Gpi (glucose-6-phosphate isomerase) - Rat Genome Database

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Gene: Gpi (glucose-6-phosphate isomerase) Heterocephalus glaber
Analyze
Symbol: Gpi
Name: glucose-6-phosphate isomerase
RGD ID: 18931558
Description: ENCODES a protein that exhibits glucose-6-phosphate isomerase activity (ortholog); monosaccharide binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN erythrocyte homeostasis (ortholog); fructose 6-phosphate metabolic process (ortholog); glucose 6-phosphate metabolic process (ortholog); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); Animal Disease Models (ortholog); FOUND IN ciliary membrane (ortholog); cytosol (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247948,823,449 - 8,851,625 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247948,826,281 - 8,851,614 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:26763976   PMID:30032202  


Genomics

Comparative Map Data
Gpi
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247948,823,449 - 8,851,625 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247948,826,281 - 8,851,614 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
GPI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381934,359,718 - 34,402,413 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1934,359,480 - 34,402,413 (+)EnsemblGRCh38hg38GRCh38
GRCh371934,855,645 - 34,893,318 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361939,547,909 - 39,583,076 (+)NCBINCBI36Build 36hg18NCBI36
Build 341939,547,908 - 39,583,076NCBI
Celera1931,557,376 - 31,605,748 (+)NCBICelera
Cytogenetic Map19q13.11NCBI
HuRef1931,360,777 - 31,377,222 (+)NCBIHuRef
HuRef1931,390,807 - 31,399,974 (+)NCBIHuRef
CHM1_11934,857,156 - 34,895,165 (+)NCBICHM1_1
T2T-CHM13v2.01936,886,877 - 36,946,977 (+)NCBIT2T-CHM13v2.0
Gpi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39733,900,752 - 33,929,761 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl733,900,755 - 33,929,761 (-)EnsemblGRCm39 Ensembl
GRCm38734,201,327 - 34,230,336 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl734,201,330 - 34,230,336 (-)EnsemblGRCm38mm10GRCm38
MGSCv37734,986,346 - 35,015,324 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36733,910,918 - 33,939,022 (-)NCBIMGSCv36mm8
MGSCv36724,688,418 - 24,717,214 (-)NCBIMGSCv36mm8
Celera729,335,681 - 29,371,931 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.46NCBI
Gpi
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,965,389 - 95,996,932 (-)NCBIGRCr8
mRatBN7.2186,828,211 - 86,856,077 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,828,216 - 86,856,086 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx192,231,564 - 92,259,517 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,697,568 - 100,725,522 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,989,860 - 94,017,813 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0190,063,411 - 90,091,287 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl190,063,411 - 90,091,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0191,207,014 - 91,234,890 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4186,658,836 - 86,686,712 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1186,736,946 - 86,764,823 (-)NCBI
Celera181,194,482 - 81,222,306 (-)NCBICelera
Cytogenetic Map1q21NCBI
Gpi
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554683,980,999 - 4,008,652 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554683,980,999 - 4,007,553 (+)NCBIChiLan1.0ChiLan1.0
GPI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22040,351,367 - 40,402,743 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11942,351,411 - 42,404,890 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01931,301,469 - 31,355,362 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11940,024,584 - 40,080,598 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1940,024,584 - 40,080,598 (+)Ensemblpanpan1.1panPan2
GPI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,922,380 - 117,948,325 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,922,635 - 117,948,316 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1117,320,830 - 117,346,503 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01118,518,230 - 118,543,889 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1118,497,395 - 118,544,065 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11118,079,121 - 118,105,067 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,705,505 - 117,731,413 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01118,763,883 - 118,789,615 (-)NCBIUU_Cfam_GSD_1.0
Gpi
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,037,338 - 10,063,762 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365701,579,372 - 1,608,788 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365701,582,120 - 1,608,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl644,038,357 - 44,069,328 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1644,038,374 - 44,069,331 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2639,516,820 - 39,547,963 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q12NCBI
GPI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1629,404,067 - 29,451,290 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl629,403,500 - 29,453,162 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660737,177,821 - 7,221,208 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000021276   ⟹   ENSHGLP00000021073
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247948,823,449 - 8,851,625 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000021277   ⟹   ENSHGLP00000021074
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247948,827,191 - 8,851,519 (-)Ensembl
RefSeq Acc Id: NM_001310272   ⟹   NP_001297201
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247948,826,281 - 8,851,614 (-)NCBI
RefSeq Acc Id: XM_021239418   ⟹   XP_021095077
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247948,826,281 - 8,851,612 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001297201 (Get FASTA)   NCBI Sequence Viewer  
  XP_021095077 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AIZ08997 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021073
  ENSHGLP00100012089
Reference Protein Sequences
RefSeq Acc Id: NP_001297201   ⟸   NM_001310272
- UniProtKB: A0A0A7HRG4 (UniProtKB/TrEMBL),   G5BXL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021095077   ⟸   XM_021239418
- Peptide Label: isoform X1
- UniProtKB: G5BXL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000021074   ⟸   ENSHGLT00000021277
RefSeq Acc Id: ENSHGLP00000021073   ⟸   ENSHGLT00000021276


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015058 Ensembl, ENTREZGENE
  ENSHGLG00100008962 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000021276 ENTREZGENE
  ENSHGLT00100012231 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1390.10 UniProtKB/TrEMBL
InterPro G6P_Isomerase UniProtKB/TrEMBL
  G6P_Isomerase_C UniProtKB/TrEMBL
  Phosphoglucose_isomerase_CS UniProtKB/TrEMBL
  SIS_dom_sf UniProtKB/TrEMBL
  SIS_PGI_1 UniProtKB/TrEMBL
  SIS_PGI_2 UniProtKB/TrEMBL
KEGG Report hgl:101720720 UniProtKB/TrEMBL
NCBI Gene Gpi ENTREZGENE
PANTHER GLUCOSE-6-PHOSPHATE ISOMERASE UniProtKB/TrEMBL
  PTHR11469 UniProtKB/TrEMBL
Pfam PGI UniProtKB/TrEMBL
PRINTS G6PISOMERASE UniProtKB/TrEMBL
PROSITE P_GLUCOSE_ISOMERASE_1 UniProtKB/TrEMBL
  P_GLUCOSE_ISOMERASE_2 UniProtKB/TrEMBL
  P_GLUCOSE_ISOMERASE_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF53697 UniProtKB/TrEMBL
UniProt A0A0A7HRG4 ENTREZGENE, UniProtKB/TrEMBL
  G5BXL7 ENTREZGENE, UniProtKB/TrEMBL