Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Taf5l1 | Rat | (+)-catechin | multiple interactions | ISO | TAF5L (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of TAF5L mRNA | CTD | PMID:24763279 | Taf5l1 | Rat | (-)-demecolcine | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of TAF5L mRNA | CTD | PMID:23649840 | Taf5l1 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Taf5l (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of TAF5L mRNA | CTD | PMID:22206623 | Taf5l1 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Taf5l (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of TAF5L mRNA | CTD | PMID:17555576 | Taf5l1 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Taf5l (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TAF5L mRNA | CTD | PMID:17942748 | Taf5l1 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Taf5l (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of TAF5L mRNA | CTD | PMID:17942748 | Taf5l1 | Rat | 17beta-estradiol | multiple interactions | ISO | TAF5L (Homo sapiens) | 6480464 | EGF protein promotes the reaction [Estradiol results in increased expression of TAF5L mRNA] | CTD | PMID:24758408 | Taf5l1 | Rat | 17beta-estradiol | increases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Estradiol results in increased expression of TAF5L mRNA | CTD | PMID:24758408 | Taf5l1 | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of TAF5L mRNA | CTD | PMID:29581250 | Taf5l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Taf5l (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TAF5L mRNA and [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in increased methylation of TAF5L gene | CTD | PMID:17942748 and PMID:21212295 | Taf5l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TAF5L mRNA | CTD | PMID:33387578 | Taf5l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases methylation | ISO | Taf5l (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased methylation of TAF5L gene | CTD | PMID:21212295 | Taf5l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Taf5l (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TAF5L mRNA | CTD | PMID:21570461 | Taf5l1 | Rat | 3,3',5-triiodo-L-thyronine | increases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Triiodothyronine results in increased expression of TAF5L mRNA | CTD | PMID:23397585 | Taf5l1 | Rat | 5-fluorouracil | multiple interactions | ISO | TAF5L (Homo sapiens) | 6480464 | [Fluorouracil co-treated with irinotecan] results in decreased expression of TAF5L mRNA | CTD | PMID:16391804 | Taf5l1 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of TAF5L mRNA | CTD | PMID:28959563 | Taf5l1 | Rat | aflatoxin B1 | increases methylation | ISO | TAF5L (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of TAF5L gene | CTD | PMID:27153756 | Taf5l1 | Rat | amiodarone | increases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Amiodarone results in increased expression of TAF5L mRNA | CTD | PMID:19774075 | Taf5l1 | Rat | benzo[a]pyrene | decreases methylation | ISO | TAF5L (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of TAF5L 5' UTR | CTD | PMID:27901495 | Taf5l1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TAF5L mRNA | CTD | PMID:25181051 | Taf5l1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TAF5L mRNA | CTD | PMID:30816183 and PMID:32528016 | Taf5l1 | Rat | bisphenol A | affects methylation | ISO | Taf5l (Mus musculus) | 6480464 | bisphenol A affects the methylation of TAF5L promoter | CTD | PMID:27334623 | Taf5l1 | Rat | butanal | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of TAF5L mRNA | CTD | PMID:26079696 | Taf5l1 | Rat | copper(II) sulfate | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of TAF5L mRNA | CTD | PMID:19549813 | Taf5l1 | Rat | cyclosporin A | increases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TAF5L mRNA | CTD | PMID:25562108 | Taf5l1 | Rat | dorsomorphin | multiple interactions | ISO | TAF5L (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TAF5L mRNA | CTD | PMID:27188386 | Taf5l1 | Rat | doxorubicin | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TAF5L mRNA | CTD | PMID:29803840 | Taf5l1 | Rat | elemental selenium | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Selenium results in decreased expression of TAF5L mRNA | CTD | PMID:19244175 | Taf5l1 | Rat | epoxiconazole | decreases expression | ISO | Taf5l (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of TAF5L mRNA | CTD | PMID:35436446 | Taf5l1 | Rat | ethanol | affects expression | ISO | Taf5l (Mus musculus) | 6480464 | Ethanol affects the expression of TAF5L mRNA | CTD | PMID:30319688 | Taf5l1 | Rat | ethyl methanesulfonate | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of TAF5L mRNA | CTD | PMID:23649840 | Taf5l1 | Rat | formaldehyde | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of TAF5L mRNA | CTD | PMID:23649840 | Taf5l1 | Rat | FR900359 | increases phosphorylation | ISO | TAF5L (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of TAF5L protein | CTD | PMID:37730182 | Taf5l1 | Rat | irinotecan | multiple interactions | ISO | TAF5L (Homo sapiens) | 6480464 | [Fluorouracil co-treated with Irinotecan] results in decreased expression of TAF5L mRNA | CTD | PMID:16391804 | Taf5l1 | Rat | ketoconazole | affects expression | ISO | TAF5L (Homo sapiens) | 6480464 | Ketoconazole affects the expression of TAF5L mRNA | CTD | PMID:36621641 | Taf5l1 | Rat | lipopolysaccharide | multiple interactions | ISO | Taf5l (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in increased methylation of TAF5L gene | CTD | PMID:21212295 | Taf5l1 | Rat | methyl methanesulfonate | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of TAF5L mRNA | CTD | PMID:23649840 | Taf5l1 | Rat | nickel atom | increases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Nickel results in increased expression of TAF5L mRNA | CTD | PMID:25583101 | Taf5l1 | Rat | p-toluidine | decreases expression | EXP | | 6480464 | 4-toluidine results in decreased expression of TAF5L mRNA | CTD | PMID:27638505 | Taf5l1 | Rat | paracetamol | affects expression | ISO | Taf5l (Mus musculus) | 6480464 | Acetaminophen affects the expression of TAF5L mRNA | CTD | PMID:17562736 | Taf5l1 | Rat | phenylmercury acetate | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of TAF5L mRNA | CTD | PMID:26272509 | Taf5l1 | Rat | phenylmercury acetate | multiple interactions | ISO | TAF5L (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TAF5L mRNA | CTD | PMID:27188386 | Taf5l1 | Rat | quercetin | increases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Quercetin results in increased expression of TAF5L mRNA | CTD | PMID:21632981 | Taf5l1 | Rat | SB 431542 | multiple interactions | ISO | TAF5L (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TAF5L mRNA | CTD | PMID:27188386 | Taf5l1 | Rat | selenium atom | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Selenium results in decreased expression of TAF5L mRNA | CTD | PMID:19244175 | Taf5l1 | Rat | silicon dioxide | increases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of TAF5L mRNA | CTD | PMID:23806026 | Taf5l1 | Rat | tamoxifen | affects expression | ISO | Taf5l (Mus musculus) | 6480464 | Tamoxifen affects the expression of TAF5L mRNA | CTD | PMID:17555576 | Taf5l1 | Rat | titanium dioxide | increases expression | ISO | TAF5L (Homo sapiens) | 6480464 | titanium dioxide results in increased expression of TAF5L mRNA | CTD | PMID:34973136 | Taf5l1 | Rat | trimellitic anhydride | increases expression | ISO | Taf5l (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of TAF5L mRNA | CTD | PMID:19042947 | Taf5l1 | Rat | triptonide | increases expression | ISO | Taf5l (Mus musculus) | 6480464 | triptonide results in increased expression of TAF5L mRNA | CTD | PMID:33045310 | Taf5l1 | Rat | valproic acid | affects expression | ISO | TAF5L (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TAF5L mRNA | CTD | PMID:25979313 | Taf5l1 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of TAF5L mRNA | CTD | PMID:23555832 | Taf5l1 | Rat | vincristine | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Vincristine results in decreased expression of TAF5L mRNA | CTD | PMID:23649840 | Taf5l1 | Rat | vitamin E | decreases expression | ISO | TAF5L (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of TAF5L mRNA | CTD | PMID:19244175 | |