Purb (purine rich element binding protein B) - Rat Genome Database

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Gene: Purb (purine rich element binding protein B) Chinchilla lanigera
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Symbol: Purb
Name: purine rich element binding protein B
RGD ID: 8836794
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: purine-rich element binding protein B; transcriptional activator protein Pur-beta
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554567,322,973 - 7,323,529 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PurbChinchillapleomorphic xanthoastrocytoma  ISORGD:13535658554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PurbChinchillanegative regulation of DNA-templated transcription acts_upstream_of_or_withinISORGD:15573609068941 PMID:15282343MGIPMID:15282343
PurbChinchillanegative regulation of transcription by RNA polymerase II involved_inISORGD:15594659068941PMID:12933792HGNC-UCLPMID:12933792|REF_RGD_ID:1581942
PurbChinchillanegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISOMGI:37052679068941 PMID:23723417MGIPMID:23723417
PurbChinchillanegative regulation of transcription by RNA polymerase II involved_inISORGD:15573609068941 PMID:15282343NTNU_SBPMID:15282343
PurbChinchillapositive regulation of transcription by RNA polymerase II involved_inISORGD:15573609068941 PMID:31918924UniProtPMID:31918924

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PurbChinchillanucleoplasm located_inISORGD:13535659068941 HPAGO_REF:0000052
PurbChinchillanucleus is_active_inISORGD:15594659068941PMID:12933792HGNC-UCLPMID:12933792|REF_RGD_ID:1581942
PurbChinchillanucleus located_inISORGD:15573609068941 PMID:15282343, PMID:33743134UniProtPMID:15282343|PMID:33743134

Molecular Function
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PurbChinchillaDNA-binding transcription factor activity enablesISORGD:15573609068941 PMID:15282343MGIPMID:15282343
PurbChinchillaDNA-binding transcription factor binding enablesISOUniProtKB:P426699068941 PMID:10318844UniProtPMID:10318844
PurbChinchillaDNA-binding transcription repressor activity, RNA polymerase II-specific enablesISORGD:15594659068941PMID:12933792HGNC-UCLPMID:12933792|REF_RGD_ID:1581942
PurbChinchillaDNA-binding transcription repressor activity, RNA polymerase II-specific enablesISORGD:15573609068941 PMID:27064749UniProtPMID:27064749
PurbChinchillaDNA-binding transcription repressor activity, RNA polymerase II-specific enablesISORGD:15573609068941 PMID:15282343, PMID:33743134NTNU_SBPMID:15282343|PMID:33743134
PurbChinchilladouble-stranded DNA binding enablesISORGD:15573609068941 PMID:15282343MGIPMID:15282343
PurbChinchillamRNA binding enablesISORGD:15573609068941 PMID:12933792UniProtPMID:12933792
PurbChinchillamRNA regulatory element binding translation repressor activity enablesISORGD:15594659068941PMID:12933792HGNC-UCLPMID:12933792|REF_RGD_ID:1581942
PurbChinchillaprotein binding enablesISOUniProtKB:Q6ZNH5|UniProtKB:Q8TBB1|UniProtKB:Q96AH0|UniProtKB:Q9BXS5|UniProtKB:Q9UBB5|UniProtKB:Q9Y5E99068941 PMID:32296183IntActPMID:32296183
PurbChinchillaprotein binding enablesISOUniProtKB:Q8VIM5|UniProtKB:Q9JM739068941 PMID:33743134UniProtPMID:33743134
PurbChinchillaprotein binding enablesISOUniProtKB:P629609068941 PMID:27064749UniProtPMID:27064749
PurbChinchillaprotein binding enablesISOPR:O89090|PR:P97471|PR:Q62432|PR:Q8BUN59068941 PMID:15282343MGIPMID:15282343
PurbChinchillapurine-rich negative regulatory element binding enablesISORGD:15594659068941PMID:12933792HGNC-UCLPMID:12933792|REF_RGD_ID:1581942
PurbChinchillaRNA binding enablesISORGD:15573609068941 PMID:23723417MGIPMID:23723417
PurbChinchillaRNA polymerase II transcription regulatory region sequence-specific DNA binding enablesISORGD:15573609068941 PMID:15282343NTNU_SBPMID:15282343
PurbChinchillasingle-stranded DNA binding enablesISORGD:15573609068941 PMID:10318844, PMID:12933792UniProtPMID:10318844|PMID:12933792
PurbChinchillaSMAD binding enablesISORGD:15573609068941 PMID:15282343MGIPMID:15282343
1 to 17 of 17 rows


#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:22301074   PMID:30032202  



Purb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554567,322,973 - 7,323,529 (+)NCBIChiLan1.0ChiLan1.0
PURB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,876,299 - 44,885,530 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,876,299 - 44,885,530 (-)EnsemblGRCh38hg38GRCh38
GRCh37744,915,898 - 44,925,129 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,882,417 - 44,891,485 (-)NCBINCBI36Build 36hg18NCBI36
Build 34744,689,133 - 44,698,200NCBI
Celera745,014,669 - 45,023,741 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef744,801,230 - 44,810,302 (-)NCBIHuRef
CHM1_1744,920,237 - 44,929,309 (-)NCBICHM1_1
T2T-CHM13v2.0745,036,709 - 45,045,943 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,955,325 - 44,964,397 (-)NCBI
Purb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39116,417,599 - 6,426,076 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl116,417,599 - 6,425,917 (-)EnsemblGRCm39 Ensembl
GRCm38116,467,599 - 6,476,076 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl116,467,599 - 6,475,917 (-)EnsemblGRCm38mm10GRCm38
MGSCv37116,374,776 - 6,375,920 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36116,374,776 - 6,375,920 (-)NCBIMGSCv36mm8
Celera116,960,150 - 6,961,293 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.16NCBI
Purb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,556,296 - 85,558,779 (-)NCBIGRCr8
mRatBN7.21481,342,374 - 81,344,857 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,336,448 - 81,351,432 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,743,668 - 85,746,151 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,983,466 - 86,985,949 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01483,433,062 - 83,435,545 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,736,876 - 86,739,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,736,878 - 86,739,335 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01480,371,417 - 80,373,876 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,230,346 - 87,232,805 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1480,223,695 - 80,226,154 (-)NCBICelera
Cytogenetic Map14q21NCBI
PURB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,789,512 - 49,802,328 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1798,114,250 - 98,127,055 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0745,590,183 - 45,600,089 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1745,659,121 - 45,673,991 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl745,667,233 - 45,668,159 (-)Ensemblpanpan1.1panPan2
PURB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,512,329 - 2,520,763 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,340,299 - 14,348,729 (+)NCBIROS_Cfam_1.0
UNSW_CanFamBas_1.01613,973,590 - 13,982,018 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01613,952,878 - 13,961,316 (+)NCBIUU_Cfam_GSD_1.0
Purb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118100,526,521 - 100,551,530 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647819,738,252 - 19,747,345 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PURB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,510,182 - 50,511,108 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11850,510,010 - 50,518,965 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,333,599 - 55,342,149 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PURB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12113,796,087 - 13,805,162 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2113,796,118 - 13,797,056 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660628,731,839 - 8,741,238 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Purb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,398,481 - 7,399,434 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,398,481 - 7,406,923 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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RefSeq Transcripts XM_013520514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01046407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDJ01139895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_013520514   ⟹   XP_013375968
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554567,322,973 - 7,323,529 (+)NCBI
Sequence:
Protein RefSeqs XP_013375968 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_013375968   ⟸   XM_013520514
- Sequence:



Database
Acc Id
Source(s)
NCBI Gene LOC102008380 ENTREZGENE


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Purb  purine rich element binding protein B    purine-rich element binding protein B  Symbol and/or name change 5135510 APPROVED
2015-08-25 Purb  purine-rich element binding protein B  LOC102008380  uncharacterized LOC102008380  Symbol and/or name change 5135510 APPROVED