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Gene: Plekhh2 (pleckstrin homology, MyTH4 and FERM domain containing H2) Rattus norvegicus

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Symbol:

Plekhh2

Name:

pleckstrin homology, MyTH4 and FERM domain containing H2

RGD ID:

1304935

Description:

Predicted to enable actin binding activity. Predicted to be involved in negative regulation of actin filament depolymerization. Predicted to be located in several cellular components, including cortical actin cytoskeleton; lamellipodium; and nuclear body. Predicted to be active in cytoplasm. Orthologous to human PLEKHH2 (pleckstrin homology, MyTH4 and FERM domain containing H2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC313866; pleckstrin homology domain containing, family H (with MyTH4 domain) member 2; pleckstrin homology domain-containing family H member 2; RGD1304935; similar to CG12467-PA

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	15,783,179 - 15,893,479 (-)	NCBI		GRCr8
mRatBN7.2	6	10,032,837 - 10,132,081 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	10,032,660 - 10,140,794 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	10,328,232 - 10,428,034 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	10,637,621 - 10,737,423 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	10,155,943 - 10,253,050 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	7,784,743 - 7,895,986 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	7,793,735 - 7,893,769 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	7,731,647 - 7,830,438 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	7,887,555 - 7,986,077 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	7,887,554 - 7,986,077 (+)	NCBI
Celera	6	9,753,640 - 9,852,005 (-)	NCBI		Celera
Cytogenetic Map	6	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Plekhh2	Rat	genetic disease		ISO	PLEKHH2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar
Plekhh2	Rat	Lynch syndrome		ISO	PLEKHH2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hereditary nonpolyposis colorectal neoplasms	ClinVar	PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Plekhh2	Rat	17alpha-ethynylestradiol	increases expression	ISO	Plekhh2 (Mus musculus)	6480464	Ethinyl Estradiol results in increased expression of PLEKHH2 mRNA	CTD	PMID:17942748
Plekhh2	Rat	17alpha-ethynylestradiol	multiple interactions	ISO	Plekhh2 (Mus musculus)	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PLEKHH2 mRNA	CTD	PMID:17942748
Plekhh2	Rat	17beta-estradiol	multiple interactions	ISO	PLEKHH2 (Homo sapiens)	6480464	EGF protein inhibits the reaction [Estradiol results in decreased expression of PLEKHH2 mRNA]	CTD	PMID:24758408
Plekhh2	Rat	17beta-estradiol	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Estradiol results in decreased expression of PLEKHH2 mRNA	CTD	PMID:24758408
Plekhh2	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	Plekhh2 (Mus musculus)	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PLEKHH2 mRNA	CTD	PMID:17942748
Plekhh2	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of PLEKHH2 mRNA	CTD	PMID:33387578
Plekhh2	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of PLEKHH2 mRNA	CTD	PMID:34747641
Plekhh2	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Tetrachlorodibenzodioxin results in decreased expression of PLEKHH2 mRNA	CTD	PMID:27913140
Plekhh2	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Plekhh2 (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of PLEKHH2 mRNA	CTD	PMID:21570461
Plekhh2	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	Plekhh2 (Mus musculus)	6480464	Tetrachlorodibenzodioxin results in increased expression of PLEKHH2 mRNA	CTD	PMID:19933214
Plekhh2	Rat	3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine	decreases expression	EXP		6480464	Puromycin Aminonucleoside results in decreased expression of PLEKHH2 protein	CTD	PMID:20588063
Plekhh2	Rat	3,3',5,5'-tetrabromobisphenol A	decreases expression	ISO	Plekhh2 (Mus musculus)	6480464	tetrabromobisphenol A results in decreased expression of PLEKHH2 mRNA	CTD	PMID:25172293
Plekhh2	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	Plekhh2 (Mus musculus)	6480464	bisphenol S results in increased expression of PLEKHH2 mRNA	CTD	PMID:30951980
Plekhh2	Rat	4,4'-sulfonyldiphenol	affects methylation	ISO	Plekhh2 (Mus musculus)	6480464	bisphenol S affects the methylation of PLEKHH2 gene	CTD	PMID:31683443
Plekhh2	Rat	4,4'-sulfonyldiphenol	multiple interactions	ISO	PLEKHH2 (Homo sapiens)	6480464	[bisphenol S co-treated with Fulvestrant] results in increased methylation of PLEKHH2 gene	CTD	PMID:31601247
Plekhh2	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of PLEKHH2 mRNA	CTD	PMID:24780913
Plekhh2	Rat	acetamide	increases expression	EXP		6480464	acetamide results in increased expression of PLEKHH2 mRNA	CTD	PMID:31881176
Plekhh2	Rat	aflatoxin B1	affects methylation	ISO	PLEKHH2 (Homo sapiens)	6480464	Aflatoxin B1 affects the methylation of PLEKHH2 intron	CTD	PMID:30157460
Plekhh2	Rat	Aflatoxin B2 alpha	increases methylation	ISO	PLEKHH2 (Homo sapiens)	6480464	aflatoxin B2 results in increased methylation of PLEKHH2 intron	CTD	PMID:30157460
Plekhh2	Rat	all-trans-retinoic acid	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Tretinoin results in decreased expression of PLEKHH2 mRNA	CTD	PMID:33167477
Plekhh2	Rat	alpha-Zearalanol	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PLEKHH2 mRNA	CTD	PMID:35163327
Plekhh2	Rat	aristolochic acid A	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	aristolochic acid I results in decreased expression of PLEKHH2 mRNA	CTD	PMID:33212167
Plekhh2	Rat	arsane	multiple interactions	ISO	PLEKHH2 (Homo sapiens)	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PLEKHH2 mRNA	CTD	PMID:39836092
Plekhh2	Rat	arsenic atom	multiple interactions	ISO	PLEKHH2 (Homo sapiens)	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PLEKHH2 mRNA	CTD	PMID:39836092
Plekhh2	Rat	atrazine	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Atrazine results in increased expression of PLEKHH2 mRNA	CTD	PMID:22378314
Plekhh2	Rat	benzo[a]pyrene	increases methylation	ISO	Plekhh2 (Mus musculus)	6480464	Benzo(a)pyrene results in increased methylation of PLEKHH2 exon and Benzo(a)pyrene results in increased methylation of PLEKHH2 intron	CTD	PMID:27901495
Plekhh2	Rat	benzo[a]pyrene	affects methylation	ISO	PLEKHH2 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of PLEKHH2 3' UTR and Benzo(a)pyrene affects the methylation of PLEKHH2 promoter	CTD	PMID:27901495
Plekhh2	Rat	benzo[e]pyrene	increases methylation	ISO	PLEKHH2 (Homo sapiens)	6480464	benzo(e)pyrene results in increased methylation of PLEKHH2 intron	CTD	PMID:30157460
Plekhh2	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Diethylhexyl Phthalate results in decreased expression of PLEKHH2 mRNA	CTD	PMID:31163220
Plekhh2	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of PLEKHH2 mRNA	CTD	PMID:25181051 and PMID:30816183
Plekhh2	Rat	bisphenol A	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	bisphenol A results in increased expression of PLEKHH2 mRNA	CTD	PMID:36232920
Plekhh2	Rat	bisphenol A	increases expression	ISO	Plekhh2 (Mus musculus)	6480464	bisphenol A results in increased expression of PLEKHH2 mRNA	CTD	PMID:30951980
Plekhh2	Rat	bisphenol F	increases expression	ISO	Plekhh2 (Mus musculus)	6480464	bisphenol F results in increased expression of PLEKHH2 mRNA	CTD	PMID:30951980
Plekhh2	Rat	cadmium atom	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Cadmium results in decreased expression of PLEKHH2 mRNA	CTD	PMID:24376830
Plekhh2	Rat	chlorpyrifos	decreases expression	ISO	Plekhh2 (Mus musculus)	6480464	Chlorpyrifos results in decreased expression of PLEKHH2 mRNA	CTD	PMID:37019170
Plekhh2	Rat	choline	multiple interactions	ISO	Plekhh2 (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PLEKHH2 gene	CTD	PMID:20938992
Plekhh2	Rat	cisplatin	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Cisplatin results in decreased expression of PLEKHH2 mRNA	CTD	PMID:27392435
Plekhh2	Rat	copper atom	increases expression	EXP		6480464	Copper deficiency results in increased expression of PLEKHH2 mRNA	CTD	PMID:26033743
Plekhh2	Rat	copper(0)	increases expression	EXP		6480464	Copper deficiency results in increased expression of PLEKHH2 mRNA	CTD	PMID:26033743
Plekhh2	Rat	curcumin	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Curcumin results in increased expression of PLEKHH2 mRNA	CTD	PMID:18421014
Plekhh2	Rat	cyclosporin A	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Cyclosporine results in increased expression of PLEKHH2 mRNA	CTD	PMID:25562108
Plekhh2	Rat	diclofenac	decreases expression	ISO	Plekhh2 (Mus musculus)	6480464	Diclofenac results in decreased expression of PLEKHH2 mRNA	CTD	PMID:35537566
Plekhh2	Rat	dimethylarsinic acid	decreases expression	EXP		6480464	Cacodylic Acid results in decreased expression of PLEKHH2 mRNA	CTD	PMID:37567419
Plekhh2	Rat	dimethylarsinous acid	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	dimethylarsinous acid results in decreased expression of PLEKHH2 mRNA	CTD	PMID:23487506
Plekhh2	Rat	dorsomorphin	multiple interactions	ISO	PLEKHH2 (Homo sapiens)	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ...	CTD	PMID:27188386
Plekhh2	Rat	doxorubicin	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Doxorubicin results in decreased expression of PLEKHH2 mRNA	CTD	PMID:29803840
Plekhh2	Rat	entinostat	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	entinostat results in increased expression of PLEKHH2 mRNA	CTD	PMID:27188386
Plekhh2	Rat	fenvalerate	increases expression	EXP		6480464	fenvalerate results in increased expression of PLEKHH2 mRNA	CTD	PMID:30307764
Plekhh2	Rat	folic acid	multiple interactions	ISO	Plekhh2 (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PLEKHH2 gene	CTD	PMID:20938992
Plekhh2	Rat	fulvestrant	multiple interactions	ISO	PLEKHH2 (Homo sapiens)	6480464	[bisphenol S co-treated with Fulvestrant] results in increased methylation of PLEKHH2 gene	CTD	PMID:31601247
Plekhh2	Rat	L-methionine	multiple interactions	ISO	Plekhh2 (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PLEKHH2 gene	CTD	PMID:20938992
Plekhh2	Rat	methapyrilene	increases methylation	ISO	PLEKHH2 (Homo sapiens)	6480464	Methapyrilene results in increased methylation of PLEKHH2 intron	CTD	PMID:30157460
Plekhh2	Rat	methylmercury chloride	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	methylmercuric chloride results in decreased expression of PLEKHH2 mRNA	CTD	PMID:28001369
Plekhh2	Rat	nickel atom	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Nickel results in decreased expression of PLEKHH2 mRNA	CTD	PMID:24768652
Plekhh2	Rat	nickel sulfate	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	nickel sulfate results in increased expression of PLEKHH2 mRNA	CTD	PMID:22714537
Plekhh2	Rat	paracetamol	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Acetaminophen results in increased expression of PLEKHH2 mRNA	CTD	PMID:22230336 and PMID:29067470
Plekhh2	Rat	paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of PLEKHH2 mRNA	CTD	PMID:33387578
Plekhh2	Rat	paraquat	decreases expression	EXP		6480464	Paraquat results in decreased expression of PLEKHH2 mRNA	CTD	PMID:32680482
Plekhh2	Rat	perfluorooctanoic acid	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PLEKHH2 mRNA	CTD	PMID:35163327
Plekhh2	Rat	phenethyl isothiocyanate	decreases expression	EXP		6480464	phenethyl isothiocyanate results in decreased expression of PLEKHH2 mRNA	CTD	PMID:17616710
Plekhh2	Rat	phenylmercury acetate	multiple interactions	ISO	PLEKHH2 (Homo sapiens)	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PLEKHH2 mRNA	CTD	PMID:27188386
Plekhh2	Rat	SB 431542	multiple interactions	ISO	PLEKHH2 (Homo sapiens)	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ...	CTD	PMID:27188386
Plekhh2	Rat	silicon dioxide	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Silicon Dioxide analog results in decreased expression of PLEKHH2 mRNA and Silicon Dioxide results in decreased expression of PLEKHH2 mRNA	CTD	PMID:25895662 and PMID:28425640
Plekhh2	Rat	silver atom	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Silver results in increased expression of PLEKHH2 mRNA	CTD	PMID:26014281
Plekhh2	Rat	silver(0)	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Silver results in increased expression of PLEKHH2 mRNA	CTD	PMID:26014281
Plekhh2	Rat	sodium arsenite	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	sodium arsenite results in increased expression of PLEKHH2 mRNA	CTD	PMID:22714537
Plekhh2	Rat	sodium arsenite	multiple interactions	ISO	PLEKHH2 (Homo sapiens)	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PLEKHH2 mRNA	CTD	PMID:39836092
Plekhh2	Rat	Soman	increases expression	EXP		6480464	Soman results in increased expression of PLEKHH2 mRNA	CTD	PMID:19281266
Plekhh2	Rat	testosterone	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Testosterone results in decreased expression of PLEKHH2 mRNA	CTD	PMID:33359661
Plekhh2	Rat	tetrachloromethane	decreases expression	EXP		6480464	Carbon Tetrachloride results in decreased expression of PLEKHH2 mRNA	CTD	PMID:31150632
Plekhh2	Rat	trichostatin A	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	trichostatin A results in increased expression of PLEKHH2 mRNA	CTD	PMID:24935251 and PMID:27188386
Plekhh2	Rat	trichostatin A	affects expression	ISO	PLEKHH2 (Homo sapiens)	6480464	trichostatin A affects the expression of PLEKHH2 mRNA	CTD	PMID:28542535
Plekhh2	Rat	trovafloxacin	decreases expression	ISO	Plekhh2 (Mus musculus)	6480464	trovafloxacin results in decreased expression of PLEKHH2 mRNA	CTD	PMID:35537566
Plekhh2	Rat	valproic acid	affects expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Valproic Acid affects the expression of PLEKHH2 mRNA	CTD	PMID:25979313
Plekhh2	Rat	valproic acid	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	Valproic Acid results in increased expression of PLEKHH2 mRNA	CTD	PMID:19101580 more ...
Plekhh2	Rat	valproic acid	multiple interactions	ISO	PLEKHH2 (Homo sapiens)	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLEKHH2 mRNA	CTD	PMID:27188386
Plekhh2	Rat	vorinostat	increases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	vorinostat results in increased expression of PLEKHH2 mRNA	CTD	PMID:27188386
Plekhh2	Rat	zoledronic acid	decreases expression	ISO	PLEKHH2 (Homo sapiens)	6480464	zoledronic acid results in decreased expression of PLEKHH2 mRNA	CTD	PMID:24714768

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Plekhh2	Rat	negative regulation of actin filament depolymerization	involved_in	ISO	Plekhh2 (Mus musculus)	1624291	PMID:22832517	RGD	PMID:22832517
Plekhh2	Rat	negative regulation of actin filament depolymerization	involved_in	IEA	UniProtKB:Q8C115 and ensembl:ENSMUSP00000039628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Plekhh2	Rat	negative regulation of actin filament depolymerization	involved_in	IBA	MGI:2146813 and PANTHER:PTN002740268	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Plekhh2	Rat	cortical actin cytoskeleton	located_in	ISO	Plekhh2 (Mus musculus)	1624291	PMID:22832517	RGD	PMID:22832517
Plekhh2	Rat	cortical actin cytoskeleton	located_in	IEA	UniProtKB:Q8C115 and ensembl:ENSMUSP00000039628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Plekhh2	Rat	cytoplasm	located_in	ISO	PLEKHH2 (Homo sapiens)	1624291	PMID:22832517	RGD	GO_REF:0000054 and PMID:22832517
Plekhh2	Rat	cytoplasm	located_in	IEA	UniProtKB:Q8IVE3 and ensembl:ENSP00000282406	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Plekhh2	Rat	cytoplasm	is_active_in	IBA	MGI:2146813 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Plekhh2	Rat	cytoskeleton	located_in	IEA	InterPro:IPR000299 and InterPro:IPR000857	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Plekhh2	Rat	cytosol	located_in	ISO	PLEKHH2 (Homo sapiens) and UniProtKB:Q8IVE3-1	1624291		RGD	GO_REF:0000052
Plekhh2	Rat	cytosol	located_in	IEA	UniProtKB:Q8IVE3 and ensembl:ENSP00000282406	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Plekhh2	Rat	lamellipodium	located_in	ISO	PLEKHH2 (Homo sapiens)	1624291	PMID:22832517	RGD	PMID:22832517
Plekhh2	Rat	lamellipodium	located_in	IEA	UniProtKB:Q8IVE3 and ensembl:ENSP00000282406	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Plekhh2	Rat	nuclear body	located_in	IEA	UniProtKB:Q8IVE3 and ensembl:ENSP00000282406	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Plekhh2	Rat	nuclear body	located_in	ISO	PLEKHH2 (Homo sapiens) and UniProtKB:Q8IVE3-1	1624291		RGD	GO_REF:0000052
Plekhh2	Rat	nucleoplasm	located_in	ISO	PLEKHH2 (Homo sapiens) and UniProtKB:Q8IVE3-1	1624291		RGD	GO_REF:0000052
Plekhh2	Rat	nucleoplasm	located_in	IEA	UniProtKB:Q8IVE3 and ensembl:ENSP00000282406	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Plekhh2	Rat	plasma membrane	located_in	ISO	PLEKHH2 (Homo sapiens) and UniProtKB:Q8IVE3-1	1624291		RGD	GO_REF:0000052
Plekhh2	Rat	plasma membrane	located_in	IEA	UniProtKB:Q8IVE3 and ensembl:ENSP00000282406	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Plekhh2	Rat	plasma membrane	located_in	ISO	PLEKHH2 (Homo sapiens)	1624291	PMID:22832517	RGD	PMID:22832517

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Plekhh2	Rat	actin binding	enables	IEA	UniProtKB:Q8C115 and ensembl:ENSMUSP00000039628	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Plekhh2	Rat	actin binding	enables	IBA	MGI:2146813 and PANTHER:PTN002740268	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Plekhh2	Rat	actin binding	enables	ISO	Plekhh2 (Mus musculus)	1624291	PMID:22832517	RGD	PMID:22832517
Plekhh2	Rat	protein binding	enables	ISO	Plekhh2 (Mus musculus)	1624291	UniProtKB:Q62219 and PMID:22832517	RGD	PMID:22832517
Plekhh2	Rat	protein binding	enables	ISO	PLEKHH2 (Homo sapiens) and UniProtKB:Q8IVE3-3	1624291	UniProtKB:P49023-2 and PMID:32296183	RGD	PMID:32296183
Plekhh2	Rat	protein binding	enables	ISO	PLEKHH2 (Homo sapiens)	1624291	UniProtKB:O60711 more ...	RGD	PMID:25416956 more ...

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:22832517

Plekhh2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	15,783,179 - 15,893,479 (-)	NCBI		GRCr8
mRatBN7.2	6	10,032,837 - 10,132,081 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	10,032,660 - 10,140,794 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	10,328,232 - 10,428,034 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	10,637,621 - 10,737,423 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	10,155,943 - 10,253,050 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	7,784,743 - 7,895,986 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	7,793,735 - 7,893,769 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	7,731,647 - 7,830,438 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	7,887,555 - 7,986,077 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	7,887,554 - 7,986,077 (+)	NCBI
Celera	6	9,753,640 - 9,852,005 (-)	NCBI		Celera
Cytogenetic Map	6	q12	NCBI

PLEKHH2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	43,637,260 - 43,767,987 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	43,637,260 - 43,767,987 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	43,864,399 - 43,995,126 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	43,717,951 - 43,848,630 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	43,776,097 - 43,906,776	NCBI
Celera	2	43,703,213 - 43,833,863 (+)	NCBI		Celera
Cytogenetic Map	2	p21	NCBI
HuRef	2	43,600,415 - 43,731,823 (+)	NCBI		HuRef
CHM1_1	2	43,794,022 - 43,924,517 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	43,642,678 - 43,773,318 (+)	NCBI		T2T-CHM13v2.0

Plekhh2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	84,819,303 - 84,929,571 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	84,819,323 - 84,929,566 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	84,511,895 - 84,622,143 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	84,511,895 - 84,622,138 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	84,911,235 - 85,021,482 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	84,420,221 - 84,530,455 (+)	NCBI		MGSCv36	mm8
Celera	17	88,877,452 - 88,989,118 (+)	NCBI		Celera
Cytogenetic Map	17	E4	NCBI
cM Map	17	55.02	NCBI

Plekhh2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955441	10,825,499 - 10,919,901 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955441	10,818,982 - 10,921,224 (+)	NCBI	ChiLan1.0	ChiLan1.0

PLEKHH2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	82,655,725 - 82,784,297 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	82,659,697 - 82,788,358 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	43,723,791 - 43,852,380 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	44,570,356 - 44,700,272 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	44,570,356 - 44,700,272 (+)	Ensembl	panpan1.1		panPan2

PLEKHH2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	46,113,659 - 46,226,259 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	46,114,348 - 46,224,363 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	45,975,843 - 46,087,889 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	46,992,023 - 47,104,761 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	46,992,060 - 47,103,049 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	46,700,351 - 46,813,125 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	46,990,837 - 47,103,309 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	47,173,714 - 47,286,463 (+)	NCBI		UU_Cfam_GSD_1.0

Plekhh2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	36,724,758 - 36,840,159 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936508	8,153,122 - 8,268,779 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936508	8,153,367 - 8,268,760 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLEKHH2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	96,709,059 - 96,833,410 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	96,707,397 - 96,833,431 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	102,783,515 - 102,863,985 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLEKHH2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	63,488,305 - 63,617,146 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	63,488,773 - 63,609,021 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	48,277,182 - 48,402,709 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Plekhh2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	25,123,506 - 25,239,175 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624738	25,122,843 - 25,240,304 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Plekhh2
1027 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	101
Count of miRNA genes:	82
Interacting mature miRNAs:	88
Transcripts:	ENSRNOT00000006832
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1	41223769	Rat
1549905	Stresp10	Stress response QTL 10	6.83	0.0066	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	6	1	27574569	Rat
8693699	Alc37	Alcohol consumption QTL 37	2.6	0.224	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	7964167	21301982	Rat
1331743	Uae28	Urinary albumin excretion QTL 28	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	1	34235784	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	5074497	54641141	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1	41223769	Rat
1578758	Tcas9	Tongue tumor susceptibility QTL 9	3.29		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	6	1	37618905	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	41223769	Rat
1598843	Cm63	Cardiac mass QTL 63	2.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	1	39036266	Rat
738024	Sach5	Saccharine consumption QTL 5	3.9	0.00039	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	6	1	43394190	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1	41223769	Rat
2293706	Bmd20	Bone mineral density QTL 20	4.3	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	5074497	19988050	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1	41223769	Rat
2292616	Ept15	Estrogen-induced pituitary tumorigenesis QTL 15	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	9843312	20338915	Rat
738023	Alc17	Alcohol consumption QTL 17	3.1	0.003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	6	1	27574569	Rat
1354616	Despr12	Despair related QTL 12		0.0012	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	6	1	27574569	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	1	42487980	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	1	42487980	Rat
7411584	Foco4	Food consumption QTL 4	4.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	42838846	Rat
2300176	Bmd51	Bone mineral density QTL 51	11.7	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	6	1	27574569	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	5074497	34434305	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	72227641	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	1	42487980	Rat
1358190	Ept1	Estrogen-induced pituitary tumorigenesis QTL 1	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	9843312	20338915	Rat
2300190	Bmd52	Bone mineral density QTL 52	11.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	6	1	27574569	Rat
8693690	Alc35	Alcohol consumption QTL 35	2.2	0.606	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	7964167	21301982	Rat

BF404107

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	10,104,101 - 10,104,278 (-)	MAPPER	mRatBN7.2
Rnor_6.0	6	7,821,732 - 7,821,908	NCBI	Rnor6.0
Rnor_6.0	6	7,734,558 - 7,734,734	NCBI	Rnor6.0
Rnor_5.0	6	7,673,754 - 7,673,930	UniSTS	Rnor5.0
Rnor_5.0	6	7,759,524 - 7,759,700	UniSTS	Rnor5.0
RGSC_v3.4	6	7,915,293 - 7,915,469	UniSTS	RGSC3.4
Celera	6	9,824,294 - 9,824,470	UniSTS
Cytogenetic Map	6	q12	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001191770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764462	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764463	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261830	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261831	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261832	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261837	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261838	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261840	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261841	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261847	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261849	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010052082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC120701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006832 ⟹ ENSRNOP00000006832

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	10,032,660 - 10,140,794 (-)	Ensembl
Rnor_6.0 Ensembl	6	7,793,855 - 7,893,519 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000090724 ⟹ ENSRNOP00000072102

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	6	7,793,735 - 7,893,769 (+)	Ensembl

RefSeq Acc Id:

NM_001191770 ⟹ NP_001178699

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,785,646 - 15,884,745 (-)	NCBI
mRatBN7.2	6	10,032,837 - 10,132,081 (-)	NCBI
Rnor_6.0	6	7,793,855 - 7,893,519 (+)	NCBI
Rnor_5.0	6	7,731,647 - 7,830,438 (+)	NCBI
Celera	6	9,753,640 - 9,852,005 (-)	NCBI

Sequence:

show sequence

ATGGAGGAGTCCTCTGANCCGGAAAGACCCATAGATTGGAAAGAACGCTGTGTAGCTCTGGAGGCTCAACTAATGAAATTCCGAGTTCAAGCAAGCAAGATCCGAGAGCTCCTAGCAGACAAAATGCA
ACAATTGGAGAGACAAGTCATCGATGCAGAACGCCAAGCAGAAAGGGCTTTTCAAGAGGTACAAGTTATGGAAGAGAAACTAAAAGCAGCTAACATTCAAACCAGTGAGTCAGAGACACGGCTATACA
AGAAGTGTCAAGATCTGGAGTCTGTGATGCAGGAGAAGGATGACCTCATTCAGAACTTGGCTCTGCGGCTTGAAGAGCAGAAACAAGTGAGGATAAAAGAAGCTAAAACAATAGAAGAAAAAGCAGCT
AAGATCAAAGAATGGGTAACAGTTAAATTAAACGAGCTAGAAGTAGAGAATCAGAATCTTCGTTTCATCAACCAAACCCAGACCGAAGAGCTAAGAGCAATACAGTCAAAATTGCAAGAACTCCAAGA
GAAGAAAGTATCCTGTGTCTCCAGCCCAAAGCCCTCAGAAGGGCAGCGTCTGAGCAGTTTGACGTTTGGATGCTTCTTGTCCCGAGCAAAGAGTCCGCCTTGTGCAGTAAGGTCCGAGGAAGCGAGCA
AGATGGCCTCAAGCGAACCTGAGTTCGCCGAAGCAAGATGCGTAGAAGAGATGGAAATTGCAGAGAAGCCTGCTGACAACCAAGTGCAAGAGAACAGCAGGAGCCAGAGAAAGTTGCTCGAGACCTCT
TGTGGCTCAGAACACAACCGGAAAACGGGAGCAAGCTTTGTAGCGGATGGTGGGACCCCCGAGCATTCTGGGCTTCCAGTGAGTGACTGGAGTTCAGACGATGACGACGGAAGCAAGGGCAGATCTAA
GTCCAGGTGCACGTCCACTCTTTCCAGCCACACGTCTGAGGAGGGTGGCCAGTGTGGCAGGCCGGGCAGCGAAGCTTATCTCACAGCATCCGATGACAGTAGTTCTATATTCGAGGAAGAGACTTTTG
ATGCTAACAGACCACAGCACAAGAAGCTGTATTCTTGGCAGCAGAAGGCACCATGGAAAGCTCCCAGTAACCTTGCAAAGGGAAGTTCTCAGTCAGAAGTTAAGCAGCGAGATAGTTCCTCAGATGAA
CTGAATAAGAAATTTCAGTCCCAGAGACTGGATTATTCATCCTCATCAAGCGAGGCCAACACCCCAAGCCCTATTTTAACCCCAGCTTTAACCCCCAAGCACCCTAACTCACTCCCTGGAAAAGGAAC
ACCATTAGTGCCTCCACCATTCCTGCCACCCCCAAAGCTGAGGATCCCCAACGTCTTCAGTATAAGTGTGGCACTGACCAAAAGGCACCTGAGCCAACCACAGTTATGTTCGGACCGGATGTTTGGCA
TGAACCGGAATGCCATCAGCATGATCCGGCCTCTGAGGCCTCAGGAAACGGACCTTGATATGGTTGATGGTGATAGGGCGGAAGCCGTGGACATCATGGACACGGGCTGCGGTGACTTATTTTCCTAT
GACTCCCAGGATCCTCCTTCTGCAGAAGACCCGGAAAACAGCGAGGCCACAAAGAAGGCCTCGTGCAGCAAACCCCCCACTCCTCCTTTGCACCGCTTCCCCTCTTGGGAGAGCAGGATTTATGCAGT
AGCCAAATCAGGCATCCGAGTGTCTGAGGCCTTCAATATGGAGAATGCTAATAAAAATGCTGCAAGCTTACTTTCCCACTCTGTAGCAGGCCCTTACATGTCTCTCATATACAAGAATGTGACGACCC
CTGTGTACACAACGTTGAAGGGGAAGGCGACACAAATAAGTACCAGCCCTTTCCTGGATGATTCTTCTGGCTCAGATGAAGAGGACGGTTCTAGGGCCAGCTCCCGGAGTCAGTCGGAGTCAGAAACG
CGCAGCCGCAGTGGACCGAACAGTCCCAGAGCCATGAAGCGAGGCGTGTCCGACTCTTCTGAGGGTGACTACGCCATCCCTCCGGATGCCTACTCCATAGACACGGAGTGCTCGCAGCCTGAGCAGAA
ACTCCTGAAAACCTGCTCGACGTCCAGTGACAACGGGAAAAGTGAGCTATTAGAAAAATCTGGCTACCTACTAAAAATGAGCGGACGACTCAAGACTTGGAGGCGGAGGTGGTTTGTTCTTAAAGGCG
GAGAACTACTTTACTACAGGTCTCCAAGCGATGTAATTCGGAAACCCCAGGGCCACATTGAACTTAGTGCATCCTGCAGTATTTTACGGGGAGATAACAAGCAAACGGTTCAGCTGACCACAGAGAAA
CACACATACTACCTGACAGCAGATTCTCCCAATATACTGGAAGAATGGATCAAAGTGTTCCAGAATGTTCTGCGAGTACAAGCTGCTAACCCTCTTTGCCTGCAGCCCGAGGGCAAACCCACAGTAAA
GGGCCTGCTCACCAAGGTAAAACACGGCTACTCTAAGAGAGTCTGGTGCACGCTTGTTGGAAAGTGCTTGTATTATTTTCGGAGTCAGGAGGATAAGTTCCCTCTAGGTCAGATCAAACTCTGGGAGG
CTAAGGTGGAGGAGGTGGACAGGTCATGTGACTCGGATGAGGACTATGAGACCAGTGGGCGCTGTCTGTTGTCCACTCACTACACCATCATTGTCCACCCCAAGGACCAGGGCCCTACTTACCTGCTC
ATCGGATCTAAGCACGAAAAGGAGGCGTGGCTTTATCACCTCACTGTTGCGGCTGGAAGCAACAATGTAAATGTTGGATCCGAATTTGAACAACTGGTTTGCAAACTGCTAAATATAGAAGGAGAGCC
CTCCTCCCAGATATGGAGACACCCCATGCTGTGTCACAGCAAAGAAGGAATCCTGTGCCCTCTGACCTCACTGCCTTCGGAAGCCCTGCAGACAGAGGCCATTAAGCTGTTTAAGACCTGCCAGCTCT
TTATCAACGCTGTGGTGGACTCCCCCGCCATCGACTACCATATCTCTCTGGCTCAGAGCGCTCTGCAGGTCTGCCTGACACATCCCGAGCTGCAGAGTGAAATTTGCTGTCAGCTTATTAAGCAGACC
AGGCGAAGACAGCAGCAGAATCAGGCCGGACCACTGCAGGGCTGGCAGCTCTTGGCGCTCTGCGTTGGACTCTTCCTTCCCCACCACCCTTTCCTGTGGCTCCTCCAGGTCCATCTGCAGAGGAGTGC
GGATTCCAGAACAGAATTTGGGAAATATGCCATTTACTGCCAGCGGTGTGTGGAAAGAACACTGCAAAACGGAGACCGAGAGGCCAGACCTTCCAGGATGGAGATCCTCTCCACCCTTCTTCGAAACC
CCTACCATCATTCTCGGCCCTTCAGCATTCCCGTGCACTTCATGAACGGGATCTACCAGGTAGTTGGGTTCGACGCGTCCACCACGGTGGAAGAATTTTTGAACACTTTGAACCAGGACACAGGAATG
AGGAAGCCAGCACAGTCCGGGTTCGCACTGTTCACAGATGACCCTTCTGGCAGAGACCTGGAACACTGTCTTCAGGGGAATATCAAGATCTGCGATATCATTTCTAAATGGGAGCAGGCATCCAAAGA
ACTGCAGCCCGGGAAGTGTGAGGGCAGCAGGACTGTCCGTCTGACTTACAAAAACAGACTATATTTTTCAATGCAAGCTCGTGGAGAGACTGACAGAGAGAAGCTGCTGCTGCTGTATCAGACAAATG
AGCAAATCATAAATGGTCTTTTCCCTCTCAACAAGGATCTGGCGTTAGAAATGGCAGCGCTCTTGGCTCAGGTGGATATCGGGGATTTTGAGAGACCGTTCTCAACTCCAGCTGGGCATGTGACCAAC
CAGTGCAAGGCAAACCAAACCCTCAAACAAGTCGTGGAGAAGTTTTACCCTAAAAGGTACCGAGAAGGGTGCTCTGAAGAACAGTTAAGGCAACTTTACCAGAGACTCTCGACCAGATGGATGGCCCT
CCGGGGACACAGCACAACTGACTGCATTCGCATTTACTTGACAGTAGCCAGGAAGTGGCCATTCTTTGGCGCCAAGTTATTCTTGGCCAAACCTATAACACCGTCATCACTTGGCAATAATTTTATCT
GGCTGGCTGTCCATGAAAACGGGTTGAGCATCCTAGAATACACCTCCATGAGGTTAGTGACTGGCTATGTGTACAAGAGTGTGATGACCTTTGGAGGCTATCAAGAGGATTTTATGGTAGTCATTAGT
ACACAGGCAAAAGACCGGCCAACAGAGAAGTTACTTTTCGCCATGGCAAAACCCAAGATTCTTGAAATTACCCTTCTGATCGCCAGTTACATCAACAACTTCTATCAGCAGAAGGCAGCATTTCACCA
CCTGTCTGCCCCGGCACTGCTCTCAGCCAAGGTTCAGGAGCCCCAAGCCAAGGCCATGGGCAGCCAGCCCCTTCTGTCCAACAACAGACCTACCAAAGGCCCCACCTTACTCTGA

hide sequence

RefSeq Acc Id:

XM_063261830 ⟹ XP_063117900

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,893,159 (-)	NCBI

RefSeq Acc Id:

XM_063261831 ⟹ XP_063117901

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,893,479 (-)	NCBI

RefSeq Acc Id:

XM_063261832 ⟹ XP_063117902

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,893,159 (-)	NCBI

RefSeq Acc Id:

XM_063261833 ⟹ XP_063117903

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,865,827 (-)	NCBI

RefSeq Acc Id:

XM_063261834 ⟹ XP_063117904

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,865,195 (-)	NCBI

RefSeq Acc Id:

XM_063261835 ⟹ XP_063117905

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,893,159 (-)	NCBI

RefSeq Acc Id:

XM_063261836 ⟹ XP_063117906

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,868,082 (-)	NCBI

RefSeq Acc Id:

XM_063261837 ⟹ XP_063117907

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,867,970 (-)	NCBI

RefSeq Acc Id:

XM_063261838 ⟹ XP_063117908

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,893,159 (-)	NCBI

RefSeq Acc Id:

XM_063261839 ⟹ XP_063117909

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,884,675 (-)	NCBI

RefSeq Acc Id:

XM_063261840 ⟹ XP_063117910

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,893,107 (-)	NCBI

RefSeq Acc Id:

XM_063261841 ⟹ XP_063117911

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,893,104 (-)	NCBI

RefSeq Acc Id:

XM_063261842 ⟹ XP_063117912

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,808,614 - 15,893,159 (-)	NCBI

RefSeq Acc Id:

XM_063261843 ⟹ XP_063117913

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,868,078 (-)	NCBI

RefSeq Acc Id:

XM_063261844 ⟹ XP_063117914

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,868,007 (-)	NCBI

RefSeq Acc Id:

XM_063261846 ⟹ XP_063117916

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,893,104 (-)	NCBI

RefSeq Acc Id:

XM_063261847 ⟹ XP_063117917

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,843,658 (-)	NCBI

RefSeq Acc Id:

XM_063261848 ⟹ XP_063117918

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,840,929 (-)	NCBI

RefSeq Acc Id:

XM_063261849 ⟹ XP_063117919

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,783,179 - 15,840,930 (-)	NCBI

RefSeq Acc Id:

XR_010052082

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	15,808,614 - 15,893,159 (-)	NCBI


Protein RefSeqs	NP_001178699	(Get FASTA)	NCBI Sequence Viewer
	XP_063117900	(Get FASTA)	NCBI Sequence Viewer
	XP_063117901	(Get FASTA)	NCBI Sequence Viewer
	XP_063117902	(Get FASTA)	NCBI Sequence Viewer
	XP_063117903	(Get FASTA)	NCBI Sequence Viewer
	XP_063117904	(Get FASTA)	NCBI Sequence Viewer
	XP_063117905	(Get FASTA)	NCBI Sequence Viewer
	XP_063117906	(Get FASTA)	NCBI Sequence Viewer
	XP_063117907	(Get FASTA)	NCBI Sequence Viewer
	XP_063117908	(Get FASTA)	NCBI Sequence Viewer
	XP_063117909	(Get FASTA)	NCBI Sequence Viewer
	XP_063117910	(Get FASTA)	NCBI Sequence Viewer
	XP_063117911	(Get FASTA)	NCBI Sequence Viewer
	XP_063117912	(Get FASTA)	NCBI Sequence Viewer
	XP_063117913	(Get FASTA)	NCBI Sequence Viewer
	XP_063117914	(Get FASTA)	NCBI Sequence Viewer
	XP_063117916	(Get FASTA)	NCBI Sequence Viewer
	XP_063117917	(Get FASTA)	NCBI Sequence Viewer
	XP_063117918	(Get FASTA)	NCBI Sequence Viewer
	XP_063117919	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM02697	(Get FASTA)	NCBI Sequence Viewer
	EDM02698	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006832
	ENSRNOP00000006832.5

RefSeq Acc Id:

NP_001178699 ⟸ NM_001191770

- UniProtKB:

D3ZNS6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEESSXPERPIDWKERCVALEAQLMKFRVQASKIRELLADKMQQLERQVIDAERQAERAFQEVQVMEEKLKAANIQTSESETRLYKKCQDLESVMQEKDDLIQNLALRLEEQKQVRIKEAKTIEEKAA
KIKEWVTVKLNELEVENQNLRFINQTQTEELRAIQSKLQELQEKKVSCVSSPKPSEGQRLSSLTFGCFLSRAKSPPCAVRSEEASKMASSEPEFAEARCVEEMEIAEKPADNQVQENSRSQRKLLETS
CGSEHNRKTGASFVADGGTPEHSGLPVSDWSSDDDDGSKGRSKSRCTSTLSSHTSEEGGQCGRPGSEAYLTASDDSSSIFEEETFDANRPQHKKLYSWQQKAPWKAPSNLAKGSSQSEVKQRDSSSDE
LNKKFQSQRLDYSSSSSEANTPSPILTPALTPKHPNSLPGKGTPLVPPPFLPPPKLRIPNVFSISVALTKRHLSQPQLCSDRMFGMNRNAISMIRPLRPQETDLDMVDGDRAEAVDIMDTGCGDLFSY
DSQDPPSAEDPENSEATKKASCSKPPTPPLHRFPSWESRIYAVAKSGIRVSEAFNMENANKNAASLLSHSVAGPYMSLIYKNVTTPVYTTLKGKATQISTSPFLDDSSGSDEEDGSRASSRSQSESET
RSRSGPNSPRAMKRGVSDSSEGDYAIPPDAYSIDTECSQPEQKLLKTCSTSSDNGKSELLEKSGYLLKMSGRLKTWRRRWFVLKGGELLYYRSPSDVIRKPQGHIELSASCSILRGDNKQTVQLTTEK
HTYYLTADSPNILEEWIKVFQNVLRVQAANPLCLQPEGKPTVKGLLTKVKHGYSKRVWCTLVGKCLYYFRSQEDKFPLGQIKLWEAKVEEVDRSCDSDEDYETSGRCLLSTHYTIIVHPKDQGPTYLL
IGSKHEKEAWLYHLTVAAGSNNVNVGSEFEQLVCKLLNIEGEPSSQIWRHPMLCHSKEGILCPLTSLPSEALQTEAIKLFKTCQLFINAVVDSPAIDYHISLAQSALQVCLTHPELQSEICCQLIKQT
RRRQQQNQAGPLQGWQLLALCVGLFLPHHPFLWLLQVHLQRSADSRTEFGKYAIYCQRCVERTLQNGDREARPSRMEILSTLLRNPYHHSRPFSIPVHFMNGIYQVVGFDASTTVEEFLNTLNQDTGM
RKPAQSGFALFTDDPSGRDLEHCLQGNIKICDIISKWEQASKELQPGKCEGSRTVRLTYKNRLYFSMQARGETDREKLLLLYQTNEQIINGLFPLNKDLALEMAALLAQVDIGDFERPFSTPAGHVTN
QCKANQTLKQVVEKFYPKRYREGCSEEQLRQLYQRLSTRWMALRGHSTTDCIRIYLTVARKWPFFGAKLFLAKPITPSSLGNNFIWLAVHENGLSILEYTSMRLVTGYVYKSVMTFGGYQEDFMVVIS
TQAKDRPTEKLLFAMAKPKILEITLLIASYINNFYQQKAAFHHLSAPALLSAKVQEPQAKAMGSQPLLSNNRPTKGPTLL

hide sequence

Ensembl Acc Id:

ENSRNOP00000006832 ⟸ ENSRNOT00000006832

Ensembl Acc Id:

ENSRNOP00000072102 ⟸ ENSRNOT00000090724

RefSeq Acc Id:	XP_063117901 ⟸ XM_063261831
- Peptide Label:	isoform X1
- UniProtKB:	D3ZNS6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063117902 ⟸ XM_063261832
- Peptide Label:	isoform X2
- UniProtKB:	D3ZNS6 (UniProtKB/TrEMBL)

Protein Domains

FERM MyTH4 PH

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K246-F1-model_v2	AlphaFold	A0A0G2K246	1-1514	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-38640	BioCyc
Ensembl Genes	ENSRNOG00000005124	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006832	ENTREZGENE
	ENSRNOT00000006832.5	UniProtKB/TrEMBL
Gene3D-CATH	1.20.80.10	UniProtKB/TrEMBL
	1.25.40.530	UniProtKB/TrEMBL
	2.30.29.30	UniProtKB/TrEMBL
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/TrEMBL
InterPro	Band_41_domain	UniProtKB/TrEMBL
	FERM/acyl-CoA-bd_prot_3-hlx	UniProtKB/TrEMBL
	FERM_2	UniProtKB/TrEMBL
	FERM_central	UniProtKB/TrEMBL
	FERM_domain	UniProtKB/TrEMBL
	MyTH4_dom	UniProtKB/TrEMBL
	MyTH4_dom_sf	UniProtKB/TrEMBL
	PH_like_dom	UniProtKB/TrEMBL
	Pleckstrin_homology	UniProtKB/TrEMBL
NCBI Gene	313866	ENTREZGENE
PANTHER	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 2	UniProtKB/TrEMBL
	PLEKHH PROTEIN	UniProtKB/TrEMBL
Pfam	FERM_M	UniProtKB/TrEMBL
	MyTH4	UniProtKB/TrEMBL
	PF00169	UniProtKB/TrEMBL
	RA_2	UniProtKB/TrEMBL
PhenoGen	Plekhh2	PhenoGen
PROSITE	FERM_3	UniProtKB/TrEMBL
	MYTH4	UniProtKB/TrEMBL
	PH_DOMAIN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000005124	RatGTEx
SMART	B41	UniProtKB/TrEMBL
	MyTH4	UniProtKB/TrEMBL
	SM00233	UniProtKB/TrEMBL
Superfamily-SCOP	FERM_3-hlx	UniProtKB/TrEMBL
	PH domain-like	UniProtKB/TrEMBL
UniProt	D3ZNS6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-30	Plekhh2	pleckstrin homology, MyTH4 and FERM domain containing H2	Plekhh2	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-04	Plekhh2	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2	RGD1304935_predicted	similar to CG12467-PA (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1304935_predicted	similar to CG12467-PA (predicted)	LOC313866_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC313866_predicted	similar to CG12467-PA (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar