Tbx15 (T-box transcription factor 15) - Rat Genome Database

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Gene: Tbx15 (T-box transcription factor 15) Chinchilla lanigera
Analyze
Symbol: Tbx15
Name: T-box transcription factor 15
RGD ID: 9017690
Description: ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); protein homodimerization activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN embryonic cranial skeleton morphogenesis (ortholog); embryonic skeletal system morphogenesis (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Cousin Syndrome (ortholog); Craniofacial Abnormalities (ortholog); genetic disease (ortholog); FOUND IN nucleus (ortholog); RNA polymerase II transcription repressor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: T-box 15; T-box transcription factor TBX15
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543521,872,201 - 21,993,772 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543521,874,154 - 21,993,510 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tbx15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543521,872,201 - 21,993,772 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543521,874,154 - 21,993,510 (-)NCBIChiLan1.0ChiLan1.0
TBX15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381118,883,047 - 118,989,510 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1118,883,046 - 118,989,556 (-)EnsemblGRCh38hg38GRCh38
GRCh371119,425,670 - 119,532,133 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361119,227,189 - 119,333,702 (-)NCBINCBI36Build 36hg18NCBI36
Build 341119,137,707 - 119,244,221NCBI
Celera1117,656,516 - 117,763,011 (-)NCBICelera
Cytogenetic Map1p12NCBI
HuRef1117,284,782 - 117,391,248 (-)NCBIHuRef
CHM1_11119,540,937 - 119,647,437 (-)NCBICHM1_1
T2T-CHM13v2.01118,896,253 - 119,002,693 (-)NCBIT2T-CHM13v2.0
Tbx15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39399,147,671 - 99,261,576 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl399,147,697 - 99,261,575 (+)EnsemblGRCm39 Ensembl
GRCm38399,240,348 - 99,354,260 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl399,240,381 - 99,354,259 (+)EnsemblGRCm38mm10GRCm38
MGSCv37399,057,683 - 99,158,183 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36399,377,677 - 99,483,320 (+)NCBIMGSCv36mm8
Celera3101,519,902 - 101,565,343 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map343.03NCBI
Tbx15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82189,265,373 - 189,376,466 (+)NCBIGRCr8
mRatBN7.22186,576,650 - 186,687,748 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2186,576,676 - 186,687,663 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2194,242,381 - 194,346,970 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02192,056,074 - 192,161,040 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02186,874,659 - 186,979,606 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02201,289,042 - 201,390,752 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2201,289,357 - 201,390,745 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02220,754,497 - 220,855,862 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42194,015,902 - 194,069,012 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12193,899,549 - 194,032,556 (+)NCBI
Celera2179,111,401 - 179,157,133 (+)NCBICelera
Cytogenetic Map2q34NCBI
TBX15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,507,196 - 111,625,489 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11111,111,200 - 111,216,427 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0183,556,763 - 83,663,453 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11118,554,476 - 118,659,379 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1118,553,638 - 118,659,379 (+)Ensemblpanpan1.1panPan2
TBX15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11756,079,739 - 56,190,417 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1756,081,411 - 56,204,192 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1755,728,743 - 55,839,376 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01756,952,138 - 57,062,859 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1756,953,811 - 57,077,185 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11755,989,587 - 56,099,313 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01756,021,008 - 56,131,283 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01756,610,873 - 56,721,034 (-)NCBIUU_Cfam_GSD_1.0
Tbx15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505810,635,685 - 10,743,606 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366273,745,287 - 3,853,309 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366273,745,399 - 3,852,861 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBX15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.14101,918,891 - 102,032,280 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24111,987,664 - 112,036,804 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBX15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12014,762,073 - 14,870,417 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2014,818,525 - 14,871,196 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603817,429,839 - 17,537,813 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbx15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477214,482,948 - 14,611,452 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477214,483,951 - 14,611,602 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000012156   ⟹   ENSCLAP00000012015
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543521,872,201 - 21,993,772 (-)Ensembl
RefSeq Acc Id: XM_005389071   ⟹   XP_005389128
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543521,874,154 - 21,993,510 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005389072   ⟹   XP_005389129
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543521,874,154 - 21,944,751 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005389128 (Get FASTA)   NCBI Sequence Viewer  
  XP_005389129 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000012015
  ENSCLAP00000012015.1
Reference Protein Sequences
RefSeq Acc Id: XP_005389128   ⟸   XM_005389071
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VFN8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005389129   ⟸   XM_005389072
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000012015   ⟸   ENSCLAT00000012156
Protein Domains
T-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000008292 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000012156 ENTREZGENE
  ENSCLAT00000012156.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.820 UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/TrEMBL
  T-box_DNA-bd UniProtKB/TrEMBL
  T-box_sf UniProtKB/TrEMBL
  TF_T-box UniProtKB/TrEMBL
  TF_T-box_CS UniProtKB/TrEMBL
NCBI Gene Tbx15 ENTREZGENE
PANTHER PTHR11267 UniProtKB/TrEMBL
  T-BOX TRANSCRIPTION FACTOR TBX15 UniProtKB/TrEMBL
Pfam T-box UniProtKB/TrEMBL
PRINTS TBOX UniProtKB/TrEMBL
PROSITE TBOX_1 UniProtKB/TrEMBL
  TBOX_2 UniProtKB/TrEMBL
  TBOX_3 UniProtKB/TrEMBL
SMART TBOX UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/TrEMBL
UniProt A0A8C2VFN8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-06-11 Tbx15  T-box transcription factor 15  Tbx15  T-box 15  Symbol and/or name change 5135510 APPROVED