Pdgfd (platelet derived growth factor D) - Rat Genome Database

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Gene: Pdgfd (platelet derived growth factor D) Chinchilla lanigera
Analyze
Symbol: Pdgfd
Name: platelet derived growth factor D
RGD ID: 8834072
Description: INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; ASSOCIATED WITH ataxia telangiectasia (ortholog); atherosclerosis (ortholog); Bone Metastasis (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: platelet-derived growth factor D
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554126,866,869 - 7,093,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554126,868,995 - 7,093,353 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PdgfdChinchillaatherosclerosis  ISOPDGFD (Homo sapiens)9068941associated with methylation and coronary artery disease:mRNA:altered expression:artery wall (human)RGDPMID:33381146 and REF_RGD_ID:155882464
PdgfdChinchillaBone Metastasis  ISOPDGFD (Homo sapiens)9068941associated with prostate carcinomaRGDPMID:22158043 and REF_RGD_ID:13506772
PdgfdChinchillaCardiac Allograft Vasculopathy  ISOPDGFD (Homo sapiens)9068941 RGDPMID:19213942 and REF_RGD_ID:9854642
PdgfdChinchillaCarotid Artery Injuries  ISOPdgfd (Rattus norvegicus)9068941protein:increased expression:carotid artery:RGDPMID:18258854 and REF_RGD_ID:9854624
PdgfdChinchillaCOVID-19  ISOPDGFD (Homo sapiens)9068941mRNA:decreased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
PdgfdChinchillaglomerulonephritis  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:21866094 and REF_RGD_ID:9854633
PdgfdChinchillaIntimal Hyperplasia  ISOPdgfd (Rattus norvegicus)9068941protein:increased expression:smooth muscle cell:RGDPMID:15752751 and REF_RGD_ID:9854640
PdgfdChinchillaliver cirrhosis  ISOPdgfd (Rattus norvegicus)9068941mRNA and protein:increased expression:liver:RGDPMID:17397961 and REF_RGD_ID:9854631
PdgfdChinchillamesangial proliferative glomerulonephritis treatmentISOPdgfd (Rattus norvegicus)9068941 RGDPMID:17308324 and REF_RGD_ID:9854629
PdgfdChinchillamesangial proliferative glomerulonephritis  ISOPdgfd (Rattus norvegicus)9068941mRNA more ...RGDPMID:12937299 and REF_RGD_ID:9854637
PdgfdChinchillamyocardial infarction  ISOPdgfd (Rattus norvegicus)9068941mRNA and protein:altered expression:myocardium:RGDPMID:21767547 and REF_RGD_ID:9854703
PdgfdChinchillaprostate carcinoma disease_progressionISOPDGFD (Homo sapiens)9068941 RGDPMID:21098708 and REF_RGD_ID:13506773
PdgfdChinchillaprostatic hypertrophy disease_progressionISOPDGFD (Homo sapiens)9068941 RGDPMID:22689130 and REF_RGD_ID:13506770
PdgfdChinchillaTransplant Rejection  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:19213942 and REF_RGD_ID:9854642
1 to 14 of 14 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PdgfdChinchillaataxia telangiectasia  ISOPDGFD (Homo sapiens)8554872ClinVar Annotator: match by term: Ataxia-telangiectasia syndromeClinVarPMID:23807571 more ...
PdgfdChinchillaintellectual disability  ISOPDGFD (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
PdgfdChinchillaprimary ovarian insufficiency  ISOPDGFD (Homo sapiens)8554872ClinVar Annotator: match by term: Premature ovarian insufficiencyClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PdgfdChinchillacoronary artery disease  ISOPDGFD (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21378988 and PMID:34961328
PdgfdChinchillaFibrosis  ISOPDGFD (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25280005
PdgfdChinchillaLung Injury  ISOPDGFD (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25280005


Biological Process
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PdgfdChinchillacellular response to amino acid stimulus acts_upstream_of_or_withinISOPdgfd (Mus musculus)9068941 PMID:20548288MGIPMID:20548288
PdgfdChinchillacellular response to hydrogen peroxide  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:16189269 and REF_RGD_ID:9854628
PdgfdChinchillacellular response to platelet-derived growth factor stimulus  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:16039137 and REF_RGD_ID:1581755
PdgfdChinchillacellular response to transforming growth factor beta stimulus  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:23585135 and REF_RGD_ID:9854632
PdgfdChinchillapositive regulation of fibroblast proliferation  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:21866094 and REF_RGD_ID:9854633
PdgfdChinchillapositive regulation of glomerular mesangial cell proliferation  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:12937299 and REF_RGD_ID:9854637
PdgfdChinchillapositive regulation of monocyte extravasation  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:12937299 and REF_RGD_ID:9854637
PdgfdChinchillapositive regulation of smooth muscle cell chemotaxis  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:15752751 and REF_RGD_ID:9854640
PdgfdChinchillapositive regulation of smooth muscle cell proliferation  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:15752751 and REF_RGD_ID:9854640
PdgfdChinchillaregulation of peptidyl-tyrosine phosphorylation acts_upstream_of_or_withinISOPdgfd (Mus musculus)9068941 PMID:11940581MGIPMID:11940581
1 to 10 of 10 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PdgfdChinchillaextracellular space  ISOPdgfd (Rattus norvegicus)9068941 RGDPMID:17397961 and REF_RGD_ID:9854631

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PdgfdChinchillaplatelet-derived growth factor signaling pathway  ISOPDGFD (Homo sapiens)9068941 PIDPID:200201

#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:22301074   PMID:30032202  



Pdgfd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554126,866,869 - 7,093,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554126,868,995 - 7,093,353 (-)NCBIChiLan1.0ChiLan1.0
PDGFD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811103,907,189 - 104,164,147 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11103,907,189 - 104,164,379 (-)EnsemblGRCh38hg38GRCh38
GRCh3711103,777,917 - 104,034,875 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611103,283,124 - 103,540,237 (-)NCBINCBI36Build 36hg18NCBI36
Celera11100,938,918 - 101,198,288 (-)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef1199,706,933 - 99,964,618 (-)NCBIHuRef
CHM1_111103,660,854 - 103,917,997 (-)NCBICHM1_1
T2T-CHM13v2.011103,910,709 - 104,168,067 (-)NCBIT2T-CHM13v2.0
Pdgfd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3996,168,377 - 6,534,284 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl96,168,584 - 6,378,850 (+)EnsemblGRCm39 Ensembl
GRCm3896,168,363 - 6,534,284 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl96,168,584 - 6,378,850 (+)EnsemblGRCm38mm10GRCm38
MGSCv3796,168,612 - 6,377,519 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3696,168,612 - 6,377,519 (+)NCBIMGSCv36mm8
Celera93,573,881 - 3,783,053 (+)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
Pdgfd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8811,773,335 - 12,007,277 (+)NCBIGRCr8
mRatBN7.283,488,448 - 3,722,395 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl83,488,423 - 3,722,395 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx87,456,757 - 7,689,644 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.085,754,534 - 5,987,421 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.083,748,256 - 3,982,028 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.084,441,010 - 4,666,754 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl84,440,876 - 4,669,014 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.084,454,510 - 4,682,165 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.483,326,218 - 3,341,300 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.183,125,520 - 3,341,300 (+)NCBI
Celera85,067,751 - 5,287,344 (+)NCBICelera
Cytogenetic Map8q11NCBI
PDGFD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29104,705,685 - 104,963,328 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111105,795,250 - 106,051,391 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01198,852,652 - 99,110,147 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111102,337,099 - 102,593,741 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11102,357,079 - 102,593,273 (-)Ensemblpanpan1.1panPan2
PDGFD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1527,863,739 - 28,092,376 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl527,863,591 - 28,089,936 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha527,797,064 - 28,031,427 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0527,910,756 - 28,139,449 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl527,910,863 - 28,139,447 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1527,944,599 - 28,172,420 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0527,831,224 - 28,058,908 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0528,005,540 - 28,233,502 (+)NCBIUU_Cfam_GSD_1.0
Pdgfd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494787,338,657 - 87,562,388 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365513,974,104 - 4,198,927 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365513,974,140 - 4,197,852 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDGFD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl934,388,643 - 34,621,244 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1934,388,636 - 34,621,227 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2938,432,144 - 38,616,298 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDGFD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,293,263 - 95,551,138 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl195,292,193 - 95,385,199 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604330,343,471 - 30,592,345 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdgfd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249181,052,567 - 1,293,192 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249181,052,640 - 1,293,138 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Ensembl Acc Id: ENSCLAT00000020085   ⟹   ENSCLAP00000019892
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554126,866,869 - 7,093,998 (-)Ensembl
RefSeq Acc Id: XM_005377998   ⟹   XP_005378055
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554126,868,995 - 7,093,353 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005377999   ⟹   XP_005378056
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554126,868,995 - 7,093,353 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013511230   ⟹   XP_013366684
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554126,868,995 - 7,093,353 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013511231   ⟹   XP_013366685
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554126,868,995 - 7,093,353 (-)NCBI
Sequence:
Protein RefSeqs XP_005378055 (Get FASTA)   NCBI Sequence Viewer  
  XP_005378056 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366684 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366685 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000019892
  ENSCLAP00000019892.1
RefSeq Acc Id: XP_005378056   ⟸   XM_005377999
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005378055   ⟸   XM_005377998
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VZS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366685   ⟸   XM_013511231
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013366684   ⟸   XM_013511230
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSCLAP00000019892   ⟸   ENSCLAT00000020085


1 to 21 of 21 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000013637 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020085 ENTREZGENE
  ENSCLAT00000020085.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
  2.60.120.290 UniProtKB/TrEMBL
InterPro CUB_dom UniProtKB/TrEMBL
  Cystine-knot_cytokine UniProtKB/TrEMBL
  PDGF/VEGF_dom UniProtKB/TrEMBL
  Sperma_CUB_dom_sf UniProtKB/TrEMBL
NCBI Gene Pdgfd ENTREZGENE
PANTHER PLATELET-DERIVED GROWTH FACTOR UniProtKB/TrEMBL
  PTHR11633:SF4 UniProtKB/TrEMBL
Pfam CUB UniProtKB/TrEMBL
  PDGF UniProtKB/TrEMBL
PROSITE CUB UniProtKB/TrEMBL
  PDGF_2 UniProtKB/TrEMBL
SMART CUB UniProtKB/TrEMBL
  PDGF UniProtKB/TrEMBL
Superfamily-SCOP SSF49854 UniProtKB/TrEMBL
  SSF57501 UniProtKB/TrEMBL
UniProt A0A8C2VZS8 ENTREZGENE, UniProtKB/TrEMBL
1 to 21 of 21 rows