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Gene: Plpp3 (phospholipid phosphatase 3) Chinchilla lanigera

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Symbol:

Plpp3

Name:

phospholipid phosphatase 3

RGD ID:

8832570

Description:

ENCODES a protein that exhibits ceramide-1-phosphate phosphatase activity (ortholog); delta-catenin binding (ortholog); integrin binding (ortholog); INVOLVED IN Bergmann glial cell differentiation (ortholog); blood vessel development (ortholog); cell adhesion (ortholog); ASSOCIATED WITH Cardiomegaly (ortholog); coronary artery disease (ortholog); Ventricular Dysfunction, Left (ortholog); FOUND IN adherens junction (ortholog); basolateral plasma membrane (ortholog); endoplasmic reticulum exit site (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lipid phosphate phosphohydrolase 3; phosphatidic acid phosphatase type 2B; Ppap2b

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955464	3,081,334 - 3,197,413 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955464	3,122,420 - 3,197,359 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cardiomegaly (ISO)

coronary artery disease (ISO)

Ventricular Dysfunction, Left (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Bergmann glial cell differentiation (ISO)

blood vessel development (ISO)

cell adhesion (ISO)

cell-cell adhesion (ISO)

cell-cell adhesion mediated by integrin (ISO)

ceramide metabolic process (ISO)

gastrulation with mouth forming second (ISO)

integrin-mediated signaling pathway (ISO)

negative regulation of protein phosphorylation (ISO)

phospholipid dephosphorylation (ISO)

phospholipid metabolic process (ISO)

positive regulation of DNA-binding transcription factor activity (ISO)

positive regulation of endothelial cell migration (ISO)

positive regulation of endothelial cell-matrix adhesion via fibronectin (ISO)

positive regulation of homotypic cell-cell adhesion (ISO)

positive regulation of intracellular signal transduction (ISO)

positive regulation of peptidyl-tyrosine phosphorylation (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

protein stabilization (ISO)

regulation of sphingolipid mediated signaling pathway (ISO)

regulation of Wnt signaling pathway (ISO)

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (ISO)

sphingosine metabolic process (ISO)

Cellular Component

adherens junction (ISO)

basolateral plasma membrane (ISO)

endoplasmic reticulum exit site (ISO)

endoplasmic reticulum membrane (ISO)

endoplasmic reticulum-Golgi intermediate compartment membrane (ISO)

Golgi apparatus (ISO)

membrane (ISO)

membrane raft (ISO)

plasma membrane (ISO)

trans-Golgi network (ISO)

Molecular Function

ceramide-1-phosphate phosphatase activity (ISO)

delta-catenin binding (ISO)

integrin binding (ISO)

lipid phosphatase activity (ISO)

phosphatidate phosphatase activity (ISO)

protein binding (ISO)

sphingosine-1-phosphate phosphatase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Plpp3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955464	3,081,334 - 3,197,413 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955464	3,122,420 - 3,197,359 (+)	NCBI	ChiLan1.0	ChiLan1.0

PLPP3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	56,494,761 - 56,579,563 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	56,494,761 - 56,645,301 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	56,960,433 - 57,045,236 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	56,733,021 - 56,817,845 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	55,245,253 - 55,330,133 (-)	NCBI		Celera
Cytogenetic Map	1	p32.2	NCBI
HuRef	1	55,072,892 - 55,157,775 (-)	NCBI		HuRef
CHM1_1	1	57,072,622 - 57,160,617 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	56,373,591 - 56,458,441 (-)	NCBI		T2T-CHM13v2.0

Plpp3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	105,014,544 - 105,089,964 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	105,014,544 - 105,089,961 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	105,157,347 - 105,232,767 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	105,157,347 - 105,232,764 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	104,829,952 - 104,905,372 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	104,655,279 - 104,730,699 (+)	NCBI		MGSCv36	mm8
Celera	4	103,508,199 - 103,583,768 (+)	NCBI		Celera
Cytogenetic Map	4	C6	NCBI
cM Map	4	49.18	NCBI

Plpp3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	125,156,000 - 125,231,119 (+)	NCBI		GRCr8
mRatBN7.2	5	119,927,085 - 120,002,206 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	119,927,085 - 120,002,205 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	122,548,651 - 122,624,021 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	124,271,713 - 124,347,083 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	124,322,955 - 124,398,328 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	124,690,214 - 124,765,499 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	124,690,214 - 124,765,498 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	128,551,196 - 128,626,138 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	126,121,416 - 126,197,099 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	126,126,641 - 126,202,324 (+)	NCBI
Celera	5	118,477,102 - 118,551,973 (+)	NCBI		Celera
Cytogenetic Map	5	q34	NCBI

PLPP3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	170,181,721 - 170,332,442 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	169,400,091 - 169,484,785 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	55,779,343 - 55,862,717 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	57,489,178 - 57,573,307 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	57,489,178 - 57,573,398 (-)	Ensembl	panpan1.1		panPan2

PLPP3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	52,924,443 - 53,006,298 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	52,923,833 - 53,005,493 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	52,992,430 - 53,074,349 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	53,112,365 - 53,194,538 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	53,112,379 - 53,194,536 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	53,055,985 - 53,137,860 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	53,001,878 - 53,083,760 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	53,386,869 - 53,468,888 (+)	NCBI		UU_Cfam_GSD_1.0

Plpp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	70,341,999 - 70,423,866 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936522	4,992,322 - 5,074,313 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936522	4,992,333 - 5,074,295 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLPP3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	155,800,678 - 155,894,912 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	155,800,838 - 155,894,919 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	143,642,088 - 143,734,081 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLPP3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	76,382,041 - 76,466,497 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	76,382,079 - 76,477,847 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	40,825,335 - 40,909,946 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Plpp3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624862	3,550,968 - 3,627,058 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624862	3,550,498 - 3,627,061 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013521597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013521598	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01049971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01049972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01134336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000008022 ⟹ ENSCLAP00000007902

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955464	3,081,334 - 3,197,413 (+)	Ensembl

Ensembl Acc Id:

ENSCLAT00000008023 ⟹ ENSCLAP00000007903

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955464	3,122,701 - 3,195,587 (+)	Ensembl

Ensembl Acc Id:

ENSCLAT00000008024 ⟹ ENSCLAP00000007904

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955464	3,135,263 - 3,197,413 (+)	Ensembl

RefSeq Acc Id:

XM_013521597 ⟹ XP_013377051

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955464	3,122,420 - 3,197,359 (+)	NCBI

Sequence:

show sequence

AAAACAAACCGAGCGGCCGCAGCTGCAGCAGCAGAAGGAGGCGGAGGCGGAGGCGTAGCCGGAG
TCGGTGGCGCTGCGGGCCGCGGAGCTCGGCGCTGCCCATTCATTGCGCGGCCGCGGAGGAGGCG
GCCGGAGCCCCGGTGCCCCTCGCCCGCGCGCACACAGCCCCGGCCCCGCCGTCCTGCCCGGCGC
TGCAGCCTCCGCTCGGGACCCGCGCTCTCCCGGGACGTTCGCGCGAGCGGGGCGGAGCGGAGCG
GAGACAGCGCGGCCGAGCCAGCGCCATGCAGAGCTACAAGTACGACAAGGCGATCGCGCCCGAG
AGCAAGAACGGCGGCGGCCCCGCGCTCGGCCCCGGCCCGCGCAGAAGCGGCGGCAAGCGCGCGC
TGCTCATCTGCCTCGACCTCCTGTGCCTGTTCCTGGCCAGCCTGCCCTTCCTCATCATTGAGAC
GAGCACCATCAAGCCTTATCGCCGAGGATTTTACTGCAACGACGAGAGCATCAAGTACCCGCTG
AAAGTCGGGGAGACCATCAATGATGCTGTGCTCTGTGCGGTGGGGATCGTGATTGCCATCCTCG
CAATCATCACGGGAGAATTCTACCGCATCTACTACCTGAAGGAGAAGTCCCGCTCCACGATTCA
GAACCCCTACGTGGCGGCCCTCTATAAGCAAGTGGGTTGCTTCCTCTTTGGCTGCGCCATCAGC
CAGTCTTTTACTGACATTGCAAAAGTGTCCATAGGGCGCCTGCGCCCCCACTTCTTGAGTGTCT
GCGACCCGGATTTCAGCCAGATCAACTGCTCCGAGGGCTACATTCAGACCTACCAATGCAGAGG
CCCCGAGAGCAAAGTTCAGGAAGCCAGGAAGTCCTTCTTCTCGGGCCATGCGTCCTTCTCCATG
TACACGATGCTGTATTTGGTGCTGTACCTGCAGGCCCGCTTCACCTGGAGAGGTGCCCGCCTGC
TCCGGCCCCTCCTGCAGTTCACCTTGATCATGATGGCCTTCTACACAGGACTGTCCCGCATATC
TGACCACAAGCACCACCCCAGTGATGTCCTGGCAGGGTTTGCCCAAGGAGCCCTGGTGTCCTGC
TGCATAGTATTCTTCGTGTCGGACCTCTTCAAGACCAAGACAACACTCTCCCTGCCTCCCACTG
CGATCAGGAAGGAGGTCCTCTCCCCTGTGGATGTCATTGACAGGAACAATCGCCACAACATGGT
GTAGGTGCTGCCCGCCTCCTGCGTGGGTCCTGTAAAGTGACTGCTGACAGCAAGTTCTTGCTGC
TCTCTCCAATCTCATCAGACAGTAGAATGTAGGGAAAAACTTTTCGCCCAACTGATTTTAAAAA
AAGAAAAAAAAAAGTCTTACTTTGTGGCCTTCCAGAATAGGTAGTGCTCACCTATGTGGAAACG
ACAGCAGAATGACACCGAGTGTGGAGGCGCAGATGTGCAATGGGTTCCGTGTTCAGTTCTAGTG
AGCATGGCCCGTTCAGGAGCGAGCAGTAGCATGATGTGAGCAGAGGCTGCTGGGCTCCTTGCGA
GCTGAGAACCCCCAGGCCTGTGAGAAAAGCGCAAATTCGCACGGTAGCATGCGGAGCCAGATCA
CACTGAGTGCAGAACTTGGCCGTGGGGCTCGCCTCTCCCAGCCCTCTGCCCATCCCACTCAACT
CTCCACTGTGACTTTAGTGCAGGAAGTTTTGTTTCGGTTTTTAAACATAAGGAACGAGCAGGTT
TGCTTGGTCCGGGGATCAGACCCTGAATCCAAATCCCCAGTCCTAAGGCCTTCGTCACCTTTCC
AGTCCACAGCCGCGGCCCCTCACAATAGAGATTAGGAGACTCTTTGTGGAAGAGTGAACTTCAC
AAATAGCACAATTTCAGAAGAGATGGAGGGCACAAGCCCTCCTGTGTCTTCTTTGACTCGTCAC
CCTGTGGTGTGGAAATGTCGCACACAGGATGCCGATGTGTACACGAATCACCGGGCACTTCACA
CTTAGAAATGGCTAGACTTTGGTTCTTGTGGTCTCCCTTGAAATCATTGTGTGTGCCTACGGGG
ATTTCTGGTGAGGGTCCAGAGATGAGCAGAGGCATAGTCTGGCTTCTGTGCAAGACACAAGGGA
GCAGAGGGGCAGAGGGAAAGGTGACCACCCTTTTGGCTACTGGAAGCCAGAAGGAGCCAGAATG
GCAGATGGTTTCAGGCCTGACAGGCTGCCCTTCAAAGTAACGGAGTGGAGAGGGTCTTGGTGGG
AGTTGCTCTTGCTGAGCTGTGTAAAGCACTATTGTCTTGGGGTTGACCCCTAGGGCAGTTCTTG
GTAGGTTCTGCTGGGCAGAACACATGGGTTAAATCTCCGCAGAGAGCTTTCCTCGTCCTCCATC
CACAAGTGTCCTTCCAAGAGAGGTCCCACTGTAGGCGGTAAGCAGGGACCCCTTCTCTTGAACC
TCTGAGGAAAGGAGGAAGAAATGCTTCTCAACCTTGGATGCGAACCTTTCAAAGGGCTACATGT
AACCAATGGGTCAACCACATGCACATCATTACCACAGAATCCGTCCTTTCATTTCAACGTATAG
CAAGCTATGATTTTTATATATAAATATTATATAAATAATGTATAAAACATTAAAAGTTAACTAT
GTAAAATATTATTTCTGAAACAATTTTAGCTATATCCACTACGATTATAAACGGTGTCTTGACC
TGTGTTATTTACTTTAGCTGCTTAAAAAAGCATTGAGTTAATTTTTTAAAATCTCGACTAAAAA
TATCGTAGCTCTGTGGTAGCCATTGTTTTACAATGAGAGAAATAACTGCAACTAGAGAAAACTG
TATAAAAACATTAAATTGTCAGTATTTTTGTAAGATTCCATTTTGTAAAGAGAATAATATTCAA
AGACTTTTGTAGCATACAAAGTGAAAACTTGTATCTGCGAAACTATACTTGTATTAAATGTGCT
TTTTAAATAAAAGCTCATAACACAACTAAGTAAAGCATTGGAAGCCTG

hide sequence

RefSeq Acc Id:

XM_013521598 ⟹ XP_013377052

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955464	3,159,088 - 3,197,359 (+)	NCBI

Sequence:

show sequence

CTGAGGCTCACAGAAATGGCCAGCCTGCCCTTCCTCATCATTGAGACGAGCACCATCAAGCCTT
ATCGCCGAGGATTTTACTGCAACGACGAGAGCATCAAGTACCCGCTGAAAGTCGGGGAGACCAT
CAATGATGCTGTGCTCTGTGCGGTGGGGATCGTGATTGCCATCCTCGCAATCATCACGGGAGAA
TTCTACCGCATCTACTACCTGAAGGAGAAGTCCCGCTCCACGATTCAGAACCCCTACGTGGCGG
CCCTCTATAAGCAAGTGGGTTGCTTCCTCTTTGGCTGCGCCATCAGCCAGTCTTTTACTGACAT
TGCAAAAGTGTCCATAGGGCGCCTGCGCCCCCACTTCTTGAGTGTCTGCGACCCGGATTTCAGC
CAGATCAACTGCTCCGAGGGCTACATTCAGACCTACCAATGCAGAGGCCCCGAGAGCAAAGTTC
AGGAAGCCAGGAAGTCCTTCTTCTCGGGCCATGCGTCCTTCTCCATGTACACGATGCTGTATTT
GGTGCTGTACCTGCAGGCCCGCTTCACCTGGAGAGGTGCCCGCCTGCTCCGGCCCCTCCTGCAG
TTCACCTTGATCATGATGGCCTTCTACACAGGACTGTCCCGCATATCTGACCACAAGCACCACC
CCAGTGATGTCCTGGCAGGGTTTGCCCAAGGAGCCCTGGTGTCCTGCTGCATAGTATTCTTCGT
GTCGGACCTCTTCAAGACCAAGACAACACTCTCCCTGCCTCCCACTGCGATCAGGAAGGAGGTC
CTCTCCCCTGTGGATGTCATTGACAGGAACAATCGCCACAACATGGTGTAGGTGCTGCCCGCCT
CCTGCGTGGGTCCTGTAAAGTGACTGCTGACAGCAAGTTCTTGCTGCTCTCTCCAATCTCATCA
GACAGTAGAATGTAGGGAAAAACTTTTCGCCCAACTGATTTTAAAAAAAGAAAAAAAAAAGTCT
TACTTTGTGGCCTTCCAGAATAGGTAGTGCTCACCTATGTGGAAACGACAGCAGAATGACACCG
AGTGTGGAGGCGCAGATGTGCAATGGGTTCCGTGTTCAGTTCTAGTGAGCATGGCCCGTTCAGG
AGCGAGCAGTAGCATGATGTGAGCAGAGGCTGCTGGGCTCCTTGCGAGCTGAGAACCCCCAGGC
CTGTGAGAAAAGCGCAAATTCGCACGGTAGCATGCGGAGCCAGATCACACTGAGTGCAGAACTT
GGCCGTGGGGCTCGCCTCTCCCAGCCCTCTGCCCATCCCACTCAACTCTCCACTGTGACTTTAG
TGCAGGAAGTTTTGTTTCGGTTTTTAAACATAAGGAACGAGCAGGTTTGCTTGGTCCGGGGATC
AGACCCTGAATCCAAATCCCCAGTCCTAAGGCCTTCGTCACCTTTCCAGTCCACAGCCGCGGCC
CCTCACAATAGAGATTAGGAGACTCTTTGTGGAAGAGTGAACTTCACAAATAGCACAATTTCAG
AAGAGATGGAGGGCACAAGCCCTCCTGTGTCTTCTTTGACTCGTCACCCTGTGGTGTGGAAATG
TCGCACACAGGATGCCGATGTGTACACGAATCACCGGGCACTTCACACTTAGAAATGGCTAGAC
TTTGGTTCTTGTGGTCTCCCTTGAAATCATTGTGTGTGCCTACGGGGATTTCTGGTGAGGGTCC
AGAGATGAGCAGAGGCATAGTCTGGCTTCTGTGCAAGACACAAGGGAGCAGAGGGGCAGAGGGA
AAGGTGACCACCCTTTTGGCTACTGGAAGCCAGAAGGAGCCAGAATGGCAGATGGTTTCAGGCC
TGACAGGCTGCCCTTCAAAGTAACGGAGTGGAGAGGGTCTTGGTGGGAGTTGCTCTTGCTGAGC
TGTGTAAAGCACTATTGTCTTGGGGTTGACCCCTAGGGCAGTTCTTGGTAGGTTCTGCTGGGCA
GAACACATGGGTTAAATCTCCGCAGAGAGCTTTCCTCGTCCTCCATCCACAAGTGTCCTTCCAA
GAGAGGTCCCACTGTAGGCGGTAAGCAGGGACCCCTTCTCTTGAACCTCTGAGGAAAGGAGGAA
GAAATGCTTCTCAACCTTGGATGCGAACCTTTCAAAGGGCTACATGTAACCAATGGGTCAACCA
CATGCACATCATTACCACAGAATCCGTCCTTTCATTTCAACGTATAGCAAGCTATGATTTTTAT
ATATAAATATTATATAAATAATGTATAAAACATTAAAAGTTAACTATGTAAAATATTATTTCTG
AAACAATTTTAGCTATATCCACTACGATTATAAACGGTGTCTTGACCTGTGTTATTTACTTTAG
CTGCTTAAAAAAGCATTGAGTTAATTTTTTAAAATCTCGACTAAAAATATCGTAGCTCTGTGGT
AGCCATTGTTTTACAATGAGAGAAATAACTGCAACTAGAGAAAACTGTATAAAAACATTAAATT
GTCAGTATTTTTGTAAGATTCCATTTTGTAAAGAGAATAATATTCAAAGACTTTTGTAGCATAC
AAAGTGAAAACTTGTATCTGCGAAACTATACTTGTATTAAATGTGCTTTTTAAATAAAAGCTCA
TAACACAACTAAGTAAAGCATTGGAAGCCTG

hide sequence

Protein Sequences


Protein RefSeqs	XP_013377051	(Get FASTA)	NCBI Sequence Viewer
	XP_013377052	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000007902.1
	ENSCLAP00000007903
	ENSCLAP00000007903.1
	ENSCLAP00000007904
	ENSCLAP00000007904.1

RefSeq Acc Id:	XP_013377051 ⟸ XM_013521597
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2V460 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQSYKYDKAIAPESKNGGGPALGPGPRRSGGKRALLICLDLLCLFLASLPFLIIETSTIKPYRR GFYCNDESIKYPLKVGETINDAVLCAVGIVIAILAIITGEFYRIYYLKEKSRSTIQNPYVAALY KQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCDPDFSQINCSEGYIQTYQCRGPESKVQEA RKSFFSGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFTLIMMAFYTGLSRISDHKHHPSD VLAGFAQGALVSCCIVFFVSDLFKTKTTLSLPPTAIRKEVLSPVDVIDRNNRHNMV hide sequence

RefSeq Acc Id:	XP_013377052 ⟸ XM_013521598
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2UZ51 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASLPFLIIETSTIKPYRRGFYCNDESIKYPLKVGETINDAVLCAVGIVIAILAIITGEFYRIY YLKEKSRSTIQNPYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCDPDFSQINCS EGYIQTYQCRGPESKVQEARKSFFSGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFTLIM MAFYTGLSRISDHKHHPSDVLAGFAQGALVSCCIVFFVSDLFKTKTTLSLPPTAIRKEVLSPVD VIDRNNRHNMV hide sequence

Ensembl Acc Id:

ENSCLAP00000007902 ⟸ ENSCLAT00000008022

Ensembl Acc Id:

ENSCLAP00000007903 ⟸ ENSCLAT00000008023

Ensembl Acc Id:

ENSCLAP00000007904 ⟸ ENSCLAT00000008024

Protein Domains

Phosphatidic acid phosphatase type 2/haloperoxidase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000005538	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000008022.1	UniProtKB/TrEMBL
	ENSCLAT00000008023	ENTREZGENE
	ENSCLAT00000008023.1	UniProtKB/TrEMBL
	ENSCLAT00000008024	ENTREZGENE
	ENSCLAT00000008024.1	UniProtKB/TrEMBL
Gene3D-CATH	Phosphatidic acid phosphatase type 2/haloperoxidase	UniProtKB/TrEMBL
InterPro	P_Acid_Pase_2/haloperoxi_sf	UniProtKB/TrEMBL
	P_Acid_Pase_2/haloperoxidase	UniProtKB/TrEMBL
	PA_PP_rel	UniProtKB/TrEMBL
NCBI Gene	Ppap2b	ENTREZGENE
PANTHER	PTHR10165	UniProtKB/TrEMBL
	PTHR10165:SF79	UniProtKB/TrEMBL
Pfam	PAP2	UniProtKB/TrEMBL
SMART	acidPPc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48317	UniProtKB/TrEMBL
UniProt	A0A8C2UZ51	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2V1C3_CHILA	UniProtKB/TrEMBL
	A0A8C2V460	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Plpp3	phospholipid phosphatase 3	Ppap2b	phosphatidic acid phosphatase type 2B	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD