Or2t47e (olfactory receptor family 2 subfamily T member 47E) - Rat Genome Database

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Gene: Or2t47e (olfactory receptor family 2 subfamily T member 47E) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or2t47e
Name: olfactory receptor family 2 subfamily T member 47E
RGD ID: 1333061
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be active in plasma membrane. Orthologous to human OR2T29 (olfactory receptor family 2 subfamily T member 29); OR2T4 (olfactory receptor family 2 subfamily T member 4); and OR2T5 (olfactory receptor family 2 subfamily T member 5); INTERACTS WITH 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1421; olfactory receptor gene Olr1421; olfactory receptor Olr1421; Olr1421
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81043,342,909 - 43,343,871 (-)NCBIGRCr8
mRatBN7.21042,842,492 - 42,843,454 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1042,840,205 - 42,846,351 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1047,498,588 - 47,499,550 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01046,989,036 - 46,989,998 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01042,492,538 - 42,493,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01044,081,351 - 44,082,313 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1044,081,351 - 44,082,313 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01043,888,786 - 43,889,748 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41044,309,428 - 44,310,390 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11044,323,050 - 44,324,013 (-)NCBI
Celera1042,128,974 - 42,129,936 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or2t47eRat1,2-dimethylhydrazine multiple interactionsEXP 6480464[APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in decreased expression of OR2T47E mRNACTDPMID:27840820


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or2t47eRatdetection of chemical stimulus involved in sensory perception of smell involved_inIBAMGI:106182 and PANTHER:PTN0028180001600115GO_REF:0000033GO_CentralGO_REF:0000033
Or2t47eRatdetection of chemical stimulus involved in sensory perception of smell  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or2t47eRatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or2t47eRatG protein-coupled receptor signaling pathway  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or2t47eRatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 and InterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or2t47eRatsensory perception of smell involved_inIEAUniProtKB-KW:KW-05521600115GO_REF:0000043UniProtGO_REF:0000043
Or2t47eRatsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or2t47eRatmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Or2t47eRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Or2t47eRatplasma membrane is_active_inIBAMGI:106648 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or2t47eRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Or2t47eRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or2t47eRatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or2t47eRatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Or2t47eRatolfactory receptor activity enablesIBAMGI:106182 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or2t47eRatolfactory receptor activity  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or2t47eRatolfactory receptor activity enablesIEAInterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or2t47eRattaste/olfaction phenotype  IEA 1303377 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


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Variants in Or2t47e
4 total Variants

Predicted Target Of
Summary Value
Count of predictions:8
Count of miRNA genes:8
Interacting mature miRNAs:8
Transcripts:ENSRNOT00000051126
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 63 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103571058068663659Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat

1 to 10 of 63 rows



appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
mesoderm
nervous system
reproductive system
1 4 4 5 1 1 1 6 4 4 24


RefSeq Transcripts NM_001000780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC097901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000051126   ⟹   ENSRNOP00000050734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1044,081,351 - 44,082,313 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095789   ⟹   ENSRNOP00000096176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1042,840,205 - 42,846,351 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097330   ⟹   ENSRNOP00000094664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1042,840,205 - 42,844,536 (-)Ensembl
RefSeq Acc Id: NM_001000780   ⟹   NP_001000780
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81043,342,909 - 43,343,871 (-)NCBI
mRatBN7.21042,842,492 - 42,843,454 (-)NCBI
Rnor_6.01044,081,351 - 44,082,313 (-)NCBI
Rnor_5.01043,888,786 - 43,889,748 (-)NCBI
RGSC_v3.41044,309,428 - 44,310,390 (-)RGD
Celera1042,128,974 - 42,129,936 (-)RGD
Sequence:
Protein RefSeqs NP_001000780 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000039350
  ENSRNOP00000094664.1
  ENSRNOP00000096176.1
RefSeq Acc Id: NP_001000780   ⟸   NM_001000780
- UniProtKB: A0A8I6B3T7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000050734   ⟸   ENSRNOT00000051126
Ensembl Acc Id: ENSRNOP00000094664   ⟸   ENSRNOT00000097330
Ensembl Acc Id: ENSRNOP00000096176   ⟸   ENSRNOT00000095789
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZF09-F1-model_v2 AlphaFold D3ZF09 1-320 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-24974 BioCyc
Ensembl Genes ENSRNOG00000050694 Ensembl
  ENSRNOG00000067204 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000076869 ENTREZGENE
Ensembl Transcript ENSRNOT00000045318 ENTREZGENE
  ENSRNOT00000095789.1 UniProtKB/TrEMBL
  ENSRNOT00000097330.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:405057 UniProtKB/TrEMBL
NCBI Gene 405057 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or2t47e PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050694 RatGTEx
  ENSRNOG00000067204 RatGTEx
  ENSRNOG00000076869 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6B3T7 ENTREZGENE, UniProtKB/TrEMBL
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or2t47e  olfactory receptor family 2 subfamily T member 47E  Olr1421  olfactory receptor 1421  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1421  olfactory receptor 1421   Olr1421_predicted  olfactory receptor 1421 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1421_predicted  olfactory receptor 1421 (predicted)      Symbol and Name status set to approved 70820 APPROVED