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Gene: Trhde (TRH-degrading enzyme) Mus musculus
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Symbol: Trhde
Name: TRH-degrading enzyme
RGD ID: 730937
Description: Predicted to have metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including peptide catabolic process; proteolysis; and regulation of blood pressure. Predicted to localize to cytoplasm and plasma membrane. Is expressed in cerebral cortex and hippocampus region. Orthologous to human TRHDE (thyrotropin releasing hormone degrading enzyme); INTERACTS WITH choline; ethanol; folic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9330155P21Rik; MGC40831; PAP-II; pyroglutamyl-peptidase II; thyroliberinase; thyrotropin-releasing hormone degrading ectoenzyme; thyrotropin-releasing hormone-degrading ectoenzyme; TRH-DE; TRH-degrading ectoenzyme; TRH-specific aminopeptidase
Orthologs:
Homo sapiens (human) : TRHDE (thyrotropin releasing hormone degrading enzyme)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Trhde (thyrotropin-releasing hormone degrading enzyme)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trhde (thyrotropin releasing hormone degrading enzyme)
Pan paniscus (bonobo/pygmy chimpanzee) : TRHDE (thyrotropin releasing hormone degrading enzyme)
Canis lupus familiaris (dog) : TRHDE (thyrotropin releasing hormone degrading enzyme)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trhde (thyrotropin releasing hormone degrading enzyme)
Sus scrofa (pig) : TRHDE (thyrotropin releasing hormone degrading enzyme)
Chlorocebus sabaeus (African green monkey) : TRHDE (thyrotropin releasing hormone degrading enzyme)
Heterocephalus glaber (naked mole-rat) : Trhde (thyrotropin releasing hormone degrading enzyme)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910114,234,725 - 114,638,207 (-)NCBI
GRCm3810114,398,820 - 114,802,302 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10114,398,823 - 114,802,307 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl10114,398,821 - 114,802,307 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710113,835,877 - 114,238,426 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610113,803,133 - 114,205,474 (-)NCBImm8
Celera10116,334,960 - 116,737,119 (-)NCBICelera
Cytogenetic Map10D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Trhde
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730937
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.