Cdk14 (cyclin-dependent kinase 14) - Rat Genome Database

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Gene: Cdk14 (cyclin-dependent kinase 14) Rattus norvegicus
Analyze
Symbol: Cdk14
Name: cyclin-dependent kinase 14
RGD ID: 1305544
Description: Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in G2/M transition of mitotic cell cycle; regulation of canonical Wnt signaling pathway; and regulation of cell cycle phase transition. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of cytoplasmic cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytosol and nucleus. Orthologous to human CDK14 (cyclin dependent kinase 14); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cell division protein kinase 14; LOC362316; PFTAIRE protein kinase 1; Pftk1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8429,619,237 - 30,213,651 (+)NCBIGRCr8
mRatBN7.2428,666,416 - 29,258,865 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl428,666,843 - 29,258,861 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx433,637,510 - 34,219,606 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0429,563,603 - 30,145,717 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0427,961,326 - 28,553,751 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0425,825,567 - 26,419,443 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl425,825,567 - 26,419,127 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0425,732,184 - 26,326,437 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4425,352,280 - 25,942,686 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1425,442,897 - 25,950,147 (+)NCBI
Celera424,108,211 - 24,692,789 (+)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk14Ratpleomorphic xanthoastrocytoma  ISOCDK14 (Homo sapiens)8554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk14Rathepatocellular carcinoma  ISOCDK14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22922871

1 to 20 of 107 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk14Rat1,2-dichloroethane affects expressionISOCdk14 (Mus musculus)6480464ethylene dichloride affects the expression of CDK14 mRNACTDPMID:28960355
Cdk14Rat1,3-dinitrobenzene decreases expressionEXP 64804643-dinitrobenzene results in decreased expression of CDK14 mRNACTDPMID:21983209
Cdk14Rat17alpha-ethynylestradiol increases expressionISOCdk14 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of CDK14 mRNACTDPMID:17942748
Cdk14Rat17alpha-ethynylestradiol multiple interactionsISOCdk14 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDK14 mRNACTDPMID:17942748
Cdk14Rat17beta-estradiol multiple interactionsISOCDK14 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of CDK14 mRNACTDPMID:30165855
Cdk14Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCdk14 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDK14 mRNACTDPMID:17942748
Cdk14Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of CDK14 mRNACTDPMID:32109520 and PMID:33387578
Cdk14Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCdk14 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CDK14 mRNACTDPMID:24680724
Cdk14Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Cdk14Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOCdk14 (Mus musculus)64804642 more ...CTDPMID:38648751
Cdk14Rat3,4-methylenedioxymethamphetamine increases expressionISOCdk14 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of CDK14 mRNACTDPMID:20188158
Cdk14Rat3,4-methylenedioxymethamphetamine decreases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of CDK14 mRNACTDPMID:30071829
Cdk14Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOCDK14 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of CDK14 mRNACTDPMID:28628672
Cdk14Rat3-Nitrobenzanthrone decreases expressionISOCDK14 (Homo sapiens)64804643-nitrobenzanthrone results in decreased expression of CDK14 mRNACTDPMID:34036453
Cdk14Rat4,4'-sulfonyldiphenol multiple interactionsISOCDK14 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of CDK14 mRNACTDPMID:28628672
Cdk14Rat4,4'-sulfonyldiphenol affects methylationISOCdk14 (Mus musculus)6480464bisphenol S affects the methylation of CDK14 geneCTDPMID:31683443
Cdk14Rat4-hydroxyphenyl retinamide decreases expressionISOCdk14 (Mus musculus)6480464Fenretinide results in decreased expression of CDK14 mRNACTDPMID:28973697
Cdk14Rat4-nitrophenol increases expressionISOCdk14 (Mus musculus)64804644-nitrophenol results in increased expression of CDK14 mRNACTDPMID:34673133
Cdk14Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of CDK14 mRNACTDPMID:22504374
Cdk14Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of CDK14 mRNACTDPMID:28959563

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Biological Process

  
Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk14Ratcell division involved_inIEAUniProtKB-KW:KW-01321600115GO_REF:0000043UniProtGO_REF:0000043
Cdk14RatG2/M transition of mitotic cell cycle involved_inISOCDK14 (Homo sapiens)1624291 PMID:20059949RGDPMID:20059949
Cdk14RatG2/M transition of mitotic cell cycle involved_inIEAUniProtKB:O94921 and ensembl:ENSP000003693901600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratregulation of canonical Wnt signaling pathway involved_inISOCDK14 (Homo sapiens)1624291 PMID:20059949RGDPMID:20059949
Cdk14Ratregulation of canonical Wnt signaling pathway involved_inIEAUniProtKB:O94921 and ensembl:ENSP000003693901600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratregulation of cell cycle phase transition involved_inIBAPANTHER:PTN002373304 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdk14RatWnt signaling pathway involved_inIEAUniProtKB-KW:KW-08791600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component
1 to 20 of 23 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk14Ratcyclin-dependent protein kinase holoenzyme complex part_ofISOCDK14 (Homo sapiens)1624291 PMID:19524571RGDPMID:19524571
Cdk14Ratcyclin-dependent protein kinase holoenzyme complex part_ofISOCdk14 (Mus musculus)1624291 PMID:19524571RGDPMID:19524571
Cdk14Ratcyclin-dependent protein kinase holoenzyme complex part_ofIEAUniProtKB:O35495 and ensembl:ENSMUSP000000307631600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratcyclin-dependent protein kinase holoenzyme complex part_ofIEAUniProtKB:O94921 and ensembl:ENSP000003693901600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratcytoplasm is_active_inIBAMGI:101765 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdk14Ratcytoplasm located_inIEAUniProtKB:O35495 and ensembl:ENSMUSP000000307631600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratcytoplasm located_inISOCdk14 (Mus musculus)1624291 PMID:9202329RGDPMID:9202329
Cdk14Ratcytoplasmic cyclin-dependent protein kinase holoenzyme complex part_ofISOCDK14 (Homo sapiens)1624291 PMID:19524571 and PMID:20059949RGDPMID:19524571 and PMID:20059949
Cdk14Ratcytoplasmic cyclin-dependent protein kinase holoenzyme complex part_ofIEAUniProtKB:O94921 and ensembl:ENSP000003693901600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratcytosol located_inISOCDK14 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Cdk14Ratcytosol located_inIEAUniProtKB:O35495 and ensembl:ENSMUSP000000307631600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratcytosol located_inISOCdk14 (Mus musculus)1624291 PMID:9202329RGDPMID:9202329
Cdk14Ratcytosol is_active_inIBAMGI:894318 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdk14Ratcytosol located_inIEAUniProtKB:O94921 and ensembl:ENSP000003693901600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratnucleoplasm located_inIEAUniProtKB:O94921 and ensembl:ENSP000003693901600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratnucleoplasm located_inISOCDK14 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Cdk14Ratnucleus located_inISOCdk14 (Mus musculus)1624291 PMID:9202329RGDPMID:9202329
Cdk14Ratnucleus located_inIEAUniProtKB:O35495 and ensembl:ENSMUSP000000307631600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratnucleus is_active_inIBAFB:FBgn0015618 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdk14Ratplasma membrane located_inIEAUniProtKB:O94921 and ensembl:ENSP000003693901600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 23 rows

Molecular Function
1 to 18 of 18 rows

  
Object Symbol
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Term
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Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk14RatATP binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
Cdk14RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Cdk14RatATP binding enablesIEAInterPro:IPR000719 and InterPro:IPR0174411600115GO_REF:0000002InterProGO_REF:0000002
Cdk14Ratcyclin binding enablesISOCDK14 (Homo sapiens)1624291UniProtKB:Q8ND76 more ...RGDPMID:19524571 and PMID:20059949
Cdk14Ratcyclin binding enablesIEAUniProtKB:O94921 and ensembl:ENSP000003693901600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratcyclin binding enablesIBAPANTHER:PTN001172735 and UniProtKB:O949211600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdk14Ratcyclin-dependent protein serine/threonine kinase activity enablesISOCDK14 (Homo sapiens)1624291 PMID:19524571 and PMID:20059949RGDPMID:19524571 and PMID:20059949
Cdk14Ratcyclin-dependent protein serine/threonine kinase activity enablesIEAUniProtKB:O94921 and ensembl:ENSP000003693901600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratcyclin-dependent protein serine/threonine kinase activity enablesIBACGD:CAL0000200290 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdk14Ratkinase activity enablesIEAUniProtKB-KW:KW-04181600115GO_REF:0000043UniProtGO_REF:0000043
Cdk14Ratnucleotide binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
Cdk14Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Cdk14Ratprotein binding enablesISOCDK14 (Homo sapiens)1624291UniProtKB:P08238 more ...RGDPMID:16775625 more ...
Cdk14Ratprotein kinase activity enablesIEAUniProtKB:O35495 and ensembl:ENSMUSP000000307631600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk14Ratprotein kinase activity enablesISOCdk14 (Mus musculus)1624291 PMID:9202329RGDPMID:9202329
Cdk14Ratprotein kinase activity enablesIEAInterPro:IPR000719 and InterPro:IPR0082711600115GO_REF:0000002InterProGO_REF:0000002
Cdk14Ratprotein serine/threonine kinase activity enablesIEAUniProtKB-KW:KW-07231600115GO_REF:0000043UniProtGO_REF:0000043
Cdk14Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
1 to 18 of 18 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9202329   PMID:12477932   PMID:19524571   PMID:20059949   PMID:25355490   PMID:38575601  



Cdk14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8429,619,237 - 30,213,651 (+)NCBIGRCr8
mRatBN7.2428,666,416 - 29,258,865 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl428,666,843 - 29,258,861 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx433,637,510 - 34,219,606 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0429,563,603 - 30,145,717 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0427,961,326 - 28,553,751 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0425,825,567 - 26,419,443 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl425,825,567 - 26,419,127 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0425,732,184 - 26,326,437 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4425,352,280 - 25,942,686 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1425,442,897 - 25,950,147 (+)NCBI
Celera424,108,211 - 24,692,789 (+)NCBICelera
Cytogenetic Map4q13NCBI
CDK14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38790,596,321 - 91,210,590 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl790,466,424 - 91,210,590 (+)EnsemblGRCh38hg38GRCh38
GRCh37790,225,635 - 90,839,905 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36790,176,648 - 90,677,840 (+)NCBINCBI36Build 36hg18NCBI36
Build 34789,983,362 - 90,484,555NCBI
Celera785,042,762 - 85,544,656 (+)NCBICelera
Cytogenetic Map7q21.13NCBI
HuRef784,947,123 - 85,448,005 (+)NCBIHuRef
CHM1_1790,268,779 - 90,769,796 (+)NCBICHM1_1
T2T-CHM13v2.0791,844,591 - 92,458,441 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2789,669,510 - 90,170,369 (+)NCBI
Cdk14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3954,853,384 - 5,430,650 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl54,853,391 - 5,470,312 (-)EnsemblGRCm39 Ensembl
GRCm3854,803,384 - 5,380,251 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl54,803,391 - 5,420,312 (-)EnsemblGRCm38mm10GRCm38
MGSCv3754,803,385 - 5,380,251 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3654,809,739 - 5,386,203 (-)NCBIMGSCv36mm8
Celera54,734,602 - 5,327,038 (-)NCBICelera
Cytogenetic Map5A1NCBI
cM Map52.61NCBI
Cdk14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554327,787,600 - 8,335,726 (+)NCBIChiLan1.0ChiLan1.0
CDK14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26108,464,940 - 109,104,260 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17156,729,606 - 157,368,900 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0782,609,791 - 83,216,851 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1796,210,658 - 96,817,952 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl796,211,305 - 96,731,767 (+)Ensemblpanpan1.1panPan2
CDK14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11416,286,052 - 17,007,482 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1416,440,383 - 17,005,727 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1415,856,255 - 16,577,650 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01416,091,672 - 16,813,278 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1416,091,632 - 16,813,272 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11416,253,435 - 16,975,449 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01415,971,943 - 16,693,084 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01416,256,758 - 16,978,996 (+)NCBIUU_Cfam_GSD_1.0
Cdk14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511829,864,363 - 30,422,617 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366212,946,035 - 3,504,306 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366213,030,964 - 3,504,294 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl970,499,873 - 71,310,250 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1970,678,012 - 71,310,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2977,577,356 - 77,865,580 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12157,752,126 - 58,434,621 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2157,751,721 - 58,335,258 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604245,792,805 - 46,481,681 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248092,155,554 - 2,688,759 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248092,067,985 - 2,688,847 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Cdk14
2699 total Variants

Predicted Target Of
Summary Value
Count of predictions:889
Count of miRNA genes:316
Interacting mature miRNAs:431
Transcripts:ENSRNOT00000009417
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 37 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42133334339505420Rat

1 to 10 of 37 rows
ECD02012  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2428,828,189 - 28,829,145 (+)MAPPERmRatBN7.2
Rnor_6.0425,989,325 - 25,990,280NCBIRnor6.0
Rnor_5.0425,892,494 - 25,893,449UniSTSRnor5.0
RGSC_v3.4425,515,050 - 25,516,005UniSTSRGSC3.4
Celera424,269,092 - 24,270,047UniSTS
Cytogenetic Map4q12-q13UniSTS
REN110091  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2429,177,478 - 29,177,704 (+)MAPPERmRatBN7.2
Rnor_6.0426,338,060 - 26,338,285NCBIRnor6.0
Rnor_5.0426,245,062 - 26,245,287UniSTSRnor5.0
RGSC_v3.4425,861,619 - 25,861,844UniSTSRGSC3.4
Celera424,611,797 - 24,612,022UniSTS
Cytogenetic Map4q12-q13UniSTS
REN110146  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2429,189,877 - 29,190,114 (+)MAPPERmRatBN7.2
Rnor_6.0426,350,459 - 26,350,695NCBIRnor6.0
Rnor_5.0426,257,461 - 26,257,697UniSTSRnor5.0
RGSC_v3.4425,874,018 - 25,874,254UniSTSRGSC3.4
Celera424,624,196 - 24,624,432UniSTS
Cytogenetic Map4q12-q13UniSTS
REN110452  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2429,250,640 - 29,250,907 (+)MAPPERmRatBN7.2
Rnor_6.0426,411,219 - 26,411,485NCBIRnor6.0
Rnor_5.0426,318,213 - 26,318,479UniSTSRnor5.0
RGSC_v3.4425,934,778 - 25,935,044UniSTSRGSC3.4
Celera424,684,881 - 24,685,147UniSTS
Cytogenetic Map4q12-q13UniSTS
REN110453  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2429,250,895 - 29,251,139 (+)MAPPERmRatBN7.2
Rnor_6.0426,411,474 - 26,411,717NCBIRnor6.0
Rnor_5.0426,318,468 - 26,318,711UniSTSRnor5.0
RGSC_v3.4425,935,033 - 25,935,276UniSTSRGSC3.4
Celera424,685,136 - 24,685,379UniSTS
Cytogenetic Map4q12-q13UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000009417   ⟹   ENSRNOP00000009417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl428,666,843 - 29,258,861 (+)Ensembl
Rnor_6.0 Ensembl425,825,567 - 26,419,127 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094279   ⟹   ENSRNOP00000082191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl428,785,029 - 29,258,861 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116950   ⟹   ENSRNOP00000087492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl428,666,843 - 29,258,861 (+)Ensembl
RefSeq Acc Id: NM_001395582   ⟹   NP_001382511
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8429,621,217 - 30,213,651 (+)NCBI
mRatBN7.2428,666,416 - 29,258,865 (+)NCBI
RefSeq Acc Id: NM_001395583   ⟹   NP_001382512
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8429,621,217 - 30,146,381 (+)NCBI
mRatBN7.2428,666,416 - 29,191,598 (+)NCBI
RefSeq Acc Id: NM_001395584   ⟹   NP_001382513
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8429,739,811 - 30,213,651 (+)NCBI
mRatBN7.2428,785,024 - 29,258,865 (+)NCBI
RefSeq Acc Id: XM_039107757   ⟹   XP_038963685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8429,653,243 - 30,213,647 (+)NCBI
mRatBN7.2428,698,377 - 29,258,865 (+)NCBI
RefSeq Acc Id: XM_063286231   ⟹   XP_063142301
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8429,744,235 - 30,213,647 (+)NCBI
RefSeq Acc Id: XR_010065656
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8429,619,237 - 29,658,148 (+)NCBI
Ensembl Acc Id: ENSRNOP00000009417   ⟸   ENSRNOT00000009417
RefSeq Acc Id: XP_038963685   ⟸   XM_039107757
- Peptide Label: isoform X1
- UniProtKB: D3ZSZ0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000087492   ⟸   ENSRNOT00000116950
Ensembl Acc Id: ENSRNOP00000082191   ⟸   ENSRNOT00000094279
RefSeq Acc Id: NP_001382511   ⟸   NM_001395582
- Peptide Label: isoform 1
- UniProtKB: A0A8I6A7V5 (UniProtKB/TrEMBL),   D3ZSZ0 (UniProtKB/TrEMBL)
Protein kinase

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSZ0-F1-model_v2 AlphaFold D3ZSZ0 1-279 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13692839
Promoter ID:EPDNEW_R3364
Type:initiation region
Name:Cdk14_1
Description:cyclin-dependent kinase 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0425,825,735 - 25,825,795EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-45789 BioCyc
Ensembl Genes ENSRNOG00000007151 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009417.6 UniProtKB/TrEMBL
  ENSRNOT00000094279 ENTREZGENE
  ENSRNOT00000094279.1 UniProtKB/TrEMBL
  ENSRNOT00000116950 ENTREZGENE
  ENSRNOT00000116950.1 UniProtKB/TrEMBL
  ENSRNOT00000170629 ENTREZGENE
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro CDK UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene 362316 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/TrEMBL
  CYCLIN-DEPENDENT KINASE 14 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Cdk14 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007151 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A8I5ZUH6_RAT UniProtKB/TrEMBL
  A0A8I6A7V5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZSZ0 ENTREZGENE, UniProtKB/TrEMBL
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Cdk14  cyclin-dependent kinase 14  Pftk1  PFTAIRE protein kinase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pftk1  PFTAIRE protein kinase 1   Pftk1_predicted  PFTAIRE protein kinase 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pftk1_predicted  PFTAIRE protein kinase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED