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Gene: Tbx15 (T-box 15) Mus musculus
Symbol: Tbx15
Name: T-box 15
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and protein dimerization activity. Involved in embryonic cranial skeleton morphogenesis and negative regulation of transcription by RNA polymerase II. Localizes to the nucleus. Colocalizes with the Tle3-Aes complex. Is expressed in several structures, including branchial arch; ear; embryo mesenchyme; genitourinary system; and limb. Orthologous to human TBX15 (T-box transcription factor 15); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: de; droopy ear; mmTBx8; T-box 14; T-box protein 14; T-box protein 15; T-box transcription factor TBX14; T-box transcription factor TBX15; Tbx14; Tbx8
Homo sapiens (human) : TBX15 (T-box transcription factor 15)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tbx15 (T-box transcription factor 15)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbx15 (T-box transcription factor 15)
Pan paniscus (bonobo/pygmy chimpanzee) : TBX15 (T-box transcription factor 15)
Canis lupus familiaris (dog) : TBX15 (T-box transcription factor 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbx15 (T-box transcription factor 15)
Sus scrofa (pig) : TBX15 (T-box transcription factor 15)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl399,240,381 - 99,354,259 (+)Ensembl
GRCm38399,240,348 - 99,354,260 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37399,057,683 - 99,158,183 (+)NCBIGRCm37mm9NCBIm37
MGSCv36399,377,677 - 99,483,320 (+)NCBImm8
Celera3101,519,902 - 101,565,343 (+)NCBICelera
Cytogenetic Map3 F2.2NCBI
cM Map343.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tbx15
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557550
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.