SPINK4 (serine peptidase inhibitor Kazal type 4)

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Gene: SPINK4 (serine peptidase inhibitor Kazal type 4) Pan paniscus

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Symbol:

SPINK4

Name:

serine peptidase inhibitor Kazal type 4

RGD ID:

329345179

Description:

INVOLVED IN response to xenobiotic stimulus (ortholog); ASSOCIATED WITH acromesomelic dysplasia, Maroteaux type (ortholog); distal arthrogryposis type 1A (ortholog); frontotemporal dementia and/or amyotrophic lateral sclerosis 6 (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

serine protease inhibitor Kazal-type 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	91,353,771 - 91,358,753 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	91,359,713 - 91,364,695 (-)	NCBI		NHGRI_mPanPan1

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acromesomelic dysplasia, Maroteaux type (ISO)

distal arthrogryposis type 1A (ISO)

frontotemporal dementia and/or amyotrophic lateral sclerosis 6 (ISO)

galactosemia (ISO)

primary ciliary dyskinesia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

response to xenobiotic stimulus (ISO)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SPINK4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	91,353,771 - 91,358,753 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	91,359,713 - 91,364,695 (-)	NCBI		NHGRI_mPanPan1

SPINK4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	33,240,167 - 33,248,567 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	33,218,365 - 33,248,567 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	33,240,165 - 33,248,565 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	33,230,196 - 33,238,565 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	33,230,195 - 33,238,564	NCBI
Celera	9	33,170,395 - 33,178,768 (+)	NCBI		Celera
Cytogenetic Map	9	p13.3	NCBI
HuRef	9	33,197,153 - 33,205,532 (+)	NCBI		HuRef
CHM1_1	9	33,239,128 - 33,247,497 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	33,258,882 - 33,267,284 (+)	NCBI		T2T-CHM13v2.0

Spink4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	40,920,056 - 40,931,395 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	40,920,052 - 40,931,395 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	40,920,056 - 40,931,395 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	40,920,052 - 40,931,395 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	40,867,089 - 40,878,428 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	41,095,937 - 41,143,924 (+)	NCBI		MGSCv36	mm8
Celera	4	40,580,572 - 40,591,997 (+)	NCBI		Celera
Cytogenetic Map	4	A5	NCBI
cM Map	4	20.64	NCBI

Spink4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	60,811,899 - 60,860,823 (+)	NCBI		GRCr8
mRatBN7.2	5	56,043,936 - 56,064,841 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	55,981,624 - 56,064,795 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	58,010,977 - 58,031,900 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	59,830,126 - 59,851,051 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	59,824,235 - 59,845,122 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	57,238,221 - 57,252,654 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	57,239,086 - 57,250,662 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	61,770,297 - 61,782,009 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	58,314,305 - 58,325,973 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	58,314,483 - 58,326,152 (+)	NCBI
Celera	5	54,664,999 - 54,676,599 (+)	NCBI		Celera
Cytogenetic Map	5	q22	NCBI

Spink4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955472	2,406,279 - 2,415,668 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955472	2,406,279 - 2,415,668 (-)	NCBI	ChiLan1.0	ChiLan1.0

SPINK4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	50,340,068 - 50,345,777 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	50,340,145 - 50,345,777 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	48,967,880 - 48,975,762 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	51,277,984 - 51,285,866 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	51,278,074 - 51,285,866 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	49,942,377 - 49,950,251 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	49,809,310 - 49,817,196 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	50,574,406 - 50,582,288 (+)	NCBI		UU_Cfam_GSD_1.0

Spink4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	165,237,296 - 165,243,461 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936524	1,785,415 - 1,790,954 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936524	1,784,805 - 1,789,464 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SPINK4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	33,246,247 - 33,255,688 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	33,246,260 - 33,255,617 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	37,503,380 - 37,512,763 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Spink4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	37,998,891 - 38,008,535 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624736	37,988,002 - 38,010,277 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_055117113	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_055117113 ⟹ XP_054973088

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	11	91,353,771 - 91,358,753 (-)	NCBI
NHGRI_mPanPan1	9	91,359,713 - 91,364,695 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_054973088	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_054973088 ⟸ XM_055117113

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	SPINK4	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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