Zfp683 (zinc finger protein 683) - Rat Genome Database

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Gene: Zfp683 (zinc finger protein 683) Mus musculus
Analyze
Symbol: Zfp683
Name: zinc finger protein 683
RGD ID: 5146065
MGI Page MGI
Description: Enables promoter-specific chromatin binding activity. Involved in regulation of gene expression and regulation of lymphocyte differentiation. Acts upstream of or within NK T cell differentiation and natural killer cell differentiation. Predicted to be located in nucleus. Orthologous to human ZNF683 (zinc finger protein 683).
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: Gm13060; Hob; Hobit; novel zinc finger protein; predicted gene 13060
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394133,778,506 - 133,786,252 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4133,781,149 - 133,786,307 (+)EnsemblGRCm39 Ensembl
GRCm384134,051,195 - 134,058,941 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,053,838 - 134,058,996 (+)EnsemblGRCm38mm10GRCm38
MGSCv374133,607,109 - 133,614,855 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera4132,226,715 - 132,244,549 (+)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14610273   PMID:21677750   PMID:21873635   PMID:22885984   PMID:27102484   PMID:29056343   PMID:30051906   PMID:30692620   PMID:30810242   PMID:30891737   PMID:30899267   PMID:31810881  
PMID:32661361   PMID:34183415   PMID:34462601   PMID:34685654   PMID:34717799   PMID:35294229   PMID:35389518   PMID:35803932   PMID:37392736  


Genomics

Comparative Map Data
Zfp683
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394133,778,506 - 133,786,252 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4133,781,149 - 133,786,307 (+)EnsemblGRCm39 Ensembl
GRCm384134,051,195 - 134,058,941 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,053,838 - 134,058,996 (+)EnsemblGRCm38mm10GRCm38
MGSCv374133,607,109 - 133,614,855 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera4132,226,715 - 132,244,549 (+)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.5NCBI
ZNF683
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,361,634 - 26,374,518 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,361,634 - 26,374,522 (-)EnsemblGRCh38hg38GRCh38
GRCh37126,688,125 - 26,699,285 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,560,712 - 26,571,853 (-)NCBINCBI36Build 36hg18NCBI36
Celera125,084,470 - 25,095,611 (-)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef124,942,150 - 24,953,290 (-)NCBIHuRef
CHM1_1126,801,286 - 26,812,426 (-)NCBICHM1_1
T2T-CHM13v2.0126,199,081 - 26,211,983 (-)NCBIT2T-CHM13v2.0
Zfp683
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85151,558,880 - 151,569,937 (+)NCBIGRCr8
mRatBN7.25146,277,972 - 146,285,856 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,278,978 - 146,285,000 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05152,280,982 - 152,288,208 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05155,967,579 - 155,974,205 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45152,801,039 - 152,806,811 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5144,696,953 - 144,704,148 (+)NCBICelera
Cytogenetic Map5q36NCBI
Znf683
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,748,639 - 5,754,911 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,748,569 - 5,758,389 (-)NCBIChiLan1.0ChiLan1.0
ZNF683
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21200,487,226 - 200,510,164 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11199,585,427 - 199,608,336 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,622,548 - 25,636,106 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,690,359 - 26,703,755 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,690,359 - 26,703,755 (-)Ensemblpanpan1.1panPan2
ZNF683
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,656,842 - 73,667,621 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,658,525 - 73,667,605 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,233,501 - 70,244,296 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,219,802 - 74,230,587 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1271,044,851 - 71,055,565 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,050,469 - 72,061,255 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,054,013 - 73,065,017 (+)NCBIUU_Cfam_GSD_1.0
Znf683
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505845,026,456 - 45,034,310 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647410,851,249 - 10,859,092 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF683
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,758,979 - 83,765,855 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,756,865 - 83,765,905 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2677,434,849 - 77,443,031 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF683
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120106,336,441 - 106,411,217 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603310,011,743 - 10,019,382 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf683
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476410,382,733 - 10,388,608 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zfp683
335 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:225
Count of miRNA genes:214
Interacting mature miRNAs:223
Transcripts:ENSMUST00000105884
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
4141154Nba1_mNew Zealand Black autoimmunity 1 (mouse)Not determined131650724140879275Mouse
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
14696808Rbcn1_mrod bipolar cell number 1 (mouse)4131947311134047311Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
1301793Tlsr3_mthymic lymphoma suppressor region 3 (mouse)Not determined4129465811136864536Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
4142082Psds2_mpsoriasis-like skin disease severity 2 (mouse)Not determined4133154678137617995Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000105884   ⟹   ENSMUSP00000101508
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4133,781,149 - 133,786,307 (+)Ensembl
GRCm38.p6 Ensembl4134,053,838 - 134,058,996 (+)Ensembl
RefSeq Acc Id: XM_003084598
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv374133,607,109 - 133,614,855 (+)ENTREZGENE
RefSeq Acc Id: XM_003086379
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
Celera4132,226,715 - 132,244,549 (+)ENTREZGENE
Protein Sequences
Ensembl Protein ENSMUSP00000101508.2
GenBank Protein I7HJS4 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: ENSMUSP00000101508   ⟸   ENSMUST00000105884

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-I7HJS4-F1-model_v2 AlphaFold I7HJS4 1-458 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3650254 AgrOrtholog
Ensembl Genes ENSMUSG00000049410 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000105884.2 UniProtKB/Swiss-Prot
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
MGD MGI:3650254 ENTREZGENE
NCBI Gene 100503878 ENTREZGENE
PANTHER PR DOMAIN ZINC FINGER PROTEIN UniProtKB/Swiss-Prot
  PR DOMAIN ZINC FINGER PROTEIN 1 UniProtKB/Swiss-Prot
Pfam zf-C2H2 UniProtKB/Swiss-Prot
PhenoGen Zfp683 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt I7HJS4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-11-06 Zfp683  zinc finger protein 683  Gm13060  predicted gene 13060  Symbol and/or name change 5135510 APPROVED