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Gene: Tbx15 (T-box 15) Mus musculus
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Symbol: Tbx15
Name: T-box 15
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and protein dimerization activity. Involved in embryonic cranial skeleton morphogenesis and negative regulation of transcription by RNA polymerase II. Localizes to the nucleus. Colocalizes with the Tle3-Aes complex. Is expressed in several structures, including branchial arch; ear; embryo mesenchyme; genitourinary system; and limb. Orthologous to human TBX15 (T-box transcription factor 15); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: de; droopy ear; mmTBx8; T-box 14; T-box protein 14; T-box protein 15; T-box transcription factor TBX14; T-box transcription factor TBX15; Tbx14; Tbx8
Orthologs:
Homo sapiens (human) : TBX15 (T-box transcription factor 15)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tbx15 (T-box transcription factor 15)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbx15 (T-box transcription factor 15)
Pan paniscus (bonobo/pygmy chimpanzee) : TBX15 (T-box transcription factor 15)
Canis lupus familiaris (dog) : TBX15 (T-box transcription factor 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbx15 (T-box transcription factor 15)
Sus scrofa (pig) : TBX15 (T-box transcription factor 15)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl399,240,381 - 99,354,259 (+)Ensembl
GRCm38399,240,348 - 99,354,260 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37399,057,683 - 99,158,183 (+)NCBIGRCm37mm9NCBIm37
MGSCv36399,377,677 - 99,483,320 (+)NCBImm8
Celera3101,519,902 - 101,565,343 (+)NCBICelera
Cytogenetic Map3 F2.2NCBI
cM Map343.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tbx15
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557550
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.