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Gene: Fbxo6 (F-box protein 6) Mus musculus
Symbol: Fbxo6
Name: F-box protein 6
Description: Exhibits carbohydrate binding activity. Contributes to ubiquitin protein ligase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; glycoprotein catabolic process; and ubiquitin-dependent ERAD pathway. Localizes to the SCF ubiquitin ligase complex and endoplasmic reticulum quality control compartment. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; liver; and lung. Orthologous to human FBXO6 (F-box protein 6); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408845; F-box only protein 6; F-box only protein 6b; F-box protein that recognizes sugar chains 2; F-box/G-domain protein 2; FBG2; Fbs2; Fbx6b; Fbxo6b
Homo sapiens (human) : FBXO6 (F-box protein 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxo6 (F-box protein 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo6 (F-box protein 6)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO6 (F-box protein 6)
Canis lupus familiaris (dog) : FBXO6 (F-box protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo6 (F-box protein 6)
Sus scrofa (pig) : FBXO6 (F-box protein 6)
Chlorocebus sabaeus (African green monkey) : FBXO6 (F-box protein 6)
Heterocephalus glaber (naked mole-rat) : Fbxo6 (F-box protein 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl4148,145,716 - 148,152,140 (-)EnsemblGRCm38mm10GRCm38
GRCm384148,145,716 - 148,152,135 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374147,519,825 - 147,526,244 (-)NCBIGRCm37mm9NCBIm37
MGSCv364146,989,587 - 146,995,624 (-)NCBImm8
Celera4150,407,047 - 150,413,479 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fbxo6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732299
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.