TBX15 (T-box transcription factor 15) - Rat Genome Database

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Gene: TBX15 (T-box transcription factor 15) Pan paniscus
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Symbol: TBX15
Name: T-box transcription factor 15
RGD ID: 11693260
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN cell fate specification (inferred); embryonic cranial skeleton morphogenesis (inferred); embryonic skeletal system morphogenesis (inferred); ASSOCIATED WITH Cousin Syndrome (ortholog); Craniofacial Abnormalities (ortholog); genetic disease (ortholog); FOUND IN chromatin (inferred); nucleus (inferred); RNA polymerase II transcription repressor complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC130541643; T-box 15; T-box transcription factor TBX15; uncharacterized LOC130541643
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,507,196 - 111,625,489 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11111,111,200 - 111,216,427 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0183,556,763 - 83,663,453 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11118,554,476 - 118,659,379 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1118,553,638 - 118,659,379 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBX15BonoboCousin Syndrome  ISOTBX15 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:19068278 more ...
TBX15Bonobogenetic disease  ISOTBX15 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
TBX15BonoboHajdu-Cheney syndrome  ISOTBX15 (Homo sapiens)8554872ClinVar Annotator: match by term: Hajdu-Cheney syndromeClinVarPMID:28492532
TBX15BonoboPHGDH deficiency  ISOTBX15 (Homo sapiens)8554872ClinVar Annotator: match by term: PHGDH deficiencyClinVarPMID:14645240 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBX15BonoboCraniofacial Abnormalities  ISOTBX15 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:19068278
TBX15BonoboGrowth Disorders  ISOTBX15 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:19068278
TBX15BonoboNeoplasm Invasiveness  ISOTBX15 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:26213588
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBX15BonoboCousin Syndrome  ISOTBX15 (Homo sapiens)7240710 OMIM 


Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBX15Bonobochromatin located_inIEAPANTHER:PTN000138167 and PANTHER:PTN002601304150520179 TreeGrafterGO_REF:0000118
TBX15Bonobonucleus located_inIEAUniRule:UR000400702150520179 UniProtGO_REF:0000104
TBX15Bonobonucleus located_inIEAPANTHER:PTN000138167 and PANTHER:PTN002601304150520179 TreeGrafterGO_REF:0000118
TBX15Bonobonucleus located_inIEAUniProtKB:O70306 and ensembl:ENSMUSP00000029462150520179 EnsemblGO_REF:0000107
TBX15Bonobonucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
TBX15Bonobonucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
TBX15Bonobonucleus located_inIEAInterPro:IPR018186 and InterPro:IPR036960150520179 InterProGO_REF:0000002
TBX15BonoboRNA polymerase II transcription repressor complex part_ofIEAUniProtKB:O70306 and ensembl:ENSMUSP00000029462150520179 EnsemblGO_REF:0000107

Molecular Function
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBX15BonoboDNA binding enablesIEAUniRule:UR000400702150520179 UniProtGO_REF:0000104
TBX15BonoboDNA binding enablesIEAUniProtKB-KW:KW-0238150520179 UniProtGO_REF:0000043
TBX15BonoboDNA-binding transcription factor activity enablesIEAInterPro:IPR001699 more ...150520179 InterProGO_REF:0000002
TBX15BonoboDNA-binding transcription factor activity, RNA polymerase II-specific enablesIEAPANTHER:PTN000138167 and PANTHER:PTN002601304150520179 TreeGrafterGO_REF:0000118
TBX15BonoboDNA-binding transcription repressor activity, RNA polymerase II-specific enablesIEAUniProtKB:O70306 and ensembl:ENSMUSP00000029462150520179 EnsemblGO_REF:0000107
TBX15Bonoboprotein binding enablesISOUniProtKB:A8MV65-2 more ...9068941 PMID:32296183IntActPMID:32296183
TBX15Bonoboprotein binding enablesISOPR:Q9EPZ69068941 PMID:17584735MGIPMID:17584735
TBX15Bonoboprotein binding enablesISOUniProtKB:O952319068941 PMID:31515488IntActPMID:31515488
TBX15Bonoboprotein binding enablesISOUniProtKB:O95231 more ...9068941 PMID:25416956IntActPMID:25416956
TBX15Bonoboprotein homodimerization activity enablesIEAUniProtKB:O70306 and ensembl:ENSMUSP00000029462150520179 EnsemblGO_REF:0000107
TBX15BonoboRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIEAUniProtKB:O70306 and ensembl:ENSMUSP00000029462150520179 EnsemblGO_REF:0000107
TBX15BonoboRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIEAPANTHER:PTN000138167 and PANTHER:PTN002601304150520179 TreeGrafterGO_REF:0000118
TBX15BonoboRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIEAInterPro:IPR001699150520179 InterProGO_REF:0000002
TBX15Bonobosequence-specific double-stranded DNA binding enablesIEAUniProtKB:Q96SF7 and ensembl:ENSP00000358437150520179 EnsemblGO_REF:0000107
1 to 14 of 14 rows

PMID:22301074   PMID:30032202  



TBX15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,507,196 - 111,625,489 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11111,111,200 - 111,216,427 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0183,556,763 - 83,663,453 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11118,554,476 - 118,659,379 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1118,553,638 - 118,659,379 (+)Ensemblpanpan1.1panPan2
TBX15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381118,883,047 - 118,989,510 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1118,883,046 - 118,989,556 (-)EnsemblGRCh38hg38GRCh38
GRCh371119,425,670 - 119,532,133 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361119,227,189 - 119,333,702 (-)NCBINCBI36Build 36hg18NCBI36
Build 341119,137,707 - 119,244,221NCBI
Celera1117,656,516 - 117,763,011 (-)NCBICelera
Cytogenetic Map1p12NCBI
HuRef1117,284,782 - 117,391,248 (-)NCBIHuRef
CHM1_11119,540,937 - 119,647,437 (-)NCBICHM1_1
T2T-CHM13v2.01118,896,253 - 119,002,693 (-)NCBIT2T-CHM13v2.0
Tbx15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39399,147,671 - 99,261,576 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl399,147,697 - 99,261,575 (+)EnsemblGRCm39 Ensembl
GRCm38399,240,348 - 99,354,260 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl399,240,381 - 99,354,259 (+)EnsemblGRCm38mm10GRCm38
MGSCv37399,057,683 - 99,158,183 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36399,377,677 - 99,483,320 (+)NCBIMGSCv36mm8
Celera3101,519,902 - 101,565,343 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map343.03NCBI
Tbx15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82189,265,373 - 189,376,466 (+)NCBIGRCr8
mRatBN7.22186,576,650 - 186,687,748 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2186,576,676 - 186,687,663 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2194,242,381 - 194,346,970 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02192,056,074 - 192,161,040 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02186,874,659 - 186,979,606 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02201,289,042 - 201,390,752 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2201,289,357 - 201,390,745 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02220,754,497 - 220,855,862 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42194,015,902 - 194,069,012 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12193,899,549 - 194,032,556 (+)NCBI
Celera2179,111,401 - 179,157,133 (+)NCBICelera
Cytogenetic Map2q34NCBI
Tbx15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543521,872,201 - 21,993,772 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543521,874,154 - 21,993,510 (-)NCBIChiLan1.0ChiLan1.0
TBX15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11756,079,739 - 56,190,417 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1756,081,411 - 56,204,192 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1755,728,743 - 55,839,376 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01756,952,138 - 57,062,859 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1756,953,811 - 57,077,185 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11755,989,587 - 56,099,313 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01756,021,008 - 56,131,283 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01756,610,873 - 56,721,034 (-)NCBIUU_Cfam_GSD_1.0
Tbx15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505810,635,685 - 10,743,606 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366273,745,287 - 3,853,309 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366273,745,399 - 3,852,861 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBX15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.14101,918,891 - 102,032,280 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24111,987,664 - 112,036,804 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBX15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12014,762,073 - 14,870,417 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2014,818,525 - 14,871,196 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603817,429,839 - 17,537,813 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbx15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477214,482,948 - 14,611,452 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477214,483,951 - 14,611,602 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSPPAT00000048513   ⟹   ENSPPAP00000025684
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1118,553,638 - 118,659,379 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000048522   ⟹   ENSPPAP00000025692
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1118,554,476 - 118,621,566 (+)Ensembl
RefSeq Acc Id: XM_003806294   ⟹   XP_003806342
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,507,196 - 111,613,653 (-)NCBI
NHGRI_mPanPan11111,111,200 - 111,216,427 (-)NCBI
Mhudiblu_PPA_v0183,558,192 - 83,663,453 (+)NCBI
PanPan1.11118,554,476 - 118,659,379 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055114442   ⟹   XP_054970417
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,507,196 - 111,612,452 (-)NCBI
NHGRI_mPanPan11111,111,201 - 111,216,386 (-)NCBI
RefSeq Acc Id: XM_063599353   ⟹   XP_063455423
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,507,196 - 111,612,435 (-)NCBI
RefSeq Acc Id: XM_063599366   ⟹   XP_063455436
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,507,196 - 111,612,435 (-)NCBI
RefSeq Acc Id: XM_063599367   ⟹   XP_063455437
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,507,196 - 111,625,489 (-)NCBI
RefSeq Acc Id: XM_063599370   ⟹   XP_063455440
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,507,196 - 111,607,748 (-)NCBI
Protein RefSeqs XP_003806342 (Get FASTA)   NCBI Sequence Viewer  
  XP_054970417 (Get FASTA)   NCBI Sequence Viewer  
  XP_063455423 (Get FASTA)   NCBI Sequence Viewer  
  XP_063455436 (Get FASTA)   NCBI Sequence Viewer  
  XP_063455437 (Get FASTA)   NCBI Sequence Viewer  
  XP_063455440 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000025684.1
  ENSPPAP00000025692.1
RefSeq Acc Id: XP_003806342   ⟸   XM_003806294
- Peptide Label: isoform X4
- UniProtKB: A0A2R9B7V9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000025684   ⟸   ENSPPAT00000048513
Ensembl Acc Id: ENSPPAP00000025692   ⟸   ENSPPAT00000048522
RefSeq Acc Id: XP_054970417   ⟸   XM_055114442
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B7V9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063455437   ⟸   XM_063599367
- Peptide Label: isoform X5
- UniProtKB: A0A2R9B7V9 (UniProtKB/TrEMBL)
T-box



1 to 22 of 22 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000035967 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048513.1 UniProtKB/TrEMBL
  ENSPPAT00000048522.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.820 UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/TrEMBL
  T-box_DNA-bd UniProtKB/TrEMBL
  T-box_sf UniProtKB/TrEMBL
  TF_T-box UniProtKB/TrEMBL
  TF_T-box_CS UniProtKB/TrEMBL
KEGG Report pps:100979284 UniProtKB/TrEMBL
NCBI Gene TBX15 ENTREZGENE
PANTHER PTHR11267 UniProtKB/TrEMBL
  T-BOX TRANSCRIPTION FACTOR TBX15 UniProtKB/TrEMBL
Pfam T-box UniProtKB/TrEMBL
PRINTS TBOX UniProtKB/TrEMBL
PROSITE TBOX_1 UniProtKB/TrEMBL
  TBOX_2 UniProtKB/TrEMBL
  TBOX_3 UniProtKB/TrEMBL
SMART TBOX UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/TrEMBL
UniProt A0A2R9B7V9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B9D0_PANPA UniProtKB/TrEMBL
1 to 22 of 22 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-03-14 TBX15  T-box transcription factor 15  LOC130541643  uncharacterized LOC130541643  Data Merged 737654 PROVISIONAL
2019-06-11 TBX15  T-box transcription factor 15  TBX15  T-box 15  Symbol and/or name change 5135510 APPROVED