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Gene: Alkbh3 (alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase) Rattus norvegicus

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Symbol:

Alkbh3

Name:

alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase

RGD ID:

1359731

Description:

Predicted to enable DNA demethylase activity; ferrous iron binding activity; and mRNA N1-methyladenosine dioxygenase activity. Predicted to be involved in DNA alkylation repair; cell population proliferation; and negative regulation of cytoplasmic translation. Predicted to be located in cytosol. Predicted to be active in mitochondrion and nucleoplasm. Orthologous to human ALKBH3 (alkB homolog 3, alpha-ketoglutarate dependent dioxygenase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

AlkB homolog 3; alkB, alkylation repair homolog 3; alkB, alkylation repair homolog 3 (E. coli); alkylated DNA repair protein alkB homolog 3; alkylation repair-like protein 3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; LOC362169; similar to RIKEN cDNA 1810020C19 gene

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	100,394,942 - 100,429,466 (-)	NCBI		GRCr8
mRatBN7.2	3	79,939,515 - 79,972,820 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	79,939,600 - 79,972,000 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	83,413,118 - 83,445,373 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	92,012,208 - 92,044,463 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	89,857,713 - 89,889,968 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	82,874,242 - 82,907,467 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	82,874,248 - 82,906,581 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	89,575,451 - 89,608,158 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	78,386,098 - 78,418,432 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	78,282,525 - 78,314,860 (-)	NCBI
Celera	3	79,141,033 - 79,172,722 (-)	NCBI		Celera
Cytogenetic Map	3	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Alkbh3	Rat	intellectual disability		ISO	ALKBH3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Intellectual disability	ClinVar

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Alkbh3	Rat	(1->4)-beta-D-glucan	multiple interactions	ISO	Alkbh3 (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ALKBH3 mRNA	CTD	PMID:36331819
Alkbh3	Rat	1,2-dimethylhydrazine	increases expression	ISO	Alkbh3 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in increased expression of ALKBH3 mRNA	CTD	PMID:22206623
Alkbh3	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Alkbh3 (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of ALKBH3 mRNA	CTD	PMID:21570461
Alkbh3	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of ALKBH3 mRNA	CTD	PMID:33387578
Alkbh3	Rat	2,4-dinitrotoluene	affects expression	EXP		6480464	2 and 4-dinitrotoluene affects the expression of ALKBH3 mRNA	CTD	PMID:21346803
Alkbh3	Rat	2,6-dinitrotoluene	affects expression	EXP		6480464	2 and 6-dinitrotoluene affects the expression of ALKBH3 mRNA	CTD	PMID:21346803
Alkbh3	Rat	2-hydroxyglutaric acid	decreases activity	ISO	ALKBH3 (Homo sapiens)	6480464	alpha-hydroxyglutarate results in decreased activity of ALKBH3 protein	CTD	PMID:28269980
Alkbh3	Rat	2-hydroxypropanoic acid	decreases expression	ISO	ALKBH3 (Homo sapiens)	6480464	Lactic Acid results in decreased expression of ALKBH3 mRNA	CTD	PMID:30851411
Alkbh3	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	Alkbh3 (Mus musculus)	6480464	bisphenol S results in increased expression of ALKBH3 mRNA	CTD	PMID:39298647
Alkbh3	Rat	aconitine	increases expression	EXP		6480464	Aconitine results in increased expression of ALKBH3 protein	CTD	PMID:33236894
Alkbh3	Rat	acrylamide	increases expression	ISO	ALKBH3 (Homo sapiens)	6480464	Acrylamide results in increased expression of ALKBH3 mRNA	CTD	PMID:32763439
Alkbh3	Rat	aflatoxin B1	increases methylation	ISO	ALKBH3 (Homo sapiens)	6480464	Aflatoxin B1 results in increased methylation of ALKBH3 gene	CTD	PMID:27153756
Alkbh3	Rat	Aflatoxin B2 alpha	increases methylation	ISO	ALKBH3 (Homo sapiens)	6480464	aflatoxin B2 results in increased methylation of ALKBH3 intron	CTD	PMID:30157460
Alkbh3	Rat	atrazine	decreases expression	ISO	ALKBH3 (Homo sapiens)	6480464	Atrazine results in decreased expression of ALKBH3 mRNA	CTD	PMID:22378314
Alkbh3	Rat	benzo[a]pyrene	multiple interactions	ISO	Alkbh3 (Mus musculus)	6480464	Benzo(a)pyrene promotes the reaction [AHR protein binds to ALKBH3 promoter]	CTD	PMID:19654925
Alkbh3	Rat	benzo[a]pyrene	affects methylation	ISO	ALKBH3 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of ALKBH3 5' UTR and Benzo(a)pyrene affects the methylation of ALKBH3 intron	CTD	PMID:27901495 and PMID:30157460
Alkbh3	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of ALKBH3 mRNA	CTD	PMID:25181051
Alkbh3	Rat	bisphenol A	multiple interactions	ISO	ALKBH3 (Homo sapiens)	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of ALKBH3 gene	CTD	PMID:31601247
Alkbh3	Rat	bisphenol A	increases methylation	EXP		6480464	bisphenol A results in increased methylation of ALKBH3 gene	CTD	PMID:28505145
Alkbh3	Rat	bisphenol F	decreases expression	ISO	Alkbh3 (Mus musculus)	6480464	bisphenol F results in decreased expression of ALKBH3 mRNA	CTD	PMID:38685157
Alkbh3	Rat	CGP 52608	multiple interactions	ISO	ALKBH3 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to ALKBH3 gene]	CTD	PMID:28238834
Alkbh3	Rat	chlordecone	decreases expression	ISO	Alkbh3 (Mus musculus)	6480464	Chlordecone results in decreased expression of ALKBH3 mRNA	CTD	PMID:29980752
Alkbh3	Rat	copper(II) chloride	decreases activity	ISO	ALKBH3 (Homo sapiens)	6480464	cupric chloride results in decreased activity of ALKBH3 protein	CTD	PMID:28926697
Alkbh3	Rat	cyclosporin A	increases expression	ISO	ALKBH3 (Homo sapiens)	6480464	Cyclosporine results in increased expression of ALKBH3 mRNA	CTD	PMID:20106945 and PMID:27989131
Alkbh3	Rat	Dibutyl phosphate	affects expression	ISO	ALKBH3 (Homo sapiens)	6480464	di-n-butylphosphoric acid affects the expression of ALKBH3 mRNA	CTD	PMID:37042841
Alkbh3	Rat	dibutyl phthalate	decreases expression	EXP		6480464	Dibutyl Phthalate results in decreased expression of ALKBH3 mRNA	CTD	PMID:21266533
Alkbh3	Rat	dibutyl phthalate	increases expression	EXP		6480464	Dibutyl Phthalate results in increased expression of ALKBH3 mRNA	CTD	PMID:21266533
Alkbh3	Rat	epoxiconazole	decreases expression	ISO	Alkbh3 (Mus musculus)	6480464	epoxiconazole results in decreased expression of ALKBH3 mRNA	CTD	PMID:35436446
Alkbh3	Rat	flutamide	increases expression	EXP		6480464	Flutamide results in increased expression of ALKBH3 mRNA	CTD	PMID:24136188
Alkbh3	Rat	fonofos	increases methylation	ISO	ALKBH3 (Homo sapiens)	6480464	Fonofos results in increased methylation of ALKBH3 promoter	CTD	PMID:22847954
Alkbh3	Rat	fulvestrant	multiple interactions	ISO	ALKBH3 (Homo sapiens)	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of ALKBH3 gene	CTD	PMID:31601247
Alkbh3	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of ALKBH3 mRNA	CTD	PMID:33387578
Alkbh3	Rat	methyl methanesulfonate	increases expression	ISO	ALKBH3 (Homo sapiens)	6480464	Methyl Methanesulfonate results in increased expression of ALKBH3 mRNA	CTD	PMID:23649840
Alkbh3	Rat	parathion	increases methylation	ISO	ALKBH3 (Homo sapiens)	6480464	Parathion results in increased methylation of ALKBH3 promoter	CTD	PMID:22847954
Alkbh3	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	Alkbh3 (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ALKBH3 mRNA	CTD	PMID:36331819
Alkbh3	Rat	pirinixic acid	increases expression	ISO	Alkbh3 (Mus musculus)	6480464	pirinixic acid results in increased expression of ALKBH3 mRNA	CTD	PMID:18301758
Alkbh3	Rat	rac-lactic acid	decreases expression	ISO	ALKBH3 (Homo sapiens)	6480464	Lactic Acid results in decreased expression of ALKBH3 mRNA	CTD	PMID:30851411
Alkbh3	Rat	resveratrol	multiple interactions	ISO	ALKBH3 (Homo sapiens)	6480464	[Plant Extracts co-treated with Resveratrol] results in increased expression of ALKBH3 mRNA	CTD	PMID:23557933
Alkbh3	Rat	streptozocin	multiple interactions	EXP		6480464	[Streptozocin co-treated with Dietary Fats] results in decreased expression of ALKBH3 mRNA	CTD	PMID:20665664
Alkbh3	Rat	sunitinib	increases expression	ISO	ALKBH3 (Homo sapiens)	6480464	Sunitinib results in increased expression of ALKBH3 mRNA	CTD	PMID:31533062
Alkbh3	Rat	terbufos	increases methylation	ISO	ALKBH3 (Homo sapiens)	6480464	terbufos results in increased methylation of ALKBH3 promoter	CTD	PMID:22847954
Alkbh3	Rat	titanium dioxide	affects methylation	ISO	Alkbh3 (Mus musculus)	6480464	titanium dioxide affects the methylation of ALKBH3 enhancer	CTD	PMID:35295148
Alkbh3	Rat	titanium dioxide	decreases methylation	ISO	Alkbh3 (Mus musculus)	6480464	titanium dioxide results in decreased methylation of ALKBH3 promoter	CTD	PMID:35295148
Alkbh3	Rat	triphenyl phosphate	affects expression	ISO	ALKBH3 (Homo sapiens)	6480464	triphenyl phosphate affects the expression of ALKBH3 mRNA	CTD	PMID:37042841
Alkbh3	Rat	tunicamycin	increases expression	ISO	ALKBH3 (Homo sapiens)	6480464	Tunicamycin results in increased expression of ALKBH3 mRNA	CTD	PMID:29453283
Alkbh3	Rat	valproic acid	increases methylation	ISO	ALKBH3 (Homo sapiens)	6480464	Valproic Acid results in increased methylation of ALKBH3 gene	CTD	PMID:29154799
Alkbh3	Rat	valproic acid	increases expression	ISO	ALKBH3 (Homo sapiens)	6480464	Valproic Acid results in increased expression of ALKBH3 mRNA	CTD	PMID:29154799

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Alkbh3	Rat	cell population proliferation	involved_in	ISS	UniProtKB:Q96Q83	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Alkbh3	Rat	cell population proliferation	involved_in	IEA	UniProtKB:Q96Q83 and ensembl:ENSP00000302232	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Alkbh3	Rat	cell population proliferation	involved_in	ISO	ALKBH3 (Homo sapiens)	1624291	PMID:22055184	RGD	PMID:22055184
Alkbh3	Rat	DNA alkylation repair	involved_in	ISO	ALKBH3 (Homo sapiens)	1624291	PMID:20714506 and PMID:22055184	RGD	PMID:20714506 and PMID:22055184
Alkbh3	Rat	DNA alkylation repair	involved_in	IEA	UniProtKB:Q96Q83 and ensembl:ENSP00000302232	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Alkbh3	Rat	DNA alkylation repair	involved_in	IEA	InterPro:IPR032854	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Alkbh3	Rat	DNA damage response	involved_in	IEA	UniProtKB-KW:KW-0227	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Alkbh3	Rat	DNA repair	involved_in	IBA	PANTHER:PTN001261013 and UniProtKB:Q96Q83	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Alkbh3	Rat	DNA repair	involved_in	IEA	InterPro:IPR032854	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Alkbh3	Rat	DNA repair	involved_in	IEA	UniProtKB-KW:KW-0234	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Alkbh3	Rat	negative regulation of cytoplasmic translation	involved_in	ISO	ALKBH3 (Homo sapiens)	1624291	PMID:26863196	RGD	PMID:26863196
Alkbh3	Rat	negative regulation of cytoplasmic translation	involved_in	IEA	UniProtKB:Q96Q83 and ensembl:ENSP00000302232	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Alkbh3	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Alkbh3	Rat	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Alkbh3	Rat	cytosol	located_in	ISO	ALKBH3 (Homo sapiens) and UniProtKB:Q96Q83-1	1624291		RGD	GO_REF:0000052
Alkbh3	Rat	cytosol	located_in	IEA	UniProtKB:Q96Q83 and ensembl:ENSP00000302232	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Alkbh3	Rat	mitochondrion	located_in	ISO	ALKBH3 (Homo sapiens) and UniProtKB:Q96Q83-1	1624291		RGD	GO_REF:0000052
Alkbh3	Rat	mitochondrion	located_in	IEA	UniProtKB:Q96Q83 and ensembl:ENSP00000302232	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Alkbh3	Rat	mitochondrion	is_active_in	IBA	PANTHER:PTN001261013 and UniProtKB:Q96Q83	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Alkbh3	Rat	nucleoplasm	is_active_in	IBA	PANTHER:PTN001261013 and UniProtKB:Q96Q83	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Alkbh3	Rat	nucleoplasm	located_in	IEA	UniProtKB:Q96Q83 and ensembl:ENSP00000302232	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Alkbh3	Rat	nucleoplasm	located_in	ISO	ALKBH3 (Homo sapiens) and UniProtKB:Q96Q83-1	1624291		RGD	GO_REF:0000052
Alkbh3	Rat	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Alkbh3	Rat	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Alkbh3	Rat	2-oxoglutarate-dependent dioxygenase activity	enables	ISO	Alkbh3 (Mus musculus)	1624291	PMID:16174769	RGD	PMID:16174769
Alkbh3	Rat	broad specificity oxidative DNA demethylase activity	enables	ISO	ALKBH3 (Homo sapiens)	1624291	PMID:12486230 more ...	RGD	PMID:12486230 more ...
Alkbh3	Rat	broad specificity oxidative DNA demethylase activity	enables	IEA	RHEA:30299	1600115	GO_REF:0000116	RHEA	GO_REF:0000116
Alkbh3	Rat	broad specificity oxidative DNA demethylase activity	enables	IEA	UniProtKB:Q96Q83 and ensembl:ENSP00000302232	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Alkbh3	Rat	broad specificity oxidative DNA demethylase activity	enables	ISS	UniProtKB:Q96Q83	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Alkbh3	Rat	broad specificity oxidative DNA demethylase activity	enables	ISO	Alkbh3 (Mus musculus)	1624291	PMID:16174769	RGD	PMID:16174769
Alkbh3	Rat	cytosine C-5 DNA demethylase activity	enables	ISO	Alkbh3 (Mus musculus)	1624291	PMID:16174769	RGD	PMID:16174769
Alkbh3	Rat	dioxygenase activity	enables	IEA	InterPro:IPR032854	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Alkbh3	Rat	dioxygenase activity	enables	IEA	UniProtKB-KW:KW-0223	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Alkbh3	Rat	endonuclease activity	NOT\|enables	ISO	Alkbh3 (Mus musculus)	1624291	PMID:16174769	RGD	PMID:16174769
Alkbh3	Rat	exonuclease activity	NOT\|enables	ISO	Alkbh3 (Mus musculus)	1624291	PMID:16174769	RGD	PMID:16174769
Alkbh3	Rat	ferrous iron binding	enables	ISS	UniProtKB:Q96Q83	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Alkbh3	Rat	ferrous iron binding	enables	IEA	UniProtKB:Q96Q83 and ensembl:ENSP00000302232	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Alkbh3	Rat	ferrous iron binding	enables	ISO	ALKBH3 (Homo sapiens)	1624291	PMID:16858410	RGD	PMID:16858410
Alkbh3	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Alkbh3	Rat	mRNA N1-methyladenosine dioxygenase activity	enables	ISS	UniProtKB:Q96Q83	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Alkbh3	Rat	mRNA N1-methyladenosine dioxygenase activity	enables	IEA	RHEA:49516	1600115	GO_REF:0000116	RHEA	GO_REF:0000116
Alkbh3	Rat	mRNA N1-methyladenosine dioxygenase activity	enables	IEA	UniProtKB:Q96Q83 and ensembl:ENSP00000302232	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Alkbh3	Rat	mRNA N1-methyladenosine dioxygenase activity	enables	IEA	EC:1.14.11.54	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Alkbh3	Rat	mRNA N1-methyladenosine dioxygenase activity	enables	ISO	ALKBH3 (Homo sapiens)	1624291	PMID:26863196 and PMID:26863410	RGD	PMID:26863196 and PMID:26863410
Alkbh3	Rat	oxidative RNA demethylase activity	enables	ISO	ALKBH3 (Homo sapiens)	1624291	PMID:16174769	RGD	PMID:16174769
Alkbh3	Rat	oxidative RNA demethylase activity	enables	IEA	UniProtKB:Q96Q83 and ensembl:ENSP00000302232	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Alkbh3	Rat	oxidative RNA demethylase activity	enables	ISO	Alkbh3 (Mus musculus)	1624291	PMID:16174769	RGD	PMID:16174769
Alkbh3	Rat	oxidoreductase activity	enables	IEA	UniProtKB-KW:KW-0560	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Alkbh3	Rat	protein binding	enables	ISO	ALKBH3 (Homo sapiens) and UniProtKB:Q96Q83-2	1624291	UniProtKB:O75400-2 more ...	RGD	PMID:32814053
Alkbh3	Rat	protein binding	enables	ISO	ALKBH3 (Homo sapiens)	1624291	UniProtKB:O76003 more ...	RGD	PMID:22055184 more ...

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

PMID:15489334	PMID:16174769	PMID:16858410	PMID:22055184	PMID:26863196	PMID:26863410

Alkbh3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	100,394,942 - 100,429,466 (-)	NCBI		GRCr8
mRatBN7.2	3	79,939,515 - 79,972,820 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	79,939,600 - 79,972,000 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	83,413,118 - 83,445,373 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	92,012,208 - 92,044,463 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	89,857,713 - 89,889,968 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	82,874,242 - 82,907,467 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	82,874,248 - 82,906,581 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	89,575,451 - 89,608,158 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	78,386,098 - 78,418,432 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	78,282,525 - 78,314,860 (-)	NCBI
Celera	3	79,141,033 - 79,172,722 (-)	NCBI		Celera
Cytogenetic Map	3	q31	NCBI

ALKBH3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	43,880,831 - 43,920,274 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	43,880,811 - 43,920,274 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	43,902,381 - 43,941,824 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	43,858,971 - 43,898,389 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	44,048,227 - 44,087,676 (+)	NCBI		Celera
Cytogenetic Map	11	p11.2	NCBI
HuRef	11	43,611,668 - 43,651,108 (+)	NCBI		HuRef
CHM1_1	11	43,901,678 - 43,940,820 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	44,036,210 - 44,075,625 (+)	NCBI		T2T-CHM13v2.0

Alkbh3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	93,810,979 - 93,841,099 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	93,810,895 - 93,841,152 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	93,980,624 - 94,010,824 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	93,980,550 - 94,010,807 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	93,820,791 - 93,850,887 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	93,781,391 - 93,811,646 (-)	NCBI		MGSCv36	mm8
Celera	2	95,377,139 - 95,407,273 (-)	NCBI		Celera
Cytogenetic Map	2	E1	NCBI
cM Map	2	51.62	NCBI

Alkbh3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	3,657,765 - 3,695,409 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	3,660,504 - 3,695,352 (-)	NCBI	ChiLan1.0	ChiLan1.0

ALKBH3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	46,095,666 - 46,135,186 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	46,101,637 - 46,141,224 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	43,841,083 - 43,880,608 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	44,336,655 - 44,376,058 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	44,336,655 - 44,376,057 (+)	Ensembl	panpan1.1		panPan2

ALKBH3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	25,864,041 - 25,899,226 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	25,824,877 - 25,899,079 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	25,551,100 - 25,585,936 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	26,486,584 - 26,521,476 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	26,449,542 - 26,519,594 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	25,996,121 - 26,030,947 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	25,641,660 - 25,676,520 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	26,253,706 - 26,288,540 (-)	NCBI		UU_Cfam_GSD_1.0

Alkbh3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	22,615,131 - 22,666,079 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936562	4,741,371 - 4,777,727 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936562	4,743,595 - 4,777,685 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ALKBH3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	18,408,987 - 18,446,056 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	18,408,987 - 18,448,285 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	20,011,987 - 20,048,360 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ALKBH3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	21,463,744 - 21,505,940 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	21,462,516 - 21,505,934 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	118,701,961 - 118,743,776 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Alkbh3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	4,103,446 - 4,139,345 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	4,088,173 - 4,139,288 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Alkbh3
166 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	116
Count of miRNA genes:	94
Interacting mature miRNAs:	96
Transcripts:	ENSRNOT00000030784
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	43827364	90905114	Rat
61377	Edpm3	Estrogen-dependent pituitary mass QTL 3	7.05	0.038	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	53184692	89878207	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	39454637	89115240	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	39454637	89115240	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	53781112	91609953	Rat
738019	Anxrr10	Anxiety related response QTL 10	3.9		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	3	38517803	83517803	Rat
631200	Cm25	Cardiac mass QTL 25	4.8	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	3	61134348	89115068	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	30356773	98535386	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	41874578	104104347	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	104104347	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001014180	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105433	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC140988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083756	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KF027342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000030784 ⟹ ENSRNOP00000030278

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	79,939,600 - 79,972,000 (-)	Ensembl
Rnor_6.0 Ensembl	3	82,874,248 - 82,906,581 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112362 ⟹ ENSRNOP00000093084

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	79,939,600 - 79,972,000 (-)	Ensembl

RefSeq Acc Id:

NM_001014180 ⟹ NP_001014202

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	100,394,947 - 100,427,281 (-)	NCBI
mRatBN7.2	3	79,939,599 - 79,971,934 (-)	NCBI
Rnor_6.0	3	82,874,247 - 82,906,581 (-)	NCBI
Rnor_5.0	3	89,575,451 - 89,608,158 (-)	NCBI
RGSC_v3.4	3	78,386,098 - 78,418,432 (-)	RGD
Celera	3	79,141,033 - 79,172,722 (-)	RGD

Sequence:

show sequence

CCGGCGTCCGGACAGCTGAGCGGCTAACGAAAGTCGGAAACTTTTCTCAGGCCCAGCCAGGTAACCATTCCATGGTCTGAATGGGGAACGAAATCTCCTGAAATCTCAGAACAGAACGCTCTTTCTTC
AACATGGGGGACAAGAGACAGCGAGCCCGAGTGCAGGGAGCCTGGGCCACACCTACCAAGAGCCAGTCTGCTGCTCGGCCAGCTACTCCTGCTAGAAGCCGTCCTTCCCAGACACCAGGGCCAAGCTG
GAGGAGCAAGGAACAGCAGCAATGTGACCGACGGTTTGTGTTCAAAGAACCGCAGCTGGTTGTACGTGCAGCCCCAGAGCCCAGAGTGATTGACAGGGAGGGTGTGTACGAAATCAGCCTGTCCCCTA
CAGGTGTGTCTAGGGTGTGTTTATATCCTGGCTTTGTGGACTTGAAGGAAGCTGACTGGATCTTGGAGCGGCTTTGTCAAGATGTCCCCTGGAAACAGAGGATGGGCATCAGAGAGGATATAACTTAT
CCGCAACCAAGACTTACAGCATGGTATGGAGAGCTTCCTTACACTTACTCAAGAGTCACTATGGAACCAAATCCTCACTGGCTTCCTGTGCTGTGGACTCTGAAGAGCCGCATTGAGGAGAACACTGG
CCACACCTTCAACTCCTTGCTGTGTAATTTTTACCGGGACGAGAAGGACAGTGTGGACTGGCACAGCGATGATGAGCCATCCCTGGGGAGCTGCCCTGTCATTGCTTCACTCAGTTTTGGTGCCACTC
GGACTTTTGAGATGAGGAAGAAACCCCCACCTGAAGAGAATGGAGACTATACTTATGTGGAGAGAGTGAAGATACCATTGGATCACGGGACCTTGCTAATCATGGAAGGAGCCACGCAAGCTGACTGG
CAGCACCGAGTGCCCAAGGAATACCACTCCAGAGAACGGAGAGTAAACCTAACCTTTCGGACCGTTTATCCAGACCCAAGAGGAGCCCCCGGTGATACTTCTGCAGAGCTGCCACTGAGGTGAGGGCT
GTGCACCCAGCAGCCCCTCCCCATCTCCCAGAAGCACTTCCAGAAGCTGCTGCGTGTACCTCCGTGATGTGGCTGTTTGGAAATTGTGTTTGCTTCTCAGGTCCTATTCCTCCTGAATGAGAGCTACC
AACACTTCATGCTGTCCGCATGTCTACTATAGGGACAGTTACTTGAGACAACTCTCTAAATCAAGGGTTGTCCTTAGGCAAATTAAAAACTGCTCTGGCTGTGCTTACAAAAAAAAAAAAAAAAAAAA
AAAAAA

hide sequence

RefSeq Acc Id:

XM_006234585 ⟹ XP_006234647

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	100,394,942 - 100,427,368 (-)	NCBI
mRatBN7.2	3	79,939,518 - 79,972,026 (-)	NCBI
Rnor_6.0	3	82,874,242 - 82,907,467 (-)	NCBI
Rnor_5.0	3	89,575,451 - 89,608,158 (-)	NCBI

Sequence:

show sequence

ACATTTATTGGTACCCTGACAGTGTCAGGCTTATTTGAGAGATTTCCACAATGATCATATTTTG
GTAAATTTTAGAGAACAATTTGCAGAAAATAGTTGACTCAGTGCTACAGTTAGAATTGTCAAATTATGAGACATGGCTTAACCGGGCTTCTTTAAAGATGCTTGTCAGGAGGTCAGGTGGGTGAAAAG
GCACTTTGCGCTATCTTGAATTATTAGATTTATATAGTGTTCCAGACACTGTTATCTCATTTAATCCCACTAAGAGGAGCTATGGCCTCTTAAAAAGTAAGCGGAGCACTTGCCCCAAATGGTGGCAT
TGCAATGAAATTTAGACAGATCTGTGGACTCAAGTAAAGTTTACTTAGCACTGAGGAACTCAGTCAAATAAGGCCTGCTTTCATGTTCCACCGTAAATGATGTGTAGAAAAGATGGGCACGCTACGTT
GAGAACAAAGTGCACCTTAGACTCTTCATGGTTTTCGAGGTAACAAGAGAATTCTATAGCTGAACACATGACCCAAGTCCTCCCCACTCCGGAATCAGTAGAAGTTCCGGGAGACTGCGGTTGCCCTT
TGCACAAGAGAACAAAGATGCCAGCACTAGTTTCGGGAATTTATGCCCTGAGGACCTAGGCCTAAGAGGCTCATCTTCATTCCCACCTCCGCCTCACCAGGGCCACCATCAGCCCCCAATTCCTGTCC
CCAGTTCCGACCTTATTCCCTTCAGCATCTCCATCCGGCCCTTTAGGCGCCAGGGATGCGGGGCGACCCGGACTCCCGGCTACCCACAGGAAGCGGTGGCAGGGTGTAACAGAAGAGGAAGTACGTGT
AACGGAGGCCAGTGGTTGGGCGTTGCAGGAGTTGGTGTCTCACTCTGAAGTTCCCCGGCGTCCGGACAGCTGAGCGGCTAACGAAAGTCGGAAACTTTTCTCAGGCCCAGCCAGCAGGTAACCATTCC
ATGGTCTGAATGGGGAACGAAATCTCCTGAAATCTCAGAACAGAACGCTCTTTCTTCAACATGGGGGACAAGAGACAGCGAGCCCGAGTGCAGGGAGCCTGGGCCACACCTACCAAGAGCCAGTCTGC
TGCTCGGCCAGCTACTCCTGCTAGAAGCCGTCCTTCCCAGACACCAGGGCCAAGCTGGAGGAGCAAGGAACAGCAGCAATGTGACCGACGGTTTGTGTTCAAAGAACCGCAGCTGGTTGTACGTGCAG
CCCCAGAGCCCAGAGTGATTGACAGGGAGGGTGTGTACGAAATCAGCCTGTCCCCTACAGGTGTGTCTAGGGTGTGTTTATATCCTGGCTTTGTGGACTTGAAGGAAGCTGACTGGATCTTGGAGCGG
CTTTGTCAAGATGTCCCCTGGAAACAGAGGATGGGCATCAGAGAGGATATAACTTATCCGCAACCAAGACTTACAGCATGGTATGGAGAGCTTCCTTACACTTACTCAAGAGTCACTATGGAACCAAA
TCCTCACTGGCTTCCTGTGCTGTGGACTCTGAAGAGCCGCATTGAGGAGAACACTGGCCACACCTTCAACTCCTTGCTGTGTAATTTTTACCGGGACGAGAAGGACAGTGTGGACTGGCACAGCGATG
ATGAGCCATCCCTGGGGAGCTGCCCTGTCATTGCTTCACTCAGTTTTGGTGCCACTCGGACTTTTGAGATGAGGAAGAAACCCCCACCTGAAGAGAATGGAGACTATACTTATGTGGAGAGAGTGAAG
ATACCATTGGATCACGGGACCTTGCTAATCATGGAAGGAGCCACGCAAGCTGACTGGCAGCACCGAGTGCCCAAGGAATACCACTCCAGAGAACGGAGAGTAAACCTAACCTTTCGGACCGTTTATCC
AGACCCAAGAGGAGCCCCCGGTGATACTTCTGCAGAGCTGCCACTGAGGTGAGGGCTGTGCACCCAGCAGCCCCTCCCCATCTCCCAGAAGCACTTCCAGAAGCTGCTGCGTGTACCTCCGTGATGTG
GCTGTTTGGAAATTGTGTTTGCTTCTCAGGTCCTATTCCTCCTGAATGAGAGCTACCAACACTTCATGCTGTCCGCATGTCTACTATAGGGACAGTTACTTGAGACAACTCTCTAAATCAAGGGTTGT
CCTTAGGCAAATTAAAAACTGCTCTGGCTGTGCTTACAGATGA

hide sequence

RefSeq Acc Id:

XM_039105432 ⟹ XP_038961360

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	100,410,870 - 100,429,466 (-)	NCBI
mRatBN7.2	3	79,955,889 - 79,972,820 (-)	NCBI

RefSeq Acc Id:

XM_039105433 ⟹ XP_038961361

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	100,394,942 - 100,429,466 (-)	NCBI
mRatBN7.2	3	79,939,518 - 79,972,032 (-)	NCBI

RefSeq Acc Id:

XM_063284151 ⟹ XP_063140221

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	100,412,375 - 100,429,466 (-)	NCBI


Protein RefSeqs	NP_001014202	(Get FASTA)	NCBI Sequence Viewer
	XP_006234647	(Get FASTA)	NCBI Sequence Viewer
	XP_038961360	(Get FASTA)	NCBI Sequence Viewer
	XP_038961361	(Get FASTA)	NCBI Sequence Viewer
	XP_063140221	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83756	(Get FASTA)	NCBI Sequence Viewer
	AHW98120	(Get FASTA)	NCBI Sequence Viewer
	EDL79602	(Get FASTA)	NCBI Sequence Viewer
	EDL79603	(Get FASTA)	NCBI Sequence Viewer
	EDL79604	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000030278.4
	ENSRNOP00000093084
GenBank Protein	Q5XIC8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001014202 ⟸ NM_001014180

- UniProtKB:

Q5XIC8 (UniProtKB/Swiss-Prot), A6HNK1 (UniProtKB/TrEMBL), A0A8I6AIA0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGDKRQRARVQGAWATPTKSQSAARPATPARSRPSQTPGPSWRSKEQQQCDRRFVFKEPQLVVRAAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDLKEADWILERLCQDVPWKQRMGIREDITYP
QPRLTAWYGELPYTYSRVTMEPNPHWLPVLWTLKSRIEENTGHTFNSLLCNFYRDEKDSVDWHSDDEPSLGSCPVIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQ
HRVPKEYHSRERRVNLTFRTVYPDPRGAPGDTSAELPLR

hide sequence

RefSeq Acc Id:	XP_006234647 ⟸ XM_006234585
- Peptide Label:	isoform X1
- UniProtKB:	Q5XIC8 (UniProtKB/Swiss-Prot), A6HNK1 (UniProtKB/TrEMBL), A0A8I6AIA0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGDKRQRARVQGAWATPTKSQSAARPATPARSRPSQTPGPSWRSKEQQQCDRRFVFKEPQLVVR AAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDLKEADWILERLCQDVPWKQRMGIREDITYPQPRLTAWYGELPYTYSRVTMEPNPHWLPVLWTLKSRIEENTGHTFNSLLCNFYRDEKDSVDWHS DDEPSLGSCPVIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSRERRVNLTFRTVYPDPRGAPGDTSAELPLR hide sequence

Ensembl Acc Id:

ENSRNOP00000030278 ⟸ ENSRNOT00000030784

RefSeq Acc Id:	XP_038961361 ⟸ XM_039105433
- Peptide Label:	isoform X3
- UniProtKB:	A6HNK3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961360 ⟸ XM_039105432
- Peptide Label:	isoform X2
- UniProtKB:	A0A158URU1 (UniProtKB/TrEMBL)

Protein Domains

Fe2OG dioxygenase

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XIC8-F1-model_v2	AlphaFold	Q5XIC8	1-295	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13692235

Promoter ID:

EPDNEW_R2760

Type:

multiple initiation site

Name:

Alkbh3_1

Description:

alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	82,906,594 - 82,906,654	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-48659	BioCyc
Ensembl Genes	ENSRNOG00000021678	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000030784.6	UniProtKB/Swiss-Prot
	ENSRNOT00000112362	ENTREZGENE
Gene3D-CATH	2.60.120.590	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7192721	IMAGE-MGC_LOAD
InterPro	AlkB-like	UniProtKB/Swiss-Prot
	AlkB-like_sf	UniProtKB/Swiss-Prot
	ALKBH3	UniProtKB/Swiss-Prot
	Oxoglu/Fe-dep_dioxygenase	UniProtKB/Swiss-Prot
KEGG Report	rno:362169	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94691	IMAGE-MGC_LOAD
NCBI Gene	362169	ENTREZGENE
PANTHER	ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3	UniProtKB/Swiss-Prot
	PTHR31212	UniProtKB/Swiss-Prot
Pfam	2OG-FeII_Oxy_2	UniProtKB/Swiss-Prot
PhenoGen	Alkbh3	PhenoGen
PROSITE	FE2OG_OXY	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000021678	RatGTEx
Superfamily-SCOP	Clavaminate synthase-like	UniProtKB/Swiss-Prot
UniProt	A0A158URU1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AIA0	ENTREZGENE, UniProtKB/TrEMBL
	A6HNK1	ENTREZGENE, UniProtKB/TrEMBL
	A6HNK3	ENTREZGENE, UniProtKB/TrEMBL
	ALKB3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-01	Alkbh3	alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase	Alkbh3	alkB, alkylation repair homolog 3 (E. coli)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Alkbh3	alkB, alkylation repair homolog 3 (E. coli)	LOC362169	similar to RIKEN cDNA 1810020C19 gene	Symbol and Name updated	1299863	APPROVED
2005-07-29	LOC362169	similar to RIKEN cDNA 1810020C19 gene			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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