Fbxo6 (F-box protein 6) - Rat Genome Database

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Gene: Fbxo6 (F-box protein 6) Chinchilla lanigera
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Symbol: Fbxo6
Name: F-box protein 6
RGD ID: 8850681
Description: ENCODES a protein that exhibits carbohydrate binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN ERAD pathway (ortholog); glycoprotein catabolic process (ortholog); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); chromosome 1p36 deletion syndrome (ortholog); Familial Atrial Fibrillation 6 (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum quality control compartment (ortholog); SCF ubiquitin ligase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 6
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554862,197,467 - 2,201,256 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554862,197,296 - 2,205,947 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fbxo6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554862,197,467 - 2,201,256 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554862,197,296 - 2,205,947 (-)NCBIChiLan1.0ChiLan1.0
FBXO6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,664,200 - 11,674,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl111,664,200 - 11,674,354 (+)EnsemblGRCh38hg38GRCh38
GRCh37111,724,257 - 11,734,411 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,646,768 - 11,656,998 (+)NCBINCBI36Build 36hg18NCBI36
Build 34111,658,446 - 11,668,673NCBI
Celera110,836,207 - 10,846,475 (+)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef110,878,308 - 10,888,516 (+)NCBIHuRef
CHM1_1111,712,136 - 11,722,413 (+)NCBICHM1_1
T2T-CHM13v2.0111,208,255 - 11,218,422 (+)NCBIT2T-CHM13v2.0
Fbxo6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394148,230,173 - 148,236,592 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4148,230,173 - 148,236,597 (-)EnsemblGRCm39 Ensembl
GRCm384148,145,716 - 148,152,135 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4148,145,716 - 148,152,140 (-)EnsemblGRCm38mm10GRCm38
MGSCv374147,519,825 - 147,526,244 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364146,989,587 - 146,995,624 (-)NCBIMGSCv36mm8
Celera4150,407,047 - 150,413,479 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.67NCBI
Fbxo6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85163,859,909 - 163,865,693 (-)NCBIGRCr8
mRatBN7.25158,576,729 - 158,582,520 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5158,576,759 - 158,582,525 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5161,293,652 - 161,297,063 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05163,115,443 - 163,118,858 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05163,071,790 - 163,075,208 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05164,956,285 - 164,962,075 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,956,280 - 164,959,851 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05168,614,323 - 168,620,072 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,223,009 - 165,226,420 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15165,233,196 - 165,236,608 (-)NCBI
Celera5156,856,162 - 156,859,573 (-)NCBICelera
Cytogenetic Map5q36NCBI
FBXO6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1284,549,519 - 84,554,176 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl284,549,560 - 84,580,756 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,081,851 - 81,088,009 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0285,212,668 - 85,218,810 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl285,212,675 - 85,218,790 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1281,961,418 - 81,967,576 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0282,962,035 - 82,968,196 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0284,024,909 - 84,031,072 (-)NCBIUU_Cfam_GSD_1.0
Fbxo6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505834,707,679 - 34,713,814 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936474533,254 - 542,907 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936474531,873 - 538,596 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl671,768,498 - 71,774,243 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1671,755,335 - 71,774,264 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2665,674,308 - 65,693,217 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120120,116,125 - 120,127,025 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20120,116,169 - 120,126,920 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605423,984,628 - 23,995,338 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248181,286,820 - 1,292,755 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248181,286,819 - 1,292,565 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000006516   ⟹   ENSCLAP00000006410
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554862,197,467 - 2,201,256 (-)Ensembl
RefSeq Acc Id: XM_005403997   ⟹   XP_005404054
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554862,197,296 - 2,203,835 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005403998   ⟹   XP_005404055
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554862,197,296 - 2,203,076 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005403999   ⟹   XP_005404056
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554862,197,296 - 2,204,031 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504313   ⟹   XP_013359767
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554862,197,296 - 2,205,947 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504314   ⟹   XP_013359768
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554862,197,296 - 2,203,076 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005404056   ⟸   XM_005403999
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UWE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005404054   ⟸   XM_005403997
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UWE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005404055   ⟸   XM_005403998
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013359767   ⟸   XM_013504313
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UWE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013359768   ⟸   XM_013504314
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSCLAP00000006410   ⟸   ENSCLAT00000006516
Protein Domains
F-box   FBA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004528 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006516 ENTREZGENE
  ENSCLAT00000006516.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
InterPro F-box-assoc_dom UniProtKB/TrEMBL
  F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  F-box_only UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
NCBI Gene Fbxo6 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 6 UniProtKB/TrEMBL
  PTHR12125 UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
  FBA UniProtKB/TrEMBL
PROSITE FBA UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
SMART FBA UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
Superfamily-SCOP SSF49785 UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A8C2UWE3 ENTREZGENE, UniProtKB/TrEMBL