TSPAN12 (tetraspanin 12) - Rat Genome Database

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Gene: TSPAN12 (tetraspanin 12) Chlorocebus sabaeus
Analyze
Symbol: TSPAN12
Name: tetraspanin 12
RGD ID: 18342732
Description: ENCODES a protein that exhibits Wnt receptor activity (ortholog); INVOLVED IN maintenance of blood-brain barrier (ortholog); Norrin signaling pathway (ortholog); ASSOCIATED WITH Disease Susceptibility (ortholog); early myoclonic encephalopathy (ortholog); exudative vitreoretinopathy (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tetraspanin-12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12189,609,229 - 89,680,446 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2189,609,124 - 89,680,297 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604213,900,003 - 13,970,881 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TSPAN12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12189,609,229 - 89,680,446 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2189,609,124 - 89,680,297 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604213,900,003 - 13,970,881 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TSPAN12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387120,787,320 - 120,858,335 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7120,787,320 - 120,858,402 (-)EnsemblGRCh38hg38GRCh38
GRCh377120,427,374 - 120,498,198 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367120,214,610 - 120,285,413 (-)NCBINCBI36Build 36hg18NCBI36
Build 347120,021,325 - 120,092,128NCBI
Celera7115,236,877 - 115,307,696 (-)NCBICelera
Cytogenetic Map7q31.31NCBI
HuRef7114,790,536 - 114,861,356 (-)NCBIHuRef
CHM1_17120,360,669 - 120,431,498 (-)NCBICHM1_1
T2T-CHM13v2.07122,102,649 - 122,173,766 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27119,822,450 - 119,893,269 (-)NCBI
Tspan12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39621,771,390 - 21,879,557 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl621,771,394 - 21,852,514 (-)EnsemblGRCm39 Ensembl
GRCm38621,771,391 - 21,879,596 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl621,771,395 - 21,852,515 (-)EnsemblGRCm38mm10GRCm38
MGSCv37621,721,395 - 21,802,515 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36621,721,396 - 21,802,516 (-)NCBIMGSCv36mm8
Celera621,825,255 - 21,906,372 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map68.73NCBI
Tspan12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8451,279,562 - 51,355,030 (-)NCBIGRCr8
mRatBN7.2450,313,768 - 50,389,246 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl450,313,772 - 50,389,246 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx455,292,888 - 55,371,672 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0451,213,970 - 51,292,754 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0449,642,270 - 49,717,776 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0448,852,823 - 48,953,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl448,852,827 - 48,928,372 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0448,641,401 - 48,715,044 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4448,084,836 - 48,164,956 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1448,315,410 - 48,395,530 (-)NCBI
Celera445,518,037 - 45,592,649 (-)NCBICelera
Cytogenetic Map4q22NCBI
Tspan12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554792,570,937 - 2,635,857 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554792,570,937 - 2,636,884 (-)NCBIChiLan1.0ChiLan1.0
TSPAN12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26157,651,672 - 157,722,565 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan179,661,929 - 9,732,821 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07112,790,606 - 112,861,730 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17125,478,472 - 125,549,091 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7125,478,472 - 125,549,091 (-)Ensemblpanpan1.1panPan2
TSPAN12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11458,941,658 - 59,005,507 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1458,941,551 - 59,005,463 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1458,358,992 - 58,423,887 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01458,977,034 - 59,042,565 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1458,976,838 - 59,041,886 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11459,071,214 - 59,136,845 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01458,694,898 - 58,759,920 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01459,073,370 - 59,138,262 (-)NCBIUU_Cfam_GSD_1.0
Tspan12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511847,865,412 - 47,938,462 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366054,265,316 - 4,338,526 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366054,265,475 - 4,338,518 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPAN12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1826,046,703 - 26,112,918 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11826,046,645 - 26,112,924 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21827,651,287 - 27,717,509 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Tspan12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478315,226,852 - 15,285,931 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478315,226,927 - 15,285,931 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TSPAN12
1715 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 17 33 33 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000008861   ⟹   ENSCSAP00000006995
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2189,609,124 - 89,680,297 (-)Ensembl
RefSeq Acc Id: XM_007982707   ⟹   XP_007980898
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12189,609,229 - 89,680,446 (-)NCBI
Vero_WHO_p1.0NW_02366604213,900,003 - 13,970,881 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007982708   ⟹   XP_007980899
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12189,609,229 - 89,679,464 (-)NCBI
Vero_WHO_p1.0NW_02366604213,900,773 - 13,970,881 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038004440   ⟹   XP_037860368
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604213,900,083 - 13,970,881 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007980898 (Get FASTA)   NCBI Sequence Viewer  
  XP_007980899 (Get FASTA)   NCBI Sequence Viewer  
  XP_037860368 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006995
  ENSCSAP00000006995.1
RefSeq Acc Id: XP_007980898   ⟸   XM_007982707
- UniProtKB: A0A0D9REF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007980899   ⟸   XM_007982708
- UniProtKB: A0A0D9REF6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000006995   ⟸   ENSCSAT00000008861
RefSeq Acc Id: XP_037860368   ⟸   XM_038004440
- UniProtKB: A0A0D9REF6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010773 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008861.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1450.10 UniProtKB/TrEMBL
InterPro Tetraspanin UniProtKB/TrEMBL
  Tetraspanin/Peripherin UniProtKB/TrEMBL
  Tetraspanin_CS UniProtKB/TrEMBL
  Tetraspanin_EC2_sf UniProtKB/TrEMBL
KEGG Report csab:103226789 UniProtKB/TrEMBL
NCBI Gene TSPAN12 ENTREZGENE
PANTHER PTHR19282 UniProtKB/TrEMBL
  TETRASPANIN-12 UniProtKB/TrEMBL
Pfam Tetraspanin UniProtKB/TrEMBL
PIRSF Tetraspanin UniProtKB/TrEMBL
PRINTS TMFOUR UniProtKB/TrEMBL
PROSITE TM4_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48652 UniProtKB/TrEMBL
UniProt A0A0D9REF6 ENTREZGENE, UniProtKB/TrEMBL