGI:4391656 PMID:23726973RGDPMID:23726973
TigarRatintestinal epithelial cell development acts_upstream_of_or_withinIEAUniProtKB:Q8BZA9 and ensembl:ENSMUSP000000486431600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatmitophagy acts_upstream_ofIEAUniProtKB:Q8BZA9 and ensembl:ENSMUSP000000486431600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatmitophagy acts_upstream_ofISOTigar (Mus musculus)1624291MGI:5319187 PMID:22044588RGDPMID:22044588
TigarRatnegative regulation of glucose catabolic process to lactate via pyruvate acts_upstream_of_or_withinIEAUniProtKB:Q8BZA9 and ensembl:ENSMUSP000000486431600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatnegative regulation of glucose catabolic process to lactate via pyruvate acts_upstream_of_or_withinISOTigar (Mus musculus)1624291 PMID:20935145RGDPMID:20935145
1 to 20 of 49 rows

Cellular Component
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TigarRatcytoplasm located_inISOTIGAR (Homo sapiens)1624291 PMID:23185017 and PMID:25928429RGDPMID:23185017 and PMID:25928429
TigarRatcytoplasm located_inIEAUniProtKB:Q9NQ88 and ensembl:ENSP000001792591600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatcytoplasm located_inIEAUniProtKB:Q8BZA9 and ensembl:ENSMUSP000000486431600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatcytoplasm located_inISOTigar (Mus musculus)1624291 PMID:24872551RGDPMID:24872551
TigarRatcytosol is_active_inIBAPANTHER:PTN002926186 and UniProtKB:Q9NQ881600115GO_REF:0000033GO_CentralGO_REF:0000033
TigarRatcytosol located_inIEAUniProtKB:Q9NQ88 and ensembl:ENSP000001792591600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatcytosol located_inISOTIGAR (Homo sapiens)1624291 RGDGO_REF:0000052
TigarRatmitochondrial outer membrane located_inISOTIGAR (Homo sapiens)1624291 PMID:23185017RGDPMID:23185017
TigarRatmitochondrial outer membrane located_inIEAUniProtKB:Q9NQ88 and ensembl:ENSP000001792591600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatmitochondrion located_inISOTigar (Mus musculus)1624291 PMID:24872551RGDPMID:24872551
TigarRatmitochondrion located_inIEAUniProtKB:Q8BZA9 and ensembl:ENSMUSP000000486431600115GO_REF:0000107EnsemblGO_REF:0000107
TigarRatnucleus located_inISOTIGAR (Homo sapiens)1624291 PMID:25928429RGDPMID:25928429
TigarRatnucleus located_inIEAUniProtKB:Q9NQ88 and ensembl:ENSP000001792591600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 13 of 13 rows

Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:16839880   PMID:19015259   PMID:20935145   PMID:22044588   PMID:23185017   PMID:23726973   PMID:24872551   PMID:25928429   PMID:31160088   PMID:31317559   PMID:33858654  



Tigar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84161,613,306 - 161,632,248 (-)NCBIGRCr8
mRatBN7.24159,927,136 - 159,946,077 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl687,509,809 - 87,510,466 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl4159,927,139 - 159,946,029 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4166,156,946 - 166,175,860 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04161,939,848 - 161,958,766 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04160,573,896 - 160,592,815 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04159,635,145 - 159,654,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4159,635,153 - 159,654,063 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04231,948,786 - 231,966,869 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44163,481,393 - 163,502,412 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4148,642,195 - 148,661,115 (-)NCBICelera
Cytogenetic Map4q42NCBI
TIGAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38124,321,213 - 4,360,028 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl124,307,763 - 4,360,028 (+)EnsemblGRCh38hg38GRCh38
GRCh37124,430,379 - 4,469,194 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,300,620 - 4,339,455 (+)NCBINCBI36Build 36hg18NCBI36
Build 34124,300,631 - 4,332,599NCBI
Celera126,052,425 - 6,091,264 (+)NCBICelera
Cytogenetic Map12p13.32NCBI
HuRef124,287,018 - 4,325,825 (+)NCBIHuRef
CHM1_1124,429,992 - 4,468,805 (+)NCBICHM1_1
T2T-CHM13v2.0124,327,996 - 4,366,805 (+)NCBIT2T-CHM13v2.0
Tigar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396127,062,079 - 127,086,564 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6127,062,079 - 127,086,520 (-)EnsemblGRCm39 Ensembl
GRCm386127,085,116 - 127,109,552 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6127,085,116 - 127,109,557 (-)EnsemblGRCm38mm10GRCm38
MGSCv376127,035,134 - 127,059,570 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366127,052,982 - 127,075,160 (-)NCBIMGSCv36mm8
MGSCv366127,984,031 - 128,005,972 (-)NCBIMGSCv36mm8
Celera6128,766,834 - 128,786,116 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map661.92NCBI
Tigar
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554132,129,678 - 2,154,380 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554132,129,719 - 2,153,873 (+)NCBIChiLan1.0ChiLan1.0
TIGAR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2109,860,833 - 9,893,058 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1129,857,630 - 9,896,658 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0124,429,945 - 4,462,142 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1124,353,272 - 4,386,758 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl124,353,272 - 4,385,380 (+)Ensemblpanpan1.1panPan2
TIGAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12740,521,751 - 40,549,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2740,523,314 - 40,549,332 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha276,132,902 - 6,160,282 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02740,877,557 - 40,905,336 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2740,877,558 - 40,905,335 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12740,815,806 - 40,843,030 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02740,791,244 - 40,818,291 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0275,543,778 - 5,570,944 (+)NCBIUU_Cfam_GSD_1.0
Tigar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945104,632,126 - 104,665,630 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366064,518,584 - 4,540,114 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366064,518,525 - 4,540,109 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIGAR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl566,044,686 - 66,067,377 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1566,044,679 - 66,067,571 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2568,266,609 - 68,289,947 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TIGAR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1114,354,911 - 4,381,762 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl114,355,053 - 4,381,273 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660633,861,799 - 3,888,740 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tigar
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248601,417,131 - 1,457,717 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248601,416,419 - 1,455,953 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Tigar
50 total Variants

1 to 10 of 35 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat

1 to 10 of 35 rows
D4Mit25  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24159,940,316 - 159,940,457 (+)MAPPERmRatBN7.2
Rnor_6.04159,648,325 - 159,648,465NCBIRnor6.0
Rnor_5.04231,953,550 - 231,953,690UniSTSRnor5.0
RGSC_v3.44163,495,153 - 163,495,293UniSTSRGSC3.4
RGSC_v3.44163,495,152 - 163,495,293RGDRGSC3.4
RGSC_v3.14163,740,089 - 163,740,229RGD
Celera4148,655,370 - 148,655,510UniSTS
RH 3.4 Map41003.6RGD
RH 3.4 Map41003.6UniSTS
Cytogenetic Map4q42UniSTS
D4Got310  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr84161,626,889 - 161,627,079 (+)Marker Load Pipeline
mRatBN7.24159,940,720 - 159,940,910 (+)MAPPERmRatBN7.2
Rnor_6.04159,648,729 - 159,648,916NCBIRnor6.0
Rnor_5.04231,953,099 - 231,953,286UniSTSRnor5.0
RGSC_v3.44163,495,557 - 163,496,365UniSTSRGSC3.4
RGSC_v3.44163,495,557 - 163,495,744UniSTSRGSC3.4
Celera4148,655,774 - 148,655,961UniSTS
Cytogenetic Map4q42UniSTS
RH128614  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24159,927,286 - 159,927,487 (+)MAPPERmRatBN7.2
Rnor_6.04159,635,296 - 159,635,496NCBIRnor6.0
Rnor_5.04231,966,518 - 231,966,718UniSTSRnor5.0
RGSC_v3.44163,481,539 - 163,481,739UniSTSRGSC3.4
Celera4148,642,341 - 148,642,541UniSTS
RH 3.4 Map41009.1UniSTS
Cytogenetic Map4q42UniSTS
BF386144  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24159,928,629 - 159,928,796 (-)MAPPERmRatBN7.2
mRatBN7.24159,928,629 - 159,928,796 (+)MAPPERmRatBN7.2
mRatBN7.2687,510,667 - 87,510,834 (-)MAPPERmRatBN7.2
mRatBN7.2687,510,667 - 87,510,834 (+)MAPPERmRatBN7.2
Rnor_6.0691,332,590 - 91,332,756NCBIRnor6.0
Rnor_6.04159,636,639 - 159,636,805NCBIRnor6.0
Rnor_5.04231,965,209 - 231,965,375UniSTSRnor5.0
Rnor_5.06100,794,516 - 100,794,682UniSTSRnor5.0
RGSC_v3.44163,482,882 - 163,483,048UniSTSRGSC3.4
RGSC_v3.4691,001,278 - 91,001,444UniSTSRGSC3.4
Celera686,015,520 - 86,015,686UniSTS
Celera4148,643,684 - 148,643,850UniSTS
RH 3.4 Map6549.8UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map6q24UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000091662   ⟹   ENSRNOP00000074722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4159,927,144 - 159,946,025 (-)Ensembl
Rnor_6.0 Ensembl4159,635,153 - 159,654,063 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098356   ⟹   ENSRNOP00000088153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4159,927,143 - 159,946,029 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111057   ⟹   ENSRNOP00000092807
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4159,927,139 - 159,945,993 (-)Ensembl
RefSeq Acc Id: NM_001025064   ⟹   NP_001020235
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,613,306 - 161,632,229 (-)NCBI
mRatBN7.24159,927,136 - 159,946,061 (-)NCBI
Rnor_6.04159,635,150 - 159,654,063 (-)NCBI
Rnor_5.04231,948,786 - 231,966,869 (+)NCBI
RGSC_v3.44163,481,393 - 163,502,412 (-)RGD
Celera4148,642,195 - 148,661,115 (-)RGD
Sequence:
RefSeq Acc Id: NM_001395051   ⟹   NP_001381980
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,613,306 - 161,632,229 (-)NCBI
mRatBN7.24159,927,136 - 159,946,061 (-)NCBI
RefSeq Acc Id: XM_039108258   ⟹   XP_038964186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,613,311 - 161,632,248 (-)NCBI
mRatBN7.24159,927,138 - 159,946,077 (-)NCBI
1 to 11 of 11 rows
Protein RefSeqs NP_001020235 (Get FASTA)   NCBI Sequence Viewer  
  NP_001381980 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964186 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH93610 (Get FASTA)   NCBI Sequence Viewer  
  EDM01816 (Get FASTA)   NCBI Sequence Viewer  
  EDM01817 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074722
  ENSRNOP00000074722.2
  ENSRNOP00000085702.1
  ENSRNOP00000088153.1
  ENSRNOP00000092807.1
1 to 11 of 11 rows
RefSeq Acc Id: NP_001020235   ⟸   NM_001025064
- Peptide Label: isoform 2
- UniProtKB: Q566D2 (UniProtKB/TrEMBL),   A0A8I6A442 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074722   ⟸   ENSRNOT00000091662
RefSeq Acc Id: XP_038964186   ⟸   XM_039108258
- Peptide Label: isoform X1
- UniProtKB: Q566D2 (UniProtKB/TrEMBL),   A0A8I6A442 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000088153   ⟸   ENSRNOT00000098356
Ensembl Acc Id: ENSRNOP00000092807   ⟸   ENSRNOT00000111057

Name Modeler Protein Id AA Range Protein Structure
AF-Q566D2-F1-model_v2 AlphaFold Q566D2 1-178 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693420
Promoter ID:EPDNEW_R3945
Type:initiation region
Name:Tigar_1
Description:TP53 induced glycolysis regulatory phosphatase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04159,654,056 - 159,654,116EPDNEW


1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-42949 BioCyc
BioCyc Pathway PWY66-423 [fructose 2,6-bisphosphate biosynthesis] BioCyc
BioCyc Pathway Image PWY66-423 BioCyc
Ensembl Genes ENSRNOG00000046064 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000051816 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000071048.2 UniProtKB/TrEMBL
  ENSRNOT00000091662 ENTREZGENE
  ENSRNOT00000091662.2 UniProtKB/TrEMBL
  ENSRNOT00000098356.1 UniProtKB/TrEMBL
  ENSRNOT00000111057.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1240 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7319640 IMAGE-MGC_LOAD
InterPro His_Pase_superF_clade-1 UniProtKB/TrEMBL
  His_PPase_superfam UniProtKB/TrEMBL
  PG/BPGM_mutase_AS UniProtKB/TrEMBL
  Phosphoglycerate_Mutase UniProtKB/TrEMBL
KEGG Report rno:502894 UniProtKB/TrEMBL
MGC_CLONE MGC:105772 IMAGE-MGC_LOAD
NCBI Gene 502894 ENTREZGENE
PANTHER FRUCTOSE-2,6-BISPHOSPHATASE TIGAR UniProtKB/TrEMBL
  FRUCTOSE-2,6-BISPHOSPHATASE TIGAR UniProtKB/TrEMBL
Pfam His_Phos_1 UniProtKB/TrEMBL
PhenoGen Tigar PhenoGen
PROSITE PG_MUTASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046064 RatGTEx
  ENSRNOG00000051816 RatGTEx
SMART PGAM UniProtKB/TrEMBL
Superfamily-SCOP SSF53254 UniProtKB/TrEMBL
UniProt A0A0G2K8S8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A442 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A9E3_RAT UniProtKB/TrEMBL
  A0A8I6AIY8 ENTREZGENE, UniProtKB/TrEMBL
  A6ILX2 ENTREZGENE, UniProtKB/TrEMBL
  Q566D2 ENTREZGENE, UniProtKB/TrEMBL
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-17 Tigar  TP53 induced glycolysis regulatory phosphatase  LOC502894  hypothetical protein LOC502894  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC502894  hypothetical protein LOC502894      Symbol and Name status set to provisional 70820 PROVISIONAL