Mir6323 (microRNA 6323) - Rat Genome Database

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Gene: Mir6323 (microRNA 6323) Rattus norvegicus
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Symbol: Mir6323
Name: microRNA 6323
RGD ID: 7489032
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-6323
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,556,447 - 94,556,551 (+)NCBIGRCr8
mRatBN7.21181,052,065 - 81,052,169 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,052,065 - 81,052,169 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,789,229 - 89,789,333 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,442,587 - 82,442,691 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01181,503,722 - 81,503,826 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01184,827,032 - 84,827,136 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,827,032 - 84,827,136 (+)EnsemblRnor6.0rn6Rnor6.0
Celera1179,887,155 - 79,887,259 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


PMID:16381832   PMID:22605339   PMID:22908386  



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Predicted Targets
Summary Value
Count of predictions:5145
Count of gene targets:3829
Count of transcripts:4095
Interacting mature miRNAs:rno-miR-6323
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 18 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat

1 to 10 of 18 rows



ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
4 2 1 1 1 1 4 3 1


RefSeq Transcripts NR_106695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000074134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1181,052,065 - 81,052,169 (+)Ensembl
Rnor_6.0 Ensembl1184,827,032 - 84,827,136 (+)Ensembl
RefSeq Acc Id: NR_106695
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,556,447 - 94,556,551 (+)NCBI
mRatBN7.21181,052,065 - 81,052,169 (+)NCBI
Rnor_6.01184,827,032 - 84,827,136 (+)NCBI
Celera1179,887,155 - 79,887,259 (+)NCBI
Sequence:

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



Database
Acc Id
Source(s)
BioCyc Gene G2FUF-20700 BioCyc
Ensembl Genes ENSRNOG00000048889 Ensembl
miRBase MI0021847 ENTREZGENE
NCBI Gene Mir6323 ENTREZGENE
PhenoGen Mir6323 PhenoGen
RatGTEx ENSRNOG00000048889 RatGTEx
RNAcentral URS000075D25E RNACentral
  URS000075D5D7 RNACentral


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir6323  microRNA 6323  Mir6323  microRNA mir-6323  Name updated 61478 APPROVED
2013-12-10 Mir6323  microRNA mir-6323      Symbol and Name status set to provisional 70820 PROVISIONAL