Abca7 (ATP binding cassette subfamily A member 7) - Rat Genome Database

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Gene: Abca7 (ATP binding cassette subfamily A member 7) Chinchilla lanigera
Analyze
Symbol: Abca7
Name: ATP binding cassette subfamily A member 7
RGD ID: 8824148
Description: ENCODES a protein that exhibits apolipoprotein A-I receptor activity (ortholog); floppase activity (ortholog); phosphatidylcholine floppase activity (ortholog); INVOLVED IN amyloid-beta clearance by cellular catabolic process (ortholog); amyloid-beta formation (ortholog); apolipoprotein A-I-mediated signaling pathway (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 9 (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN apical plasma membrane (ortholog); cell junction (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-binding cassette sub-family A member 7; ATP-binding cassette, sub-family A (ABC1), member 7
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,815,562 - 6,836,772 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,818,002 - 6,838,177 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Abca7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,815,562 - 6,836,772 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,818,002 - 6,838,177 (-)NCBIChiLan1.0ChiLan1.0
ABCA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,040,107 - 1,065,572 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,039,997 - 1,065,572 (+)EnsemblGRCh38hg38GRCh38
GRCh37191,040,106 - 1,065,571 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619991,102 - 1,016,571 (+)NCBINCBI36Build 36hg18NCBI36
Celera19970,935 - 998,554 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef19812,691 - 838,952 (+)NCBIHuRef
CHM1_1191,038,376 - 1,065,164 (+)NCBICHM1_1
T2T-CHM13v2.0191,002,776 - 1,030,237 (+)NCBIT2T-CHM13v2.0
Abca7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,832,328 - 79,851,406 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,832,328 - 79,851,406 (+)EnsemblGRCm39 Ensembl
GRCm381079,996,453 - 80,015,572 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,996,494 - 80,015,572 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,460,360 - 79,478,317 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,400,744 - 79,418,701 (+)NCBIMGSCv36mm8
Celera1081,012,422 - 81,030,379 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Abca7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,342,092 - 10,362,094 (-)NCBIGRCr8
mRatBN7.279,691,452 - 9,711,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,691,449 - 9,711,425 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,573,976 - 12,592,469 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,449,312 - 14,467,805 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,310,438 - 12,328,932 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,742,433 - 12,762,423 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,742,433 - 12,762,341 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,912,155 - 12,932,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,203,983 - 11,222,960 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1711,203,982 - 11,222,960 (-)NCBI
Celera77,867,206 - 7,885,960 (-)NCBICelera
Cytogenetic Map7q11NCBI
ABCA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,374,938 - 5,401,483 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,611,225 - 4,637,922 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01962,811 - 77,897 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1191,016,829 - 1,042,251 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl191,018,095 - 1,042,104 (+)Ensemblpanpan1.1panPan2
ABCA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,668,371 - 57,684,111 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,667,706 - 57,677,342 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,470,691 - 57,486,228 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,410,598 - 58,426,136 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,410,507 - 58,425,315 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,465,893 - 57,481,504 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,945,423 - 57,961,034 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,148,479 - 58,164,018 (-)NCBIUU_Cfam_GSD_1.0
Abca7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,357,348 - 217,374,569 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588461,389 - 477,229 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588460,308 - 477,382 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCA7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,357,218 - 77,375,180 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,357,161 - 77,375,349 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,621,720 - 77,640,442 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103233590
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16792,684 - 821,522 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl6792,783 - 821,375 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660818,035,915 - 8,121,412 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abca7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,573,130 - 7,591,038 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,572,821 - 7,592,428 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000017463   ⟹   ENSCLAP00000017294
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554956,815,562 - 6,836,772 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000017464   ⟹   ENSCLAP00000017295
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554956,818,130 - 6,836,772 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000017465   ⟹   ENSCLAP00000017296
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554956,818,130 - 6,836,772 (-)Ensembl
RefSeq Acc Id: XM_013505096   ⟹   XP_013360550
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,818,002 - 6,838,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505097   ⟹   XP_013360551
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,818,002 - 6,838,022 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505098   ⟹   XP_013360552
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,818,002 - 6,837,457 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505099   ⟹   XP_013360553
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,818,002 - 6,837,457 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505100   ⟹   XP_013360554
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,818,002 - 6,837,457 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505101   ⟹   XP_013360555
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,818,534 - 6,837,457 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013505102   ⟹   XP_013360556
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,820,727 - 6,837,457 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013360550   ⟸   XM_013505096
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VL58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360551   ⟸   XM_013505097
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VL58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360553   ⟸   XM_013505099
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VL58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360552   ⟸   XM_013505098
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VL78 (UniProtKB/TrEMBL),   A0A8C2VL58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360554   ⟸   XM_013505100
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VL58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360555   ⟸   XM_013505101
- Peptide Label: isoform X5
- UniProtKB: A0A8C2VL58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360556   ⟸   XM_013505102
- Peptide Label: isoform X6
- UniProtKB: A0A8C2VL58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000017295   ⟸   ENSCLAT00000017464
RefSeq Acc Id: ENSCLAP00000017296   ⟸   ENSCLAT00000017465
RefSeq Acc Id: ENSCLAP00000017294   ⟸   ENSCLAT00000017463
Protein Domains
ABC transporter   Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011872 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000017463 ENTREZGENE
  ENSCLAT00000017463.1 UniProtKB/TrEMBL
  ENSCLAT00000017464 ENTREZGENE
  ENSCLAT00000017464.1 UniProtKB/TrEMBL
  ENSCLAT00000017465.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC2_TM UniProtKB/TrEMBL
  ABC_transporter-like_ATP-bd UniProtKB/TrEMBL
  ABC_transporter-like_CS UniProtKB/TrEMBL
  ABCA UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Abca7 ENTREZGENE
PANTHER PHOSPHOLIPID-TRANSPORTING ATPASE ABCA7 UniProtKB/TrEMBL
  PTHR19229 UniProtKB/TrEMBL
Pfam AAA_21 UniProtKB/TrEMBL
  ABC2_membrane_3 UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PROSITE ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C2VL58 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VL78 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YR71_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Abca7  ATP binding cassette subfamily A member 7    ATP-binding cassette, sub-family A (ABC1), member 7  Symbol and/or name change 5135510 APPROVED