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Gene: Pdgfd (platelet derived growth factor D) Ictidomys tridecemlineatus

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Symbol:

Pdgfd

Name:

platelet derived growth factor D

RGD ID:

12528629

Description:

ENCODES a protein that exhibits growth factor activity (inferred); growth factor receptor binding (inferred); platelet-derived growth factor receptor binding (inferred); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); cellular response to transforming growth factor beta stimulus (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; ASSOCIATED WITH ataxia telangiectasia (ortholog); atherosclerosis (ortholog); Bone Metastasis (ortholog); FOUND IN extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

platelet derived growth factor D, transcript variant X1; platelet derived growth factor D, transcript variant X2; platelet-derived growth factor D

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	87,338,657 - 87,562,388 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936551	3,974,104 - 4,198,927 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936551	3,974,140 - 4,197,852 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pdgfd	Squirrel	atherosclerosis		ISO	PDGFD (Homo sapiens)	9068941	associated with methylation and coronary artery disease:mRNA:altered expression:artery wall (human)	RGD	PMID:33381146 and REF_RGD_ID:155882464
Pdgfd	Squirrel	Bone Metastasis		ISO	PDGFD (Homo sapiens)	9068941	associated with prostate carcinoma	RGD	PMID:22158043 and REF_RGD_ID:13506772
Pdgfd	Squirrel	Cardiac Allograft Vasculopathy		ISO	PDGFD (Homo sapiens)	9068941		RGD	PMID:19213942 and REF_RGD_ID:9854642
Pdgfd	Squirrel	Carotid Artery Injuries		ISO	Pdgfd (Rattus norvegicus)	9068941	protein:increased expression:carotid artery:	RGD	PMID:18258854 and REF_RGD_ID:9854624
Pdgfd	Squirrel	COVID-19		ISO	PDGFD (Homo sapiens)	9068941	mRNA:decreased expression:peripheral blood mononuclear cell (human)	RGD	PMID:32228226 and REF_RGD_ID:28912744
Pdgfd	Squirrel	glomerulonephritis		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:21866094 and REF_RGD_ID:9854633
Pdgfd	Squirrel	Intimal Hyperplasia		ISO	Pdgfd (Rattus norvegicus)	9068941	protein:increased expression:smooth muscle cell:	RGD	PMID:15752751 and REF_RGD_ID:9854640
Pdgfd	Squirrel	liver cirrhosis		ISO	Pdgfd (Rattus norvegicus)	9068941	mRNA and protein:increased expression:liver:	RGD	PMID:17397961 and REF_RGD_ID:9854631
Pdgfd	Squirrel	mesangial proliferative glomerulonephritis		ISO	Pdgfd (Rattus norvegicus)	9068941	mRNA more ...	RGD	PMID:12937299 and REF_RGD_ID:9854637
Pdgfd	Squirrel	mesangial proliferative glomerulonephritis	treatment	ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:17308324 and REF_RGD_ID:9854629
Pdgfd	Squirrel	myocardial infarction		ISO	Pdgfd (Rattus norvegicus)	9068941	mRNA and protein:altered expression:myocardium:	RGD	PMID:21767547 and REF_RGD_ID:9854703
Pdgfd	Squirrel	prostate carcinoma	disease_progression	ISO	PDGFD (Homo sapiens)	9068941		RGD	PMID:21098708 and REF_RGD_ID:13506773
Pdgfd	Squirrel	prostatic hypertrophy	disease_progression	ISO	PDGFD (Homo sapiens)	9068941		RGD	PMID:22689130 and REF_RGD_ID:13506770
Pdgfd	Squirrel	Transplant Rejection		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:19213942 and REF_RGD_ID:9854642

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pdgfd	Squirrel	ataxia telangiectasia		ISO	PDGFD (Homo sapiens)	8554872	ClinVar Annotator: match by term: Ataxia-telangiectasia syndrome	ClinVar	PMID:23807571 more ...
Pdgfd	Squirrel	intellectual disability		ISO	PDGFD (Homo sapiens)	8554872	ClinVar Annotator: match by term: Intellectual disability	ClinVar
Pdgfd	Squirrel	primary ovarian insufficiency		ISO	PDGFD (Homo sapiens)	8554872	ClinVar Annotator: match by term: Premature ovarian insufficiency	ClinVar	PMID:25741868

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pdgfd	Squirrel	coronary artery disease		ISO	PDGFD (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21378988 and PMID:34961328
Pdgfd	Squirrel	Fibrosis		ISO	PDGFD (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25280005
Pdgfd	Squirrel	Lung Injury		ISO	PDGFD (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25280005

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pdgfd	Squirrel	cellular response to amino acid stimulus	acts_upstream_of_or_within	IEA	UniProtKB:Q925I7 and ensembl:ENSMUSP00000128388	150520179		Ensembl	GO_REF:0000107
Pdgfd	Squirrel	cellular response to hydrogen peroxide		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:16189269 and REF_RGD_ID:9854628
Pdgfd	Squirrel	cellular response to platelet-derived growth factor stimulus		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:16039137 and REF_RGD_ID:1581755
Pdgfd	Squirrel	cellular response to transforming growth factor beta stimulus		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:23585135 and REF_RGD_ID:9854632
Pdgfd	Squirrel	platelet-derived growth factor receptor signaling pathway	involved_in	IEA	PANTHER:PTN000014309	150520179		TreeGrafter	GO_REF:0000118
Pdgfd	Squirrel	positive regulation of cell division	involved_in	IEA	UniProtKB-KW:KW-0497	150520179		UniProt	GO_REF:0000043
Pdgfd	Squirrel	positive regulation of cell migration	involved_in	IEA	PANTHER:PTN000014309	150520179		TreeGrafter	GO_REF:0000118
Pdgfd	Squirrel	positive regulation of cell population proliferation	involved_in	IEA	PANTHER:PTN000014309	150520179		TreeGrafter	GO_REF:0000118
Pdgfd	Squirrel	positive regulation of ERK1 and ERK2 cascade	involved_in	IEA	PANTHER:PTN000014309	150520179		TreeGrafter	GO_REF:0000118
Pdgfd	Squirrel	positive regulation of fibroblast proliferation		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:21866094 and REF_RGD_ID:9854633
Pdgfd	Squirrel	positive regulation of glomerular mesangial cell proliferation		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:12937299 and REF_RGD_ID:9854637
Pdgfd	Squirrel	positive regulation of monocyte extravasation		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:12937299 and REF_RGD_ID:9854637
Pdgfd	Squirrel	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	involved_in	IEA	PANTHER:PTN000014309	150520179		TreeGrafter	GO_REF:0000118
Pdgfd	Squirrel	positive regulation of smooth muscle cell chemotaxis		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:15752751 and REF_RGD_ID:9854640
Pdgfd	Squirrel	positive regulation of smooth muscle cell proliferation		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:15752751 and REF_RGD_ID:9854640
Pdgfd	Squirrel	regulation of peptidyl-tyrosine phosphorylation	acts_upstream_of_or_within	ISO	Pdgfd (Mus musculus)	9068941	PMID:11940581	MGI	PMID:11940581

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pdgfd	Squirrel	extracellular region	located_in	IEA	UniProtKB-KW:KW-0964	150520179		UniProt	GO_REF:0000043
Pdgfd	Squirrel	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	150520179		UniProt	GO_REF:0000044
Pdgfd	Squirrel	extracellular space		ISO	Pdgfd (Rattus norvegicus)	9068941		RGD	PMID:17397961 and REF_RGD_ID:9854631
Pdgfd	Squirrel	extracellular space	located_in	IEA	PANTHER:PTN000014309	150520179		TreeGrafter	GO_REF:0000118
Pdgfd	Squirrel	membrane	located_in	IEA	InterPro:IPR000072	150520179		InterPro	GO_REF:0000002

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pdgfd	Squirrel	growth factor activity	enables	IEA	InterPro:IPR000072	150520179		InterPro	GO_REF:0000002
Pdgfd	Squirrel	growth factor activity	enables	IEA	UniProtKB-KW:KW-0339	150520179		UniProt	GO_REF:0000043
Pdgfd	Squirrel	growth factor receptor binding	enables	IEA	PANTHER:PTN000014309	150520179		TreeGrafter	GO_REF:0000118
Pdgfd	Squirrel	platelet-derived growth factor receptor binding	enables	IEA	PANTHER:PTN000014309	150520179		TreeGrafter	GO_REF:0000118

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pdgfd	Squirrel	platelet-derived growth factor signaling pathway		ISO	PDGFD (Homo sapiens)	9068941		PID	PID:200201

PMID:22301074	PMID:30032202

Pdgfd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	87,338,657 - 87,562,388 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936551	3,974,104 - 4,198,927 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936551	3,974,140 - 4,197,852 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PDGFD
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	103,907,189 - 104,164,147 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	103,907,189 - 104,164,379 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	103,777,917 - 104,034,875 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	103,283,124 - 103,540,237 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	100,938,918 - 101,198,288 (-)	NCBI		Celera
Cytogenetic Map	11	q22.3	NCBI
HuRef	11	99,706,933 - 99,964,618 (-)	NCBI		HuRef
CHM1_1	11	103,660,854 - 103,917,997 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	103,910,709 - 104,168,067 (-)	NCBI		T2T-CHM13v2.0

Pdgfd
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	6,168,377 - 6,534,284 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	6,168,584 - 6,378,850 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	6,168,363 - 6,534,284 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	6,168,584 - 6,378,850 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	6,168,612 - 6,377,519 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	6,168,612 - 6,377,519 (+)	NCBI		MGSCv36	mm8
Celera	9	3,573,881 - 3,783,053 (+)	NCBI		Celera
Cytogenetic Map	9	A1	NCBI
cM Map	9	2.46	NCBI

Pdgfd
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	11,773,335 - 12,007,277 (+)	NCBI		GRCr8
mRatBN7.2	8	3,488,448 - 3,722,395 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	3,488,423 - 3,722,395 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	7,456,757 - 7,689,644 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	5,754,534 - 5,987,421 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	3,748,256 - 3,982,028 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	4,441,010 - 4,666,754 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	4,440,876 - 4,669,014 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	4,454,510 - 4,682,165 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	3,326,218 - 3,341,300 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	3,125,520 - 3,341,300 (+)	NCBI
Celera	8	5,067,751 - 5,287,344 (+)	NCBI		Celera
Cytogenetic Map	8	q11	NCBI

Pdgfd
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	6,866,869 - 7,093,998 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	6,868,995 - 7,093,353 (-)	NCBI	ChiLan1.0	ChiLan1.0

PDGFD
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	104,705,685 - 104,963,328 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	105,795,250 - 106,051,391 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	98,852,652 - 99,110,147 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	102,337,099 - 102,593,741 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	102,357,079 - 102,593,273 (-)	Ensembl	panpan1.1		panPan2

PDGFD
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	27,863,739 - 28,092,376 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	27,863,591 - 28,089,936 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	27,797,064 - 28,031,427 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	27,910,756 - 28,139,449 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	27,910,863 - 28,139,447 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	27,944,599 - 28,172,420 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	27,831,224 - 28,058,908 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	28,005,540 - 28,233,502 (+)	NCBI		UU_Cfam_GSD_1.0

PDGFD
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	34,388,643 - 34,621,244 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	34,388,636 - 34,621,227 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	38,432,144 - 38,616,298 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PDGFD
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	95,293,263 - 95,551,138 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	95,292,193 - 95,385,199 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	30,343,471 - 30,592,345 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pdgfd
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624918	1,052,567 - 1,293,192 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624918	1,052,640 - 1,293,138 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005329087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005329088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040285144	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000004225 ⟹ ENSSTOP00000003794

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936551	3,974,104 - 4,198,927 (+)	Ensembl

RefSeq Acc Id:

XM_005329087 ⟹ XP_005329144

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	87,338,657 - 87,562,386 (-)	NCBI
SpeTri2.0	NW_004936551	3,974,141 - 4,197,852 (+)	NCBI

Sequence:

show sequence

GCCGCCGCTTTGAGCTGTGTGCGCGCAGCTCAGGGGGCGCTGCCACCCAGGCCGGGCCGGACAAGGCGCCGCCTGCCCCCTGCAGCTTGTGCTGCTGCTGCCGGCCACAGGAGGGGGCGAACAAACGT
CAACCTGTTGTTTGTCCAGTCACCCTTTATCAACTCTCAGCACCACAAGGAAGTGCGGCACCCACACGCGCTCAGAAAGTTCAGCGTGCAGGAAGTTTAGGGAGAGCTCGGCGATTAGCTCAGCGGGC
CGGGCCAGCGCTGGGGAGCGCAGGCGGCAAGAGCGCAGGGAGGCGCGGCGTCCGTCCCGAGCAGAACCCGGTTTTTGTCTTGGAGCGAAGGTGTCCCGAAGTCCCTAATCCCAAATGCACCGGCTCAT
CTTCGTCTACACCCTGGCCTGCGCAAACTTCTGCAGCTTTCGGGACACTTATGCAACTCCGCAAAGCGCATCCATCAAAGCTTTGCGCAACGCCAACCTCAGGAGAGATGAGAGCAATCACCTCACAG
ACTTGTACCGAAAAGAAGAAACTATCCAAGTGACAGGAAACGGTCATGTACAGAGTCCACGCTTCCCGAATAGCTACCCCAGGAACCTGCTTCTGACATGGCGGCTCCATTCCCAAGACAAAACCAGG
ATACAGCTGGCATTTGACAATCAATTTGGATTAGAGGAAGCAGAAAATGATATCTGTAGGTACGATTTTGTGGAAGTTGAAGATGTATCTGAAACCAGTACCGTTATTAGAGGCCGATGGTGTGGACA
CAAGGAAGTTCCTCCAAGAATAACATCAAGAACAAACCAAATTAAAATAACATTCAAGTCTGATGACTACTTTGTGGCAAAACCTGGATTCAGGATTTATTATTCTTTTGTGAAAGATTTCCAACCTG
CAGAAGCCTCAGACACCAACTGGGAATCGGTCACAAGTTCGAACTCGGGGGTATCTTATCGCTCTTCATCTGTAACGGACTCTGCTCTTACTGTGGAGGCTTTGGACAAAAAAGTTGCAGAATTTGAT
ACTGTGGAAGATCTGCTCAAGCACTTTAATCCAGAGTCATGGCAAGATGATCTTGAGAATTTGTATTTGGACACTCCTCATTATCGAGGCAGATCATACCATGAACGGAAATCAAAAGTTGACCTGGA
CAGGCTCAACGATGATGTCAAGCGTTACAGTTGCACTCCCAGGAATTACTCAGTCAATTTAAGACAGGAGCTGCAGTTGACCAACGCGGTCTTCTTTCCACGTTGCCTCCTCGTGCAGCGCTGTGGAG
GAAATTGTGGCTGTGGAACTGCCAACTCGAAGTCCTGCAGGTGCAATTCAGGGAAAACTGTGAAAAAGTATCATGAGGTACTGAAGTTTGAACCTGGCAATATCAAGAGGAGGGGCCTGGCTAAGAAC
ATGGCTCTTGTTGACATCCAATTGGATCACCATGAACGGTGTGATTGTACCTGCAGCTCCAGACCACCTCGATAAAAGAATGTGCATAAACTTATATTGAGCATGAAAGAACCTTTAGTTTAAGAAGG
ATATGGTAAGGGACCCTTTCCCCACCCCCAGCAACCGAATTTGCTACTAGCCTGAAATACAATGATACGGTCATTGCTGAGACGACCTAGCTTTGTTAGTTCTGTGGCAAGTAGAAAGGTGCATCATC
AGTTTCTATATCCAAGAATGTAAAACTGCATTTTATAGTAGTATGTGAGGATATATATGTATACACACAAATATATACATATGTCCAGGATATGTGTAAATAGATACATGGTTTATTCAGTAGGTACA
ACCAAGTACACCAGAGTTACATATGGCTGAATGATTTAGACCCTTAATATTTTTCCAAAATAAGGGTAAGGGATATGTCAAATATATAACACACATCTGTAGGAAACTCAGAAGATGAACTTTTTATT
GTGTTGAATTTTGAATCGCAAACCATTTTGGATCTTGAGCCCTTAAAGAAAGCATCTTGTATATTAAACACATATAGGCTTTTCTTAGATATCTGCCTTAATTATAAAAAAGGAAAAATATGGTTTGT
GGAAAAAAAGACAATTACCTAAGCATTTTTTTCCATGAGATGCACTACACATGCTTGGTAATGTGGACTATAGTTGCCTTTCTCCAAAATCATGCCATAATAATGTGGGAAATTTAGAAATTAAGTCT
CTAAGTTCTCTTTTTATGCATTTTCTGAGACATTCTAATTCATTTAATACCCATCTCAAAAAATATTGCTCAGAGTGTTTATCATTATGATCCTTCAAGAGACAAAATTTTAGCAGAATTTTAAATTT
TTTTCTCTGCAAAAATTCCTCCAAAATAACAAATCCTTTAATAAATGGCATGGAGATTATGTATGAACCTTTCAAATGGTGTTCATTGAAAAATTTGGGCAGATGAAAGTCAAAAACCTAAGCATTGA
AATATTGACATAACTGGAAATTAGGTGGAATCTTTGATAGGATCCATATTTAATAATGGTTTCAAACTATCCAAACTGTGCCAATAATTTTATGTATTTTGCTTTTGTGTTCCTGTCTCTTCAATATA
TACACATGGATTTACAATGGCATTTTATATTTGGAGAGCCATCATGGATTATTTATAACCTAAAAACTTTTGTATATTAATAAAGCAAGCAAATTTTATTGATGTAAATCCCTAATTATATCCTCACT
TAACATTTCTGAATTTCTATTTCTGATCCAAGTGAAATCAGATCTGGAGTCTTCTGTTCTTTCCAAATCTAGGGAGCCCCCTGTAAATTATGGGAGTATAAGTTTTGCCCTACTACACCTCTTGAAAA
CTGTTTTGCATTTGTTAATGATATTTGGAGTAAAATTTTCTCTCTGACTCCTTTGTGTCTATTTTAAAGAGACTGACTTCAGGAGTAGGAAATGATTCATCATTCTCAAAGCAAGACACTTAAGAAGG
AACACTGAGATCAACATAGCTCAAGGGTTGCTCACGGAGGACCACATTTTTCCTCCAGTCTGGAGAGTTAAAGGAGAGCTGATTTCTTTCATGAGTCCAGGGTCCTACTGACCACAACCAGTTAGTGT
GAGGGAGACGTGCCCCCACTGTCGAGGTCCTGGTGTCAGATGAATGTCCTACATATATTGGGACTTTTATGTACAGTGCTCTCAGACCCAAGTTGCCAGCTGTCCTCCAGTAGCTTATTTCTTCTTGA
CTCTTTGAAATAAGACCTACGCTTATTGATGATGGACTTTCTAAAACTCCCCTAAAAGTGTTCAGTGTTTTTACTCAGGGAATAAGTGGTGAAATAAAGCACTCTGTTATTCAGTTCTCCTAAAATCC
CAGAGCACAGTCAGAAATAGCCCAGGCAGACTAGTCATAATTAGGAGCCACTTCCCTTTCAGGACCACTTGCATAATTTTCCTGGGAAAACATCAGCTTCCTGTTCCAAAATCAAAATGTGTGTTAAC
ATCACTCACTTTAGCTTGTACAGCTCACATTGTAGCTGTGAATATGAAAAATCCTCCGTGTTCTAACCCAATTTTCAATAAACCTCCCAGGCTGCAATAACCAGGATGGTTTTCAGTTAAAGCCCTAT
CTGTACTTTTTATTTATTAGCTGAGATGTAAGCAGACGTATTCACTCACTTATCCTTTTCTTTCCTGCATGTTTATTAAAACTTCTCCCTTGGTTATCTGTTACCTATCGCACTTCCAACGTGTAGCC
AATAAATCTGTTCCATTGCCATCAAAGGAATAAAAAGTTCACTGTACAAATTACATTTCAAAACACACCCTAATAAATCCACATTGCTGCACAGCTCACTCACCTGGAATAATGCCTTTCATTCAATA
TGTTCTTATAAAGCAGAACACTTTCGTAAGTAGAATGTTTTATGTTTTTTTGTCATATCGGTAACATGCAGCTTTTTCCTCTCACAGCATTTTCTATAGCAAATGTAATATGCCTCTTATCTTCATGA
AAAATAAATATTGCTTTTGAACAAAA

hide sequence

RefSeq Acc Id:

XM_005329088 ⟹ XP_005329145

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	87,338,657 - 87,562,387 (-)	NCBI
SpeTri2.0	NW_004936551	3,974,140 - 4,197,852 (+)	NCBI

Sequence:

show sequence

CGCCGCCGCTTTGAGCTGTGTGCGCGCAGCTCAGGGGGCGCTGCCACCCAGGCCGGGCCGGACA
AGGCGCCGCCTGCCCCCTGCAGCTTGTGCTGCTGCTGCCGGCCACAGGAGGGGGCGAACAAACGTCAACCTGTTGTTTGTCCAGTCACCCTTTATCAACTCTCAGCACCACAAGGAAGTGCGGCACCC
ACACGCGCTCAGAAAGTTCAGCGTGCAGGAAGTTTAGGGAGAGCTCGGCGATTAGCTCAGCGGGCCGGGCCAGCGCTGGGGAGCGCAGGCGGCAAGAGCGCAGGGAGGCGCGGCGTCCGTCCCGAGCA
GAACCCGGTTTTTGTCTTGGAGCGAAGGTGTCCCGAAGTCCCTAATCCCAAATGCACCGGCTCATCTTCGTCTACACCCTGGCCTGCGCAAACTTCTGCAGCTTTCGGGACACTTATGCAACTCCGCA
AAGCGCATCCATCAAAGCTTTGCGCAACGCCAACCTCAGGAGAGATGACTTGTACCGAAAAGAAGAAACTATCCAAGTGACAGGAAACGGTCATGTACAGAGTCCACGCTTCCCGAATAGCTACCCCA
GGAACCTGCTTCTGACATGGCGGCTCCATTCCCAAGACAAAACCAGGATACAGCTGGCATTTGACAATCAATTTGGATTAGAGGAAGCAGAAAATGATATCTGTAGGTACGATTTTGTGGAAGTTGAA
GATGTATCTGAAACCAGTACCGTTATTAGAGGCCGATGGTGTGGACACAAGGAAGTTCCTCCAAGAATAACATCAAGAACAAACCAAATTAAAATAACATTCAAGTCTGATGACTACTTTGTGGCAAA
ACCTGGATTCAGGATTTATTATTCTTTTGTGAAAGATTTCCAACCTGCAGAAGCCTCAGACACCAACTGGGAATCGGTCACAAGTTCGAACTCGGGGGTATCTTATCGCTCTTCATCTGTAACGGACT
CTGCTCTTACTGTGGAGGCTTTGGACAAAAAAGTTGCAGAATTTGATACTGTGGAAGATCTGCTCAAGCACTTTAATCCAGAGTCATGGCAAGATGATCTTGAGAATTTGTATTTGGACACTCCTCAT
TATCGAGGCAGATCATACCATGAACGGAAATCAAAAGTTGACCTGGACAGGCTCAACGATGATGTCAAGCGTTACAGTTGCACTCCCAGGAATTACTCAGTCAATTTAAGACAGGAGCTGCAGTTGAC
CAACGCGGTCTTCTTTCCACGTTGCCTCCTCGTGCAGCGCTGTGGAGGAAATTGTGGCTGTGGAACTGCCAACTCGAAGTCCTGCAGGTGCAATTCAGGGAAAACTGTGAAAAAGTATCATGAGGTAC
TGAAGTTTGAACCTGGCAATATCAAGAGGAGGGGCCTGGCTAAGAACATGGCTCTTGTTGACATCCAATTGGATCACCATGAACGGTGTGATTGTACCTGCAGCTCCAGACCACCTCGATAAAAGAAT
GTGCATAAACTTATATTGAGCATGAAAGAACCTTTAGTTTAAGAAGGATATGGTAAGGGACCCTTTCCCCACCCCCAGCAACCGAATTTGCTACTAGCCTGAAATACAATGATACGGTCATTGCTGAG
ACGACCTAGCTTTGTTAGTTCTGTGGCAAGTAGAAAGGTGCATCATCAGTTTCTATATCCAAGAATGTAAAACTGCATTTTATAGTAGTATGTGAGGATATATATGTATACACACAAATATATACATA
TGTCCAGGATATGTGTAAATAGATACATGGTTTATTCAGTAGGTACAACCAAGTACACCAGAGTTACATATGGCTGAATGATTTAGACCCTTAATATTTTTCCAAAATAAGGGTAAGGGATATGTCAA
ATATATAACACACATCTGTAGGAAACTCAGAAGATGAACTTTTTATTGTGTTGAATTTTGAATCGCAAACCATTTTGGATCTTGAGCCCTTAAAGAAAGCATCTTGTATATTAAACACATATAGGCTT
TTCTTAGATATCTGCCTTAATTATAAAAAAGGAAAAATATGGTTTGTGGAAAAAAAGACAATTACCTAAGCATTTTTTTCCATGAGATGCACTACACATGCTTGGTAATGTGGACTATAGTTGCCTTT
CTCCAAAATCATGCCATAATAATGTGGGAAATTTAGAAATTAAGTCTCTAAGTTCTCTTTTTATGCATTTTCTGAGACATTCTAATTCATTTAATACCCATCTCAAAAAATATTGCTCAGAGTGTTTA
TCATTATGATCCTTCAAGAGACAAAATTTTAGCAGAATTTTAAATTTTTTTCTCTGCAAAAATTCCTCCAAAATAACAAATCCTTTAATAAATGGCATGGAGATTATGTATGAACCTTTCAAATGGTG
TTCATTGAAAAATTTGGGCAGATGAAAGTCAAAAACCTAAGCATTGAAATATTGACATAACTGGAAATTAGGTGGAATCTTTGATAGGATCCATATTTAATAATGGTTTCAAACTATCCAAACTGTGC
CAATAATTTTATGTATTTTGCTTTTGTGTTCCTGTCTCTTCAATATATACACATGGATTTACAATGGCATTTTATATTTGGAGAGCCATCATGGATTATTTATAACCTAAAAACTTTTGTATATTAAT
AAAGCAAGCAAATTTTATTGATGTAAATCCCTAATTATATCCTCACTTAACATTTCTGAATTTCTATTTCTGATCCAAGTGAAATCAGATCTGGAGTCTTCTGTTCTTTCCAAATCTAGGGAGCCCCC
TGTAAATTATGGGAGTATAAGTTTTGCCCTACTACACCTCTTGAAAACTGTTTTGCATTTGTTAATGATATTTGGAGTAAAATTTTCTCTCTGACTCCTTTGTGTCTATTTTAAAGAGACTGACTTCA
GGAGTAGGAAATGATTCATCATTCTCAAAGCAAGACACTTAAGAAGGAACACTGAGATCAACATAGCTCAAGGGTTGCTCACGGAGGACCACATTTTTCCTCCAGTCTGGAGAGTTAAAGGAGAGCTG
ATTTCTTTCATGAGTCCAGGGTCCTACTGACCACAACCAGTTAGTGTGAGGGAGACGTGCCCCCACTGTCGAGGTCCTGGTGTCAGATGAATGTCCTACATATATTGGGACTTTTATGTACAGTGCTC
TCAGACCCAAGTTGCCAGCTGTCCTCCAGTAGCTTATTTCTTCTTGACTCTTTGAAATAAGACCTACGCTTATTGATGATGGACTTTCTAAAACTCCCCTAAAAGTGTTCAGTGTTTTTACTCAGGGA
ATAAGTGGTGAAATAAAGCACTCTGTTATTCAGTTCTCCTAAAATCCCAGAGCACAGTCAGAAATAGCCCAGGCAGACTAGTCATAATTAGGAGCCACTTCCCTTTCAGGACCACTTGCATAATTTTC
CTGGGAAAACATCAGCTTCCTGTTCCAAAATCAAAATGTGTGTTAACATCACTCACTTTAGCTTGTACAGCTCACATTGTAGCTGTGAATATGAAAAATCCTCCGTGTTCTAACCCAATTTTCAATAA
ACCTCCCAGGCTGCAATAACCAGGATGGTTTTCAGTTAAAGCCCTATCTGTACTTTTTATTTATTAGCTGAGATGTAAGCAGACGTATTCACTCACTTATCCTTTTCTTTCCTGCATGTTTATTAAAA
CTTCTCCCTTGGTTATCTGTTACCTATCGCACTTCCAACGTGTAGCCAATAAATCTGTTCCATTGCCATCAAAGGAATAAAAAGTTCACTGTACAAATTACATTTCAAAACACACCCTAATAAATCCA
CATTGCTGCACAGCTCACTCACCTGGAATAATGCCTTTCATTCAATATGTTCTTATAAAGCAGAACACTTTCGTAAGTAGAATGTTTTATGTTTTTTTGTCATATCGGTAACATGCAGCTTTTTCCTC
TCACAGCATTTTCTATAGCAAATGTAATATGCCTCTTATCTTCATGAAAAATAAATATTGCTTTTGAACAAAA

hide sequence

RefSeq Acc Id:

XM_040285144 ⟹ XP_040141078

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	87,338,657 - 87,562,388 (-)	NCBI


Protein RefSeqs	XP_005329144	(Get FASTA)	NCBI Sequence Viewer
	XP_005329145	(Get FASTA)	NCBI Sequence Viewer
	XP_040141078	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000003794.3
GenBank Protein	KAG3286445	(Get FASTA)	NCBI Sequence Viewer
	KAG3286446	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005329144 ⟸ XM_005329087
- Peptide Label:	isoform X1
- UniProtKB:	I3M3U8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MHRLIFVYTLACANFCSFRDTYATPQSASIKALRNANLRRDESNHLTDLYRKEETIQVTGNGHVQSPRFPNSYPRNLLLTWRLHSQDKTRIQLAFDNQFGLEEAENDICRYDFVEVEDVSETSTVIRG RWCGHKEVPPRITSRTNQIKITFKSDDYFVAKPGFRIYYSFVKDFQPAEASDTNWESVTSSNSGVSYRSSSVTDSALTVEALDKKVAEFDTVEDLLKHFNPESWQDDLENLYLDTPHYRGRSYHERKS KVDLDRLNDDVKRYSCTPRNYSVNLRQELQLTNAVFFPRCLLVQRCGGNCGCGTANSKSCRCNSGKTVKKYHEVLKFEPGNIKRRGLAKNMALVDIQLDHHERCDCTCSSRPPR hide sequence

RefSeq Acc Id:

XP_005329145 ⟸ XM_005329088

- Peptide Label:

isoform X2

- Sequence:

show sequence

MHRLIFVYTLACANFCSFRDTYATPQSASIKALRNANLRRDDLYRKEETIQVTGNGHVQSPRFPNSYPRNLLLTWRLHSQDKTRIQLAFDNQFGLEEAENDICRYDFVEVEDVSETSTVIRGRWCGHK
EVPPRITSRTNQIKITFKSDDYFVAKPGFRIYYSFVKDFQPAEASDTNWESVTSSNSGVSYRSSSVTDSALTVEALDKKVAEFDTVEDLLKHFNPESWQDDLENLYLDTPHYRGRSYHERKSKVDLDR
LNDDVKRYSCTPRNYSVNLRQELQLTNAVFFPRCLLVQRCGGNCGCGTANSKSCRCNSGKTVKKYHEVLKFEPGNIKRRGLAKNMALVDIQLDHHERCDCTCSSRPPR

hide sequence

RefSeq Acc Id:	XP_040141078 ⟸ XM_040285144
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSSTOP00000003794 ⟸ ENSSTOT00000004225

Protein Domains

CUB Platelet-derived growth factor (PDGF) family

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000004230	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000004225.3	UniProtKB/TrEMBL
Gene3D-CATH	2.10.90.10	UniProtKB/TrEMBL
	2.60.120.290	UniProtKB/TrEMBL
InterPro	CUB_dom	UniProtKB/TrEMBL
	Cystine-knot_cytokine	UniProtKB/TrEMBL
	PDGF/VEGF_dom	UniProtKB/TrEMBL
	Sperma_CUB_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Pdgfd	ENTREZGENE
PANTHER	PLATELET-DERIVED GROWTH FACTOR	UniProtKB/TrEMBL
	PTHR11633:SF4	UniProtKB/TrEMBL
Pfam	CUB	UniProtKB/TrEMBL
	PDGF	UniProtKB/TrEMBL
PROSITE	CUB	UniProtKB/TrEMBL
	PDGF_2	UniProtKB/TrEMBL
SMART	CUB	UniProtKB/TrEMBL
	PDGF	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49854	UniProtKB/TrEMBL
	SSF57501	UniProtKB/TrEMBL
UniProt	I3M3U8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)