Symbol:
Kif14
Name:
kinesin family member 14
RGD ID:
1310650
Description:
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and PDZ domain binding activity. Predicted to be involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; brain development; and regulation of cell cycle process. Predicted to act upstream of or within several processes, including negative regulation of integrin activation; regulation of Rap protein signal transduction; and substrate adhesion-dependent cell spreading. Predicted to be located in several cellular components, including Flemming body; cytosol; and spindle midzone. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm and microtubule. Human ortholog(s) of this gene implicated in Meckel syndrome and primary autosomal recessive microcephaly 20. Orthologous to human KIF14 (kinesin family member 14); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
kinesin-like protein KIF14; LOC360849
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
KIF14 (kinesin family member 14)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):
Kif14 (kinesin family member 14)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Kif14 (kinesin family member 14)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
KIF14 (kinesin family member 14)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
KIF14 (kinesin family member 14)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Kif14 (kinesin family member 14)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
KIF14 (kinesin family member 14)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
KIF14 (kinesin family member 14)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Kif14 (kinesin family member 14)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
CRYBB2 (crystallin beta B2)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
KIF14 (kinesin family member 14)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Kif14 (kinesin family member 14)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
kif14 (kinesin family member 14)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
neb
Alliance
DIOPT (Ensembl Compara|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
kif14
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 13 50,478,646 - 50,542,256 (+) NCBI GRCr8 mRatBN7.2 13 47,926,975 - 47,990,598 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 13 47,927,044 - 47,989,164 (+) Ensembl mRatBN7.2 Ensembl Rnor_6.0 13 53,350,073 - 53,421,992 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 53,351,717 - 53,420,111 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 13 58,400,186 - 58,466,702 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 13 49,514,095 - 49,576,012 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 13 49,509,198 - 49,592,154 (+) NCBI Celera 13 48,238,110 - 48,300,358 (+) NCBI Celera Cytogenetic Map 13 q13 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Kif14 Rat (-)-epigallocatechin 3-gallate multiple interactions ISO KIF14 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIF14 mRNA CTD PMID:22079256 Kif14 Rat (1->4)-beta-D-glucan multiple interactions ISO Kif14 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of KIF14 mRNA CTD PMID:36331819 Kif14 Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of KIF14 mRNA CTD PMID:30723492 Kif14 Rat 17beta-estradiol increases expression ISO KIF14 (Homo sapiens) 6480464 Estradiol results in increased expression of KIF14 mRNA CTD PMID:16474171 and PMID:19167446 Kif14 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO KIF14 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of KIF14 mRNA CTD PMID:20106945 and PMID:21632981 Kif14 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of KIF14 mRNA CTD PMID:33387578 Kif14 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO KIF14 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of KIF14 mRNA CTD PMID:22574217 Kif14 Rat 2-palmitoylglycerol increases expression ISO KIF14 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of KIF14 mRNA CTD PMID:37199045 Kif14 Rat 5-fluorouracil decreases expression ISO KIF14 (Homo sapiens) 6480464 Fluorouracil results in decreased expression of KIF14 mRNA CTD PMID:34151400 Kif14 Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of KIF14 mRNA CTD PMID:28959563 Kif14 Rat aflatoxin B1 affects expression ISO KIF14 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of KIF14 protein CTD PMID:20106945 Kif14 Rat aflatoxin B1 decreases expression ISO KIF14 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of KIF14 mRNA CTD PMID:32234424 Kif14 Rat aflatoxin B1 increases methylation ISO KIF14 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of KIF14 gene CTD PMID:27153756 Kif14 Rat all-trans-retinoic acid decreases expression ISO KIF14 (Homo sapiens) 6480464 Tretinoin results in decreased expression of KIF14 mRNA CTD PMID:33167477 Kif14 Rat antimycin A increases expression ISO KIF14 (Homo sapiens) 6480464 Antimycin A results in increased expression of KIF14 mRNA CTD PMID:33512557 Kif14 Rat aristolochic acid A decreases expression ISO KIF14 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of KIF14 mRNA and aristolochic acid I results in decreased expression of KIF14 protein CTD PMID:33212167 Kif14 Rat arsenite(3-) multiple interactions ISO KIF14 (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to KIF14 mRNA] CTD PMID:32406909 Kif14 Rat azoxystrobin increases expression ISO KIF14 (Homo sapiens) 6480464 azoxystrobin results in increased expression of KIF14 mRNA CTD PMID:33512557 Kif14 Rat benzo[a]pyrene increases expression ISO Kif14 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of KIF14 mRNA CTD PMID:32417428 Kif14 Rat benzo[a]pyrene diol epoxide I decreases expression ISO KIF14 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 more ... Kif14 Rat bis(2-chloroethyl) sulfide decreases expression ISO KIF14 (Homo sapiens) 6480464 Mustard Gas results in decreased expression of KIF14 mRNA CTD PMID:25102026 Kif14 Rat bisphenol A increases expression ISO KIF14 (Homo sapiens) 6480464 bisphenol A results in increased expression of KIF14 mRNA CTD PMID:16474171 Kif14 Rat bisphenol A multiple interactions ISO KIF14 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of KIF14 gene CTD PMID:31601247 Kif14 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of KIF14 mRNA CTD PMID:32145629 Kif14 Rat bisphenol A decreases expression ISO KIF14 (Homo sapiens) 6480464 bisphenol A results in decreased expression of KIF14 mRNA CTD PMID:29275510 Kif14 Rat bisphenol A decreases methylation ISO Kif14 (Mus musculus) 6480464 bisphenol A results in decreased methylation of KIF14 promoter CTD PMID:27312807 Kif14 Rat butanal decreases expression ISO KIF14 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of KIF14 mRNA CTD PMID:26079696 Kif14 Rat cadmium atom decreases expression ISO KIF14 (Homo sapiens) 6480464 Cadmium results in decreased expression of KIF14 mRNA CTD PMID:24376830 Kif14 Rat cadmium dichloride increases expression ISO KIF14 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of KIF14 mRNA CTD PMID:38382870 Kif14 Rat cadmium dichloride decreases expression ISO KIF14 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of KIF14 mRNA CTD PMID:38568856 Kif14 Rat calcitriol decreases expression ISO KIF14 (Homo sapiens) 6480464 Calcitriol results in decreased expression of KIF14 mRNA CTD PMID:21592394 Kif14 Rat calcitriol multiple interactions ISO KIF14 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of KIF14 mRNA CTD PMID:21592394 Kif14 Rat chlorpyrifos decreases expression ISO Kif14 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of KIF14 mRNA CTD PMID:37019170 Kif14 Rat chromium(6+) multiple interactions ISO KIF14 (Homo sapiens) 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of KIF14 mRNA CTD PMID:38479592 Kif14 Rat cisplatin multiple interactions ISO KIF14 (Homo sapiens) 6480464 Cisplatin promotes the reaction [Piroxicam results in decreased expression of KIF14 mRNA] CTD PMID:21858171 Kif14 Rat cisplatin decreases expression ISO KIF14 (Homo sapiens) 6480464 Cisplatin results in decreased expression of KIF14 mRNA CTD PMID:27594783 Kif14 Rat cobalt dichloride decreases expression ISO KIF14 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of KIF14 mRNA CTD PMID:19376846 Kif14 Rat coumestrol multiple interactions ISO KIF14 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:18310284 and PMID:19167446 Kif14 Rat coumestrol increases expression ISO KIF14 (Homo sapiens) 6480464 Coumestrol results in increased expression of KIF14 mRNA CTD PMID:19167446 Kif14 Rat cyclosporin A decreases expression ISO KIF14 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of KIF14 mRNA CTD PMID:20106945 more ... Kif14 Rat DDE increases expression ISO KIF14 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of KIF14 mRNA CTD PMID:38568856 Kif14 Rat diallyl trisulfide decreases expression ISO KIF14 (Homo sapiens) 6480464 diallyl trisulfide results in decreased expression of KIF14 mRNA CTD PMID:34995734 Kif14 Rat disodium selenite decreases expression ISO KIF14 (Homo sapiens) 6480464 Sodium Selenite results in decreased expression of KIF14 mRNA CTD PMID:24383545 Kif14 Rat doxorubicin decreases expression ISO KIF14 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of KIF14 mRNA CTD PMID:30031762 Kif14 Rat Enterolactone multiple interactions ISO KIF14 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of KIF14 mRNA CTD PMID:19167446 Kif14 Rat folic acid multiple interactions ISO KIF14 (Homo sapiens) 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of KIF14 mRNA CTD PMID:24657277 Kif14 Rat formaldehyde decreases expression ISO KIF14 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of KIF14 mRNA CTD PMID:23649840 Kif14 Rat FR900359 decreases phosphorylation ISO KIF14 (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of KIF14 protein CTD PMID:37730182 Kif14 Rat fulvestrant multiple interactions ISO KIF14 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of KIF14 gene CTD PMID:31601247 Kif14 Rat genistein increases expression ISO KIF14 (Homo sapiens) 6480464 Genistein results in increased expression of KIF14 mRNA CTD PMID:16474171 Kif14 Rat indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of KIF14 mRNA CTD PMID:21396975 Kif14 Rat irinotecan decreases expression ISO KIF14 (Homo sapiens) 6480464 Irinotecan analog results in decreased expression of KIF14 mRNA CTD PMID:18927307 Kif14 Rat ivermectin decreases expression ISO KIF14 (Homo sapiens) 6480464 Ivermectin results in decreased expression of KIF14 protein CTD PMID:32959892 Kif14 Rat leflunomide decreases expression ISO KIF14 (Homo sapiens) 6480464 leflunomide results in decreased expression of KIF14 mRNA CTD PMID:28988120 Kif14 Rat lidocaine increases expression EXP 6480464 Lidocaine results in increased expression of KIF14 mRNA CTD PMID:35283115 Kif14 Rat lipopolysaccharide multiple interactions ISO KIF14 (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of KIF14 mRNA CTD PMID:35811015 Kif14 Rat lucanthone decreases expression ISO KIF14 (Homo sapiens) 6480464 Lucanthone results in decreased expression of KIF14 mRNA CTD PMID:21148553 Kif14 Rat methotrexate multiple interactions ISO KIF14 (Homo sapiens) 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of KIF14 mRNA CTD PMID:24657277 Kif14 Rat methyl methanesulfonate decreases expression ISO KIF14 (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of KIF14 mRNA CTD PMID:23649840 Kif14 Rat N-methyl-4-phenylpyridinium decreases expression ISO KIF14 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of KIF14 mRNA CTD PMID:24810058 Kif14 Rat N-Nitrosopyrrolidine decreases expression ISO KIF14 (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in decreased expression of KIF14 mRNA CTD PMID:32234424 Kif14 Rat nickel atom increases expression ISO KIF14 (Homo sapiens) 6480464 Nickel results in increased expression of KIF14 mRNA CTD PMID:25583101 Kif14 Rat ozone increases expression ISO Kif14 (Mus musculus) 6480464 Ozone results in increased expression of KIF14 mRNA CTD PMID:31626304 Kif14 Rat ozone multiple interactions ISO Kif14 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of KIF14 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of KIF14 mRNA CTD PMID:27106289 and PMID:34911549 Kif14 Rat palbociclib decreases expression ISO KIF14 (Homo sapiens) 6480464 palbociclib results in decreased expression of KIF14 mRNA CTD PMID:22869556 Kif14 Rat paracetamol increases expression ISO KIF14 (Homo sapiens) 6480464 Acetaminophen results in increased expression of KIF14 mRNA CTD PMID:22230336 Kif14 Rat paracetamol increases expression ISO Kif14 (Mus musculus) 6480464 Acetaminophen results in increased expression of KIF14 mRNA CTD PMID:34724096 Kif14 Rat paraquat multiple interactions ISO Kif14 (Mus musculus) 6480464 [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of KIF14 mRNA CTD PMID:28012437 Kif14 Rat perfluorononanoic acid decreases expression ISO KIF14 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of KIF14 mRNA CTD PMID:32588087 Kif14 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Kif14 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of KIF14 mRNA CTD PMID:36331819 Kif14 Rat perfluorooctanoic acid decreases expression ISO KIF14 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of KIF14 mRNA CTD PMID:36326898 Kif14 Rat pirinixic acid multiple interactions ISO Kif14 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of KIF14 mRNA CTD PMID:19710929 Kif14 Rat pirinixic acid increases expression ISO Kif14 (Mus musculus) 6480464 pirinixic acid results in increased expression of KIF14 mRNA CTD PMID:20813756 Kif14 Rat piroxicam multiple interactions ISO KIF14 (Homo sapiens) 6480464 Cisplatin promotes the reaction [Piroxicam results in decreased expression of KIF14 mRNA] CTD PMID:21858171 Kif14 Rat piroxicam decreases expression ISO KIF14 (Homo sapiens) 6480464 Piroxicam results in decreased expression of KIF14 mRNA CTD PMID:21858171 Kif14 Rat potassium chromate multiple interactions ISO KIF14 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIF14 mRNA CTD PMID:22079256 Kif14 Rat potassium chromate decreases expression ISO KIF14 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of KIF14 mRNA CTD PMID:22079256 Kif14 Rat progesterone decreases expression ISO KIF14 (Homo sapiens) 6480464 Progesterone results in decreased expression of KIF14 mRNA CTD PMID:21795739 Kif14 Rat propanal decreases expression ISO KIF14 (Homo sapiens) 6480464 propionaldehyde results in decreased expression of KIF14 mRNA CTD PMID:26079696 Kif14 Rat quercetin decreases expression ISO KIF14 (Homo sapiens) 6480464 Quercetin results in decreased expression of KIF14 mRNA CTD PMID:21632981 Kif14 Rat resveratrol multiple interactions ISO KIF14 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of KIF14 mRNA CTD PMID:19167446 Kif14 Rat rotenone increases expression ISO KIF14 (Homo sapiens) 6480464 Rotenone results in increased expression of KIF14 mRNA CTD PMID:33512557 Kif14 Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO KIF14 (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of KIF14 mRNA CTD PMID:35811015 Kif14 Rat silicon dioxide increases expression ISO Kif14 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of KIF14 mRNA CTD PMID:29341224 Kif14 Rat silicon dioxide increases methylation ISO KIF14 (Homo sapiens) 6480464 Silicon Dioxide results in increased methylation of KIF14 gene CTD PMID:34973136 Kif14 Rat sodium arsenite affects expression ISO KIF14 (Homo sapiens) 6480464 sodium arsenite affects the expression of KIF14 mRNA CTD PMID:29301061 Kif14 Rat sulforaphane increases expression ISO KIF14 (Homo sapiens) 6480464 sulforaphane results in increased expression of KIF14 mRNA CTD PMID:31838189 Kif14 Rat sulindac increases expression ISO KIF14 (Homo sapiens) 6480464 Sulindac results in increased expression of KIF14 mRNA CTD PMID:11906190 Kif14 Rat sunitinib decreases expression ISO KIF14 (Homo sapiens) 6480464 Sunitinib results in decreased expression of KIF14 mRNA CTD PMID:31533062 Kif14 Rat testosterone multiple interactions ISO KIF14 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of KIF14 mRNA CTD PMID:21592394 Kif14 Rat testosterone decreases expression ISO KIF14 (Homo sapiens) 6480464 Testosterone results in decreased expression of KIF14 mRNA CTD PMID:21592394 and PMID:33359661 Kif14 Rat titanium dioxide increases methylation ISO Kif14 (Mus musculus) 6480464 titanium dioxide results in increased methylation of KIF14 promoter CTD PMID:35295148 Kif14 Rat titanium dioxide decreases methylation ISO Kif14 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of KIF14 promoter CTD PMID:35295148 Kif14 Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of KIF14 mRNA CTD PMID:33387578 Kif14 Rat triclosan decreases expression ISO KIF14 (Homo sapiens) 6480464 Triclosan results in decreased expression of KIF14 mRNA CTD PMID:30510588 Kif14 Rat trimellitic anhydride increases expression ISO Kif14 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of KIF14 mRNA CTD PMID:19042947 Kif14 Rat triptonide increases expression ISO Kif14 (Mus musculus) 6480464 triptonide results in increased expression of KIF14 mRNA CTD PMID:33045310 Kif14 Rat troglitazone decreases expression ISO KIF14 (Homo sapiens) 6480464 troglitazone results in decreased expression of KIF14 mRNA CTD PMID:19140230 Kif14 Rat trovafloxacin decreases expression ISO Kif14 (Mus musculus) 6480464 trovafloxacin results in decreased expression of KIF14 mRNA CTD PMID:35537566 Kif14 Rat tungsten decreases expression ISO Kif14 (Mus musculus) 6480464 Tungsten results in decreased expression of KIF14 mRNA CTD PMID:30912803 Kif14 Rat tunicamycin increases expression ISO KIF14 (Homo sapiens) 6480464 Tunicamycin results in increased expression of KIF14 mRNA CTD PMID:33545341 Kif14 Rat valproic acid decreases expression ISO KIF14 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of KIF14 mRNA CTD PMID:28001369 Kif14 Rat vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of KIF14 gene CTD PMID:31079544
Biological Process
activation of protein kinase activity (ISO) cell division (IEA,ISO) cell proliferation in forebrain (IEA,ISO) cerebellar cortex development (IEA,ISO) cerebellar granular layer structural organization (IEA,ISO) cerebellar Purkinje cell layer structural organization (IEA,ISO) cerebral cortex development (IEA,ISO) establishment of protein localization (IEA,ISO) hippocampus development (IEA,ISO) microtubule depolymerization (ISO) microtubule-based movement (IBA,IEA) mitotic metaphase chromosome alignment (IEA,ISO) negative regulation of apoptotic process (IEA,ISO) negative regulation of integrin activation (IEA,ISO) negative regulation of neuron apoptotic process (IEA,ISO) olfactory bulb development (IEA,ISO) positive regulation of cell population proliferation (IEA,ISO) positive regulation of cytokinesis (IEA,ISO) proteasome-mediated ubiquitin-dependent protein catabolic process (IEA,ISO) regulation of cell adhesion (IEA,ISO) regulation of cell growth (IEA,ISO) regulation of cell maturation (IEA,ISO) regulation of cell migration (IEA,ISO) regulation of G1/S transition of mitotic cell cycle (IEA,ISO) regulation of G2/M transition of mitotic cell cycle (IEA,ISO) regulation of myelination (IEA,ISO) regulation of neuron apoptotic process (IEA,ISO) regulation of Rap protein signal transduction (IEA,ISO) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (IEA,ISO) substrate adhesion-dependent cell spreading (IEA,ISO)
Molecular Function
ATP binding (IEA,ISO) ATP hydrolysis activity (IBA,IEA,ISO) cytoskeletal motor activity (IEA) microtubule binding (IBA,IEA,ISO) microtubule motor activity (IBA,IEA) nucleotide binding (IEA) PDZ domain binding (IEA,ISO) plus-end-directed microtubule motor activity (IEA,ISO) protein binding (ISO) protein kinase binding (IEA,ISO) tubulin binding (IEA,ISO)
Kif14 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 13 50,478,646 - 50,542,256 (+) NCBI GRCr8 mRatBN7.2 13 47,926,975 - 47,990,598 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 13 47,927,044 - 47,989,164 (+) Ensembl mRatBN7.2 Ensembl Rnor_6.0 13 53,350,073 - 53,421,992 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 53,351,717 - 53,420,111 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 13 58,400,186 - 58,466,702 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 13 49,514,095 - 49,576,012 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 13 49,509,198 - 49,592,154 (+) NCBI Celera 13 48,238,110 - 48,300,358 (+) NCBI Celera Cytogenetic Map 13 q13 NCBI
KIF14 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 1 200,551,497 - 200,620,751 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 1 200,551,497 - 200,620,751 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 1 200,520,625 - 200,589,879 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 1 198,787,930 - 198,856,485 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 1 197,252,963 - 197,321,519 NCBI Celera 1 173,643,207 - 173,712,428 (-) NCBI Celera Cytogenetic Map 1 q32.1 NCBI HuRef 1 171,687,033 - 171,756,258 (-) NCBI HuRef CHM1_1 1 201,943,245 - 202,012,495 (-) NCBI CHM1_1 T2T-CHM13v2.0 1 199,808,434 - 199,877,845 (-) NCBI T2T-CHM13v2.0
Kif14 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 1 136,394,044 - 136,483,676 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 1 136,394,081 - 136,459,249 (+) Ensembl GRCm39 Ensembl GRCm38 1 136,466,301 - 136,555,938 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 1 136,466,343 - 136,531,511 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 1 138,364,535 - 138,428,088 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 1 138,284,369 - 138,347,922 (+) NCBI MGSCv36 mm8 Celera 1 139,105,105 - 139,173,763 (+) NCBI Celera Cytogenetic Map 1 E4 NCBI cM Map 1 59.8 NCBI
Kif14 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955406 36,737,484 - 36,791,756 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955406 36,732,135 - 36,791,756 (-) NCBI ChiLan1.0 ChiLan1.0
KIF14 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 1 48,757,123 - 48,825,143 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 1 48,720,667 - 48,788,642 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 1 176,156,870 - 176,223,093 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 1 180,462,381 - 180,528,302 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 1 180,462,578 - 180,526,323 (-) Ensembl panpan1.1 panPan2
KIF14 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 7 2,548,407 - 2,602,371 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 7 2,548,258 - 2,601,581 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 7 2,221,247 - 2,287,287 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 7 2,195,400 - 2,250,507 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 7 2,195,260 - 2,249,717 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 7 2,167,231 - 2,233,487 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 7 2,268,791 - 2,334,912 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 7 2,299,753 - 2,366,285 (+) NCBI UU_Cfam_GSD_1.0
Kif14 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
KIF14 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 10 23,123,480 - 23,174,273 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 10 23,123,379 - 23,177,919 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 10 27,601,816 - 27,655,240 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
KIF14 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 25 28,789,952 - 28,856,713 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 25 28,789,614 - 28,856,570 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666055 29,591,469 - 29,660,607 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Kif14 (Heterocephalus glaber - naked mole-rat)
.
Predicted Target Of
Count of predictions: 31 Count of miRNA genes: 30 Interacting mature miRNAs: 31 Transcripts: ENSRNOT00000012038 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
1298066 Bp159 Blood pressure QTL 159 0.004 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 46088046 91088046 Rat 10755495 Bp387 Blood pressure QTL 387 3.78 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 34663461 87525369 Rat 9589141 Insul28 Insulin level QTL 28 10.82 0.001 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 13 9313465 54313465 Rat 6893344 Cm79 Cardiac mass QTL 79 1.5 0.04 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 13 43720770 62022792 Rat 70220 Bp55 Blood pressure QTL 55 5.75 arterial blood pressure trait (VT:2000000) blood pressure measurement (CMO:0000003) 13 37374509 82374509 Rat 71119 Thym2 Thymus enlargement QTL 2 3.8 thymus mass (VT:0004954) thymus weight to body weight ratio (CMO:0000612) 13 46197976 84753113 Rat 61391 Bp5 Blood pressure QTL 5 5.6 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 13 22301875 67301875 Rat 4889861 Pur29 Proteinuria QTL 29 13.8 0.005 urine total protein amount (VT:0000032) urine total protein excretion rate (CMO:0000756) 13 37415584 80753406 Rat 2317040 Aia21 Adjuvant induced arthritis QTL 21 2.75 joint integrity trait (VT:0010548) left rear ankle joint diameter (CMO:0002149) 13 9831541 54831541 Rat 631645 Bp121 Blood pressure QTL 121 3.3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 14915655 59915655 Rat 2317046 Aia8 Adjuvant induced arthritis QTL 8 3.9700000286102295 joint integrity trait (VT:0010548) left rear ankle joint diameter (CMO:0002149) 13 9831541 54831541 Rat 12879441 Bp396 Blood pressure QTL 396 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 13 45699983 90699983 Rat 619615 Bp80 Blood pressure QTL 80 0.0354 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 39754544 84754544 Rat 1581570 Eae17 Experimental allergic encephalomyelitis QTL 17 4.1 nervous system integrity trait (VT:0010566) experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046) 13 8897350 101631289 Rat 70170 Eae14 Experimental allergic encephalomyelitis QTL 14 0.0024 nervous system integrity trait (VT:0010566) experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046) 13 23203448 68203448 Rat 1331784 Bp222 Blood pressure QTL 222 2.944 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 13 17694436 53050594 Rat 61340 Bp25 Blood pressure QTL 25 4.2 0.004 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 34535218 79535218 Rat 1581573 Uae36 Urinary albumin excretion QTL 36 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 13 5994833 77046787 Rat 1549897 Stresp12 Stress response QTL 12 3.35 stress-related behavior trait (VT:0010451) number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960) 13 38433408 83433408 Rat 7207885 Glom27 Glomerulus QTL 27 3.9 kidney glomerulus integrity trait (VT:0010546) kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139) 13 20605871 101339738 Rat 1558644 Cm45 Cardiac mass QTL 45 3.6 0.002 heart mass (VT:0007028) heart wet weight (CMO:0000069) 13 23692969 68692969 Rat 70181 BpQTLcluster11 Blood pressure QTL cluster 11 6.922 arterial blood pressure trait (VT:2000000) absolute change in mean arterial blood pressure (CMO:0000533) 13 31241331 93395974 Rat 61349 Bp31 Blood pressure QTL 31 5.75 arterial blood pressure trait (VT:2000000) blood pressure measurement (CMO:0000003) 13 37374509 82374509 Rat 2303563 Bw89 Body weight QTL 89 6 body mass (VT:0001259) body weight (CMO:0000012) 13 32284471 77284471 Rat 1354621 Rf47 Renal function QTL 47 3.7 kidney renin amount (VT:0010559) kidney renin level (CMO:0002166) 13 30395351 101056920 Rat 2301962 Cm72 Cardiac mass QTL 72 4.12 heart left ventricle mass (VT:0007031) heart left ventricle weight (CMO:0000776) 13 31241331 58363171 Rat 1581554 Pur11 Proteinuria QTL 11 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 13 5994833 77046787 Rat 12879477 Bp401 Blood pressure QTL 401 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 13 37262092 82262092 Rat 1331750 Bp220 Blood pressure QTL 220 2.98 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 13 37415584 82415584 Rat 6893338 Cm76 Cardiac mass QTL 76 0 0.99 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 13 23692969 68692969 Rat 1354666 Bp244 Blood pressure QTL 244 4.9 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 13 1 101056920 Rat 9589164 Gluco66 Glucose level QTL 66 6.67 0.001 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 13 15158722 60158722 Rat 7411662 Foco29 Food consumption QTL 29 20.8 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 13 9313465 54313465 Rat
AU049182
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 13 47,956,867 - 47,957,164 (+) MAPPER mRatBN7.2 mRatBN7.2 16 79,362,320 - 79,363,905 (+) MAPPER mRatBN7.2 Rnor_6.0 16 85,175,580 - 85,177,164 NCBI Rnor6.0 Rnor_6.0 13 53,381,304 - 53,381,598 NCBI Rnor6.0 Rnor_5.0 16 84,615,001 - 84,616,585 UniSTS Rnor5.0 Rnor_5.0 13 58,430,632 - 58,430,926 UniSTS Rnor5.0 RGSC_v3.4 13 49,542,734 - 49,543,028 UniSTS RGSC3.4 RGSC_v3.4 16 84,722,568 - 84,724,154 UniSTS RGSC3.4 Celera 16 77,149,496 - 77,151,080 UniSTS Celera 13 48,267,324 - 48,267,584 UniSTS Cytogenetic Map 13 q13 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
9
45
108
86
85
54
25
54
6
204
91
88
42
60
31
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Ensembl Acc Id:
ENSRNOT00000012038 ⟹ ENSRNOP00000012038
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 13 47,927,044 - 47,989,164 (+) Ensembl Rnor_6.0 Ensembl 13 53,351,717 - 53,420,111 (+) Ensembl
RefSeq Acc Id:
NM_001427233 ⟹ NP_001414162
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 13 50,480,211 - 50,542,256 (+) NCBI
RefSeq Acc Id:
XM_039091329 ⟹ XP_038947257
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 13 50,478,649 - 50,542,256 (+) NCBI mRatBN7.2 13 47,926,975 - 47,990,598 (+) NCBI
RefSeq Acc Id:
XM_063272468 ⟹ XP_063128538
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 13 50,478,646 - 50,535,336 (+) NCBI
Ensembl Acc Id:
ENSRNOP00000012038 ⟸ ENSRNOT00000012038
RefSeq Acc Id:
XP_038947257 ⟸ XM_039091329
- Peptide Label:
isoform X1
- UniProtKB:
D3ZE01 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063128538 ⟸ XM_063272468
- Peptide Label:
isoform X2
RefSeq Acc Id:
NP_001414162 ⟸ NM_001427233
- UniProtKB:
D3ZE01 (UniProtKB/TrEMBL)
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2008-04-30
Kif14
kinesin family member 14
Kif14_predicted
kinesin family member 14 (predicted)
'predicted' is removed
2292626
APPROVED
2005-01-12
Kif14_predicted
kinesin family member 14 (predicted)
Symbol and Name status set to approved
70820
APPROVED