Mir6316 (microRNA 6316) - Rat Genome Database

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Gene: Mir6316 (microRNA 6316) Rattus norvegicus
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Symbol: Mir6316
Name: microRNA 6316
RGD ID: 7489025
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-6316
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81266,506,305 - 266,506,405 (+)NCBIGRCr8
mRatBN7.21256,501,216 - 256,501,316 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1256,501,216 - 256,501,316 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1264,719,578 - 264,719,678 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01271,425,630 - 271,425,730 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01264,063,867 - 264,063,967 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01278,298,675 - 278,298,775 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1278,298,675 - 278,298,775 (+)EnsemblRnor6.0rn6Rnor6.0
Celera1252,197,787 - 252,197,887 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


PMID:16381832   PMID:22605339   PMID:22908386  



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Variants in Mir6316
2 total Variants

Predicted Targets
Summary Value
Count of predictions:6427
Count of gene targets:4581
Count of transcripts:4869
Interacting mature miRNAs:rno-miR-6316
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 31 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat

1 to 10 of 31 rows



endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
reproductive system
respiratory system
2 2 2 2 2 3 2


RefSeq Transcripts NR_106686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000075015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1256,501,216 - 256,501,316 (+)Ensembl
Rnor_6.0 Ensembl1278,298,675 - 278,298,775 (+)Ensembl
RefSeq Acc Id: NR_106686
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81266,506,305 - 266,506,405 (+)NCBI
mRatBN7.21256,501,216 - 256,501,316 (+)NCBI
Rnor_6.01278,298,675 - 278,298,775 (+)NCBI
Celera1252,197,787 - 252,197,887 (+)NCBI
Sequence:

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



Database
Acc Id
Source(s)
BioCyc Gene G2FUF-55294 BioCyc
Ensembl Genes ENSRNOG00000049017 Ensembl
miRBase MI0021838 ENTREZGENE
NCBI Gene Mir6316 ENTREZGENE
PhenoGen Mir6316 PhenoGen
RatGTEx ENSRNOG00000049017 RatGTEx
RNAcentral URS0000759D2C RNACentral
  URS000075D43E RNACentral


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir6316  microRNA 6316  Mir6316  microRNA mir-6316  Name updated 61478 APPROVED
2013-12-10 Mir6316  microRNA mir-6316      Symbol and Name status set to provisional 70820 PROVISIONAL