Homer3 (homer scaffold protein 3) - Rat Genome Database

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Gene: Homer3 (homer scaffold protein 3) Chinchilla lanigera
Analyze
Symbol: Homer3
Name: homer scaffold protein 3
RGD ID: 8820867
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of calcineurin-NFAT signaling cascade (ortholog); negative regulation of interleukin-2 production (ortholog); regulation of postsynaptic neurotransmitter receptor activity (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Keratoconus 5 (ortholog); Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1 (ortholog); FOUND IN basal part of cell (ortholog); cytosol (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homer homolog 3; homer protein homolog 3; homer scaffolding protein 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,755,367 - 2,760,198 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,754,970 - 2,760,198 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Homer3ChinchillaKeratoconus 5  ISOHOMER3 (Homo sapiens)8554872ClinVar Annotator: match by term: Keratoconus 5ClinVar 
Homer3ChinchillaMegalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1  ISOHOMER3 (Homo sapiens)8554872ClinVar Annotator: match by term: Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1ClinVarPMID:28492532
Homer3Chinchillaprogressive myoclonus epilepsy 8  ISOHOMER3 (Homo sapiens)8554872ClinVar Annotator: match by term: Progressive myoclonic epilepsy type 8ClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Homer3Chinchillaadenoid cystic carcinoma  ISOHOMER3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16762588
Homer3ChinchillaSalivary Gland Neoplasms  ISOHOMER3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16762588


Biological Process

  

Cellular Component

  

Molecular Function
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Homer3Chinchillaidentical protein binding enablesISOUniProtKB:Q9NSC59068941 PMID:25416956 more ...IntActPMID:25416956 more ...
Homer3Chinchillaprotein binding enablesISOUniProtKB:A1L1C6 more ...9068941 PMID:32296183IntActPMID:32296183
Homer3Chinchillaprotein binding enablesISOPR:P630159068941 PMID:16098226MGIPMID:16098226
Homer3Chinchillaprotein binding enablesISOUniProtKB:Q605919068941 PMID:18218901UniProtPMID:18218901
Homer3Chinchillaprotein binding enablesISOPR:P977729068941 PMID:18480293MGIPMID:18480293
Homer3Chinchillaprotein binding enablesISOUniProtKB:Q9WV489068941 PMID:19345194UniProtPMID:19345194
Homer3Chinchillaprotein binding enablesISOUniProtKB:O95644 more ...9068941 PMID:18218901UniProtPMID:18218901
Homer3Chinchillaprotein binding enablesISOUniProtKB:Q5JVL49068941 PMID:25910212IntActPMID:25910212
Homer3Chinchillaprotein binding enablesISOUniProtKB:O94915 and UniProtKB:Q96FJ29068941 PMID:16189514IntActPMID:16189514
Homer3Chinchillaprotein binding enablesISOUniProtKB:O94915 more ...9068941 PMID:33961781IntActPMID:33961781
Homer3Chinchillaprotein binding enablesISOUniProtKB:Q86YM79068941 PMID:35271311IntActPMID:35271311
Homer3Chinchillaprotein binding enablesISOUniProtKB:Q145179068941 PMID:16979624IntActPMID:16979624
Homer3Chinchillaprotein binding enablesISOUniProtKB:P05067-89068941 PMID:18387811IntActPMID:18387811
Homer3Chinchillaprotein binding enablesISOUniProtKB:A0A3N4B5W9 and UniProtKB:Q569739068941 PMID:21911467IntActPMID:21911467
Homer3Chinchillaprotein binding enablesISOUniProtKB:Q9P2A49068941 PMID:19060904IntActPMID:19060904
Homer3Chinchillaprotein binding enablesISOUniProtKB:P263679068941 PMID:16098226IntActPMID:16098226
Homer3Chinchillaprotein binding enablesISOUniProtKB:Q9NYB99068941 PMID:29892012IntActPMID:29892012
Homer3Chinchillaprotein binding enablesISOUniProtKB:A0A0S2Z470 and UniProtKB:Q927339068941 PMID:26871637IntActPMID:26871637
Homer3Chinchillaprotein binding enablesISOUniProtKB:P00540 more ...9068941 PMID:21516116IntActPMID:21516116
Homer3Chinchillaprotein binding enablesISOUniProtKB:O15371 more ...9068941 PMID:25416956IntActPMID:25416956
1 to 20 of 21 rows


#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:22301074   PMID:30032202  



Homer3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,755,367 - 2,760,198 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,754,970 - 2,760,198 (+)NCBIChiLan1.0ChiLan1.0
HOMER3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,929,201 - 18,941,217 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,929,201 - 18,941,261 (-)EnsemblGRCh38hg38GRCh38
GRCh371919,040,010 - 19,052,026 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,901,012 - 18,912,983 (-)NCBINCBI36Build 36hg18NCBI36
Build 341918,901,011 - 18,912,983NCBI
Celera1918,944,833 - 18,956,865 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,604,424 - 18,624,135 (-)NCBIHuRef
CHM1_11919,039,677 - 19,051,708 (-)NCBICHM1_1
T2T-CHM13v2.01919,064,989 - 19,077,095 (-)NCBIT2T-CHM13v2.0
Homer3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,735,529 - 70,747,011 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,735,477 - 70,747,011 (+)EnsemblGRCm39 Ensembl
GRCm38870,282,880 - 70,294,361 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,282,827 - 70,294,361 (+)EnsemblGRCm38mm10GRCm38
MGSCv37872,806,898 - 72,818,260 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,212,039 - 73,223,342 (+)NCBIMGSCv36mm8
Celera872,839,497 - 72,850,859 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Homer3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,166,141 - 19,176,701 (-)NCBIGRCr8
mRatBN7.21619,132,177 - 19,142,739 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,132,162 - 19,142,680 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1619,173,049 - 19,180,462 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,305,565 - 20,312,954 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,226,010 - 19,233,424 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,880,447 - 20,890,968 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,881,518 - 20,890,949 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,732,220 - 20,742,730 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,617,526 - 19,624,915 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,617,523 - 19,624,913 (-)NCBI
Celera1619,323,520 - 19,330,908 (-)NCBICelera
Cytogenetic Map16p14NCBI
HOMER3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,790,511 - 23,802,790 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,796,727 - 22,808,991 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,367,191 - 18,379,454 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,374,442 - 19,386,161 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,374,442 - 19,385,392 (-)Ensemblpanpan1.1panPan2
HOMER3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,179,145 - 44,186,814 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,179,153 - 44,186,814 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,094,561 - 44,102,222 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,666,088 - 44,673,749 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,666,149 - 44,675,444 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12043,903,365 - 43,911,026 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,313,573 - 44,321,234 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,589,003 - 44,596,702 (+)NCBIUU_Cfam_GSD_1.0
Homer3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118202,856,647 - 202,864,512 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,406,326 - 2,413,604 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,406,427 - 2,413,651 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOMER3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,913,992 - 58,922,474 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1258,913,949 - 58,922,474 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2258,714,495 - 58,721,277 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOMER3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,385,176 - 17,396,506 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,385,175 - 17,394,319 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660741,926,336 - 1,937,877 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Homer3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,971,064 - 1,976,152 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,970,739 - 1,977,750 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSCLAT00000017067   ⟹   ENSCLAP00000016901
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555242,755,367 - 2,760,198 (+)Ensembl
RefSeq Acc Id: XM_005409602   ⟹   XP_005409659
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555242,755,367 - 2,760,198 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005409603   ⟹   XP_005409660
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555242,754,970 - 2,760,198 (+)NCBI
Sequence:
Protein RefSeqs XP_005409659 (Get FASTA)   NCBI Sequence Viewer  
  XP_005409660 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000016901
  ENSCLAP00000016901.1
RefSeq Acc Id: XP_005409659   ⟸   XM_005409602
- UniProtKB: A0A8C2YR01 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005409660   ⟸   XM_005409603
- UniProtKB: A0A8C2YR01 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000016901   ⟸   ENSCLAT00000017067
WH1



1 to 16 of 16 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000011599 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000017067 ENTREZGENE
  ENSCLAT00000017067.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1700 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Homer UniProtKB/TrEMBL
  Homer_EVH1 UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  WH1/EVH1_dom UniProtKB/TrEMBL
NCBI Gene Homer3 ENTREZGENE
PANTHER PTHR10918 UniProtKB/TrEMBL
Pfam WH1 UniProtKB/TrEMBL
PROSITE WH1 UniProtKB/TrEMBL
SMART WH1 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A8C2YR01 ENTREZGENE, UniProtKB/TrEMBL
1 to 16 of 16 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-06 Homer3  homer scaffold protein 3    homer scaffolding protein 3  Symbol and/or name change 5135510 APPROVED
2015-08-25 Homer3  homer scaffolding protein 3    homer homolog 3 (Drosophila)  Symbol and/or name change 5135510 APPROVED