Tjp3 (tight junction protein 3) - Rat Genome Database

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Gene: Tjp3 (tight junction protein 3) Rattus norvegicus
Analyze
Symbol: Tjp3
Name: tight junction protein 3
RGD ID: 1309247
Description: Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in several processes, including establishment of endothelial intestinal barrier; positive regulation of blood-brain barrier permeability; and protein localization to cell-cell junction. Predicted to act upstream of or within regulation of G1/S transition of mitotic cell cycle. Located in cell-cell junction. Orthologous to human TJP3 (tight junction protein 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC314640; tight junction protein ZO-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,078,757 - 9,097,003 (+)NCBIGRCr8
mRatBN7.278,427,650 - 8,446,279 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,432,811 - 8,446,279 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,318,391 - 11,330,630 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,193,875 - 13,206,113 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,061,441 - 11,073,680 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,295,892 - 11,314,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,295,892 - 11,315,615 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,463,323 - 11,481,943 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,917,359 - 9,930,081 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.179,919,330 - 9,929,982 (+)NCBI
Celera76,622,067 - 6,634,606 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tjp3RatCOVID-19  ISOTJP3 (Homo sapiens)9068941mRNA:decreased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tjp3Ratamenorrhea  ISOTJP3 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary amenorrheaClinVarPMID:21681106
Tjp3RatRASopathy  ISOTJP3 (Homo sapiens)8554872ClinVar Annotator: match by term: RASopathyClinVarPMID:23379592 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tjp3Ratautism spectrum disorder  ISOTJP3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:35663546
Tjp3RatProstatic Neoplasms  ISOTJP3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17013881

1 to 20 of 111 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tjp3Rat1,2-dimethylhydrazine increases expressionISOTjp3 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of TJP3 mRNACTDPMID:22206623
Tjp3Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of TJP3 mRNACTDPMID:17557909
Tjp3Rat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of TJP3 mRNACTDPMID:29097150
Tjp3Rat17beta-estradiol multiple interactionsISOTJP3 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of TJP3 mRNACTDPMID:30165855
Tjp3Rat17beta-estradiol increases expressionISOTjp3 (Mus musculus)6480464Estradiol results in increased expression of TJP3 mRNACTDPMID:39298647
Tjp3Rat2,2',5,5'-tetrachlorobiphenyl decreases expressionEXP 64804642 more ...CTDPMID:23829299
Tjp3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOTjp3 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of TJP3 mRNACTDPMID:28922406
Tjp3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of TJP3 mRNACTDPMID:33387578
Tjp3Rat2,3,7,8-Tetrachlorodibenzofuran increases expressionEXP 64804642 more ...CTDPMID:32109520
Tjp3Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of TJP3 mRNACTDPMID:21346803
Tjp3Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of TJP3 mRNACTDPMID:21346803
Tjp3Rat2-hydroxypropanoic acid decreases expressionISOTJP3 (Homo sapiens)6480464Lactic Acid results in decreased expression of TJP3 mRNACTDPMID:30851411
Tjp3Rat3-Nitrobenzanthrone decreases expressionISOTJP3 (Homo sapiens)64804643-nitrobenzanthrone results in decreased expression of TJP3 mRNACTDPMID:34036453
Tjp3Rat4,4'-sulfonyldiphenol increases expressionISOTjp3 (Mus musculus)6480464bisphenol S results in increased expression of TJP3 mRNACTDPMID:39298647
Tjp3Rat4-hydroxyphenyl retinamide increases expressionISOTjp3 (Mus musculus)6480464Fenretinide results in increased expression of TJP3 mRNACTDPMID:28973697
Tjp3Rat5-aza-2'-deoxycytidine affects expressionISOTJP3 (Homo sapiens)6480464Decitabine affects the expression of TJP3 mRNACTDPMID:23300844
Tjp3Rat5-fluorouracil affects expressionISOTJP3 (Homo sapiens)6480464Fluorouracil affects the expression of TJP3 mRNACTDPMID:16584549
Tjp3Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of TJP3 mRNACTDPMID:24780913
Tjp3Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of TJP3 mRNACTDPMID:31881176
Tjp3Ratacrylamide decreases expressionISOTjp3 (Mus musculus)6480464Acrylamide results in decreased expression of TJP3 mRNACTDPMID:35032568

1 to 20 of 111 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tjp3Ratcell-cell adhesion involved_inIBAFB:FBgn0262614 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tjp3Ratcell-cell junction organization involved_inIBAFB:FBgn0262614 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tjp3Ratestablishment of endothelial intestinal barrier involved_inIBAPANTHER:PTN000355588 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tjp3Ratpositive regulation of blood-brain barrier permeability involved_inIBAPANTHER:PTN000355588 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tjp3Ratprotein localization to cell-cell junction involved_inIBAMGI:98759 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tjp3Ratregulation of G1/S transition of mitotic cell cycle acts_upstream_of_or_withinISOTjp3 (Mus musculus)1624291MGI:88313 PMID:21411630RGDPMID:21411630

Cellular Component
1 to 20 of 27 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tjp3Ratanchoring junction located_inIEAUniProtKB-KW:KW-09651600115GO_REF:0000043UniProtGO_REF:0000043
Tjp3Ratapical plasma membrane located_inISOTjp3 (Mus musculus)1624291 PMID:14622136RGDPMID:14622136
Tjp3Ratbicellular tight junction located_inISOTJP3 (Homo sapiens)1624291 PMID:18823282RGDPMID:18823282
Tjp3Ratbicellular tight junction located_inIEAUniProtKB-SubCell:SL-02651600115GO_REF:0000044UniProtGO_REF:0000044
Tjp3Ratbicellular tight junction located_inIEAUniProtKB:O95049 and ensembl:ENSP000004392781600115GO_REF:0000107EnsemblGO_REF:0000107
Tjp3Ratbicellular tight junction located_inIEAInterPro:IPR005417 and InterPro:IPR0054201600115GO_REF:0000002InterProGO_REF:0000002
Tjp3Ratbicellular tight junction is_active_inIBAMGI:1351650 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tjp3Ratbicellular tight junction located_inISOTjp3 (Mus musculus)1624291 PMID:14622136 and PMID:17000770RGDPMID:14622136 and PMID:17000770
Tjp3Ratbicellular tight junction located_inIEAUniProtKB-KW:KW-07961600115GO_REF:0000043UniProtGO_REF:0000043
Tjp3Ratcell junction located_inISOTJP3 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Tjp3Ratcell junction located_inIEAUniProtKB:O95049 and ensembl:ENSP000004392781600115GO_REF:0000107EnsemblGO_REF:0000107
Tjp3Ratcell surface located_inISOTJP3 (Canis lupus familiaris)1624291 PMID:12507281RGDPMID:12507281
Tjp3Ratcell-cell junction located_inIDA 14995318PMID:25486565ARUK-UCL 
Tjp3Ratcell-cell junction located_inISOTjp3 (Mus musculus)1624291 PMID:25486565RGDPMID:25486565
Tjp3Ratcytosol located_inISOTjp3 (Mus musculus)1624291 PMID:25486565RGDPMID:25486565
Tjp3Ratnucleoplasm located_inISOTJP3 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Tjp3Ratnucleoplasm located_inIEAUniProtKB:O95049 and ensembl:ENSP000004392781600115GO_REF:0000107EnsemblGO_REF:0000107
Tjp3Ratnucleus located_inISOTjp3 (Mus musculus)1624291 PMID:25486565RGDPMID:25486565
Tjp3Ratnucleus located_inISOTJP3 (Homo sapiens)1624291 PMID:18823282RGDPMID:18823282
Tjp3Ratnucleus located_inIEAUniProtKB:O95049 and ensembl:ENSP000004392781600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 27 rows

Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Qiao X, etal., Cell Cycle. 2014;13(19):3059-75. doi: 10.4161/15384101.2014.949091.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9531559   PMID:12507281   PMID:14622136   PMID:17000770   PMID:18823282   PMID:21411630   PMID:31904090  



Tjp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,078,757 - 9,097,003 (+)NCBIGRCr8
mRatBN7.278,427,650 - 8,446,279 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,432,811 - 8,446,279 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,318,391 - 11,330,630 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,193,875 - 13,206,113 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,061,441 - 11,073,680 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,295,892 - 11,314,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,295,892 - 11,315,615 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,463,323 - 11,481,943 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,917,359 - 9,930,081 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.179,919,330 - 9,929,982 (+)NCBI
Celera76,622,067 - 6,634,606 (+)NCBICelera
Cytogenetic Map7q11NCBI
TJP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,708,384 - 3,750,813 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl193,708,362 - 3,750,813 (+)EnsemblGRCh38hg38GRCh38
GRCh37193,708,382 - 3,750,811 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,679,374 - 3,701,682 (+)NCBINCBI36Build 36hg18NCBI36
Build 34193,679,373 - 3,701,682NCBI
Celera193,665,215 - 3,688,325 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef193,472,758 - 3,515,524 (+)NCBIHuRef
CHM1_1193,707,932 - 3,750,434 (+)NCBICHM1_1
T2T-CHM13v2.0193,686,785 - 3,730,065 (+)NCBIT2T-CHM13v2.0
Tjp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,109,022 - 81,127,415 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1081,109,041 - 81,127,415 (-)EnsemblGRCm39 Ensembl
GRCm381081,273,188 - 81,291,581 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,273,207 - 81,291,581 (-)EnsemblGRCm38mm10GRCm38
MGSCv371080,735,945 - 80,754,012 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361080,676,357 - 80,694,363 (-)NCBIMGSCv36mm8
Celera1082,293,548 - 82,311,616 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Tjp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,630,066 - 5,647,090 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554955,620,817 - 5,647,211 (+)NCBIChiLan1.0ChiLan1.0
TJP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,116,926 - 8,146,520 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,350,104 - 7,378,066 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0192,733,016 - 2,774,469 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,682,654 - 3,722,833 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,682,654 - 3,722,833 (+)Ensemblpanpan1.1panPan2
TJP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,720,632 - 55,746,776 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,720,632 - 55,746,965 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,446,074 - 55,472,220 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02056,380,809 - 56,406,987 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2056,380,813 - 56,407,663 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,436,631 - 55,456,519 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,918,643 - 55,946,032 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02056,117,393 - 56,144,800 (-)NCBIUU_Cfam_GSD_1.0
Tjp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,710,579 - 215,732,701 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,100,712 - 2,124,107 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,112,352 - 2,124,204 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TJP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,938,152 - 74,971,531 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,938,153 - 74,971,431 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,529,624 - 75,562,870 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TJP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,474,639 - 3,505,801 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl63,481,060 - 3,505,678 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660814,744,153 - 4,790,349 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tjp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248286,383,767 - 6,398,359 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248286,374,678 - 6,398,483 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Tjp3
53 total Variants

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:33
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000027847
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 14 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat

1 to 10 of 14 rows
RH128401  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr879,096,994 - 9,097,275 (+)Marker Load Pipeline
mRatBN7.278,446,270 - 8,446,551 (+)MAPPERmRatBN7.2
Rnor_6.0711,314,527 - 11,314,807NCBIRnor6.0
Rnor_5.0711,481,935 - 11,482,215UniSTSRnor5.0
RGSC_v3.479,930,073 - 9,930,353UniSTSRGSC3.4
Celera76,634,598 - 6,634,878UniSTS
Cytogenetic Map7q11UniSTS
RH131893  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,446,080 - 8,446,231 (+)MAPPERmRatBN7.2
Rnor_6.0711,314,337 - 11,314,487NCBIRnor6.0
Rnor_5.0711,481,745 - 11,481,895UniSTSRnor5.0
RGSC_v3.479,929,883 - 9,930,033UniSTSRGSC3.4
Celera76,634,408 - 6,634,558UniSTS
Cytogenetic Map7q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000027847   ⟹   ENSRNOP00000027847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,435,618 - 8,446,279 (+)Ensembl
Rnor_6.0 Ensembl711,301,957 - 11,314,535 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089004   ⟹   ENSRNOP00000074662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,432,811 - 8,446,279 (+)Ensembl
Rnor_6.0 Ensembl711,295,892 - 11,315,615 (+)Ensembl
RefSeq Acc Id: NM_001108073   ⟹   NP_001101543
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,084,424 - 9,097,003 (+)NCBI
mRatBN7.278,433,698 - 8,446,279 (+)NCBI
Rnor_6.0711,301,957 - 11,314,535 (+)NCBI
Rnor_5.0711,463,323 - 11,481,943 (+)NCBI
RGSC_v3.479,917,359 - 9,930,081 (+)RGD
Celera76,622,067 - 6,634,606 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240933   ⟹   XP_006240995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,078,757 - 9,096,988 (+)NCBI
mRatBN7.278,427,650 - 8,446,266 (+)NCBI
Rnor_6.0711,295,892 - 11,314,522 (+)NCBI
Rnor_5.0711,463,323 - 11,481,943 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079017   ⟹   XP_038934945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,084,385 - 9,096,988 (+)NCBI
mRatBN7.278,433,664 - 8,446,266 (+)NCBI
Protein RefSeqs NP_001101543 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240995 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934945 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL89168 (Get FASTA)   NCBI Sequence Viewer  
  EDL89169 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027847
  ENSRNOP00000027847.5
  ENSRNOP00000074662.2
RefSeq Acc Id: NP_001101543   ⟸   NM_001108073
- UniProtKB: D3Z8G7 (UniProtKB/TrEMBL),   A6K898 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240995   ⟸   XM_006240933
- Peptide Label: isoform X2
- UniProtKB: A6K899 (UniProtKB/TrEMBL),   D3Z8G7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074662   ⟸   ENSRNOT00000089004
Ensembl Acc Id: ENSRNOP00000027847   ⟸   ENSRNOT00000027847
RefSeq Acc Id: XP_038934945   ⟸   XM_039079017
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K8M3 (UniProtKB/TrEMBL),   D3Z8G7 (UniProtKB/TrEMBL)
Guanylate kinase-like   PDZ   SH3

Name Modeler Protein Id AA Range Protein Structure
AF-D3Z8G7-F1-model_v2 AlphaFold D3Z8G7 1-907 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694978
Promoter ID:EPDNEW_R5503
Type:initiation region
Name:Tjp3_1
Description:tight junction protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0711,296,193 - 11,296,253EPDNEW


1 to 38 of 38 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-35012 BioCyc
Ensembl Genes ENSRNOG00000020501 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027847 ENTREZGENE
  ENSRNOT00000027847.6 UniProtKB/TrEMBL
  ENSRNOT00000089004.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro Guanylate_kin UniProtKB/TrEMBL
  Guanylate_kin/L-typ_Ca_channel UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  PDZ/DHR/GLGF UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  ZonOcculdens UniProtKB/TrEMBL
  ZonOcculS3 UniProtKB/TrEMBL
KEGG Report rno:314640 UniProtKB/TrEMBL
NCBI Gene 314640 ENTREZGENE
PANTHER PTHR13865:SF11 UniProtKB/TrEMBL
  TIGHT JUNCTION PROTEIN UniProtKB/TrEMBL
Pfam Guanylate_kin UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PhenoGen Tjp3 PhenoGen
PRINTS ZONOCCLUDNS UniProtKB/TrEMBL
  ZONOCCLUDNS3 UniProtKB/TrEMBL
PROSITE GUANYLATE_KINASE_2 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020501 RatGTEx
SMART GuKc UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP PDZ UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2K8M3 ENTREZGENE, UniProtKB/TrEMBL
  A6K898 ENTREZGENE, UniProtKB/TrEMBL
  A6K899 ENTREZGENE, UniProtKB/TrEMBL
  D3Z8G7 ENTREZGENE, UniProtKB/TrEMBL
1 to 38 of 38 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Tjp3  tight junction protein 3   Tjp3_predicted  tight junction protein 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tjp3_predicted  tight junction protein 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED