Or4p18 (olfactory receptor family 4 subfamily P member 18) - Rat Genome Database

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Gene: Or4p18 (olfactory receptor family 4 subfamily P member 18) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or4p18
Name: olfactory receptor family 4 subfamily P member 18
RGD ID: 1333063
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 629; olfactory receptor gene Olr629; olfactory receptor Olr629; Olr629
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8394,456,430 - 94,457,380 (-)NCBIGRCr8
mRatBN7.2374,000,224 - 74,001,174 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl373,999,973 - 74,004,589 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx377,389,601 - 77,390,551 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0385,988,134 - 85,989,084 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0383,810,673 - 83,811,623 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0376,695,157 - 76,696,107 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl376,695,157 - 76,696,107 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0383,401,429 - 83,402,379 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4372,305,872 - 72,306,822 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1372,202,243 - 72,203,194 (-)NCBI
Celera373,277,014 - 73,277,964 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4p18Ratdetection of chemical stimulus involved in sensory perception of smell involved_inIEAGO:00049841600115GO_REF:0000108GOCGO_REF:0000108
Or4p18Ratdetection of chemical stimulus involved in sensory perception of smell  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or4p18RatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or4p18RatG protein-coupled receptor signaling pathway  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or4p18RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 and InterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or4p18Ratsensory perception of smell involved_inIEAUniProtKB-KW:KW-05521600115GO_REF:0000043UniProtGO_REF:0000043
Or4p18Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4p18Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Or4p18Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Or4p18Ratmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Or4p18Ratplasma membrane is_active_inIBAMGI:3030568 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or4p18Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Or4p18Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4p18RatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or4p18RatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Or4p18Ratolfactory receptor activity enablesIEAInterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or4p18Ratolfactory receptor activity  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or4p18Ratolfactory receptor activity enablesIBAMGI:3030568 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4p18Rattaste/olfaction phenotype  IEA 1303377 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline


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Variants in Or4p18
2 total Variants

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:69
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000044692
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 41 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat

1 to 10 of 41 rows





RefSeq Transcripts NM_001001058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000044692   ⟹   ENSRNOP00000049489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl376,695,157 - 76,696,107 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095330   ⟹   ENSRNOP00000090490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl373,999,973 - 74,004,589 (-)Ensembl
RefSeq Acc Id: NM_001001058   ⟹   NP_001001058
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8394,456,430 - 94,457,380 (-)NCBI
mRatBN7.2374,000,224 - 74,001,174 (-)NCBI
Rnor_6.0376,695,157 - 76,696,107 (-)NCBI
Rnor_5.0383,401,429 - 83,402,379 (-)NCBI
RGSC_v3.4372,305,872 - 72,306,822 (-)RGD
Celera373,277,014 - 73,277,964 (-)RGD
Sequence:
Protein RefSeqs NP_001001058 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000090490.1
  ENSRNOP00000109652
RefSeq Acc Id: NP_001001058   ⟸   NM_001001058
- UniProtKB: A0A8I6AEF3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000049489   ⟸   ENSRNOT00000044692
Ensembl Acc Id: ENSRNOP00000090490   ⟸   ENSRNOT00000095330
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZU6-F1-model_v2 AlphaFold D3ZZU6 1-316 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-48903 BioCyc
Ensembl Genes ENSRNOG00000047271 Ensembl
  ENSRNOG00000066461 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000078444 ENTREZGENE
Ensembl Transcript ENSRNOT00000095330.1 UniProtKB/TrEMBL
  ENSRNOT00000128905 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_Receptors UniProtKB/TrEMBL
KEGG Report rno:405946 UniProtKB/TrEMBL
NCBI Gene 405946 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or4p18 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047271 RatGTEx
  ENSRNOG00000066461 RatGTEx
  ENSRNOG00000078444 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6AEF3 ENTREZGENE, UniProtKB/TrEMBL
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or4p18  olfactory receptor family 4 subfamily P member 18  Olr629  olfactory receptor 629  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr629  olfactory receptor 629   Olr629_predicted  olfactory receptor 629 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr629_predicted  olfactory receptor 629 (predicted)      Symbol and Name status set to approved 70820 APPROVED