Ndufs4 (NADH:ubiquinone oxidoreductase subunit S4) - Rat Genome Database

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Gene: Ndufs4 (NADH:ubiquinone oxidoreductase subunit S4) Heterocephalus glaber
Analyze
Symbol: Ndufs4
Name: NADH:ubiquinone oxidoreductase subunit S4
RGD ID: 18931659
Description: ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN adult behavior (ortholog); adult walking behavior (ortholog); brain development (ortholog); ASSOCIATED WITH brain disease (ortholog); COVID-19 (ortholog); developmental coordination disorder (ortholog); FOUND IN mitochondrial respiratory chain complex I (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247595,630,522 - 5,733,928 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ndufs4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247595,630,522 - 5,733,928 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NDUFS4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38553,560,639 - 53,683,338 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl553,560,633 - 53,683,338 (+)EnsemblGRCh38hg38GRCh38
GRCh37552,856,469 - 52,979,168 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36552,892,242 - 53,014,925 (+)NCBINCBI36Build 36hg18NCBI36
Build 34552,892,241 - 53,014,924NCBI
Celera549,810,070 - 49,932,765 (+)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef549,829,192 - 49,951,782 (+)NCBIHuRef
CHM1_1552,859,382 - 52,982,064 (+)NCBICHM1_1
T2T-CHM13v2.0554,388,486 - 54,511,162 (+)NCBIT2T-CHM13v2.0
Ndufs4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913114,424,331 - 114,524,630 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13114,424,331 - 114,524,794 (-)EnsemblGRCm39 Ensembl
GRCm3813114,287,795 - 114,388,094 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13114,287,795 - 114,388,258 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713115,078,003 - 115,178,302 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613115,409,528 - 115,508,921 (-)NCBIMGSCv36mm8
Celera13118,620,039 - 118,721,271 (-)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1364.12NCBI
Ndufs4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8247,684,420 - 47,794,914 (-)NCBIGRCr8
mRatBN7.2245,951,327 - 46,061,829 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl245,951,313 - 46,061,846 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx253,055,093 - 53,165,153 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0251,113,456 - 51,223,515 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0245,988,050 - 46,102,968 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0246,372,488 - 46,476,162 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl246,372,518 - 46,476,203 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0265,403,197 - 65,515,243 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4245,839,236 - 46,479,619 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera241,712,356 - 41,822,320 (-)NCBICelera
Cytogenetic Map2q14NCBI
Ndufs4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544613,764,907 - 13,864,824 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544613,764,907 - 13,864,824 (-)NCBIChiLan1.0ChiLan1.0
NDUFS4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2460,256,021 - 60,378,662 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1558,409,645 - 58,532,287 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0560,344,363 - 60,467,008 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1561,966,124 - 62,088,388 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl561,966,124 - 62,088,375 (-)Ensemblpanpan1.1panPan2
NDUFS4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1461,613,580 - 61,727,219 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl461,613,589 - 61,727,205 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha461,379,036 - 61,492,669 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0462,107,235 - 62,231,743 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1461,884,352 - 61,997,681 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0462,012,344 - 62,126,203 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0462,529,496 - 62,643,162 (-)NCBIUU_Cfam_GSD_1.0
Ndufs4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213204,892,598 - 204,995,733 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648013,827,743 - 13,932,238 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648013,829,093 - 13,932,202 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFS4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1632,874,450 - 32,987,828 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11632,874,418 - 32,985,638 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21634,963,225 - 34,992,577 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFS4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1449,851,012 - 49,967,533 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl449,851,014 - 49,967,590 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660821,152,990 - 1,272,340 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004848528   ⟹   XP_004848585
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247595,630,522 - 5,733,927 (-)NCBI
RefSeq Acc Id: XM_021261428   ⟹   XP_021117087
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247595,630,522 - 5,733,928 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004848585 (Get FASTA)   NCBI Sequence Viewer  
  XP_021117087 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB17297 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005407
Reference Protein Sequences
RefSeq Acc Id: XP_021117087   ⟸   XM_021261428
- Peptide Label: isoform X2
- UniProtKB: G5C6Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848585   ⟸   XM_004848528
- Peptide Label: isoform X1
- UniProtKB: G5C6Y6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003956 ENTREZGENE
Ensembl Transcript ENSHGLT00000005477 ENTREZGENE
Gene3D-CATH atu1810 like domain UniProtKB/TrEMBL
InterPro NADH_UbQ_FeS_4_mit-like UniProtKB/TrEMBL
  NDUFS4-like_sf UniProtKB/TrEMBL
NCBI Gene Ndufs4 ENTREZGENE
PANTHER NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL UniProtKB/TrEMBL
  NADH-UBIQUINONE OXIDOREDUCTASE UniProtKB/TrEMBL
Pfam NDUS4 UniProtKB/TrEMBL
UniProt G5C6Y6 ENTREZGENE, UniProtKB/TrEMBL