TAF5L (TATA-box binding protein associated factor 5 like) - Rat Genome Database

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Gene: TAF5L (TATA-box binding protein associated factor 5 like) Chlorocebus sabaeus
Analyze
Symbol: TAF5L
Name: TATA-box binding protein associated factor 5 like
RGD ID: 18574638
Description: ENCODES a protein that exhibits transcription coactivator activity (inferred); INVOLVED IN regulation of DNA-templated transcription (ortholog); regulation of somatic stem cell population maintenance (ortholog); regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH Actin-Accumulation Myopathy (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytoplasmic ribonucleoprotein granule (ortholog); nuclear speck (ortholog); SAGA complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12566,859,264 - 66,892,877 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2566,858,911 - 66,881,081 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605568,720,607 - 68,753,722 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TAF5L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12566,859,264 - 66,892,877 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2566,858,911 - 66,881,081 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605568,720,607 - 68,753,722 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TAF5L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381229,593,134 - 229,626,122 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1229,593,134 - 229,626,122 (-)EnsemblGRCh38hg38GRCh38
GRCh371229,728,881 - 229,761,869 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361227,795,481 - 227,828,417 (-)NCBINCBI36Build 36hg18NCBI36
Build 341226,035,602 - 226,068,460NCBI
Celera1202,996,790 - 203,029,673 (-)NCBICelera
Cytogenetic Map1q42.13NCBI
HuRef1200,219,088 - 200,252,013 (-)NCBIHuRef
CHM1_11231,001,159 - 231,034,105 (-)NCBICHM1_1
T2T-CHM13v2.01228,972,074 - 229,005,072 (-)NCBIT2T-CHM13v2.0
Taf5l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398124,723,049 - 124,748,136 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8124,723,057 - 124,748,136 (-)EnsemblGRCm39 Ensembl
GRCm388123,996,310 - 124,021,397 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,996,318 - 124,021,397 (-)EnsemblGRCm38mm10GRCm38
MGSCv378126,520,210 - 126,545,209 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368126,882,400 - 126,907,399 (-)NCBIMGSCv36mm8
Celera8128,276,365 - 128,290,026 (-)NCBICelera
Cytogenetic Map8E2NCBI
cM Map872.31NCBI
Taf5l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,889,153 - 68,908,480 (-)NCBIGRCr8
mRatBN7.21951,991,704 - 52,011,001 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,991,708 - 52,011,295 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1958,774,970 - 58,793,905 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01959,627,362 - 59,646,314 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01961,701,397 - 61,720,332 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01956,781,854 - 56,801,005 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,781,859 - 56,799,445 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01967,497,406 - 67,516,350 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41954,190,450 - 54,209,389 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11954,196,180 - 54,202,880 (-)NCBI
Celera1951,366,198 - 51,385,134 (-)NCBICelera
Cytogenetic Map19q12NCBI
Taf5l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554928,479,194 - 8,517,105 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554928,478,147 - 8,515,988 (+)NCBIChiLan1.0ChiLan1.0
TAF5L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2119,585,861 - 19,618,794 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1119,778,134 - 19,811,085 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01205,137,767 - 205,170,704 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11210,168,370 - 210,200,903 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1210,168,379 - 210,200,903 (-)Ensemblpanpan1.1panPan2
TAF5L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.149,646,516 - 9,674,318 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl49,646,510 - 9,673,148 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha49,637,148 - 9,665,450 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.049,676,557 - 9,704,884 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl49,676,606 - 9,703,979 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.149,680,590 - 9,708,468 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.049,794,777 - 9,823,249 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0410,046,852 - 10,075,167 (+)NCBIUU_Cfam_GSD_1.0
Taf5l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934443,955,747 - 43,976,730 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648420,127,235 - 20,143,273 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648420,123,039 - 20,143,063 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAF5L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1460,255,375 - 60,286,349 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11460,254,502 - 60,286,368 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21465,077,397 - 65,109,260 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Taf5l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477519,496,986 - 19,525,489 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477519,496,924 - 19,525,495 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 2 14
Low 34 20 46
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000008690   ⟹   ENSCSAP00000006830
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2566,858,911 - 66,881,081 (-)Ensembl
RefSeq Acc Id: XM_007989757   ⟹   XP_007987948
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12566,859,264 - 66,892,877 (-)NCBI
Vero_WHO_p1.0NW_02366605568,720,607 - 68,753,722 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007989758   ⟹   XP_007987949
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12566,859,264 - 66,891,959 (-)NCBI
Vero_WHO_p1.0NW_02366605568,720,607 - 68,753,330 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007989759   ⟹   XP_007987950
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12566,859,264 - 66,872,364 (-)NCBI
Vero_WHO_p1.0NW_02366605568,720,607 - 68,737,728 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037986023   ⟹   XP_037841951
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605568,720,607 - 68,753,253 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007987948 (Get FASTA)   NCBI Sequence Viewer  
  XP_007987949 (Get FASTA)   NCBI Sequence Viewer  
  XP_007987950 (Get FASTA)   NCBI Sequence Viewer  
  XP_037841951 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006830
  ENSCSAP00000006830.1
Reference Protein Sequences
RefSeq Acc Id: XP_007987948   ⟸   XM_007989757
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RDZ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007987949   ⟸   XM_007989758
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RDZ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007987950   ⟸   XM_007989759
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000006830   ⟸   ENSCSAT00000008690
RefSeq Acc Id: XP_037841951   ⟸   XM_037986023
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010605 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008690.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.500 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  TFIID_NTD2 UniProtKB/TrEMBL
  TFIID_NTD2_sf UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103230728 UniProtKB/TrEMBL
NCBI Gene TAF5L ENTREZGENE
PANTHER PTHR19879 UniProtKB/TrEMBL
  PTHR19879:SF6 UniProtKB/TrEMBL
Pfam TFIID_NTD2 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF160897 UniProtKB/TrEMBL
  SSF50978 UniProtKB/TrEMBL
UniProt A0A0D9RDZ1 ENTREZGENE, UniProtKB/TrEMBL