Nalcn (sodium leak channel, non-selective) - Rat Genome Database

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Gene: Nalcn (sodium leak channel, non-selective) Chinchilla lanigera
Analyze
Symbol: Nalcn
Name: sodium leak channel, non-selective
RGD ID: 8867015
Description: ENCODES a protein that exhibits cation channel activity (ortholog); leak channel activity (ortholog); voltage-gated sodium channel activity (ortholog); INVOLVED IN calcium ion transmembrane transport (ortholog); potassium ion transmembrane transport (ortholog); regulation of resting membrane potential (ortholog); ASSOCIATED WITH Anal Atresia, Hypospadias, and Penoscrotal Inversion (ortholog); autism spectrum disorder (ortholog); congenital limbs-face contractures-hypotonia-developmental delay syndrome (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium leak channel, non selective
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554049,603,562 - 9,895,817 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554049,603,567 - 9,894,688 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data
Nalcn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554049,603,562 - 9,895,817 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554049,603,567 - 9,894,688 (+)NCBIChiLan1.0ChiLan1.0
NALCN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813101,053,776 - 101,417,179 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl13101,053,776 - 101,416,508 (-)EnsemblGRCh38hg38GRCh38
GRCh3713101,706,128 - 102,068,859 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3613100,504,131 - 100,866,814 (-)NCBINCBI36hg18NCBI36
Build 3413100,505,600 - 100,866,707NCBI
Celera1382,551,415 - 82,911,536 (-)NCBI
Cytogenetic Map13q32.3-q33.1NCBI
HuRef1382,301,975 - 82,662,087 (-)NCBIHuRef
CHM1_113101,676,115 - 102,038,862 (-)NCBICHM1_1
T2T-CHM13v2.013100,268,892 - 100,631,686 (-)NCBI
Nalcn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914123,514,046 - 123,864,846 (-)NCBIGRCm39mm39
GRCm39 Ensembl14123,514,046 - 123,864,556 (-)Ensembl
GRCm3814123,275,678 - 123,627,330 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14123,276,634 - 123,627,144 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714123,675,863 - 124,026,366 (-)NCBIGRCm37mm9NCBIm37
MGSCv3614122,434,608 - 122,762,324 (-)NCBImm8
Celera14121,838,270 - 121,890,033 (-)NCBICelera
Celera14122,811,564 - 123,084,265 (-)NCBICelera
Cytogenetic Map14E5NCBI
Nalcn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.215100,398,615 - 100,712,283 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl15100,398,615 - 100,741,001 (-)Ensembl
Rnor_6.015109,734,092 - 110,046,729 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15109,735,595 - 110,046,704 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015113,115,691 - 113,426,241 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415108,414,286 - 108,658,195 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.115108,430,065 - 108,673,975 (-)NCBI
Celera1599,154,725 - 99,456,878 (-)NCBICelera
Cytogenetic Map15q25NCBI
NALCN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.113101,352,535 - 101,710,917 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13101,354,054 - 101,693,223 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01382,215,094 - 82,573,501 (-)NCBIMhudiblu_PPA_v0panPan3
NALCN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12250,821,983 - 51,142,000 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2250,823,478 - 51,141,644 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2250,601,806 - 50,922,190 (-)NCBI
ROS_Cfam_1.02251,265,000 - 51,586,596 (-)NCBI
ROS_Cfam_1.0 Ensembl2251,265,007 - 51,586,235 (-)Ensembl
UMICH_Zoey_3.12250,910,597 - 51,250,150 (-)NCBI
UNSW_CanFamBas_1.02250,941,445 - 51,259,292 (-)NCBI
UU_Cfam_GSD_1.02250,984,648 - 51,306,587 (-)NCBI
Nalcn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945186,162,530 - 186,450,079 (-)NCBI
SpeTri2.0NW_0049364729,502,054 - 9,789,714 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NALCN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1169,710,364 - 70,022,727 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11169,710,355 - 70,023,020 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NALCN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1379,663,714 - 80,010,361 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl379,663,725 - 79,992,503 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604636,176,805 - 36,522,145 (-)NCBIVero_WHO_p1.0
Nalcn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247939,915,273 - 10,249,563 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247939,929,980 - 10,248,107 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005400   ⟹   ENSCLAP00000005304
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554049,603,562 - 9,895,817 (+)Ensembl
RefSeq Acc Id: XM_005374037   ⟹   XP_005374094
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554049,603,567 - 9,894,688 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005374038   ⟹   XP_005374095
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554049,603,606 - 9,894,001 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005374039   ⟹   XP_005374096
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554049,603,567 - 9,894,688 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515982   ⟹   XP_013371436
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554049,603,567 - 9,894,688 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005374094 (Get FASTA)   NCBI Sequence Viewer  
  XP_005374095 (Get FASTA)   NCBI Sequence Viewer  
  XP_005374096 (Get FASTA)   NCBI Sequence Viewer  
  XP_013371436 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005374094   ⟸   XM_005374037
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005374095   ⟸   XM_005374038
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005374096   ⟸   XM_005374039
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013371436   ⟸   XM_013515982
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000005304   ⟸   ENSCLAT00000005400
Protein Domains
Ion_trans


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003764 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000005304 ENTREZGENE
  ENSCLAP00000005304.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005400 ENTREZGENE
  ENSCLAT00000005400.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.350 UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  NALCN UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene Nalcn ENTREZGENE
PANTHER PTHR46141 UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
UniProt A0A8C2UU75_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Nalcn  sodium leak channel, non-selective    sodium leak channel, non selective  Symbol and/or name change 5135510 APPROVED
2015-08-25 Nalcn  sodium leak channel, non selective    sodium leak channel, non-selective  Symbol and/or name change 5135510 APPROVED