Ythdf1 (YTH N6-methyladenosine RNA binding protein F1) - Rat Genome Database

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Gene: Ythdf1 (YTH N6-methyladenosine RNA binding protein F1) Rattus norvegicus
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Symbol: Ythdf1
Name: YTH N6-methyladenosine RNA binding protein F1
RGD ID: 1308932
Description: Predicted to enable N6-methyladenosine-containing RNA reader activity; mRNA binding activity; and ribosome binding activity. Predicted to be involved in several processes, including learning or memory; post-transcriptional regulation of gene expression; and stress granule assembly. Predicted to be located in P-body and cytoplasmic stress granule. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human YTHDF1 (YTH N6-methyladenosine RNA binding protein F1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC296467; YTH domain family 1; YTH domain family protein 1; YTH domain family, member 1; YTH domain-containing family protein 1; YTH N(6)-methyladenosine RNA binding protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83188,402,228 - 188,417,740 (-)NCBIGRCr8
mRatBN7.23168,024,660 - 168,040,172 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,024,663 - 168,040,172 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3172,404,856 - 172,420,353 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03181,363,946 - 181,379,443 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,025,619 - 178,041,133 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03176,415,911 - 176,431,423 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3176,415,914 - 176,431,423 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03180,125,831 - 180,141,407 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,014,277 - 170,029,789 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13169,920,315 - 169,935,825 (-)NCBI
Celera3164,544,900 - 164,560,398 (+)NCBICelera
Cytogenetic Map3q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
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Original Reference(s)
Ythdf1Ratcolorectal cancer amelioratesISOYTHDF1 (Homo sapiens)153344629human cells in mouse modelRGD 
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Original Reference(s)
Ythdf1Ratautosomal dominant nocturnal frontal lobe epilepsy  ISOYTHDF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal dominant nocturnal frontal lobe epilepsyClinVarPMID:28492532
Ythdf1Ratbenign familial infantile seizures 6  ISOYTHDF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal dominant nocturnal frontal lobe epilepsyClinVarPMID:28492532
Ythdf1Ratdevelopmental and epileptic encephalopathy  ISOYTHDF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathyClinVarPMID:24811917 more ...
Ythdf1Ratdevelopmental and epileptic encephalopathy 33  ISOYTHDF1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:24811917 more ...
Ythdf1Ratearly infantile epileptic encephalopathy  ISOYTHDF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Early infantile epileptic encephalopathyClinVarPMID:24811917 more ...
Ythdf1Ratneuronal ceroid lipofuscinosis  ISOYTHDF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Ceroid storage diseaseClinVarPMID:25921748 more ...
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Ythdf1Ratmultiple myeloma  ISOYTHDF1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:35038059

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Original Reference(s)
Ythdf1Rat(-)-epigallocatechin 3-gallate multiple interactionsISOYTHDF1 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of YTHDF1 mRNACTDPMID:22079256
Ythdf1Rat1,2-dichloroethane decreases expressionISOYthdf1 (Mus musculus)6480464ethylene dichloride results in decreased expression of YTHDF1 mRNACTDPMID:28960355
Ythdf1Rat1,2-dimethylhydrazine multiple interactionsISOYthdf1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of YTHDF1 mRNACTDPMID:22206623
Ythdf1Rat1,4-benzoquinone increases expressionISOYthdf1 (Mus musculus)6480464quinone results in increased expression of YTHDF1 mRNACTDPMID:36306860
Ythdf1Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expressionISOYTHDF1 (Homo sapiens)6480464Metribolone results in increased expression of YTHDF1 mRNACTDPMID:17010196
Ythdf1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOYthdf1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of YTHDF1 mRNACTDPMID:21570461
Ythdf1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of YTHDF1 mRNACTDPMID:33387578
Ythdf1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOYTHDF1 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of YTHDF1 mRNACTDPMID:22574217
Ythdf1Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of YTHDF1 mRNACTDPMID:21346803
Ythdf1Rat4,4'-sulfonyldiphenol increases expressionISOYthdf1 (Mus musculus)6480464bisphenol S results in increased expression of YTHDF1 mRNACTDPMID:39298647
Ythdf1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of YTHDF1 mRNACTDPMID:30047161
Ythdf1Ratactinomycin D multiple interactionsISOYTHDF1 (Homo sapiens)6480464YTHDF1 protein affects the reaction [Dactinomycin results in decreased stability of AKT1 mRNA] more ...CTDPMID:37061066
Ythdf1Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of YTHDF1 mRNACTDPMID:30047161
Ythdf1Rataristolochic acid A increases expressionISOYTHDF1 (Homo sapiens)6480464aristolochic acid I results in increased expression of YTHDF1 mRNACTDPMID:33212167
Ythdf1Ratarsane increases expressionISOYTHDF1 (Homo sapiens)6480464Arsenic results in increased expression of YTHDF1CTDPMID:35363433
Ythdf1Ratarsenic atom increases expressionISOYTHDF1 (Homo sapiens)6480464Arsenic results in increased expression of YTHDF1CTDPMID:35363433
Ythdf1Ratatrazine decreases expressionISOYTHDF1 (Homo sapiens)6480464Atrazine results in decreased expression of YTHDF1 mRNACTDPMID:22378314
Ythdf1Ratbenzo[a]pyrene increases methylationISOYTHDF1 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of YTHDF1 promoterCTDPMID:27901495
Ythdf1Ratbis(2-ethylhexyl) phthalate multiple interactionsISOYTHDF1 (Homo sapiens)6480464[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in decreased methylation of YTHDF1 promoterCTDPMID:33872906
Ythdf1Ratbis(2-ethylhexyl) phthalate increases expressionISOYthdf1 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of YTHDF1 mRNACTDPMID:34319233 and PMID:36423848

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Biological Process
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Original Reference(s)
Ythdf1Ratlearning involved_inISOYthdf1 (Mus musculus)1624291 PMID:30401835RGDPMID:30401835
Ythdf1Ratlearning involved_inIEAUniProtKB:P59326 and ensembl:ENSMUSP000000378081600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1Ratmemory involved_inISOYthdf1 (Mus musculus)1624291 PMID:30401835RGDPMID:30401835
Ythdf1Ratmemory involved_inIEAUniProtKB:P59326 and ensembl:ENSMUSP000000378081600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1RatmRNA destabilization involved_inISOYTHDF1 (Homo sapiens)1624291 PMID:32492408RGDPMID:32492408
Ythdf1RatmRNA destabilization involved_inIEAUniProtKB:Q9BYJ9 and ensembl:ENSP000003593641600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1RatmRNA destabilization involved_inIEAUniProtKB:P59326 and ensembl:ENSMUSP000000378081600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1RatmRNA destabilization involved_inIBAMGI:1917431 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ythdf1RatmRNA destabilization involved_inISOYthdf1 (Mus musculus)1624291 PMID:32943573RGDPMID:32943573
Ythdf1Ratorganelle assembly involved_inISOYTHDF1 (Homo sapiens)1624291 PMID:31292544RGDPMID:31292544
Ythdf1Ratorganelle assembly involved_inIEAUniProtKB:Q9BYJ9 and ensembl:ENSP000003593641600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1Ratpositive regulation of translation involved_inISOYTHDF1 (Homo sapiens)1624291 PMID:28106072 and PMID:28106076RGDPMID:28106072 and PMID:28106076
Ythdf1Ratpositive regulation of translation involved_inIEAUniProtKB:P59326 and ensembl:ENSMUSP000000378081600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1Ratpositive regulation of translation involved_inIEAUniProtKB:Q9BYJ9 and ensembl:ENSP000003593641600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1Ratpositive regulation of translation involved_inISOYthdf1 (Mus musculus)1624291 PMID:30401835 more ...RGDPMID:30401835 more ...
Ythdf1Ratpositive regulation of translational initiation NOT|involved_inISOYTHDF1 (Homo sapiens)1624291 PMID:32492408RGDPMID:32492408
Ythdf1Ratpositive regulation of translational initiation NOT|involved_inISOYthdf1 (Mus musculus)1624291 PMID:32943573RGDPMID:32943573
Ythdf1Ratpositive regulation of translational initiation involved_inISOYTHDF1 (Homo sapiens)1624291 PMID:26046440RGDPMID:26046440
Ythdf1Ratregulation of antigen processing and presentation involved_inISOYthdf1 (Mus musculus)1624291 PMID:30728504RGDPMID:30728504
Ythdf1Ratregulation of antigen processing and presentation involved_inIEAUniProtKB:P59326 and ensembl:ENSMUSP000000378081600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
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Original Reference(s)
Ythdf1Ratcytoplasm is_active_inIBAFB:FBgn0039261 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ythdf1Ratcytoplasm located_inIEAUniProtKB:P59326 and ensembl:ENSMUSP000000378081600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1Ratcytoplasm located_inIEAUniProtKB:Q9BYJ9 and ensembl:ENSP000003593641600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1Ratcytoplasm located_inISOYthdf1 (Mus musculus)1624291 PMID:32943573RGDPMID:32943573
Ythdf1Ratcytoplasm located_inISOYTHDF1 (Homo sapiens)1624291 PMID:32492408RGDPMID:32492408
Ythdf1Ratcytoplasmic stress granule located_inISOYTHDF1 (Homo sapiens)1624291 PMID:32451507RGDPMID:32451507
Ythdf1Ratcytoplasmic stress granule located_inIEAUniProtKB:Q9BYJ9 and ensembl:ENSP000003593641600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1RatP-body located_inISOYTHDF1 (Homo sapiens)1624291 PMID:32492408RGDPMID:32492408
Ythdf1RatP-body located_inIEAUniProtKB:Q9BYJ9 and ensembl:ENSP000003593641600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
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Original Reference(s)
Ythdf1RatmRNA binding enablesIBAFB:FBgn0027616 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ythdf1RatN6-methyladenosine-containing RNA reader activity enablesIBAFB:FBgn0039261 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ythdf1RatN6-methyladenosine-containing RNA reader activity enablesIEAUniProtKB:Q9BYJ9 and ensembl:ENSP000003593641600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1RatN6-methyladenosine-containing RNA reader activity enablesISOYthdf1 (Mus musculus)1624291 PMID:30401835 more ...RGDPMID:30401835 more ...
Ythdf1RatN6-methyladenosine-containing RNA reader activity enablesIEAUniRule:UR0016957621600115GO_REF:0000104UniProtGO_REF:0000104
Ythdf1RatN6-methyladenosine-containing RNA reader activity enablesIEAUniProtKB:P59326 and ensembl:ENSMUSP000000378081600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1RatN6-methyladenosine-containing RNA reader activity enablesISOYTHDF1 (Homo sapiens)1624291 PMID:24284625 more ...RGDPMID:24284625 more ...
Ythdf1Ratprotein binding enablesISOYTHDF1 (Homo sapiens)1624291UniProtKB:A5D8V6 more ...RGDPMID:28106072 more ...
Ythdf1Ratribosome binding enablesISOYTHDF1 (Homo sapiens)1624291 PMID:26046440RGDPMID:26046440
Ythdf1Ratribosome binding enablesIEAUniProtKB:Q9BYJ9 and ensembl:ENSP000003593641600115GO_REF:0000107EnsemblGO_REF:0000107
Ythdf1RatRNA binding enablesIEAInterPro:IPR0072751600115GO_REF:0000002InterProGO_REF:0000002
Ythdf1RatRNA binding enablesIEAUniProtKB-KW:KW-06941600115GO_REF:0000043UniProtGO_REF:0000043
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Circular RNA protein tyrosine kinase 2 (circPTK2) promotes colorectal cancer proliferation, migration, invasion and chemoresistance. Jiang Z, etal., Bioengineered. 2022 Jan;13(1):810-823. doi: 10.1080/21655979.2021.2012952.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:22658674   PMID:22681889   PMID:24284625   PMID:26046440   PMID:26318451   PMID:28106072   PMID:28106076   PMID:30401835   PMID:30728504   PMID:30843071   PMID:34015275  
PMID:34310344   PMID:36894806   PMID:37572160  



Ythdf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83188,402,228 - 188,417,740 (-)NCBIGRCr8
mRatBN7.23168,024,660 - 168,040,172 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,024,663 - 168,040,172 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3172,404,856 - 172,420,353 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03181,363,946 - 181,379,443 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,025,619 - 178,041,133 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03176,415,911 - 176,431,423 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3176,415,914 - 176,431,423 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03180,125,831 - 180,141,407 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,014,277 - 170,029,789 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13169,920,315 - 169,935,825 (-)NCBI
Celera3164,544,900 - 164,560,398 (+)NCBICelera
Cytogenetic Map3q43NCBI
YTHDF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382063,195,429 - 63,216,131 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2063,195,429 - 63,216,139 (-)EnsemblGRCh38hg38GRCh38
GRCh372061,826,781 - 61,847,483 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362061,297,226 - 61,317,983 (-)NCBINCBI36Build 36hg18NCBI36
Build 342061,297,228 - 61,317,983NCBI
Celera2058,504,268 - 58,525,021 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2058,551,559 - 58,578,606 (-)NCBIHuRef
CHM1_12061,727,941 - 61,748,702 (-)NCBICHM1_1
T2T-CHM13v2.02065,000,752 - 65,021,443 (-)NCBIT2T-CHM13v2.0
Ythdf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392180,546,170 - 180,562,729 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2180,546,170 - 180,562,742 (-)EnsemblGRCm39 Ensembl
GRCm382180,904,377 - 180,920,936 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2180,904,377 - 180,920,949 (-)EnsemblGRCm38mm10GRCm38
MGSCv372180,639,082 - 180,655,641 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362180,833,785 - 180,850,344 (-)NCBIMGSCv36mm8
Celera2184,990,626 - 185,007,152 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2103.5NCBI
Ythdf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955528935,182 - 951,722 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955528935,182 - 951,722 (+)NCBIChiLan1.0ChiLan1.0
YTHDF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22168,978,501 - 68,999,192 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12068,970,507 - 68,991,196 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02059,575,703 - 59,596,447 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12061,115,366 - 61,135,639 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2061,116,645 - 61,135,769 (-)Ensemblpanpan1.1panPan2
YTHDF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12446,927,218 - 46,940,015 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2446,927,848 - 46,951,949 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2446,111,317 - 46,124,326 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02447,881,084 - 47,894,120 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2447,799,759 - 47,894,081 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12446,896,564 - 46,909,548 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02447,020,531 - 47,033,541 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,776,866 - 47,789,883 (-)NCBIUU_Cfam_GSD_1.0
Ythdf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,134,237 - 195,149,728 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651410,587,222 - 10,603,478 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651410,587,877 - 10,603,373 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YTHDF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,329,302 - 62,341,413 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11762,329,302 - 62,341,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
YTHDF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12985,373 - 1,010,533 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2985,425 - 1,012,091 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605048,723,072 - 48,745,291 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ythdf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474128,917,942 - 28,933,599 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474128,918,466 - 28,933,593 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ythdf1
30 total Variants

Predicted Target Of
Summary Value
Count of predictions:644
Count of miRNA genes:267
Interacting mature miRNAs:342
Transcripts:ENSRNOT00000037271
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 16 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3161192952169034231Rat

1 to 10 of 16 rows
D3Rat1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,026,691 - 168,026,850 (+)MAPPERmRatBN7.2
Rnor_6.03176,417,943 - 176,418,101NCBIRnor6.0
Rnor_5.03180,127,863 - 180,128,021UniSTSRnor5.0
RGSC_v3.43170,016,309 - 170,016,467UniSTSRGSC3.4
RGSC_v3.43170,016,252 - 170,016,653RGDRGSC3.4
RGSC_v3.13169,922,345 - 169,922,503RGD
Celera3164,558,222 - 164,558,366UniSTS
RH 3.4 Map31533.2RGD
RH 3.4 Map31533.2UniSTS
RH 2.0 Map31027.1RGD
SHRSP x BN Map391.5299RGD
FHH x ACI Map3104.89RGD
Cytogenetic Map3q43UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000037271   ⟹   ENSRNOP00000037700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,024,663 - 168,040,172 (-)Ensembl
Rnor_6.0 Ensembl3176,415,914 - 176,431,423 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098734   ⟹   ENSRNOP00000078758
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,024,663 - 168,039,862 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111765   ⟹   ENSRNOP00000093829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,024,663 - 168,039,878 (-)Ensembl
RefSeq Acc Id: NM_001024756   ⟹   NP_001019927
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,402,228 - 188,417,740 (-)NCBI
mRatBN7.23168,024,660 - 168,040,172 (-)NCBI
Rnor_6.03176,415,911 - 176,431,423 (-)NCBI
Rnor_5.03180,125,831 - 180,141,407 (-)NCBI
RGSC_v3.43170,014,277 - 170,029,789 (-)RGD
Celera3164,544,900 - 164,560,398 (+)RGD
Sequence:
Protein RefSeqs NP_001019927 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH97360 (Get FASTA)   NCBI Sequence Viewer  
  EDL88782 (Get FASTA)   NCBI Sequence Viewer  
  EDL88783 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000037700.5
  ENSRNOP00000078758.1
  ENSRNOP00000093829
  ENSRNOP00000093829.1
RefSeq Acc Id: NP_001019927   ⟸   NM_001024756
- UniProtKB: Q4V8J6 (UniProtKB/TrEMBL),   A0A8I6AL56 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000037700   ⟸   ENSRNOT00000037271
Ensembl Acc Id: ENSRNOP00000093829   ⟸   ENSRNOT00000111765
Ensembl Acc Id: ENSRNOP00000078758   ⟸   ENSRNOT00000098734
YTH

Name Modeler Protein Id AA Range Protein Structure
AF-Q4V8J6-F1-model_v2 AlphaFold Q4V8J6 1-559 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13692742
Promoter ID:EPDNEW_R3267
Type:initiation region
Name:Ythdf1_1
Description:YTH N-methyladenosine RNA binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03176,431,505 - 176,431,565EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-46313 BioCyc
Ensembl Genes ENSRNOG00000027015 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037271.5 UniProtKB/TrEMBL
  ENSRNOT00000098734.1 UniProtKB/TrEMBL
  ENSRNOT00000111765 ENTREZGENE
  ENSRNOT00000111765.1 UniProtKB/TrEMBL
Gene3D-CATH ph1033 like domains UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7442371 IMAGE-MGC_LOAD
InterPro YTH_domain UniProtKB/TrEMBL
  YTH_prot UniProtKB/TrEMBL
KEGG Report rno:296467 UniProtKB/TrEMBL
MGC_CLONE MGC:114393 IMAGE-MGC_LOAD
NCBI Gene 296467 ENTREZGENE
PANTHER PTHR12357 UniProtKB/TrEMBL
  YTH DOMAIN-CONTAINING FAMILY PROTEIN 1 UniProtKB/TrEMBL
Pfam YTH UniProtKB/TrEMBL
PhenoGen Ythdf1 PhenoGen
PROSITE YTH UniProtKB/TrEMBL
RatGTEx ENSRNOG00000027015 RatGTEx
UniProt A0A8I5ZLF0_RAT UniProtKB/TrEMBL
  A0A8I6AL56 ENTREZGENE, UniProtKB/TrEMBL
  A6KM74_RAT UniProtKB/TrEMBL
  F7F2Q6_RAT UniProtKB/TrEMBL
  Q4V8J6 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-03-09 Ythdf1  YTH N6-methyladenosine RNA binding protein F1  Ythdf1  YTH N(6)-methyladenosine RNA binding protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-12-01 Ythdf1  YTH N(6)-methyladenosine RNA binding protein 1  Ythdf1  YTH domain family, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Ythdf1  YTH domain family, member 1  Ythdf1  YTH domain family 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ythdf1  YTH domain family 1  Ythdf1_predicted  YTH domain family 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ythdf1_predicted  YTH domain family 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED