Mirlet7e (microRNA let-7e) - Rat Genome Database

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Gene: Mirlet7e (microRNA let-7e) Rattus norvegicus
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Symbol: Mirlet7e
Name: microRNA let-7e
RGD ID: 2325606
Description: INTERACTS WITH bisphenol A; bleomycin A2; cisplatin
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: rno-let-7e
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8167,350,229 - 67,350,321 (+)NCBIGRCr8
mRatBN7.2158,677,180 - 58,677,272 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx163,501,768 - 63,501,860 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,194,432 - 72,194,524 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0165,411,814 - 65,411,906 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0159,704,381 - 59,704,473 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0160,624,039 - 60,624,131 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera154,858,138 - 54,858,230 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mirlet7eRatbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of MIRLET7E geneCTDPMID:28505145
Mirlet7eRatbleomycin A2 decreases expressionEXP 6480464Bleomycin results in decreased expression of MIRLET7E mRNACTDPMID:25933445
Mirlet7eRatcisplatin increases expressionEXP 6480464Cisplatin results in increased expression of MIRLET7E mRNACTDPMID:24880025|PMID:27397436
Mirlet7eRatendosulfan affects expressionEXP 6480464Endosulfan affects the expression of MIRLET7E mRNACTDPMID:31464424
Mirlet7eRatfuran decreases expressionEXP 6480464furan results in decreased expression of MIRLET7E mRNACTDPMID:20562052
Mirlet7eRatparacetamol affects expressionEXP 6480464Acetaminophen affects the expression of MIRLET7E mRNACTDPMID:24863736
Mirlet7eRatparacetamol decreases expressionEXP 6480464Acetaminophen results in decreased expression of MIRLET7E mRNACTDPMID:27397436
Mirlet7eRatresveratrol multiple interactionsEXP 6480464plastochromanol 8 inhibits the reaction [Resveratrol results in decreased expression of MIRLET7E mRNA]; Resveratrol inhibits more ...CTDPMID:22050707
Mirlet7eRatresveratrol increases expressionEXP 6480464Resveratrol results in increased expression of MIRLET7E mRNACTDPMID:22050707
Mirlet7eRattetrachloromethane increases expressionEXP 6480464Carbon Tetrachloride results in increased expression of MIRLET7E mRNACTDPMID:22112502

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PMID:14691248   PMID:16381832   PMID:16766679   PMID:17604727   PMID:20403161   PMID:21827835   PMID:27384999  



.

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Taglnrno-let-7e-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830

Predicted Targets
Summary Value
Count of predictions:17026
Count of gene targets:8284
Count of transcripts:8899
Interacting mature miRNAs:rno-let-7e-3p, rno-let-7e-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 47 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat

1 to 10 of 47 rows





RefSeq Transcripts NR_031805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: NR_031805
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8167,350,229 - 67,350,321 (+)NCBI
mRatBN7.2158,677,180 - 58,677,272 (+)NCBI
Rnor_6.0159,704,381 - 59,704,473 (+)NCBI
Rnor_5.0160,624,039 - 60,624,131 (+)NCBI
Celera154,858,138 - 54,858,230 (+)NCBI
Sequence:


Database
Acc Id
Source(s)
BioCyc Gene G2FUF-61259 BioCyc
miRBase MI0000832 ENTREZGENE
NCBI Gene 100313991 ENTREZGENE
PhenoGen Mirlet7e PhenoGen
RNAcentral URS000000B1C9 RNACentral
  URS0000409B45 RNACentral
  URS000075CDF6 RNACentral


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-06-02 Mirlet7e  microRNA let-7e      Symbol and Name status set to provisional 70820 PROVISIONAL