Maf (MAF bZIP transcription factor)

Gene: Maf (MAF bZIP transcription factor) Chinchilla lanigera

Analyze

Symbol:

Maf

Name:

MAF bZIP transcription factor

RGD ID:

8753390

Description:

ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cell development (ortholog); inner ear development (ortholog); lens development in camera-type eye (ortholog); ASSOCIATED WITH autosomal recessive spinocerebellar ataxia 12 (ortholog); Ayme-Gripp syndrome (ortholog); benign epilepsy with centrotemporal spikes (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); RNA polymerase II transcription regulator complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

transcription factor Maf; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955522	2,514,313 - 2,519,694 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive spinocerebellar ataxia 12 (ISO)

Ayme-Gripp syndrome (ISO)

benign epilepsy with centrotemporal spikes (ISO)

cataract (ISO)

cataract 21 multiple types (ISO)

Cataract Microcornea Syndrome (ISO)

Colorectal Neoplasms (ISO)

developmental and epileptic encephalopathy 1 (ISO)

developmental and epileptic encephalopathy 28 (ISO)

Developmental Disabilities (ISO)

epilepsy (ISO)

esophageal cancer (ISO)

fibrodysplasia ossificans progressiva (ISO)

genetic disease (ISO)

intellectual disability (ISO)

intrahepatic cholestasis (ISO)

multiple myeloma (ISO)

schizophrenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell development (ISO)

inner ear development (ISO)

lens development in camera-type eye (ISO)

lens fiber cell differentiation (ISO)

megakaryocyte differentiation (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

positive regulation of gene expression (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of chondrocyte differentiation (ISO)

regulation of DNA-templated transcription (ISO)

Cellular Component

cytoplasm (ISO)

nucleus (ISO)

RNA polymerase II transcription regulator complex (ISO)

Molecular Function

DNA binding (ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (ISO)

double-stranded DNA binding (ISO)

identical protein binding (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Maf
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955522	2,514,313 - 2,519,694 (-)	NCBI	ChiLan1.0	ChiLan1.0

MAF
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	79,202,622 - 79,600,737 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	79,585,843 - 79,600,737 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	79,627,735 - 79,634,634 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	78,185,732 - 78,192,112 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	78,185,735 - 78,192,112	NCBI
Celera	16	63,926,698 - 63,933,512 (-)	NCBI		Celera
Cytogenetic Map	16	q23.2	NCBI
HuRef	16	65,384,643 - 65,391,409 (-)	NCBI		HuRef
CHM1_1	16	81,039,513 - 81,046,247 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	85,268,951 - 85,657,071 (-)	NCBI		T2T-CHM13v2.0

Maf
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	116,429,992 - 116,433,633 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	116,409,681 - 116,434,533 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	115,703,253 - 115,706,894 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	115,682,942 - 115,707,794 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	118,227,153 - 118,230,794 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	118,589,230 - 118,592,871 (-)	NCBI		MGSCv36	mm8
Celera	8	119,915,403 - 119,918,981 (-)	NCBI		Celera
Cytogenetic Map	8	E1	NCBI
cM Map	8	62.61	NCBI

Maf
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	60,259,200 - 60,622,145 (-)	NCBI		GRCr8
mRatBN7.2	19	43,353,867 - 43,713,162 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	43,360,342 - 43,712,365 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	50,534,463 - 50,536,407 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	51,187,718 - 51,189,656 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	53,428,393 - 53,430,309 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	48,179,826 - 48,200,995 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	48,194,804 - 48,196,748 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	58,976,694 - 58,999,741 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	45,859,510 - 45,861,454 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	45,864,390 - 45,866,335 (-)	NCBI
Celera	19	43,012,985 - 43,014,923 (-)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

MAF
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	89,333,211 - 89,339,592 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	95,251,476 - 95,257,980 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	60,188,494 - 60,194,871 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	79,618,156 - 79,624,460 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

MAF
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	71,965,291 - 71,982,903 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	71,965,500 - 71,981,735 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	71,912,571 - 71,918,461 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	72,271,569 - 72,277,450 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	72,271,341 - 72,302,366 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	72,211,442 - 72,217,331 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	72,047,056 - 72,052,965 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	72,524,417 - 72,530,335 (+)	NCBI		UU_Cfam_GSD_1.0

MAF
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	8,468,413 - 8,485,030 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	8,468,736 - 8,910,012 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	8,568,594 - 8,571,175 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAF
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	65,064,715 - 65,078,972 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666047	10,795,871 - 10,802,372 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Maf
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624746	7,653,690 - 7,672,404 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005409362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01068371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCB01002699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01402510	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005409362 ⟹ XP_005409419

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955522	2,514,313 - 2,519,694 (-)	NCBI

Sequence:

show sequence

GGCGGCCAGGCCGGCACCGGGGGCGGCGGCGGCGGAGGCGGCGGCGGCGGGGGCGCGGCGGGGG
CGGGGGGCGCCCTGCACCCGCACCACGCCGCGGGCGGCCTGCACTTCGACGACCGCTTCTCCGA
CGAGCAGCTGGTGACCATGTCCGTGCGCGAGCTGAACCGGCAGCTGCGCGGGGTCAGCAAGGAG
GAGGTGATCCGGCTGAAGCAGAAGAGGCGGACCCTGAAAAACCGCGGCTATGCCCAGTCCTGCC
GCTTCAAGAGGGTGCAGCAGAGACACGTCCTGGAGTCCGAGAAGAACCAGCTGCTGCAGCAGGT
CGACCACCTCAAGCAGGAGATCTCCAGGCTGGTGCGCGAGAGGGACGCGTACAAGGAGAAATAC
GAGAAGTTGGTGAGCAGCGGCTTCCGAGAAAACGGCTCGAGCAGCGACAACCCGTCCTCTCCAG
AGTTTTTCATAACTGAGCCCACTCGCAAGCTGGAGCCGCCAGTGGGATACGCTACATTTTGGAA
GCCCCAGCAACGTGTCCTTACCACTGTGTTCACAAAGTGAAATTTATGTGAGAGCTGTGCATTA
AAAAATATTATTATCATTATTATTATTACTATTATTACTATTATTATCTGCAGTTTTGGAGAAC
AACTTACCCCTGACTTCCGCTGAGACTCCTTTTTAAAGAACAATTATTGTGTTAGAGAAGTTTA
TTAAATGTATAAGCACTGTACTAATTAACAATTAACTCTGCCTCTTATCCGAGGATCTGATACA
CAGAACCATAGGAAGAGGCACCCATGCTTTTTGATTTATGATGTGCACAACTGAACAGGTGTGA
TTGCTTTCAACCTGGAGTATTAGTTGTAAAAAAATCCACTGAAATTACAAAAATATGTTTATGG
ACGCATATATATGAAGAAAAGTTTCCCAAAAAGTTAACAGCTAGCATTTTAAAAGCACATATAG
ACATGCACATTTTAAACAGTAAATTTTCATGCTTTATTGTTTCGCTGGCAGAGAATGATACTAA
GAAAAGAAATATTTGACTCTTCTCGCTAAACAGATGCCACTGGCAGAAGCTTTAGCTCCGCCTG
GCACCCTGGTTTTCTCGTAGGCCCTAGATAGTACTATATGTATCTGTGATGTCAGACGTGTTCA
TTTATCAAACACAGCTGTAAATGAAAACAATGTGTGGCCAAAATACAAAGTTAGTTAAATACAC
A

hide sequence

Protein Sequences


Protein RefSeqs	XP_005409419	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005409419 ⟸ XM_005409362
- Sequence:	show sequence MSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQ EISRLVRERDAYKEKYEKLVSSGFRENGSSSDNPSSPEFFITEPTRKLEPPVGYATFWKPQQRV LTTVFTK hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Maf	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Maf	MAF bZIP transcription factor		v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM