Tigar (TP53 induced glycolysis regulatory phosphatase)

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Gene: Tigar (TP53 induced glycolysis regulatory phosphatase) Chinchilla lanigera

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Symbol:

Tigar

Name:

TP53 induced glycolysis regulatory phosphatase

RGD ID:

8858319

Description:

ENCODES a protein that exhibits fructose-2,6-bisphosphate 2-phosphatase activity (ortholog); INVOLVED IN cardiac muscle cell apoptotic process (ortholog); cellular response to cobalt ion (ortholog); cellular response to hypoxia (ortholog); ASSOCIATED WITH episodic ataxia type 1 (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); lymphoproliferative syndrome 2 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial outer membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

fructose-2,6-bisphosphatase TIGAR

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	2,129,678 - 2,154,380 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	2,129,719 - 2,153,873 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

episodic ataxia type 1 (ISO)

Hyperphosphatemic Familial Tumoral Calcinosis 1 (ISO)

lymphoproliferative syndrome 2 (ISO)

Nerve Degeneration (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cardiac muscle cell apoptotic process (ISO)

cellular response to cobalt ion (ISO)

cellular response to hypoxia (ISO)

DNA damage response (ISO)

fructose 2,6-bisphosphate metabolic process (ISO)

glucose catabolic process to lactate via pyruvate (ISO)

glycolytic process (ISO)

intestinal epithelial cell development (ISO)

mitophagy (ISO)

negative regulation of glucose catabolic process to lactate via pyruvate (ISO)

negative regulation of glycolytic process (ISO)

negative regulation of mitophagy (ISO)

negative regulation of programmed cell death (ISO)

negative regulation of reactive oxygen species metabolic process (ISO)

positive regulation of cardiac muscle cell apoptotic process (ISO)

positive regulation of DNA repair (ISO)

positive regulation of hexokinase activity (ISO)

positive regulation of pentose-phosphate shunt (ISO)

reactive oxygen species metabolic process (ISO)

regulation of pentose-phosphate shunt (ISO)

regulation of response to DNA damage checkpoint signaling (ISO)

response to gamma radiation (ISO)

response to ischemia (ISO)

response to xenobiotic stimulus (ISO)

Cellular Component

cytoplasm (ISO)

cytosol (ISO)

mitochondrial outer membrane (ISO)

mitochondrion (ISO)

nucleus (ISO)

Molecular Function

fructose-2,6-bisphosphate 2-phosphatase activity (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Tigar
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	2,129,678 - 2,154,380 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	2,129,719 - 2,153,873 (+)	NCBI	ChiLan1.0	ChiLan1.0

TIGAR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	4,321,213 - 4,360,028 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	4,307,763 - 4,360,028 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	4,430,379 - 4,469,194 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	4,300,620 - 4,339,455 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	4,300,631 - 4,332,599	NCBI
Celera	12	6,052,425 - 6,091,264 (+)	NCBI		Celera
Cytogenetic Map	12	p13.32	NCBI
HuRef	12	4,287,018 - 4,325,825 (+)	NCBI		HuRef
CHM1_1	12	4,429,992 - 4,468,805 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	4,327,996 - 4,366,805 (+)	NCBI		T2T-CHM13v2.0

Tigar
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	127,062,079 - 127,086,564 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	127,062,079 - 127,086,520 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	127,085,116 - 127,109,552 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	127,085,116 - 127,109,557 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	127,035,134 - 127,059,570 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	127,052,982 - 127,075,160 (-)	NCBI		MGSCv36	mm8
MGSCv36	6	127,984,031 - 128,005,972 (-)	NCBI		MGSCv36	mm8
Celera	6	128,766,834 - 128,786,116 (-)	NCBI		Celera
Cytogenetic Map	6	F3	NCBI
cM Map	6	61.92	NCBI

Tigar
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	161,613,306 - 161,632,248 (-)	NCBI		GRCr8
mRatBN7.2	4	159,927,136 - 159,946,077 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	159,927,139 - 159,946,029 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	166,156,946 - 166,175,860 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	161,939,848 - 161,958,766 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	160,573,896 - 160,592,815 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	159,635,145 - 159,654,108 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	159,635,153 - 159,654,063 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	231,948,786 - 231,966,869 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	163,481,393 - 163,502,412 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	148,642,195 - 148,661,115 (-)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

TIGAR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	9,860,833 - 9,893,058 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	9,857,630 - 9,896,658 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	4,429,945 - 4,462,142 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	4,353,272 - 4,386,758 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	4,353,272 - 4,385,380 (+)	Ensembl	panpan1.1		panPan2

TIGAR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	40,521,751 - 40,549,304 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	40,523,314 - 40,549,332 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	6,132,902 - 6,160,282 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	40,877,557 - 40,905,336 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	40,877,558 - 40,905,335 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	40,815,806 - 40,843,030 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	40,791,244 - 40,818,291 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	5,543,778 - 5,570,944 (+)	NCBI		UU_Cfam_GSD_1.0

Tigar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	104,632,126 - 104,665,630 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936606	4,518,584 - 4,540,114 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936606	4,518,525 - 4,540,109 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TIGAR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	66,044,686 - 66,067,377 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	66,044,679 - 66,067,571 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	68,266,609 - 68,289,947 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TIGAR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	4,354,911 - 4,381,762 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	4,355,053 - 4,381,273 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	3,861,799 - 3,888,740 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tigar
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624860	1,417,131 - 1,457,717 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624860	1,416,419 - 1,455,953 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005378727	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005378728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01013540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01013541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01122114	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000019307 ⟹ ENSCLAP00000019122

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955413	2,129,678 - 2,154,380 (+)	Ensembl

RefSeq Acc Id:

XM_005378727 ⟹ XP_005378784

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955413	2,129,994 - 2,153,873 (+)	NCBI

Sequence:

show sequence

GTCACGCCAGATCCGTGCCCCTCTCTGCTGCCCGCAGATCTCCAAGTGTGAGGAGTTGCTCCTC
GTCGGCGGAGGTTGCGGCTCCTAGCTGCGTGGCGCTGCCCTCCCTTGACGCTCTCCTTGATTCT
CCCCTGTGCGCTCAGGGCCCACTTTTGAGGTCTATTTCCTCGCCTTCCAGAAAAGAATGCAGTT
CTGAGAGGGCAGGGAGGGCCGCAGCTTCCTCTCGGCTCACCGAGTGCTTCTAGCAGAACAGAAT
GCTGCAGCTAAGTCTGTCTCCACGTCCCCCGGCCTGCTGCCTCCTCAGTGGAGAAACGAGACTT
AACAAGGAGAAAATACTTCAAGGACAAGGCGTGGACGAGCCCCTTTCCGAGACTGGGTTCAAAC
AGGCGGCTGCGGCGGGGAGTTTTCTGAAAAATGTGCTGTTCACACACGCGTTTTCCAGCGACCT
CACCAGGACGAGGCAGACCACCCATGAGATTTTGGAGAAAAGCAAATTTTGCAAAGACATGACA
GTAAAGTATGATTCAAGACTTCGCGAAAGGAGGTACGGGGCTGCTGAAGGCAAGGCGCTGAGCG
AGCTGCGGGCCATGGCCAAGGCTGCGGGGATGGAGTGCCCGGTGTTCACGCCTCCCGGAGGAGA
GACGCTGGAGCAGGTAAAAACGCGTGGAAAAGATTTCTTTGAATTTCTTTGTCAACTAATCCTA
AAAGAAGCAGGTCAGAATGAACAGCTTTCCCCAGAAGTCCCAGTCAACTATCTGGAAACTTCTT
TGGCGGAGATATTTCCTTTAGGAGAAAACTGCAGTCCCGAGTGCTGTGTGGACCGCGGCCATCC
AGGACTGGCAGCCAGCATCTTGGTGGTGAGCCACGGGGCCTACATGAGGAGCCTTTTCAGCTAT
TTTCTGACCGACCTGAAGGGCTCCTTGCCAGCACTTCTGAACAGATCGGAACTTCTGTCTGTCA
GCCCCAACACTGGGATCAGCCTCTTCATCATAGACCTCGAAGAGGGTCGGGAACCCGAGGTCCA
CTGCGTCTGCATGAACCTGCAGGATCACCTGAACGGAGTCAACTGAAGGCGCCGAGTTCCAGCG
GTGTTAGAATCTGAGCAATTTGAGGGTCTGTAGGGAGCACCTTTGGCTTGCTTCAGTTCTGTCC
TTTGCTGTGGTGATTTGGAAACAATGAAAAATCAGCTTGTAAACCTCTATCCCAAACAATGATG
GAAAGCCATTTTGCACTGATTTAATTTTTACAAGCGCTGTTTGCATTTTCCAGAGTAATTTTGC
TGCCCTACTCAGTCACATCTCCATATTGAAAATGGGCAGAGGAACTGAGCATTGCAGTTGGGTA
TTAATCACCTTTTACTGTGTCTTCCCTGTTTTAAAATGTTGATGTATTTTTTTAATGCTCAGCT
TATATTATTGGCTCCTGCTAAAATACTGTATGCTTTTTGCATCTCATCTGGTGCTTCAGTGAAG
GAGCTCCCTGTAAATGACACTGCATATTTGTAGCAACTGTGTTATATTTAAAAAGGAAATATTC
TTTAAAGGAAATAGTGTCCCCATTATAAGTTCATGTAAAGTAAAATGATAAGAGAACACTAAAT
GTTGTATGTAGAAACCAGCCGTTGGAATATTTATTTTTATTCTAGAGGGCCCAGGTGTGGATGA
GGATACACTGTGACTGCAGAAAGGCGCAGAGAGAGGTTGGGCACCATGCGGTTAGAATACCTTA
CTGAAAGTAATGGAGCTTGTTCAGGATACCTTGCAAAAGCTGCCAGTGAGAACCGGGAAAATAA
ACAAAAACACACAAAAAACCCAAAGTCTGATGGGGAGAATGAAGAGCAAGATCATCTTGCTTCT
TATCTAATCGGTAGCTGAAGACTCCAGTCTGAGAAGAGCCTCAGGGAGAAAGTAGCTAATACAC
ACCGCACAGCAACCTCAGTGTATGGGGACAGCTTAGTTGAAAAGTGCCCTGCGACAGCGACAGC
TGGCTCTGTGGAGGGTGCAGATGGAGTTTTCTCTTCTTCCCACCAGGTGGCACTAGAGGAAAGG
GTTTTGATCAACCTAATTTTGTATCTACCATTGGTTCTTCAAAAGTCCTTATCTAAGTGGAAAG
GTGTCTTACATGTAGTTTGATTCTAAGTCACCATGCTTATGAATGCTGTGAATCCCAGCATTAA
AGAGAATTAATGCTAAGTGTGTCAGTAAAGGCAGACAAATGACACTAACATAACACTAAACGAC
CTTAGAAGTTCATTTAAATTGTACATAGAGTTCAGTATTGCACCGTTTACAGGGTGTCCAGCAT
GACCACTTTTTCTGCCAGTATTAGAAACAGGGCATGAATTTGAACACCAGAAGAAGTGCACTAT
AAATCCTTGAATTAATAGCCGAAAAGACACTTTCCCGAAATAATGTTTTAAATGTAAGAAAACA
ATAAGCTGTAAGTAGAATTCCCTGTAACAGTGCACTTGCAGAGAGCTACGCAGTAAGTCTGAAT
TTATTTAAGTCTTTCACATTTTCACCCGGTGTCTGGAAGGCAGCTCTGTTGTTCTGGTGCTTTA
AAAAGATACGCGATTATCATCAAGCTGTCTGTATGCTTTATTTTTGTCTGTTATGTGTCAGGAC
ACTATCTGCTATAACCACTGTATTCTGTTAAATAAACACAGCACATTTTGTTTATTTGTTTTCG
CA

hide sequence

RefSeq Acc Id:

XM_005378728 ⟹ XP_005378785

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955413	2,129,719 - 2,153,873 (+)	NCBI

Sequence:

show sequence

GTGGCGGAAGTGGAGCGGGGAGGTAGCAACGGTGCAGAACGCCGGGCTGTGTGCTGTGTTCCCA
GTCCAGCGGCGCCCAGCCTCCCACGGCTGCTCGGACATGACGCGCTTCGCCCTCACCGTGGTCC
GGCATGGAGAAACGAGACTTAACAAGGAGAAAATACTTCAAGGACAAGGCGTGGACGAGCCCCT
TTCCGAGACTGGGTTCAAACAGGCGGCTGCGGCGGGGAGTTTTCTGAAAAATGTGCTGTTCACA
CACGCGTTTTCCAGCGACCTCACCAGGACGAGGCAGACCACCCATGAGATTTTGGAGAAAAGCA
AATTTTGCAAAGACATGACAGTAAAGTATGATTCAAGACTTCGCGAAAGGAGGTACGGGGCTGC
TGAAGGCAAGGCGCTGAGCGAGCTGCGGGCCATGGCCAAGGCTGCGGGGATGGAGTGCCCGGTG
TTCACGCCTCCCGGAGGAGAGACGCTGGAGCAGGTAAAAACGCGTGGAAAAGATTTCTTTGAAT
TTCTTTGTCAACTAATCCTAAAAGAAGCAGGTCAGAATGAACAGCTTTCCCCAGAAGTCCCAGT
CAACTATCTGGAAACTTCTTTGGCGGAGATATTTCCTTTAGGAGAAAACTGCAGTCCCGAGTGC
TGTGTGGACCGCGGCCATCCAGGACTGGCAGCCAGCATCTTGGTGGTGAGCCACGGGGCCTACA
TGAGGAGCCTTTTCAGCTATTTTCTGACCGACCTGAAGGGCTCCTTGCCAGCACTTCTGAACAG
ATCGGAACTTCTGTCTGTCAGCCCCAACACTGGGATCAGCCTCTTCATCATAGACCTCGAAGAG
GGTCGGGAACCCGAGGTCCACTGCGTCTGCATGAACCTGCAGGATCACCTGAACGGAGTCAACT
GAAGGCGCCGAGTTCCAGCGGTGTTAGAATCTGAGCAATTTGAGGGTCTGTAGGGAGCACCTTT
GGCTTGCTTCAGTTCTGTCCTTTGCTGTGGTGATTTGGAAACAATGAAAAATCAGCTTGTAAAC
CTCTATCCCAAACAATGATGGAAAGCCATTTTGCACTGATTTAATTTTTACAAGCGCTGTTTGC
ATTTTCCAGAGTAATTTTGCTGCCCTACTCAGTCACATCTCCATATTGAAAATGGGCAGAGGAA
CTGAGCATTGCAGTTGGGTATTAATCACCTTTTACTGTGTCTTCCCTGTTTTAAAATGTTGATG
TATTTTTTTAATGCTCAGCTTATATTATTGGCTCCTGCTAAAATACTGTATGCTTTTTGCATCT
CATCTGGTGCTTCAGTGAAGGAGCTCCCTGTAAATGACACTGCATATTTGTAGCAACTGTGTTA
TATTTAAAAAGGAAATATTCTTTAAAGGAAATAGTGTCCCCATTATAAGTTCATGTAAAGTAAA
ATGATAAGAGAACACTAAATGTTGTATGTAGAAACCAGCCGTTGGAATATTTATTTTTATTCTA
GAGGGCCCAGGTGTGGATGAGGATACACTGTGACTGCAGAAAGGCGCAGAGAGAGGTTGGGCAC
CATGCGGTTAGAATACCTTACTGAAAGTAATGGAGCTTGTTCAGGATACCTTGCAAAAGCTGCC
AGTGAGAACCGGGAAAATAAACAAAAACACACAAAAAACCCAAAGTCTGATGGGGAGAATGAAG
AGCAAGATCATCTTGCTTCTTATCTAATCGGTAGCTGAAGACTCCAGTCTGAGAAGAGCCTCAG
GGAGAAAGTAGCTAATACACACCGCACAGCAACCTCAGTGTATGGGGACAGCTTAGTTGAAAAG
TGCCCTGCGACAGCGACAGCTGGCTCTGTGGAGGGTGCAGATGGAGTTTTCTCTTCTTCCCACC
AGGTGGCACTAGAGGAAAGGGTTTTGATCAACCTAATTTTGTATCTACCATTGGTTCTTCAAAA
GTCCTTATCTAAGTGGAAAGGTGTCTTACATGTAGTTTGATTCTAAGTCACCATGCTTATGAAT
GCTGTGAATCCCAGCATTAAAGAGAATTAATGCTAAGTGTGTCAGTAAAGGCAGACAAATGACA
CTAACATAACACTAAACGACCTTAGAAGTTCATTTAAATTGTACATAGAGTTCAGTATTGCACC
GTTTACAGGGTGTCCAGCATGACCACTTTTTCTGCCAGTATTAGAAACAGGGCATGAATTTGAA
CACCAGAAGAAGTGCACTATAAATCCTTGAATTAATAGCCGAAAAGACACTTTCCCGAAATAAT
GTTTTAAATGTAAGAAAACAATAAGCTGTAAGTAGAATTCCCTGTAACAGTGCACTTGCAGAGA
GCTACGCAGTAAGTCTGAATTTATTTAAGTCTTTCACATTTTCACCCGGTGTCTGGAAGGCAGC
TCTGTTGTTCTGGTGCTTTAAAAAGATACGCGATTATCATCAAGCTGTCTGTATGCTTTATTTT
TGTCTGTTATGTGTCAGGACACTATCTGCTATAACCACTGTATTCTGTTAAATAAACACAGCAC
ATTTTGTTTATTTGTTTTCGCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005378784	(Get FASTA)	NCBI Sequence Viewer
	XP_005378785	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000019122
	ENSCLAP00000019122.1

RefSeq Acc Id:	XP_005378785 ⟸ XM_005378728
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2YS21 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTRFALTVVRHGETRLNKEKILQGQGVDEPLSETGFKQAAAAGSFLKNVLFTHAFSSDLTRTRQ TTHEILEKSKFCKDMTVKYDSRLRERRYGAAEGKALSELRAMAKAAGMECPVFTPPGGETLEQV KTRGKDFFEFLCQLILKEAGQNEQLSPEVPVNYLETSLAEIFPLGENCSPECCVDRGHPGLAAS ILVVSHGAYMRSLFSYFLTDLKGSLPALLNRSELLSVSPNTGISLFIIDLEEGREPEVHCVCMN LQDHLNGVN hide sequence

RefSeq Acc Id:

XP_005378784 ⟸ XM_005378727

- Peptide Label:

isoform X1

- Sequence:

show sequence

MLQLSLSPRPPACCLLSGETRLNKEKILQGQGVDEPLSETGFKQAAAAGSFLKNVLFTHAFSSD
LTRTRQTTHEILEKSKFCKDMTVKYDSRLRERRYGAAEGKALSELRAMAKAAGMECPVFTPPGG
ETLEQVKTRGKDFFEFLCQLILKEAGQNEQLSPEVPVNYLETSLAEIFPLGENCSPECCVDRGH
PGLAASILVVSHGAYMRSLFSYFLTDLKGSLPALLNRSELLSVSPNTGISLFIIDLEEGREPEV
HCVCMNLQDHLNGVN

hide sequence

Ensembl Acc Id:

ENSCLAP00000019122 ⟸ ENSCLAT00000019307

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000013103	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000019307	ENTREZGENE
	ENSCLAT00000019307.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1240	UniProtKB/TrEMBL
InterPro	His_Pase_superF_clade-1	UniProtKB/TrEMBL
	His_PPase_superfam	UniProtKB/TrEMBL
	PG/BPGM_mutase_AS	UniProtKB/TrEMBL
	Phosphoglycerate_Mutase	UniProtKB/TrEMBL
NCBI Gene	LOC102029277	ENTREZGENE
PANTHER	FRUCTOSE-2,6-BISPHOSPHATASE TIGAR	UniProtKB/TrEMBL
	FRUCTOSE-2,6-BISPHOSPHATASE TIGAR	UniProtKB/TrEMBL
Pfam	His_Phos_1	UniProtKB/TrEMBL
PIRSF	6PFK_2-Ptase	UniProtKB/TrEMBL
PROSITE	PG_MUTASE	UniProtKB/TrEMBL
SMART	PGAM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53254	UniProtKB/TrEMBL
UniProt	A0A8C2YS21	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Tigar	TP53 induced glycolysis regulatory phosphatase	LOC102029277	chromosome unknown open reading frame, human C12orf5	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD