Tspan12 (tetraspanin 12) - Rat Genome Database

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Gene: Tspan12 (tetraspanin 12) Chinchilla lanigera
Analyze
Symbol: Tspan12
Name: tetraspanin 12
RGD ID: 8809700
Description: ENCODES a protein that exhibits Wnt receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); maintenance of blood-brain barrier (ortholog); Norrin signaling pathway (ortholog); ASSOCIATED WITH Disease Susceptibility (ortholog); early myoclonic encephalopathy (ortholog); exudative vitreoretinopathy (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tetraspanin-12
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554792,570,937 - 2,635,857 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554792,570,937 - 2,636,884 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tspan12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554792,570,937 - 2,635,857 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554792,570,937 - 2,636,884 (-)NCBIChiLan1.0ChiLan1.0
TSPAN12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387120,787,320 - 120,858,335 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7120,787,320 - 120,858,402 (-)EnsemblGRCh38hg38GRCh38
GRCh377120,427,374 - 120,498,198 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367120,214,610 - 120,285,413 (-)NCBINCBI36Build 36hg18NCBI36
Build 347120,021,325 - 120,092,128NCBI
Celera7115,236,877 - 115,307,696 (-)NCBICelera
Cytogenetic Map7q31.31NCBI
HuRef7114,790,536 - 114,861,356 (-)NCBIHuRef
CHM1_17120,360,669 - 120,431,498 (-)NCBICHM1_1
T2T-CHM13v2.07122,102,649 - 122,173,766 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27119,822,450 - 119,893,269 (-)NCBI
Tspan12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39621,771,390 - 21,879,557 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl621,771,394 - 21,852,514 (-)EnsemblGRCm39 Ensembl
GRCm38621,771,391 - 21,879,596 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl621,771,395 - 21,852,515 (-)EnsemblGRCm38mm10GRCm38
MGSCv37621,721,395 - 21,802,515 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36621,721,396 - 21,802,516 (-)NCBIMGSCv36mm8
Celera621,825,255 - 21,906,372 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map68.73NCBI
Tspan12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8451,279,562 - 51,355,030 (-)NCBIGRCr8
mRatBN7.2450,313,768 - 50,389,246 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl450,313,772 - 50,389,246 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx455,292,888 - 55,371,672 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0451,213,970 - 51,292,754 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0449,642,270 - 49,717,776 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0448,852,823 - 48,953,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl448,852,827 - 48,928,372 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0448,641,401 - 48,715,044 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4448,084,836 - 48,164,956 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1448,315,410 - 48,395,530 (-)NCBI
Celera445,518,037 - 45,592,649 (-)NCBICelera
Cytogenetic Map4q22NCBI
TSPAN12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26157,651,672 - 157,722,565 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan179,661,929 - 9,732,821 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07112,790,606 - 112,861,730 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17125,478,472 - 125,549,091 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7125,478,472 - 125,549,091 (-)Ensemblpanpan1.1panPan2
TSPAN12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11458,941,658 - 59,005,507 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1458,941,551 - 59,005,463 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1458,358,992 - 58,423,887 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01458,977,034 - 59,042,565 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1458,976,838 - 59,041,886 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11459,071,214 - 59,136,845 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01458,694,898 - 58,759,920 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01459,073,370 - 59,138,262 (-)NCBIUU_Cfam_GSD_1.0
Tspan12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511847,865,412 - 47,938,462 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366054,265,316 - 4,338,526 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366054,265,475 - 4,338,518 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPAN12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1826,046,703 - 26,112,918 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11826,046,645 - 26,112,924 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21827,651,287 - 27,717,509 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TSPAN12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12189,609,229 - 89,680,446 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2189,609,124 - 89,680,297 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604213,900,003 - 13,970,881 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tspan12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478315,226,852 - 15,285,931 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478315,226,927 - 15,285,931 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000006797   ⟹   ENSCLAP00000006687
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554792,570,937 - 2,635,857 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000006798   ⟹   ENSCLAP00000006688
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554792,572,195 - 2,635,779 (-)Ensembl
RefSeq Acc Id: XM_013503288   ⟹   XP_013358742
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554792,570,937 - 2,636,884 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013358742 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000006687.1
  ENSCLAP00000006688.1
RefSeq Acc Id: XP_013358742   ⟸   XM_013503288
- Sequence:
Ensembl Acc Id: ENSCLAP00000006688   ⟸   ENSCLAT00000006798
Ensembl Acc Id: ENSCLAP00000006687   ⟸   ENSCLAT00000006797


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004712 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006797.1 UniProtKB/TrEMBL
  ENSCLAT00000006798.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1450.10 UniProtKB/TrEMBL
InterPro Tetraspanin/Peripherin UniProtKB/TrEMBL
  Tetraspanin_animals UniProtKB/TrEMBL
  Tetraspanin_CS UniProtKB/TrEMBL
  Tetraspanin_EC2_sf UniProtKB/TrEMBL
NCBI Gene Tspan12 ENTREZGENE
PANTHER PTHR19282 UniProtKB/TrEMBL
  TETRASPANIN-12 UniProtKB/TrEMBL
Pfam Tetraspanin UniProtKB/TrEMBL
PIRSF Tetraspanin UniProtKB/TrEMBL
PRINTS TMFOUR UniProtKB/TrEMBL
PROSITE TM4_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48652 UniProtKB/TrEMBL
UniProt A0A8C2UZT9_CHILA UniProtKB/TrEMBL
  A0A8C2V292_CHILA UniProtKB/TrEMBL